Article Per Year (5 Year)
p-Index From 2021 - 2026
0.751
P-Index
This Author published in this journals
All Journal Jurnal Multidisiplin Sahombu Journal of Pharmaceutical and Sciences. Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Journal of Innovative and Creativity
Nerly Juli Pranita Simanjuntak
Universitas Prima Indonesia
Agriculture, Biological Sciences & Forestry Arts Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Formulasi & Uji Antioksidan Facemist Ekstrak Etanol Buah Stroberi ( Fragaria X Ananassa Duch) Sebagai Pelembab Wajah Nerly Juli Pranita Simanjuntak; Revi Shafria Nabila; Novitaria Br Sembiring
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.7022

Abstract

Kulit memiliki fungsi utama sebagai pelindung tubuh terhadap berbagai pengaruh lingkungan, termasuk radikal bebas yang dapat mempercepat terjadinya penuaan dini. Salah satu pendekatan untuk meminimalkan efek stres oksidatif pada kulit adalah dengan pemanfaatan antioksidan yang berasal dari bahan alami. Buah stroberi (Fragaria × ananassa) dikenal mengandung senyawa fenolik dengan aktivitas antioksidan yang tinggi sehingga berpotensi digunakan sebagai bahan aktif dalam produk kosmetik. Penelitian ini bertujuan untuk mengembangkan sediaan face mist spray berbahan dasar ekstrak buah stroberi serta menilai aktivitas antioksidannya melalui metode DPPH dan mutu sediaan yang dihasilkan. Hasil penelitian menunjukkan bahwa ekstrak buah stroberi memiliki kemampuan antioksidan yang baik dan dapat diformulasikan secara stabil dalam bentuk face mist. Dengan demikian, face mist yang mengandung ekstrak buah stroberi berpotensi menjadi alternatif produk kosmetik alami untuk membantu menghambat proses penuaan dini pada kulit.
Antioxidant Activity Test of Ethanol Extract of Kesum Leaves (Polygonum Minus Huds) Using the DPPH Method Qori Hasanah Hasibuan; Nerly Juli Pranita Simanjuntak; Roy Indriyanto Bangar
Jurnal Multidisiplin Sahombu Vol. 6 No. 03 (2026): Jurnal Multidisiplin Sahombu, 2026
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kesum leaves (Polygonum minus Huds.) are herbal plants with potential as natural sources of antioxidants. This study aimed to evaluate the antioxidant activity of the ethanol extract of kesum leaves using the DPPH method and to identify the types of secondary metabolites present. Extraction was performed by maceration using 70% ethanol. Phytochemical screening was conducted qualitatively, while antioxidant activity was determined based on IC₅₀ values measured using a UV–Vis spectrophotometer at a wavelength of 517 nm, with vitamin C used as a reference standard. The results showed that the ethanol extract of kesum leaves contained alkaloids, flavonoids, tannins, triterpenoids, and steroids. The antioxidant activity test revealed that the ethanol extract had an IC₅₀ value of 7.9241 µg/mL, which was classified as having very strong antioxidant activity. In comparison, vitamin C exhibited a lower IC₅₀ value of 3.2886 µg/mL, indicating stronger antioxidant activity. These findings indicate that although the antioxidant activity of the ethanol extract of kesum leaves is lower than that of vitamin C, the extract still falls into the category of very strong antioxidants and has potential as a natural antioxidant source.
Aktivitas Nano Spray Gel Ekstrak Kulit Nanas (Ananas comosus L.) terhadap Pertumbuhan Bakteri Staphylococcus epidermidis pada Ulkus Diabetes Melitus Secara In Vitro Jesiska Muaratan; Astriani Natalia Br Ginting; Rena Meutia; Nerly Juli Pranita Simanjuntak
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 3 (2025): Juli : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i3.659

Abstract

Diabetic ulcers are complications of diabetes mellitus often associated with bacterial infections like Staphylococcus epidermidis. Pineapple peel is rich in secondary metabolites including flavonoids with potential antibacterial effects. This study aimed to assesss the antibacterial activity of nano spray gel made with pineapple peel extract against Staphylococcus epidermidis through in vitro testing. This research employed a laboratory experimental design using nano spray gel formulations at varying concentrations of 25%, 50%, and 75% of pineapple peel extract. Flavonoids, alkaloids, tannins, and saponins are confirmed by phytochemical analysis. Only the formulation with 75% demonstrated antibacterial activity effect, with an average inhibition zone of 8.61 mm (medium category). 25% and 50% formulations show no inhibition. Pure extract showed a 15.42 mm zone (strong), while the positive control (clindamycin) produced 29.69 mm (very strong) inhibition zone. PSA results indicated particle size averaged 1480 nm, exceeding the nanoemulsion standard (<500 nm). Nano spray gel with 75% pineapple peel extract demonstrated antibacterial activity against S. epidermidis, although the particle size did not meet nanoemulsion criteria.
Uji Aktivitas Antioksidan Lotion Ekstrak Etanol Daun Nilam (Pogostemon Cablin Benth) Dengan Metode DPPH (2,2-Diphenyl-1-Picrylhydrazil) Mawar Rahma Putri; Nerly Juli Pranita Simanjuntak; Novitaria Br Sembiring
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 2 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i2.1350

Abstract

Introduction: The skin, as the outermost organ of the human body, is continuously exposed to environmental factors, particularly sunlight and free radicals, which can induce oxidative stress leading to skin tissue damage and premature aging. Consequently, topical antioxidants are essential for skin protection. Patchouli leaves (Pogostemon cablin Benth.) are known to contain flavonoid compounds with potential antioxidant properties. Objective: This study aims to evaluate the antioxidant activity of patchouli leaf ethanol extract in lotion formulations using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Methods: This experimental research involved plant determination, extraction of patchouli leaves using the maceration method with 96% ethanol, phytochemical screening, formulation of lotion preparations with varying extract concentrations (1%, 2%, and 3%), physicochemical evaluation of the lotion formulations (including organoleptic properties, pH, homogeneity, viscosity, and spreadability), and antioxidant activity assessment using the DPPH radical scavenging assay. The antioxidant activity was expressed as IC₅₀ values, calculated through linear regression analysis. Results: Phytochemical screening revealed the presence of alkaloids, flavonoids, saponins, tannins, and triterpenoids/steroids in the ethanol extract. All lotion formulations demonstrated good physical stability and met the required quality standards for topical preparations, with pH values within the skin-friendly range (4.5-6.5), homogeneous texture, appropriate viscosity (2,000-50,000 cps), and adequate spreadability (5-7 cm). The ethanol extract of patchouli leaves exhibited very strong antioxidant activity with an IC₅₀ value of 0.011 µg/mL, while the formulated lotion maintained considerable antioxidant potential with an IC₅₀ value of 19.11 µg/mL. Conclusion: The ethanol extract of patchouli leaves possesses significant antioxidant activity and can be successfully formulated into a stable lotion preparation that retains its radical-scavenging properties. These findings suggest that patchouli leaf extract holds promising potential for development as a natural antioxidant active ingredient in topical cosmetic products, offering a viable alternative to synthetic antioxidants for skin protection against oxidative stress.
Co-Authors Astriani Natalia Br Ginting Jesiska Muaratan Mawar Rahma Putri Novitaria Br Sembiring Qori Hasanah Hasibuan Rena Meutia Revi Shafria Nabila Roy Indriyanto Bangar