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All Journal Jurnal Sains dan Teknologi Journal of Innovative and Creativity
Novitaria Br Sembiring
Universitas Prima Indonesia
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Formulasi & Uji Antioksidan Facemist Ekstrak Etanol Buah Stroberi ( Fragaria X Ananassa Duch) Sebagai Pelembab Wajah Nerly Juli Pranita Simanjuntak; Revi Shafria Nabila; Novitaria Br Sembiring
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.7022

Abstract

Kulit memiliki fungsi utama sebagai pelindung tubuh terhadap berbagai pengaruh lingkungan, termasuk radikal bebas yang dapat mempercepat terjadinya penuaan dini. Salah satu pendekatan untuk meminimalkan efek stres oksidatif pada kulit adalah dengan pemanfaatan antioksidan yang berasal dari bahan alami. Buah stroberi (Fragaria × ananassa) dikenal mengandung senyawa fenolik dengan aktivitas antioksidan yang tinggi sehingga berpotensi digunakan sebagai bahan aktif dalam produk kosmetik. Penelitian ini bertujuan untuk mengembangkan sediaan face mist spray berbahan dasar ekstrak buah stroberi serta menilai aktivitas antioksidannya melalui metode DPPH dan mutu sediaan yang dihasilkan. Hasil penelitian menunjukkan bahwa ekstrak buah stroberi memiliki kemampuan antioksidan yang baik dan dapat diformulasikan secara stabil dalam bentuk face mist. Dengan demikian, face mist yang mengandung ekstrak buah stroberi berpotensi menjadi alternatif produk kosmetik alami untuk membantu menghambat proses penuaan dini pada kulit.
Uji Total Flavonoid dan Aktivitas Antioksidan Fraksi Daun Brotowali sebagai Diabetes Ulkus Jhon Evan Iskandar Manullang; Novitaria Br Sembiring; Astriani Natalia Br Ginting
INSOLOGI: Jurnal Sains dan Teknologi Vol. 5 No. 2 (2026): April 2026
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v5i2.7866

Abstract

Diabetic ulcers are a chronic complication of diabetes mellitus characterized by impaired wound healing due to increased oxidative stress. One therapeutic approach that can be developed is the use of medicinal plants with antioxidant activity, such as Tinospora crispa leaves (Tinospora crispa), which contain flavonoids. This study aimed to determine the total flavonoid content and antioxidant activity of Tinospora crispa leaf fractions. Extraction was carried out using 96% ethanol, followed by fractionation using n-hexane, ethyl acetate, and water. Flavonoid content was determined using UV-Vis spectrophotometry using quercetin as a standard at a wavelength of 430.5 nm, while antioxidant activity was tested using the DPPH method. The results showed that the Tinospora crispa leaf aqueous fraction contained flavonoids of 0.2179 mg QE/g, with a linear calibration curve (R² = 0.997). Furthermore, the aqueous fraction demonstrated very strong antioxidant activity with an IC₅₀ value of ±16 µg/mL. Based on these results, the water fraction of brotowali leaves has the potential to be a source of natural antioxidants that can support the healing of diabetic ulcers by suppressing oxidative stress.
Co-Authors Astriani Natalia Br Ginting Jhon Evan Iskandar Manullang Nerly Juli Pranita Simanjuntak Revi Shafria Nabila