Article Per Year (5 Year)
p-Index From 2020 - 2025
0.408
P-Index
This Author published in this journals
All Journal B-Dent, Jurnal Kedokteran Gigi Universitas Baiturrahmah
Bakti, Fitrah Utari
Unknown Affiliation
Dentistry

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
SALIVARY IL-6 AND IL-8 AS POTENTIAL BIOMARKERS FOR ORAL SQUAMOUS CELL CARCINOMA Bakti, Fitrah Utari; Setiadhi, Riani
B-Dent: Jurnal Kedokteran Gigi Universitas Baiturrahmah Vol 10, No 2 (2023): Vol 10 No 2, Desember 2023
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/jbd.v10i2.1460

Abstract

Introduction: Early identification of oral squamous cell carcinoma (OSCC) is a crucial factor influencing the disease's prognosis. The elevated levels of IL-6 and IL-8 in saliva are a result of their overproduction in the cancer microenvironment. The production of salivary cytokines, particularly IL-6 and IL-8, has a role in cancer development. These cytokines may also be used as biomarkers. The use of saliva as a biomarker is quite interesting because it is in direct contact with cancer cells, easy to access, non-invasive, and cost-effective. Aim: The aim of this literature review was to assess the potential of salivary IL-6 and IL-8 as biomarkers for OSCC early diagnosis. Review: The initiation of carcinogenesis in the oral cavity is actively repressed by inflammation and cell-mediated immunity. IL-6 and IL-8 are two important molecules involved in stromal-to-cancer cell communication. These cytokines play a major part in the growth, progression, metastasis, and recurrence of OSCC. Several studies have found that OSCC patients have higher levels of salivary IL-6 and IL-8 than healthy people and patients with an oral potentially malignant disorder (OPMD). Conclusion: Salivary IL-6 and IL-8 are very promising potential biomarkers for the early diagnosis of OSCC. Further research is still needed to validate and use these biomarkers clinically.
VIRTUAL REALITY HYPNOSIS PADA TATALAKSANA PASIEN LANJUT USIA DENGAN ORAL FRAILTY: LAPORAN KASUS Bakti, Fitrah Utari; Zakiawati, Dewi; Shafuria, Amira; Yubiliana, Gilang; Nur’aeny, Nanan
B-Dent: Jurnal Kedokteran Gigi Universitas Baiturrahmah Vol 10, No 2 (2023): Vol 10 No 2, Desember 2023
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/jbd.v10i2.1505

Abstract

Introduction: Oral frailty is a geriatric syndrome characterised by a decline in oral function associated with a decline in cognitive and physical function. Virtual reality hypnosis (VRH) is a current method that combines the benefits of virtual reality (VR) technology and hypnosis. Aim: This case report aims to describe the role of VRH in the management of elderly patients with oral frailty. Case and Management: A 65-year-old male patient came to the Oral Medicine Department with a chief complaint of dry mouth for the past three months. The patient often felt stressed because of his health problems. Intraoral examination showed frothy saliva, white plaque on the buccal and lateral mucosa of the tongue, missing teeth, and poor oral hygiene. Some additional examinations performed included the Indonesian Version of Summated Xerostomia Inventory (SXI-ID), Clinical Oral Dryness Score (CODS), sialometry, Depression Anxiety Stress Scale (DASS-21), and D-E-N-T-A-L oral frailty questionnaire. The test results showed that the patient had oral frailty. Case Management: Pharmacological therapy consisted of chlorine dioxide mouthwash, sucralfate syrup, and probiotic caplets. Non-pharmacological therapy consisted of instructions to maintain good oral hygiene, adopt a healthy lifestyle, and VRH. The relaxing effect of VRH was evidenced by the recording of increased alpha waves on quantitative electroencephalography (qEEG) during the procedure, and the results of SXI-ID, CODS, and DASS-21 at the last visit were normal. Oral frailty resolved after two weeks of treatment. The patient was also referred for oral care from the Departments of Periodontia, Prosthodontia, and Oral Surgery. Conclusion: VRH has an important role especially in the management of stress-induced xerostomia and pain in elderly patients with oral frailty.
Co-Authors Dewi Zakiawati, Dewi Gilang Yubiliana, Gilang Nur’aeny, Nanan Riani Setiadhi Shafuria, Amira