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Pembuatan Dan Evaluasi Pati Talas (Colocasia esculenta Schoot) Termodifikasi dengan Bakteri Asam Laktat (Lactobacillus sp) Wira Noviana Suhery; Deni Anggraini; Novtafia Endri
Jurnal Sains Farmasi & Klinis Vol 1, No 2 (2015): J Sains Farm Klin 1(2), Mei 2015
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (661.149 KB) | DOI: 10.29208/jsfk.2015.1.2.36

Abstract

Production and evaluation of modified taro (Colocasia esculenta Schott) starch by lactic acid bacteria (Lactobacillus sp) has been done. The purpose of this study was to observe the effect of lactic acid bacteria to the yield of taro starch and to evaluate physicochemical of starch. The evaluation which includes organoleptic, moisture content, pH, angle of repose, swelling power, gelatination temperature, amylose content, and examination of the surface shape of starch granules using SEM (Scanning Electron Microscope). The result showed that modified taro starch yield higher (19,12%) than native taro starch (11,79%). Modified taro starch of organoleptic examination showed better results where the smell was slighly reduced and the colour was white. Meanwhile, from the results of the evaluation of swelling power, gelatination temperature, and amylose content showed an increase. In addition, the modified taro starch granule were rougher due to some holes presented distinctively.
Rasionalitas Antibiotik Pasien Bronkitis Akut Anak Dengan Metode Gyssens Di RSIA Zainab Kota Pekanbaru Endri, Novtafia; Rahmawati, Ayu; Rahmawati, Noveri; Nesya, Nabilla Fadhia
The Journal Of Pharmacy Vol. 1 No. 1 (2023): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

According to WHO, as many as 13 million children in the world die every year and most of these deaths are in developing countries, where ISPA is one of the main causes of death by killing as many as 4 million children each year. Bronchitis ranks 6th out of 10 causes of death. However, Indonesia still has no reports on exact figures regarding this disease. This study aims to determine the accuracy of the use of antibiotics in pediatric patients with acute bronchitis based on the Gyssens method at RSIA Zainab Pekanbaru City. This type of research was non-experimental with data collection using a purposive sampling technique retrospectively. The results of the study based on a qualitative evaluation of the use of antibiotics in pediatric acute bronchitis patients at RSIA Zainab Pekanbaru City using the Gyssens method showed the quality of rational use of antibiotics found that 64 patients were declared rational ( category 0) and 5 patients were declared irrational. If possible further research regarding the rationality of using antibiotics in pediatric acute bronchitis patients at RSIA Zainab Pekanbaru City can be carried out using the DDD method or with a prospective approach so that monitoring of the patient's condition progress can be carried out from day to day.
Tingkat Pengetahuan Dan Perilaku Swamedikasi Penggunaan Obat Bebas Pada Masyarakat Di Kecamatan Simpang Kanan Kabupaten Rokan Hilir Ayu Rahmawati; Nursyafni; Novtafia Endri; Muhammad Arif; Nawwar Irfan; Wulandari, Tri Ayu; Fitratul Wahyuni
The Journal Of Pharmacy Vol. 2 No. 1 (2024): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

Self-medication is an act of self-medication carried out by the community to maintain health or manage disease based on personal diagnosis, using drugs repeatedly. This study aims to analyze the relationship between knowledge level and self-medication behavior using over-the-counter drugs in the community in Simpang Kanan District, Rokan Hilir Regency. The research was conducted observational with a cross-sectional approach, using quota sampling technique and questionnaires as instruments. The results showed that out of 90 respondents, 77.8% had good knowledge, 21.1% had sufficient knowledge, and 1.1% had poor knowledge. In terms of behavior, 81.1% had good behavior, while 18.9% had moderate behavior in self-medication. Analysis using the Chi-Square test resulted in a p-value of 0.002 (p<0.05), indicating a significant relationship between the level of knowledge and behavior of self-medication using over-the-counter drugs in the community in Simpang Kanan District, Rokan Hilir Regency.
Tingkat Pengetahuan Dan Kepatuhan Penggunaan Antibiotik Pada Masyarakat Di Kelurahan Limbungan Kecamatan Rumbai Timur Kota Pekanbaru Ayu Rahwamati; Lubis, Nursyafni; Putri Tri Adhani; Novtafia Endri
The Journal Of Pharmacy Vol. 2 No. 2 (2025): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

