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FORMULASI SEDIAAN FACIAL WASH MENGGUNAKAN SARI JERUK NIPIS (Citrus aurantifolia Swingle) TERHADAP DAYA HAMBAT BAKTERI Propionibacterium acnes Suharyanisa; Harefa, Karnirius; Lina br Tarigan, Frida
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 2 No. 1 (2020): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Facial wash  merupakan sabun pembersih wajah yang ringan dan lembut yang berfungsi untuk menjaga kebersihan kulit. jeruk nipis yang sangat masam mengandung vitamin c yang bertindak sebagai antioksidan. Tujuan penelitian ini adalah Untuk mengetahui formulasi sediaan facial wash anti acnes dari perasan jeruk nipis (citrus aurantifolia swingle) dan Untuk mengetahui aktivitas perasan jeruk nipis dalam menghambat pertumbuhan bakteri propionibacterium acnes. Pembuatan sari jeruk nipis di lakukan secara sederhana yaitu menggunakan juicer. Masing-masing formulasi di lakukan replikasi sebanyak tiga kali. Pada penelitian ini formulasi dilaksanakan dengan perbedaan konsentrasi bahan aktif dengan F0 tanpa kandungan sari jeruk nipis, F1 mengandung 10% sari jeruk nipis, F2 mengandung 12,5% sari jeruk nipis, dan F3 mengandung 15%  sari jeruk nipis. Pengujian terhadap sediaan Facial wash meliputi uji organoleptis, uji pH, uji tinggi busa, uji homogenitas, uji iritasi, uji saponin, uji antibakteri. Hasil penelitian diperoleh bahwa semua sediaan Facial wash homogen, memiliki pH 6,5-7,2 dan stabil selama 4 minngu. Sediaan Facial wash sari jeruk nipis. Semua sediaan Facial wash sari jeruk nipis tidak mengiritasi kulit. Fasial wash sari jeruk nipis ( Citrus aurantifolia swingle ) dapat menghambat bakteri Propionibacterium acnes dengan diameter zona hambat kuat dengan konsentrasi 10%,12,5%,15%.
FORMULASI SPRAY GEL MINYAK DAUN NILAM (Pogostemon calbin Benth) DENGAN VARIASI KOSENTRASI KARBOPOL DAN HPMC Julia Susanti; Rosina Sitohang; Lina Br Tarigan, Frida; Yusfarida Laila Zhohrawati, Rosma
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 1 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Patchouli leaf oil spray gel formulation has been carried out, patchouli oil is one of the burns treatment. The purpose of this study was to determine whether the formation of a spray gel formulation of patchouli leaf oil with variance of the combination of carbopol 940 and HMPC 0.1%, 0.2%, 0.3% into a spray gel preparation and whether patchouli leaf oil can be used as a spray gel meets the requirements. quality of safety, this research is an experimental study which is carried out by testing organoleptic, homogeneity, viscosity, pH, spraying pattern, adhesive dispersion, stability, and irritation. The results of the spray gel preparations of carbopol 940 concentration variance and HPMC for organoleptic testing there was a cloudy white color change in the Cycling test, while the homogeneity test for all preparations was homogeneous, the viscosity test of the preparation showed that the 0.3% concentration did not meet the requirements, There was no change in the pH test on the preparations, namely neutral pH, tested for spraying patterns and the adhesion met the requirements of the 0.1% and 0.2% formulas. For the stability of the centrifugation there was no separation in the spray gel and for the irritation test there was no allergy in the respondent.
Uji Aktivitas Antibakteri Ekstrak Etanol Dan Etil Asetat Daun Mangkokan (Polyscias scutellaria (Burm.f.) Fosberg.) Terhadap Pertumbuhan Bakteri Proteus vulgaris DAN Trichophyton mentagrophytes Syarifah Roslianizar; Hestina; Lina Br Tarigan, Frida; Nur Putri Dewi
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 4 No. 1 (2022): JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Indonesia is a tropical country with a wide variety of plants, including the Mangkokan plant (Polyscias scutellaria (Burm.f.) Fosberg.). Mangkokan leaf (Polyscias scutellaria (Burm.f.) Fosberg.) is an ornamental or herbaceous plant. Mangkokan leaves contain compounds of alkaloids, flavonoids, saponins, and steroids/triterpenoids. These compounds are known to have antibacterial activity. The purpose of this study was to determine the antibacterial activity of the ethanolic and ethyl acetate extracts of the leaves of the Mangkukan (Polyscias scutellaria (Burm.f.) Fosberg.) against Proteus vulgaris and Trichophyton mentagrophytes bacteria and to determine the difference in the inhibition zones of the ethanol and ethyl acetate extracts of the leaves of the Mangkokan (Polyscias scutellaria (Burm.f.) Fosberg.) between the bacteria Proteus vulgaris and Trichophyton mentagrophytes. The extraction of the Mangkokan leaf was carried out by the maceration method using two solvents, ethanol 96% and ethyl acetate. The extracts obtained were screened for phytochemicals and tested for antibacterial activity against Proteus vulgaris and Trichophyton mentagrophytes using the agar diffusion method using paper discs with three repetitions and positive control administration of Ciprofloxacin and Ketoconazole. The results of the research on the diameter of the inhibition zone of the ethyl acetate extract showed the strongest antibacterial activity compared to the ethanol extract in inhibiting the growth of Proteus vulgaris and Trichophyton mentagrophytes. Antibacterial activity was tested by agar diffusion method using disc paper. Experiments using concentrations of 20%, 40%, 60%, and 80%. The difference in the zone of inhibition of the ethanol extract of the leaves of the Mangkokan (Polyscias scutellaria (Burm.f.) Fosberg.) against Proteus vulgaris bacteria was 9,4 mm, and for Trichophyton mentagrophytes it was 9,6 mm. The difference in the inhibition zone of the ethyl acetate extract of the leaves of the Mangkokan (Polyscias scutellaria (Burm.f.) Fosberg.) against Proteus vulgaris bacteria was 10,06 mm and for Trichophyton mentagrophytes it was 10,42 mm.