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All Journal Jurnal Biologi Tropis Jurnal Kesehatan Tambusai
Syaharani, Ninda
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Article Review: Development of a new type of TB vaccine as a replacement for the BCG vaccine Sutanti, B. Novia Rahmadita; Ramdha, Ika Salsabila; Rizki, Alpha Alfi; Putri, Latifa Rahma; Lestari, Neli Aulia; Syaharani, Ninda; Sunarwidhi, Anggit Listyacahyani
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10884

Abstract

Tuberculosis (TB) remains a significant global public health threat. The existing BCG vaccine has limited effectiveness, particularly in preventing pulmonary TB in adults. This study aims to review the recent developments in the creation of new TB vaccines as alternatives to BCG. This research employs a systematic review method by collecting articles from the Google Scholar database. Inclusion criteria included articles published between 2014-2024 that are relevant to the development of new TB vaccines. Data analysis was conducted descriptively to identify potential vaccine candidates. Several new TB vaccine candidates have shown promising results, including TAT-Ag85B, MTBVAC, rBCG-LTAK63, and subunit vaccines such as Ag85A and LT70. These vaccines demonstrated increased immune responses and better protection compared to BCG in preclinical trials. Innovative approaches like the use of nanocarriers and prime-boost strategies also show potential in enhancing vaccine efficacy. The development of new TB vaccines indicates significant progress with several potential candidates that could replace or complement the BCG vaccine. However, further research is needed to evaluate the efficacy and safety of these vaccines in clinical trials in humans before they can be widely implemented.
Review Article: Analysis of The Food Additive Rhodamine B in Foods Circulated in The Public Kanata, Nur Ramdhani; Putri , Chairatun Hisyani; Agustiani, Eti; Nurain, Siti; Syaharani, Ninda; Sutanti, B. Novia Rahmadita; Putri, Ni Luh Eka Sudiawati; Maulidya, Selvir Anandia Intan
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11418

Abstract

Food safety is very important, especially when it comes to snacks that kids and adults eat a lot of. Rhodamine B is still often used as a food coloring, even though it has been banned because it can cause serious health problems, like liver damage and a higher risk of cancer from long-term exposure. This review seeks to investigate the occurrence of Rhodamine B in diverse food products available in the community and to evaluate the analytical methodologies employed in prior research. The research methodology employed is a literature review of national articles published between 2020 untill 2025, utilizing a literature search via Google Scholar with keywords pertinent to Rhodamine B and food analysis. Data were analyzed descriptively according to sample type and analytical methods, including color reaction tests, wool thread tests, thin layer chromatography (TLC), and UV-Vis spectrophotometry, along with the outcomes of Rhodamine B identification. The findings indicated that Rhodamine B was still present in various food items, particularly traditional red cakes, school snack crackers, unbranded jam, red velvet cakes, and certain steamed cakes. Layer cakes, jelly-based foods, cilok sauce, and shrimp paste, on the other hand, were said to not have Rhodamine B in them. This finding stresses the need for ongoing food monitoring and the use of good analytical methods.
EVALUASI PENGELOLAAN STOK OBAT KADALUWARSA DI INSTALASI FARMASI RSUD X Syaharani, Ninda; Saputra, Yoga Dwi; Hasina, Raisya; Mulyaningsih, Kismawati
Jurnal Kesehatan Tambusai Vol. 7 No. 1 (2026): MARET 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v7i1.54892

Abstract

Pengelolaan stok obat yang efektif dan efisien merupakan bagian penting dari pelayanan kefarmasian di rumah sakit untuk menjamin ketersediaan obat yang aman, bermutu, dan efektif. Obat kadaluwarsa dapat menyebabkan kerugian ekonomi dan menurunkan kualitas pelayanan. Pada tahun 2023, RSUD X mencatat sebanyak 111 item obat kadaluwarsa (0,46%) dari total 23.637 item, melebihi standar Kementerian Kesehatan RI (0%) namun masih berada di bawah ambang batas WHO (<1%). Penelitian ini bertujuan untuk mengevaluasi pengelolaan stok obat kadaluwarsa di Instalasi Farmasi RSUD X tahun 2023. Penelitian ini menggunakan desain deskriptif observasional dengan pendekatan cross-sectional. Data diperoleh dari catatan mutasi stok obat, laporan pemusnahan obat, serta wawancara dengan Kepala Instalasi Farmasi, petugas administrasi, dan petugas gudang. Analisis dilakukan dengan menghitung persentase obat kadaluwarsa dan membandingkan praktik pengelolaan dengan standar Kementerian Kesehatan RI dan WHO. Hasil penelitian menunjukkan terdapat 111 item obat kadaluwarsa (0,46%). Prosedur pemusnahan dan sebagian aspek penyimpanan telah sesuai dengan standar. Namun, masih terdapat kelemahan pada pelabelan obat yang mendekati kedaluwarsa, penerapan prinsip First Expired First Out (FEFO) dalam distribusi, pelaporan berkala, serta monitoring dan evaluasi rutin. Tidak ditemukan obat kadaluwarsa dari golongan narkotika dan psikotropika. Kesimpulannya, pengelolaan obat kadaluwarsa di RSUD X belum optimal dan memerlukan perbaikan melalui pelabelan khusus, distribusi berbasis FEFO secara konsisten, peningkatan koordinasi antarunit, serta monitoring rutin untuk menekan risiko kadaluwarsa.
Co-Authors Agustiani, Eti Hasina, Raisya Kanata, Nur Ramdhani Lestari, Neli Aulia Maulidya, Selvir Anandia Intan Mulyaningsih, Kismawati Nurain, Siti Putri , Chairatun Hisyani Putri, Latifa Rahma Putri, Ni Luh Eka Sudiawati Ramdha, Ika Salsabila Rizki, Alpha Alfi Saputra, Yoga Dwi Sunarwidhi, Anggit Listyacahyani Sutanti, B. Novia Rahmadita