Tingginya penyakit infeksi menjadi salah satu masalah penyakit terbesar dan masuk kedalam sepuluh besar penyakit terbanyak di Indonesia. Berdasarkan data WHO 2015 menyatakan bahwa penyebab kematian pada anak <5 tahun di Indonesia disebabkan oleh penyakit infeksi dengan persentase 1-20 %. Tujuan dari penelitian ini yaitu untuk mengetahui hubungan tingkat pengetahuan dan kepatuhan antibiotik pada masyarakat di Kelurahan Limbungan Kecamatan Rumbai Timur Kota Pekanbaru. Penelitian menggunakan menggunakan metode survey cross- sectional dan jenis penelitian ini adalah kuantitatif. Sampel penelitian ini menggunakan 100 responden dengan instrumen penelitian menggunakan kuesioner. Analisa data penelitian yang dilakukan antara lain analisa univariat, bivariat dengan metode uji Chi-square. Hasil penelitian menunjukkan terdapat hubungan signifikan antara tingkat pengetahuan dengan kepatuhan dalam penggunaan obat antibiotik.
Kaitan Sosio-demografi dan Luaran Klinis pada Pasien Diabetes Melitus TIpe 2 (DMT2) di Rumah Sakit X di Pekanbaru Reza Laila Najmi; Novtafia Endri; Ahmad Muhaimin Rosyadi
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 17 No 2 (2025): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v17i2.871

Abstract

Type 2 Diabetes Mellitus (T2DM) is a chronic disease with a high global prevalence and is one of the leading causes of morbidity and mortality worldwide. Several sociodemographic factors, including age, sex, disease duration, educational level, and comorbidities, are believed to influence clinical outcomes in diabetic patients. This study aimed to analyze the association between sociodemographic characteristics and clinical outcomes among patients with T2DM. A cross-sectional study was conducted at Hospital X in Pekanbaru. The inclusion criteria were patients aged ≥18 years diagnosed with T2DM, receiving oral antidiabetic therapy for at least six months, and having complete medical records. Sociodemographic data were analyzed descriptively, and clinical outcomes were assessed based on HbA1c levels, categorized as “achieved” if HbA1c <7% and “not achieved” if ≥7%. The Chi-square test was used for statistical analysis. Of 95 patients, the majority were aged ≥45 years (84.2%), female (69.5%), and had a disease duration of ≥6 years (83.2%). Target HbA1c was more frequently achieved among female patients (60.6%), those aged ≥45 years (60%), with disease duration <6 years (75%), general educational level (60.2%), and without comorbidities (59.7%). However, no significant association was found between sociodemographic characteristics and achievement of HbA1c targets (p>0.05). Although certain sociodemographic groups tended to achieve better clinical outcomes, the study found no significant relationship between sociodemographic factors and clinical outcomes in T2DM patients. Further research considering lifestyle factors and pharmacological therapy is recommended.
17-2 Analisis Perbandingan Biaya Riil dan Tarif Ina-Cbg’s pada Pasien Rawat Jalan Onkologi dengan Terapi Morfin Sulfat (Mst) di RSUD Arifin Achmad Provinsi Riau Meirita, Efilia; Endri, Novtafia; Hari, Dewi Gulyla; Lifiani, Rialita
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 17 No 2 (2025): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v17i2.873

