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Peran Diet Kalium sebagai Pencegahan Resistensi Insulin Pramastha Candra Sasmita; ade yonata; TA Larasati
Medula Vol 11 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v11i4.299

The incidence and prevalence of type II diabetes is increasing worldwide that makes clinicians must try to identify, prevent, and treat patients appropriately. Diabetes mellitus is divided into 2 types, namely type I and type II. Type I diabetes mellitus occurs genetically because the body cannot produce insulin, while type II diabetes mellitus occurs due to acquired insulin resistance. Diabetes mellitus is a group of metabolic disorders with manifestations of hyperglycemia due to damage to pancreatic cells that causes insulin deficiency (type I diabetes) to insulin resistance (type II diabetes). High levels of potassium in the blood can help increase insulin secretion in pancreatic cells through a membrane potential that triggers depolarization, so that the sensitivity of β cells to the incidence of hyperglycemia increases. Potassium intake is very important in helping to increase insulin secretion of pancreatic cells so as to prevent hyperglycemia and reduce the risk of insulin resistance. Potassium as an electrolyte in the body, both serum levels and dietary intake are associated with the incidence of diabetes. Lower potassium levels have been found to be associated with an increased risk of diabetes in several studies.

Faktor Risiko Terjadinya Penyakit Hepatitis C Agusta Saraswati; TA Larasati; Suharmanto Suharmanto
Jurnal Penelitian Perawat Profesional Vol 4 No 2 (2022): Mei 2022, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v4i2.952

Hepatitis C merupakan masalah kesehatan masyarakat baik di dunia maupun di Indonesia. Hepatitis C adalah penyakit peradangan hati yang disebabkan oleh infeksi virus hepatitis C. Studi literatur ini bertujuan untuk mengetahui faktor risiko terjadinya penyakit hepatitis C melalui penelusuran literatur dari berbagai jurnal nasional dan internasional. Artikel yang digunakan adalah artikel tahun 2010-2022. Database yang digunakan adalah Pubmed, NCBI dan Google Scholar sebanyak 20 artikel yang memenuhi syarat. Artikel tersebut kemudian dilakukan analisis dan interpretasi dengan cara membuat rangkuman hasil penelitiannya. Penyakit hepatitis C dikaitkan dengan faktor sosiodemografi, lingkungan dan perilaku.

Analisis Multilevel Faktor Resiko Stunting di Indonesia: Sebuah Tinjauan Literatur Nelly Yuana; Ta. Larasati; Khairun Nisa Berawi
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 6, No 2: June 2021
Publisher : Universitas Aisyah Pringsewu

Stunting can cause poverty and create a vicious circle because stunting can increase morbidity, mortality and its consequences can extend to adulthood, thus increasing the risk of low newborns, infectious and non-communicable diseases, and decreased productivity and economic income. The prevalence of stunting in Indonesia in 2018 is 30.8% of the government's target of 14% in 2024. The aim of this study was to determine the risk factors for stunting based on multilevel analysis. Leading databases were searched electronically between 2017 and 2021, relevant health databases included PubMed, Google Scholar, and Cochrane using the keywords “multilevel analysis stunting”, “multilevel analysis of stunting determinants”, “multilevel analysis of risk factor stunting”. From 232 articles, 4 articles were identified and included in the review. Some of the risk factors that cause stunting in Indonesia, individual level: male gender, children aged 12-32 months, birth length less than 48 cm, low birth weight (LBW), number of household members more or equivalent with 5 people, living in households with more or equivalent with 3 children under 5 years of age, maternal height less than 150 cm, maternal age at pregnancy less than 20 years and more than 35 years, Antenatal care less than 4 times, household-level: slum, low parental education, community level: active posyandu, living in rural areas, and in areas outside Java-Bali.Abstrak: Stunting dapat meyebabkan kemiskinan dan menciptakan lingkaran setan, karena stunting bisa meningkatkan morbiditas, mortalitas serta konsekwensinya dapat meluas hingga dewasa, sehingga dapat meningkatkan resiko bayi baru lahir rendah, penyakit infeksi dan penyakit tidak menular, serta produktivitas dan pendapatan ekonomi yang menurun. Prevalensi stunting di Indonesia tahun 2018 sebesar 30,8% dari target pemerintah 14% di tahun 2024. Tujuan penelitian untuk mengetahui faktor resiko stunting berdasarkan analisis multilevel. Database terkemuka dicari secara elektronik antara tahun 2017 sampai 2021, database kesehatan yang relevan termasuk PubMed, Google Scholar, dan Cochrane dengan menggunakan kata kunci “multilevel analysis stunting”, “multilevel analysis determinan stunting”, “multilevel analysis risk factor stunting”. Dari 232 artikel didapati 4 artikel diidentifikasi dan dimasukkan dalam ulasan. Beberapa faktor resiko yang menyebabkan stunting di Indonesia, level individu : jenis kelamin laki-laki, anak usia 12-32 bulan, panjang badan lahir kurang dari 48 cm, berat badan lahir rendah (BBLR), jumlah anggota rumah tangga lebih dari 5 orang, tinggal dalam rumah tangga dengan 3 anak dibawah usia 5 tahun, tinggi badan ibu kurang dari 150 cm, usia ibu saat hamil kurang dari 20 tahun dan lebih dari 35 tahun, Antenatalcare kurang dari 4 kali, level rumah tangga rumah : kumuh, pendidikan orang tua yang rendah, level komunitas : keaktifan posyandu, tinggal dipedesaan, dan wilayah luar Jawa-Bali.

