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All Journal Vidyottama Sanatana: International Journal of Hindu Science and Religious Studies Svāsthya: Trends in General Medicine and Public Health
Panduyasa, I Gede
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Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Corticosteroids and glaucoma: How do treatments trigger ocular nerve damage? - A systematic literature review Putra, I Gede Satya Wijaya; Adnyana, I Made Dwi Mertha; Wahyudi, I Wayan; Suardana, Anak Agung Komang; Indrayanti, Ni Komang Rina; Prabowo, Sang Kompyang Yudistira Eddy; Panduyasa, I Gede; Widyantari, Dewa Ayu; Agustini, Desak Gede Dwi; Suwandani, Ni Made Ayu
Svāsthya: Trends in General Medicine and Public Health Vol. 1 No. 3 (2024): November 2024
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v1i3.22

Abstract

Corticosteroids are steroid hormone derivatives produced by the adrenal glands. Corticosteroids in the health sector have been widely utilized as anti-inflammatory agents because of their strong and rapid effects. This study aimed to identify the impact of long-term corticosteroid use on eye damage. This study uses a systematic literature review, which is guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) to the article screening process.  The data of this study, in the form of demographic variables, route of administration, steroid type, comorbidities, and patient risk factors, were descriptively analyzed. As a result, 15 of the 22 articles were selected for analysis. Chronic corticosteroid administration may precipitate optic neuropathy, manifesting as glaucoma, which is characterized by progressive structural degeneration of retinal ganglion cells (RGCs) and concomitant visual function deterioration. The locus of primary pathological insult in glaucomatous conditions is the optic nerve head, specifically at the optic disc. This anatomical site is notable for the abrupt 90-degree angular deviation of RGC axons as they transition from the retinal nerve fiber layer to their trajectory within the optic nerve proper. The use of corticosteroids can damage ocular nerve tissue through an increase in intraocular pressure (IOP) beyond 21 mmHg. This increase in IOP is due to changes in the microstructure of the trabeculum webbing, resulting in increased obstruction to the outflow of aqueous humor.
ETHNOECOLOGY IN BUYAN LAKE CONSERVATION Juliasih, Ni Ketut Ayu; Sudaryati, Ni Luh Gede; Sudiartawan, I Putu; Artha, I Made Dwi Purnama; Panduyasa, I Gede; Suyoga, I Putu Gede
Vidyottama Sanatana: International Journal of Hindu Science and Religious Studies Vol 8 No 1 (2024)
Publisher : UHN I Gusti Bagus Sugriwa Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25078/vidyottama.v8i1.3220

Abstract

Ethnoecology is the most recent approach to reveal the complexity of the relationship between belief systems (cosmos), knowledge/cognitive systems (corpus) and praxis (sosio-cultural practices) of local communities which can also be understood as local wisdom. The social phenomena and eco-cultural practices of the people in the Buyan Lake area also show this, so they are appropriately explained on the basis of ethnoecological theory. This qualitative study with descriptive interpretative was carried out for six months (May to October 2023) at the Buyan Lake Area locus. The results of the study show that the people in the Buyan Lake Area really respect the gods who are the rulers of nature who protect the environment of the Buyan Lake Area through the cosmos system, both regarding the mystical belief system revealed in the mythology of the forbidden wood, the gombang-rakrik dragons, the duwe animal, the yellow and the iron soan (springs and channels). Likewise, those who are glorified in the aspect of ruling deities in the Hindu pantheon such as Dewi Danu (lakes gods), Dewi Gangga (river gods), Dewi Gayatri (springs gods), Dewa Vishnu (water gods) and Dewa Sangkara (forest gods). The corpus system concerns their knowledge of the capabilities/availability and utilization of various water resources of Lake Buyan. These two ethnoecological systems form perceptions and underlie practical actions in the form of behavioural adaptations for the conservation of the Buyan Lake Area. The sustainable availability of plant resources around Lake Buyan and its fisheries is also part of its use for periodic rituals (ceremonial means).
Co-Authors Adnyana , I Made Dwi Mertha Agustini, Desak Gede Dwi Anak Agung Komang Suardana Artha, I Made Dwi Purnama I Wayan Wahyudi, I Wayan Indrayanti, Ni Komang Rina Ni Ketut Ayu Juliasih Ni Luh Gede Sudaryati Prabowo, Sang Kompyang Yudistira Eddy Putra, I Gede Satya Wijaya Sudiartawan, I Putu Suwandani, Ni Made Ayu Suyoga, I Putu Gede Widyantari, Dewa Ayu