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All Journal Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Journal of Innovative and Creativity Compromise Journal : Community Proffesional
Nuranti Rumela
universitas sari mutiara indonesia
Education Health Professions Languange, Linguistic, Communication & Media Mathematics Public Health Social Sciences Other

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Anti-Fungal Activity Test Of Cardamom (Amomum Cardamomum L.) Leaf Ethyl Acetate Fraction Against Candida Albicans And Pityrosporum Ovale Nuranti Rumela; Manahan Situmorang; Martin Suhendri; Aditiya Mawarni Zega
Journal of Innovative and Creativity Vol. 5 No. 2 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i2.2061

Abstract

Cardamom leaves (Amomum cardamomum (L.) Cardamom is a plant that is commonly used as a cooking spice and is also believed to have properties for treating various diseases, one of which is disease caused by fungi. The aim of this research is to determine the antifungal activity of ethanol extract of cardamom leaves against fungi Candida albicans and Pythyrovorum ovale to determine the effective inhibitory concentration of the ethanol extract of kitolod leaves in inhibiting it as an antifungal. The samples were extracted by the maceration method using 96% ethanol solvent. The antifungal activity test was carried out by the agar diffusion method using a paper backer. This experiment  consisted of three times Mixtures with respective concentrations of 20%, 40%, 80%, DMSO 10% as a negative control and Ketoconazole as a positive control. The results of the antifungal activity test showed that the ethanol extract of cardamom leaves was against Candida albicans fungi with concentrations of 20%, 40%, 80%. % respectively had an inhibition zone of (16.67 mm), (16.77 mm), (18.09 mm), positive control ketoconazole (21.40 mm), negative control 10% DMSO (0 mm). Meanwhile, the fungus Pythyrovorum ovale with concentrations of 20%, 40%, 80% respectively had an inhibition zone of (13.78 mm), (14.35 mm), (16.18 mm), positive control ketoconazole (19.86 mm), 10% DMSO negative control (0 mm). The results of the study showed that the ethanol extract of cardamom leaves had antifungal activity against Candida albicans and Pythyrovorum ovale.
Pemberdayaan Masyarakat Melalui Pelatihan Pembuatan Sediaan Gel Antijerawat Berbahan Herbal Lokal Suharyanisa Suharyanisa; Widya Fitri; Nuranti Rumela; Betharina br Tarigan
Compromise Journal Community Proffesional Service Journal Vol. 3 No. 1 (2025): Compromise Journal : Community Proffesional Service Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/compromisejournal.v3i1.562

Abstract

Acne is a common skin problem caused by excessive growth of Staphylococcus aureus on the skin due to increased sebum production. Dragon scale leaves (Drymoglossum piloselloides) contain active compounds such as saponins, phenols, tannins, and flavonoids, which have antibacterial and anti-inflammatory properties. This community service program aims to enhance public knowledge about the utilization of dragon scale leaf extract in acne gel formulations. The activities included education, a demonstration of gel preparation, and an evaluation of training effectiveness through pre-tests and post-tests. The evaluation results showed an increase in participant understanding from 20% to 75%, exceeding the targeted improvement. Active community participation indicates a strong interest in utilizing herbal plants as an alternative skincare solution, highlighting the potential for further development.
Formulasi dan Uji Aktivitas Antibakteri Sediaan Gel Antijerawat Ekstrak Etanol Daun Sisik Naga (Drymoglossum piloselloides (L.) Pressl.) terhadap Staphylococcus aureus Suharyanisa Suharyanisa; Widya Fitri; Nuranti Rumela; Betharina br Tarigan
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i4.560

Abstract

Acne appears due to increased sebum production on the skin and the growth of Staphylococcus aureus bacteria. The antibacterial activity of ethanol extract of dragon scale leaves (EEDSL) against Staphylococcus aureus bacteria provides strong inhibitory power. Dragon scale leaves (Drymoglossum piloselloides(L.) Pressl.)) can act as an anti-acne and its use as a preparation has not been widely carried out. This study aims to determine that EEDSL can be formulated as a gel preparation that meets the physicochemical quality requirements and that EEDSL gel preparations have antibacterial activity against Staphylococcus aureus. This study was conducted using an experimental method, sampling using the purposive sampling method in Kidupen Village, Juhar District, Karo Regency. Dragon scale leaf extract was obtained using the maceration technique with an ethanol solvent. EEDSL was formulated into a gel and then subjected to physical evaluation tests and antibacterial tests on staphylococcus aureus bacteria by looking at the diameter of the inhibitory power formed. The results of the study showed that the formulation of the anti-acne gel preparation was colorless, clear, and odorless obtained at F0. At F1; F2; and F3, a brown gel preparation was obtained with a semi-solid form and a distinctive EEDSL smell. The antibacterial activity test of EEDSL against Staphylococcus aureus showed an average value ± SD of the inhibition zone in each formula, namely at F0: 0.00 ± 0.00 mm; F1: 6.86 ± 0.17 mm; F2: 8.46 ± 0.19 mm; F3: 9.17 ± 0.18 mm; and positive control: 14.09 ± 0.23 mm. Based on the results of the data obtained, it can be concluded that EEDSL can be formulated as a gel preparation that meets the physicochemical quality requirements. Each concentration of ethanol extract of dragon scale leaves (Drymoglossum piloselloides (L.) Pressl.) has antibacterial activity against Staphylococcus aureus with a medium category.
Co-Authors Aditiya Mawarni Zega Betharina Br Tarigan Manahan Situmorang Martin Suhendri Suharyanisa Suharyanisa Widya Fitri