Hipertiroid pada Wanita Lansia Usia 60 Tahun dengan Pendekatan Kedokteran Keluarga di Campang Raya Josepin kevina inka wijaya; TA Larasati
Medula Vol 12 No 2 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i2.420

The number of people with hyperthyroidism according to the World Health Organization (WHO) worldwide in 2000 was estimated at 400 million, and it was more common in women than men with a ratio of 5: 1.7. This disease is important to be managed comprehensively because this disease is chronic so the patient must know about the disease and have the awareness to make lifestyle modifications so the treatment goals can be achieved and needs to be carried out through a family approach. This case report describes a woman Mrs. J 60 years old who was diagnosed with hyperthyroidism since 2 years ago came with complaints of heart palpitations, shaking hands, accompanied by complaints of frequent sweating even in a cold room. Mrs. J has internal risks in the form of inappropriate diet and eating habits of the patient, lack of knowledge about the causes, dangers and prevention of the disease suffered, as well as the treatment pattern of patients who only take medicine when there are complaints. External risk factors in patients, namely the lack of family support in reminding patients to manage a good lifestyle. So that pharmacological and non-pharmacological management is carried out holistically in accordance with the approach of family doctors and evidence based medicine. Enforcement of diagnosis and management of these patients has been carried out holistically, patient centered, family approach and community oriented based on several theories and recent research. In the process of behavior change, the patient has reached the trial stage.

Low Family Income Percapita As A Risk Factor For Stunting On 6-11 Toddlers Months In Rural Area Of Lampung Verra Rachma Indahsari; Ta Larasati
JKM (Jurnal Kebidanan Malahayati) Vol 9, No 2 (2023): Volume 9 No.2 April 2023
Publisher : Program Studi Kebidanan Fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkm.v9i2.9748

Latar Belakang: Lebih dari 140 juta balita di dunia mengalami stunting, yang didominasi Benua Asia dan Afrika. Indonesia menjadi negara ketiga se Asia Tenggara yang memiliki anak stunting sebesar 36,5%. UNICEF menyatakan bahwa stunting dapat disebabkan oleh faktor langsung dan faktor tidak langsung serta berisiko mengalami penyakit degeneratif.Tujuan untuk mengetahui faktor tidak langsung berupa pendidikan ibu, pendapatan perkapita keluarga, akses ke puskesmas, dan kunjungan ibu ke posyandu sebagai faktor risiko terjadinya stunting pada anak usia 6-11 bulan di Lampung Timur.Metode Penelitian ini menggunakan rancangan observasional analitik dengan desain case control. Jumlah sampel sebanyak 104 responden, terdiri dari 52 kelompok kontrol dan 52 kelompok kasus dengan teknik purposive sampling. Dalam penelitian ini menggunakan analisis multivariat dengan regresi logistik.Hasil uji regresi logistik menunjukkan bahwa pendapatan perkapita keluarga yang rendah sebagai faktor paling berisiko terjadinya stunting pada anak usia 6-11 bulan (p-value= 0,001 OR= 75,802; CI= 9,253-620,979), ibu yang tidak aktif berkunjung ke posyandu sebagai faktor risiko terjadinya stunting (p-value= 0,001; OR= 42,688; CI= 6,540-278,637), akses ke puskesmas yang kurang terjangkau sebagai faktor risiko terjadinya stunting (p-value=0,036; OR=9,195; CI= 1,157-73,076), dan pendidikan ibu yang rendah bukan sebagai faktor risiko penyebab stunting (p=.0,670; OR=1,571; CI=0,197-12,537). Kata Kunci: Pendapatan perkapita keluarga, stunting ABSTRACT Background: More than 140 million toddlers in worldwide experiencing stunting, dominated by the continents of Asia and Africa. Indonesia is the third country from Southeast Asia which has 36.5% stunting toddlers. UNICEF stated that stunting can caused by direct and indirect factors and the risk of developing degenerative disease. This study was conducted to know indirect factors which are maternal education, family income per capita, access to health center, (Puskesmas), and maternal visit to health center (Posyandu) as a risk factor for stunting in children aged 6-11 months in East Lampung. This study uses observational analytic design with case control. The number of sample was 104 respondents, consisting of 52 control groups and 52 case groups using purposive sampling technique. In this study, used multivariat analyzed with logistic regression. The result of logistic regression in this study indicate low family income percapita is the most risky factor for stunting in children aged 6-11 months (p-value=0.001; OR=75,802; CI= 9,253-620,979), mother’s inactivity for visiting health center (Posyandu) as a risk factor occurrence of stunting (p-value= 0,001; OR= 42,688; CI= 6,540- 278,637), health center that has low accressibility (Puskesmas) as a risk for stunting (p-value= 0,036; OR= 9,195; CI= 1,157-73,076), and low maternal education is not the risk factor for stunting (p=.0,670; OR=1,571; CI=0,197- 12,537) Keywords: family income percapita and stunting.

