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All Journal Jurnal Ners Indonesian Journal of Global Health Research
Ervan Djafar
Universitas Negeri Gorontalo
Health Professions Medicine & Pharmacology Nursing

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Implementasi Dots Sebagai Determinan Utama Kepatuhan Pengobatan Fase Intensif Pasien Tbc Ervan Djafar; Margaretha Solang; Vivien Novarina Kasim; Teti Sutriyati Tuloli; Cecy Rahma Karim; Sunarto Kadir
Jurnal Ners Vol. 10 No. 1 (2026): JANUARI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i1.53634

Abstract

Tuberkulosis (TBC) masih menjadi beban kesehatan masyarakat terutama di negara dengan insidensi tinggi seperti Indonesia. Strategi Directly Observed Treatment Short-course (DOTS) yang direkomendasikan WHO berperan penting dalam meningkatkan keberhasilan pengobatan, namun kepatuhan selama fase intensif masih menjadi tantangan. Penelitian bertujuan menganalisis hubungan implementasi strategi DOTS dengan kepatuhan minum obat anti-TB pada fase intensif pada pasien TBC paru di Kabupaten Bone Bolango. Penelitian ini menggunakan desain kuantitatif analitik dengan pendekatan cross-sectional. Sampel sebanyak 75 responden diperoleh melalui total sampling. Data dikumpulkan menggunakan kuesioner terstruktur dan dianalisis menggunakan uji Chi-square dan regresi logistik. Hasil penelitian menunjukkan terdapat hubungan signifikan antara seluruh komponen DOTS dengan kepatuhan: komitmen pemerintah (p=0.006), pemeriksaan mikroskopis (p=0.003), pengawasan minum obat (p=0.000), ketersediaan obat (p=0.002), serta sistem pencatatan dan pelaporan (p=0.004). Faktor yang paling dominan adalah pengawasan minum obat, dengan p-value 0,001 dan OR = 0,133 (CI: 0.039 – 0.459). Implementasi DOTS sangat berhubungan dengan kepatuhan minum obat fase intensif. Penguatan peran pengawas minum obat, ketersediaan obat, dan sistem pelaporan diperlukan untuk meningkatkan keberhasilan pengobatan.
Implementation of Dots as the Primary Determinant of Treatment Adherence During the Intensive Phase of Tuberculosis Patients Ervan Djafar; Margaretha Solang; Vivien Novarina Kasim; Teti Sutriyati Tuloli; Cecy Rahma Karim; Sunarto Kadir
Indonesian Journal of Global Health Research Vol. 8 No. 3 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i3.1276

Abstract

Tuberculosis (TB) remains a major public health burden, particularly in high-incidence countries such as Indonesia. The World Health Organization–recommended Directly Observed Treatment Short-course (DOTS) strategy plays a crucial role in improving treatment success; however, patient adherence during the intensive phase of treatment remains a significant challenge. This study aimed to analyze the relationship between the implementation of the DOTS strategy and adherence to anti-tuberculosis medication during the intensive phase among pulmonary TB patients in Bone Bolango Regency. This study employed a quantitative analytical design with a cross-sectional approach. A total of 75 respondents were recruited using total sampling. Data were collected through a structured questionnaire and analyzed using Chi-square tests and logistic regression analysis. The findings demonstrated significant associations between all DOTS components and treatment adherence, including government commitment (p = 0.006), microscopic examination (p = 0.003), treatment supervision (p = 0.000), drug availability (p = 0.002), and recording and reporting systems (p = 0.004). Treatment supervision was identified as the most dominant factor influencing adherence, with a p-value of 0.001 and an odds ratio (OR) of 0.133 (95% CI: 0.039–0.459). The implementation of the DOTS strategy is strongly associated with adherence to anti-tuberculosis medication during the intensive phase of treatment. Strengthening the role of treatment supervisors, ensuring consistent drug availability, and improving recording and reporting systems are essential to enhance treatment success.
Co-Authors Cecy Rahma Karim Margaretha Solang Sunarto Kadir Teti Sutriyati Tuloli Vivien Novarina Kasim