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Uji Aktivitas Antioksidan pada Minuman Thai Thea dengan metode DPPH Rialita Lifiani; Lilik Septiana; Nurul Adzkia Ghearizky; Efilia Meirita; Resi Rizki Banjarani
JURNAL FARMASI DAN MAKANAN Vol 9 No 1 (2025): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i1.6970

Abstract

Thai tea is a tea-based beverage originating from Thailand that has gained global popularity. The key benefit of tea for health lies in its bioactive compounds, especially polyphenols, which are predominantly found in tea leaves. The DPPH (1,1-diphenyl-2-picrylhydrazyl) method is a simple and widely used analytical method for measuring antioxidant activity, as it is relatively easy, fast, and inexpensive. This study aims to evaluate the antioxidant activity of Thai tea beverages using the DPPH method. The research method used is experimental with a laboratory approach. The procedure includes the preparation of a DPPH solution, determination of the maximum wavelength of DPPH, measurement of blank solution absorbance, preparation of Quercetin as a standard solution, preparation of Thai tea test samples, and data analysis. The results showed the IC50 (Inhibitory Concentration) values for Thai Tea Sippin Original (47.56 ppm), Thai Tea Chatime Original (52.23 ppm), Thai Tea Kopi Kenangan Original (50.85 ppm), Thai Tea Es Teh Original (56.66 ppm), Thai Tea Dum-dum Original (54.73 ppm), and Quercetin standard (42.05 ppm). The results indicate that Thai tea beverages have antioxidant activity categorized as strong, particularly for Sippin Original, Chatime Original, Dum-dum Original, and Kopi Kenangan Original samples, while Sippin Original and the Quercetin standard are classified as very strong. Keywords: Thai Tea, Antioxidant, DPPH
Evaluasi Penggunaan Obat Antituberkulosis pada Pasien Tuberkulosis Dewasa di Dua Puskesmas Kota Pekanbaru Novtafia Endri; Nurul Adzkia Ghearizky; Winda Sri Wahyuni
JURNAL FARMASI DAN MAKANAN Vol 9 No 2 (2026): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i2.7928

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (MTB) and remains a major health problem in Indonesia. This study aims to evaluate the appropriateness of antituberculosis drug (OAT) use, including the appropriateness of the drug, dosage, and duration of treatment, and to analyze the relationship between the appropriateness of the duration of treatment and treatment outcomes. This study is an observational, descriptive-analytical study using retrospective medical record data from July 2024 to June 2025. A purposive sampling method was used, with a sample 259 patients who met the inclusion criteria. Data analysis was performed univariately to describe the distribution of study variables and bivariately to examine relationships between variables. The results of the univariate analysis showed that the appropriateness of drug use included 100% drug accuracy, 100% dose accuracy, and 81.1% treatment duration accuracy. The results of the bivariate analysis showed a significant relationship between the appropriateness of treatment duration and treatment outcomes (p-value < 0.001). Patients with appropriate treatment durations had a significantly greater chance of recovery than those with inappropriate treatment durations (OR = 9870). These findings indicate that the treatment process for adult tuberculosis (TB) patients at two community health centers in Pekanbaru City met the 2020 National Guidelines for Tuberculosis Management.