Treatment adherence and quality of life of patients taking antihypertensive medications Fitra Galih Nonasri; TA Larasati
Malahayati International Journal of Nursing and Health Science Vol 6, No 3 (2023)
Publisher : Program Studi Ilmu Keperawata Fakultas Kedokteran Universitas Malahayati Bandar Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v6i3.11635

Background: Hypertension as The Silent Killer characterized by blood pressure ≥140 mmHg/≥90 mmHg. Hypertensive people have lower quality of life compare to non-hypertensive people and they need an appropriate health behavior. Hypertensive medication without lifestyle modification and routine control of blood pressure increase cardiovascular complication even death that affecting quality of lifePurpose: To identify the characteristic and the dominant health behavior affecting quality of life among hypertensive farmer. Method: The minimum sample 103 hypertensive farmer ≥18 years old in Gunung Agung Village, Terusan Nunyai District, Central Lampung include in this cross sectional study after measuring the blood pressure. The data was taken by interviewing the participants using health seeking behavior questionnaire and Short Form-36, then multivariate analysis was performed using binary logistic regression.Results: A total of 103 hypertensive farmer dominant in the 1st grade of hypertension (63,2%), male (56,3%), 45-54 years old (35%), primary school as the last education background (45,6%), income rates ≤7 million/year (68%), and don’t take anti-hypertensive medications regularly (98,1%). Preventive and curative treatment as part of treatment efforts were the most dominant variable affecting quality of life (p=0,023; OR=0,096; CI=0,028-0,327).Conclusion: Quality of life of hypertension farmers was significantly related to attitude towards health (p=0.001; OR=0.218; CI=5.76-42.34), treatment effort (p=0.001; OR=1.86; CI=0.09-0 ,54), first time of treatment (p=0,001; OR=8,473; CI=3,10-23,17), and frequency of examination (p=0,023; OR=14,426; CI=5,81-40,16), where treatment efforts such as routine blood pressure control and taking anti-hypertensive drugs can improve quality of life (OR=4.208).

Penatalaksanaan Holistik Ibu Hamil Usia Remaja dengan Anemia Melalui Pendekatan Dokter Keluarga Ramadirga Thio Saba; TA Larasati
MAJORITY Vol 9 No 2 (2020): MAJORITY
Publisher : Majority

Show Abstract | Download Original | Original Source | Check in Google Scholar

Adolescent pregnancy is a global problem that occurs throughout the world. Pregnancy in adolescents poses a high risk to the health of both mother and baby. One of the risks of adolescent pregnancy is anemia. The state of anemia in adolescent pregnancy requires holistic management including patient's physical and psychological condition.This study is a case report. Primary data is obtained through anamnesis, physical examination, and home visits. Secondary data is obtained from the patient's medical records. Assessment based on holistic diagnosis from the beginning, process, and end of the study in a quality and quantitative way. Female patients in their teens conceived the first child at 27 weeks pregnant with body complaints felt limp, nausea, lack of appetite and dizziness felt early in pregnancy. Food intake during pregnancy is reduced due to frequent nausea and vomiting and can only eat with small portions and a rare frequency. Weight loss is ideal based on the calculation of the patient's BMI and the nutritional status of the patient based on LILA including normal. In patients there is an anemis conjunctiva. The patient's hemoglobin (Hb) levels are 9 g/dL which is relatively low for the II trimester. Enforcement of diagnosis and management in these patients has been done holistically, patient centered, family approach and in accordance with national guidelines and based on evidence based medicine. Changes in patient and family knowledge and behavior occur after patient centre and family approach interventions.

