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All Journal Jurnal SainHealth Jurnal Analis Kesehatan
Nursalinda Kusumawati
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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Efek Pemberian Infusa Daun Andong Merah (Cordyline fruticosa L. A. Cheval) Terhadap Kadar Glukosa Pada Mencit (Mus musculus) Diabetes Sukarya, I Gede Andika; Ana Priska Ismi Farida; Nursalinda Kusumawati; Supri Hartini
Jurnal Analis Kesehatan Vol. 14 No. 2 (2025): JURNAL ANALIS KESEHATAN
Publisher : Department of Health Analyst, Politeknik Kesehatan, Kementerian Kesehatan Tanjungkarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jak.v14i2.5275

Abstract

Diabetes melitus adalah penyakit gangguan metabolisme akibat kekurangan hormon insulin, ditandai dengan kadar glukosa yang melebihi atau di bawah batas normal sehingga dapat menyebabkan hiperglikemia atau hipoglikemia. Upaya preventif sangat diperlukan untuk mengendalikan DM, salah satunya dengan pemanfaatan tanaman obat tradisional daun andong merah (Cordyline fruticosa L. A. Cheval). Daun andong merah diketahui mengandung senyawa aktif seperti saponin, tanin, dan flavonoid yang berpotensi menurunkan kadar glukosa darah. Penelitian ini dilakukan untuk mengetahui pengaruh pemberian infusa daun andong merah terhadap kadar glukosa pada mencit (Mus musculus) diabetes. Penelitian dilakukan secara kuantitatif dengan metode ekperimental menggunakan 48 mencit jantan diabetes yang dibagi menjadi tiga kelompok: kelompok mencit DM yang tidak diberi infusa, kelompok mencit DM yang diberi infusa, dan kelompok mencit DM yang diberi metformin. Infusa daun andong merah diberikan sebanyak 1 ml setiap pagi dan sore selama 14 hari. Kadar glukosa darah diukur menggunakan alat POCT. Hasil uji statistik menunjukkan terjadi penurunan dari 394,44 mg/dl menjadi 224,78 mg/dl dengan presentase penurunan sebesar 43,02 %. Dengan demikian, disimpulkan bahwa pemberian infusa daun andong merah memiliki pengaruh dalam menurunkan kadar glukosa darah pada mencit DM.
Hubungan Lama Menderita Diabetes Mellitus Tipe 2 Terhadap Kadar Natrium dan Klorida Di Wilayah Kerja Puskesmas Trauma Center Samarinda: Correlation Between Duration Of Type 2 Diabetes Mellitus And Sodium And Chloride Levels In The Working Area Of Puskesmas Trauma Center Samarinda M. Diki Ahan Apriliandi; Dwi Setiyo Prihandono; Maria Eka Suryani; Nursalinda Kusumawati
Jurnal SainHealth Vol. 10 No. 2 (2026): September 2026
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51804/jsh.v10i2.17456.117-124

Abstract

Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disease that may cause electrolyte imbalance due to prolonged hyperglycemia. This study aimed to determine the relationship between the duration of Type 2 Diabetes Mellitus and serum sodium and chloride levels among patients in the working area of Trauma Center Public Health Center, Samarinda. This analytical observational study employed a cross-sectional design. A total of 40 patients with Type 2 DM were selected using purposive sampling. Data collected included the duration of Type 2 DM and laboratory results of serum sodium (Na?) and chloride (Cl?) levels. Most respondents had normal sodium (85.0%) and chloride (85.0%) levels. Patients with a duration of Type 2 DM of ?5 years showed a higher proportion of low sodium and chloride levels than those with a duration of <5 years. Fisher’s Exact Test showed no statistically significant association between the duration of Type 2 DM and sodium levels (p = 0.661), whereas a statistically significant association was found with chloride levels (p = 0.020). In conclusion, the duration of Type 2 DM was associated with chloride levels but not with sodium levels. Routine electrolyte assessment is recommended as part of the metabolic monitoring of patients with Type 2 DM to support early detection and prevent complications.
Co-Authors Ana Priska Ismi Farida Dwi Setiyo Prihandono I Gede Andika Sukarya M. Diki Ahan Apriliandi Supri Hartini Suryani, Maria Eka