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All Journal Jurnal Biologi Tropis SALUT: Journal of Social and Education
Ramdha, Ika Salsabila
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Social Sciences Other

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Article Review: Development of a new type of TB vaccine as a replacement for the BCG vaccine Sutanti, B. Novia Rahmadita; Ramdha, Ika Salsabila; Rizki, Alpha Alfi; Putri, Latifa Rahma; Lestari, Neli Aulia; Syaharani, Ninda; Sunarwidhi, Anggit Listyacahyani
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10884

Abstract

Tuberculosis (TB) remains a significant global public health threat. The existing BCG vaccine has limited effectiveness, particularly in preventing pulmonary TB in adults. This study aims to review the recent developments in the creation of new TB vaccines as alternatives to BCG. This research employs a systematic review method by collecting articles from the Google Scholar database. Inclusion criteria included articles published between 2014-2024 that are relevant to the development of new TB vaccines. Data analysis was conducted descriptively to identify potential vaccine candidates. Several new TB vaccine candidates have shown promising results, including TAT-Ag85B, MTBVAC, rBCG-LTAK63, and subunit vaccines such as Ag85A and LT70. These vaccines demonstrated increased immune responses and better protection compared to BCG in preclinical trials. Innovative approaches like the use of nanocarriers and prime-boost strategies also show potential in enhancing vaccine efficacy. The development of new TB vaccines indicates significant progress with several potential candidates that could replace or complement the BCG vaccine. However, further research is needed to evaluate the efficacy and safety of these vaccines in clinical trials in humans before they can be widely implemented.
STUDI LITERATUR: PENTINGNYA INTERNALISASI NILAI-NILAI PANCASILA DALAM KETAHANAN NASIONAL Ramdha, Ika Salsabila; Amalia, Marshanda Fitri; Putri, Baiq Ayu Wulan Maharani; Buana, I Gede Eka Surya; Rayes, Norina Shaumy Putri
Journal of Social and Education Vol. 2 No. 2 (2026): Journal of Social and Education
Publisher : Lembaga Riset dan Publikasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1234/knn6sy28

Abstract

Perkembangan globalisasi yang pesat telah membawa dampak besar terhadap berbagai aspek kehidupan, termasuk ideologi bangsa Indonesia. Arus informasi dan budaya asing yang tak terseleksi berpotensi melemahkan jati diri bangsa dan menurunkan semangat nasionalisme. Artikel ini bertujuan untuk mengkaji peran strategis internalisasi nilai-nilai Pancasila dalam memperkuat ketahanan nasional. Manfaat dari kajian ini adalah memberikan pemahaman ilmiah mengenai pentingnya penguatan ideologi Pancasila sebagai dasar pertahanan negara. Metode yang digunakan adalah systematic review dengan menelaah 15 jurnal ilmiah dan buku yang relevan dari kurun waktu 2015 hingga 2025, diperoleh melalui Google Scholar. Kriteria seleksi mencakup keterkaitan tema dan aksesibilitas penuh terhadap naskah. Hasil kajian menunjukkan bahwa internalisasi nilai-nilai Pancasila memiliki peran penting dalam membentuk karakter, meningkatkan kesadaran nasional, dan memperkuat ketahanan ideologis bangsa. Pembahasan juga menguraikan tantangan internalisasi di tengah derasnya arus globalisasi serta pentingnya strategi penguatan nilai Pancasila dalam berbagai bidang kehidupan. 
Co-Authors Amalia, Marshanda Fitri Buana, I Gede Eka Surya Lestari, Neli Aulia Putri, Baiq Ayu Wulan Maharani Putri, Latifa Rahma Rayes, Norina Shaumy Putri Rizki, Alpha Alfi Sunarwidhi, Anggit Listyacahyani Sutanti, B. Novia Rahmadita Syaharani, Ninda