Abstract

Health service financing through the INA-CBG's (Indonesia Case-Based Groups) system aims for efficiency and transparency in the National Health Insurance (JKN) system. However, in practice, there are often discrepancies between INA-CBG's rates and the real costs incurred by health facilities, especially in oncology patients with Morphine Sulfate (MST) therapy. This study aims to analyze the comparison of real costs and INA-CBG's tariffs for oncology outpatients with morphine sulfate therapy (MST) at RSUD Arifin Achmad Riau Province. This study used descriptive observational research method with retrospective data collection obtained from medical records of oncology outpatients who received Morphine Sulfate (MST) therapy 10 mg and 15 mg tablets during the period January-March 2024. The data were analyzed by comparing the real costs incurred by the hospital with the rates paid by BPJS through the INA-CBG's system and the Mann-Whitney U test was performed. The results of the analysis showed that there was a significant difference between real costs and INA-CBG's tariffs. The average real cost of drugs (MST) was higher than the INA-CBG's tariff. The real cost of drugs that exceeded the INA-CBG's tariff amounted to 481 people, with a total cost difference (loss) of IDR 218,155,324. There was a difference between real costs and INA-CBG's rates (p = .047) and INA-CBG's rates (p = .113).
Edukasi Penggunaan Obat dan Herbal Tradisional yang Aman pada Diabetes Mellitus bagi Siswa SMK Muhammadiyah 3 Terpadu Pekanbaru Restu Anisa Putri; Ayu Rahmawati; Nursyafni Lubis; Novtafia Endri
Jurnal Pengabdian Magister Pendidikan IPA Vol 9 No 1 (2026): Januari - Maret 2026
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v9i1.14607

Abstract

Diabetes mellitus is a chronic disease that requires proper management, including correct medication use. Early education for vocational high school students is important to build awareness about safe medication use. The purpose of this community service activity was to increase students' knowledge about the safe use of diabetes mellitus medications, including Beyond Use Date (BUD), insulin storage, and traditional herbal medicines. The method used was lectures and discussions with a pre-post test design. Respondents were 32 grade X students from SMK Muhammadiyah 3 Terpadu Pekanbaru. Data were analyzed using paired t-test. Results showed a significant increase in knowledge scores from 73.98±3.13 to 87.04±7.47 (p<0.001) with Cohen's d=1.76. The proportion of students with good knowledge category increased from 3.1% to 81.2%. This education program was highly effective in increasing students' knowledge about the safe use of diabetes mellitus medications.
Analisis Penggunaan Obat Antihipertensi Dan Outcome Klinisnya Pada Pasien Di RSUD Rokan Hulu Provinsi Riau Novtafia Endri; Lubis, Nursyafni; Rahmadhani, Sari; Ratna Sari
The Journal Of Pharmacy Vol. 3 No. 1 (2025): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

Hipertensi merupakan salah satu masalah kesehatan utama yang memerlukan pengelolaan terapi yang rasional untuk mencapai outcome klinis yang optimal. Penelitian ini bertujuan untuk menganalisis pola penggunaan obat antihipertensi, tingkat rasionalitas terapi, serta hubungannya dengan outcome klinis pada pasien hipertensi di RSUD Rokan Hulu Provinsi Riau. Penelitian ini menggunakan desain cross-sectional retrospektif dengan data rekam medis pasien rawat jalan periode Januari–Desember 2024. Sebanyak 104 pasien yang memenuhi kriteria inklusi dianalisis. Evaluasi rasionalitas terapi meliputi ketepatan indikasi, pemilihan obat, dosis, dan interval pemberian. Outcome klinis dinilai berdasarkan pencapaian target tekanan darah. Hasil penelitian menunjukkan bahwa ketepatan indikasi mencapai 100%, ketepatan dosis 98,1%, dan ketepatan interval 99%, namun ketepatan pemilihan obat masih 80,8%. Kombinasi dua obat merupakan regimen paling banyak digunakan. Tidak terdapat hubungan yang signifikan antara karakteristik pasien dengan ketepatan penggunaan obat, namun terdapat hubungan antara ketepatan terapi dan outcome klinis. Evaluasi penggunaan obat antihipertensi penting untuk meningkatkan kualitas pelayanan dan hasil terapi pasien hipertensi.