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All Journal Jurnal Neuroanestesi Indonesia Jurnal Praba: Jurnal Rumpun Kesehatan Umum
Arlinda Sari Wahyuni
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Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Comparison of the Values of Inflammatory Parameters C-Reactive Protein, Neutrophil Lymphocyte Ratio, Platelet Lymphocyte Ratio between Scalp Block Ropivacaine 0.5% and Intravenous Dexmedetomidine in Craniotomy Brain Tumors Muhamad Soleh; Rr Sinta Irina; Ester L.R. Silaen Silaen; Arlinda Sari Wahyuni
Jurnal Neuroanestesi Indonesia Vol 15, No 2 (2026)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v15i2.645

Abstract

Background and Objective: Craniotomy surgery can increase the body's inflammatory response through the neuroendocrine system. neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and C-reactive protein (CRP) are biomarkers of inflammation and immunosuppression. Scalp block using ropivacaine and intravenous dexmedetomidine are commonly used analgesic techniques to attenuate perioperative inflammatory responses. This study aims to determine the comparison of inflammatory marker values between ropivacaine 0.5% scalp block and intravenous dexmedetomidine in brain tumor craniotomySubject and Methods: This study used a single-blind clinical trial with a two-group posttest-only design. This study collected 36 research subjects who met the inclusion criteria. The subjects were divided into 2 groups, Group A received 0.5% ropivacaine scalp block and Group B received intravenous. Blood tests to assess inflammatory: markers were performed before and 24 hours postoperatively. The data obtained were analysed using SPSS version 20.Results: The change value of CRP in the scalp block ropivacaine 0.5% group was 24.71± 7.25 mg/l, while the change value of CRP in the dexmedetomidine group was 61.02 ± 17.81mg /l. The change value of PLR in the scalp block ropivacaine 0.5% group was 50.57 ± 57.91 while the change value of PLR in the dexmedetomidine group was 105.26 ± 64.81. There was a significant change of CRP and PLR values in the scalp block group compared to the dexmedetomidine group (p0.05). The change value of NLR in the scalp block group was 9.71 ± 5.75, while the change value of NLR in the demedetomidine group was 13.37 ± 5.55. There was no significant difference in the change value of NLR in the ropivacaine 0.5% scalp block group compared to dexmedetomidine (p0.05).Conclusion: Scalp block ropivacaine 0.5% has better results than intravenous dexmedetomidine administration in suppressing the inflammatory response in patients undergoing tumour craniotomy surgery.
Factors Associated With The Incidence Of Scabies At Hidayatullah Islamic Boarding School, Southeast Aceh Regency Minggu Noven Simorangkir; Ramona Dumasari Lubis; Arlinda Sari Wahyuni; Muhammad Ichwan; Hendri Wijaya; Nurcholisah Fitra; Ruslan Zuhair Pulungan; Abdul Rahman Ramdzan
Jurnal Praba : Jurnal Rumpun Kesehatan Umum Vol. 4 No. 2 (2026): Juni : Praba : Jurnal Rumpun Kesehatan Umum
Publisher : STIKES Columbia Asia Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62027/praba.v4i2.914

Abstract

Scabies is a contagious skin disease caused by Sarcoptes scabiei and is primarily transmitted through direct contact or contaminated fomites. The disease is commonly associated with overcrowded living conditions and poor personal and environmental hygiene. Scabies remains a public health concern and has been classified by the World Health Organization as a neglected tropical disease. This study aimed to determine the factors associated with scabies occurrence among students at Hidayatullah Islamic Boarding School, Southeast Aceh Regency. A quantitative study with a cross-sectional design was conducted from June 2024 to June 2025 involving 120 students selected through total sampling. Data were collected using structured questionnaires and analyzed using SPSS through univariate, bivariate analysis using the chi-square test, and multivariate analysis using logistic regression. The results showed significant associations between scabies occurrence and students’ knowledge, attitudes, personal hygiene, environmental sanitation, and support from boarding school management. Among these factors, personal hygiene was identified as the most dominant factor associated with scabies occurrence. These findings highlight the importance of improving students’ knowledge and attitudes, strengthening personal hygiene practices, maintaining adequate environmental sanitation, and enhancing support from boarding school management. Collaboration between boarding schools and healthcare providers is also essential to strengthen scabies prevention and control, particularly among newly admitted students.
Co-Authors Abdul Rahman Ramdzan Ester L.R. Silaen Silaen HENDRI WIJAYA Minggu Noven Simorangkir Muhamad Soleh Muhammad Ichwan NURCHOLISAH FITRA Ramona Dumasari Lubis Rr Sinta Irina Ruslan Zuhair Pulungan