Article Per Year (5 Year)
p-Index From 2020 - 2025
0.61
P-Index
This Author published in this journals
All Journal JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL
Mainal Furqon
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Education Engineering Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Nursing Physics Public Health Social Sciences

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
FORMULASI SEDIAAN SAMPO ANTIKETOMBE EKSTRAK DAUN ALPUKAT (Persea americana Mill) DAN UJI AKTIVITASNYA TERHADAP JAMUR Pityrosporum ovale Mainal Furqon; Silitonga, Evawani Martalena; Br Tarigan, Frida Lina; Rini
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 2 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Avocado leaves have antifungal activity because they contain chemical compounds. This study aims to determine whether avocado leaf ethanol extract (Persea americana Mill) can be formulated info anti-dandruff shampoo preparations and determine whether avocado leaf ethanol extract ethanol has antifungal activity against pityrosporum ovale. This research is experimental in the form in the form of an organoleptic test, the results were obtained with a liquid form slightly thick with the smell of avocado extract and blackish brown in color the homogeneity test on the 4 preparations was obtained homogeneous. In the Ph test, the ph for F0 7 and FI, F2, and F3 was obtained 6. The foam heights were 11 cm, while at F2 and F2, and F3, it was 9 cm. The stabilility test. Were was no change in the preparation, and for the irritation test there was no change. Allergic to the respondent. Shampoo activity test on the four preparations obtained inhibition zones in shampoo preparations with can be concluded that avocado leaf extract shampoo has antifungal activity against the fungus pityrosporum ovale.
Aktivitas Penghambatan Enzim Protease 6lu7 Virus Sars-Cov-2 Oleh Senyawa Steroid Glikosida Dari Daun Afrika (Vernonia amygdalina Del.) Secara In Silico Mainal Furqon; Cut Masyithah Thaib; N Daely, Ruth Christiani
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 4 No. 1 (2022): JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Vernonia amygdalina Del. Isaplant from the Asteraceae family is a small shrub with dark green leaves and leathery bark that grows predominantly in Africa. This plant contains steroidgly cosides, such: as Vernodalin, Vernolide, Vernolepin, Vernomenin, Vernomydin, Vernodalol, Hydroxylvernolide,11,13-dihydroxylvernodalin, 4,15-dihydrovernodalin, 1,2,3,15,11,13,2’,3’, hexahydrovernodalin, dan 1,2,3,15,11,13,2’,3’-octahydro vernodalin. Sesquiterpene Lakton in African leaves (Vernonia amygdalina) have properties, among others, as antimicrobials. Objective:  The purpose of this study was to determine the inhibition of the SARS-CoV-26LU7 protease enzyme by Sesquiterpen Lakton compounds from African leaves using the in-silico tethering method. Method: The in-silicomooring process is carried out using the PLANTS program and visualized using the MOE 2008 program. The protease enzyme was downloaded through the Protein Data Bank (PDB) with code 6LU7. Two-and three-dimensional models were generated using the Marvin Sketch program. The resulting docking value is evaluated as a result of the docking process. Results: The results showed that the protease 6LU7 enzyme tethering of the SARS-CoV-2 virus could provide valid results in-silico. The Sesquiterpen Lakton compounds from Afri can leaves can inhibit the protease enzyme. The docking result is a bletovisualize of the binding amino acids. Conclusion: In this study, it can be concluded that the Sesquiterpen Lakton compounds from African leaves can inhibit the SARS-CoV-2 virus 6LU7 protease enzyme with a docking score close to the docking score of each comparator drug.
IDENTIFIKASI SIMPLISIA DAN UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN SAWO (Manilkara zapota L) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus Mainal Furqon; Martalena Silitonga, Evawani; Juniwati Barus, Darwita; Sihombing, Fransiska
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 1 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sawo (Manilkara zapota) is a fruit plant that belongs to the Sapotaceae family. Sapodilla plants are tropical plants that are easily adaptable to various temperatures, rainfall, soil, and soil salinity. This plant has been widely cultivated and used traditionally as medicine. Sapodilla plants are widely cultivated in yards, gardens and are very easy to find in the market. Staphylococcus aureus bacteria are gram positive bacteria, immobile, not spore-forming and capable of forming capsules, cocci-shaped and arranged like grapes, one of the causes of diarrhea is Staphylococcus aureus bacteria. To overcome this disease by providing antimicrobial agents of natural origin that can inhibit the growth of these bacteria. This study was conducted with the aim of knowing the antibacterial activity of the ethanol extract of rambutan seeds with concentrations of 45%, 50%, 55% and 60% against the growth of Staphylococcus aureus bacteria. This research method uses an experimental method, namely to determine the antibacterial activity of ethanol extract from sapodilla leaves against the growth of Staphylococcus aureus bacteria. This research used 96% ethanol as solvent. The test was carried out through several stages including material collection, preparation of simplicia, manufacture of ethanol extract from sapodilla leaf simplicia by maceration and testing of antibacterial activity against Staphylococcus aureus bacteria. Based on the identification of sapodilla leaf simplicia powder, there are trichomes or hair coverings, stomata and calcium oxalate crystals. Phytochemical screening test of the thick extract of sapodilla leaves contains a group of alkaloid compounds, flavonoids, saponins, steroids/triterpenoids and tannins. The results of the antibacterial activity test of sapodilla leaf extract against Staphylococus aureus bacteria had an average inhibitory activity at concentrations of 45% (9.4 mm), 50% (12.2 mm), 55% (14.8 mm) and 60% (16.3mm). As a comparison, Cloramfenocol 30 g was used to produce an inhibitory power of 20,18 mm and the best results obtained were at a concentration of 60% which had an inhibitory power of 16.3 mm
Co-Authors Br Tarigan, Frida Lina Cut Masyithah Thaib Juniwati Barus, Darwita Martalena Silitonga, Evawani N Daely, Ruth Christiani RINI Sihombing, Fransiska Silitonga, Evawani Martalena