PENGARUH PEMBERIAN EKSTRAK BIJI KOPI ROBUSTA (Coffea canephora) LAMPUNG TERHADAP JUMLAH SEL PURKINJE CEREBELLUM TIKUS PUTIH (Rattus norvegicus) JANTAN GALUR Sprague dawley YANG DIINDUKSI MONOSODIUM GLUTAMAT Ilham Nugroho; Anggraeni Janar Wulan; TA Larasati; Khairun Nisa Berawi
MAJORITY Vol 11 No 2 (2023): MAJORITY
Publisher : Majority

Show Abstract | Download Original | Original Source | Check in Google Scholar

Excessive consumption of monosodium glutamate has a neurotoxic effect on the brain, one of which is the cerebellum. The caffeine and chlorogenic acid compounds contained in coffee beans have potential as an anti-inflammatory and neuroprotective agent thus protecting rats from neurotoxicity by glutamate involved with the death of cerebellar purkinje cells. This research is an experimental study with Completely Randomized Design (CRD) with a Posttest Only Control Group Design approach. The research subjects were 25 rats which were divided into 5 groups which are K- (aquadest 3,5 ml/day), K+ (MSG 4 g/kgBW/day), P1, P2, P3 (MSG 4 g/kgBW/day and robusta coffee extract lampung 1,5 ml/200gBW/day with a concentration of 0,03 g/ml; 0,06 g/ml; 0,12 g/ml respectively) with each group consisting of 5 rats. The number of purkinje cells is calculated by manual counting assisted by Image J software in 3 sections with 5 visual fields each in 400x magnification. The average number of cerebellar purkinje cells in K-, K+, P1, P2, and P3 were 22,72; 11,88; 22,44; 25,28; 27,12 respectively. One Way ANOVA test obtained p value=0,000 (p<0,05). Post Hoc LSD test on the number of purkinje cells showed a significant differences (p<0,05) between K- and K+ (p=0,000), K- and P3 (p=0,006), K+ and P1 (p=0,000), K+ and P2 (p=0,000), K+ and P3 (p=0,000), and P1 and P3 (p=0,004). There is an effect of robusta coffee extract (Coffea canephora) lampung againsts to the number of cerebellar purkinje cells in male rats strain (Rattus norvegicus) Sprague dawley induced by monosodium glutamate.

Systematic Literature Review: Validitas Prognostik NIHSS sebagai Prediktor Luaran Fungsional pada Pasien Stroke (Tinjauan Periode 2020–2025) Naomi Elfriede Sirait; TA Larasati; Laisa Azka; Fitria Saftarina
Journal of Medical Practice and Research Vol 1 No 2 (2025): December: Essentia: Journal of Medical Practice and Research
Publisher : CV SCRIPTA INTELEKTUAL MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65310/0kafkc80

The National Institutes of Health Stroke Scale (NIHSS) is the standard instrument for stroke evaluation, yet its prognostic validity for functional outcomes continues to evolve with the shift from static to dynamic assessment. This systematic review aims to evaluate the prognostic validity of NIHSS (static vs. dynamic) and the influence of lesion location and biological factors on functional outcome prediction accuracy in global and Indonesian literature from 2020–2025. A Systematic Literature Review (SLR) design was employed following PRISMA 2020 guidelines. Searches were conducted across five databases (PubMed, Scopus, Web of Science, Garuda, ISJD) using keywords related to NIHSS and prognosis. Following rigorous selection, 20 articles (10 global, 10 Indonesian) were included for narrative synthesis. Data synthesis demonstrated the superiority of "Dynamic NIHSS" prognostic validity (24-hour score and Delta NIHSS) over admission scores (baseline) in predicting long-term outcomes and quality of life. Significant anatomical bias was identified; the threshold for favorable prognosis in posterior circulation stroke was higher (≤9) compared to anterior circulation (≤4). In Indonesia, NIHSS validity improved when combined with inflammatory biomarkers (NLR) and metabolic profiles. NIHSS validity is multidimensional.

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