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Systematic Literature Review: Validitas Prognostik NIHSS sebagai Prediktor Luaran Fungsional pada Pasien Stroke (Tinjauan Periode 2020–2025) Naomi Elfriede Sirait; TA Larasati; Laisa Azka; Fitria Saftarina
Journal of Medical Practice and Research Vol 1 No 2 (2025): December: Essentia: Journal of Medical Practice and Research
Publisher : CV SCRIPTA INTELEKTUAL MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65310/0kafkc80

Abstract

The National Institutes of Health Stroke Scale (NIHSS) is the standard instrument for stroke evaluation, yet its prognostic validity for functional outcomes continues to evolve with the shift from static to dynamic assessment. This systematic review aims to evaluate the prognostic validity of NIHSS (static vs. dynamic) and the influence of lesion location and biological factors on functional outcome prediction accuracy in global and Indonesian literature from 2020–2025. A Systematic Literature Review (SLR) design was employed following PRISMA 2020 guidelines. Searches were conducted across five databases (PubMed, Scopus, Web of Science, Garuda, ISJD) using keywords related to NIHSS and prognosis. Following rigorous selection, 20 articles (10 global, 10 Indonesian) were included for narrative synthesis. Data synthesis demonstrated the superiority of "Dynamic NIHSS" prognostic validity (24-hour score and Delta NIHSS) over admission scores (baseline) in predicting long-term outcomes and quality of life. Significant anatomical bias was identified; the threshold for favorable prognosis in posterior circulation stroke was higher (≤9) compared to anterior circulation (≤4). In Indonesia, NIHSS validity improved when combined with inflammatory biomarkers (NLR) and metabolic profiles. NIHSS validity is multidimensional.
Strategi Agromedicine untuk Pencegahan Fibrosis Paru pada Petani: Tinjauan Sistematis Modifikasi Alat Penyimpanan Gabah, Ventilasi Gudang, dan Efektivitas APD Respirator Rian Hendriyana Dwi Imanta; Indri Windart; Laisa Azka; Andreas Infianto
Journal of Medical Practice and Research Vol 1 No 2 (2025): December: Essentia: Journal of Medical Practice and Research
Publisher : CV SCRIPTA INTELEKTUAL MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65310/pse66b22

Abstract

Pulmonary fibrosis is a progressive respiratory disease associated with chronic inhalation of respirable dust and bioaerosols, posing a substantial occupational health risk for agricultural workers. Farmers involved in grain storage and handling are frequently exposed to organic dust, fungal spores, and endotoxins that can induce persistent alveolar inflammation and irreversible fibrotic changes. This systematic review examines agromedicine-based prevention strategies focusing on grain storage modification, warehouse ventilation, and the effectiveness of respiratory protective equipment. Evidence indicates that improved storage design and controlled ventilation systems significantly reduce airborne particulate concentrations, thereby lowering cumulative inhalation exposure. Respiratory protective devices, particularly high-efficiency respirators, provide additional individual-level protection, although their real-world effectiveness is strongly influenced by user compliance, proper fitting, and training. The findings highlight that reliance on personal protective equipment alone is insufficient to prevent long-term pulmonary damage. An integrated prevention framework combining engineering controls, environmental management, and occupational health education is essential to reduce the burden of pulmonary fibrosis among farmers and promote sustainable agricultural health practices.