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All Journal Jurnal Sain Veteriner Media Kedokteran Hewan
Tito Suprayoga
Universitas Riau
Medicine & Pharmacology Veterinary

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Concurrent Multidrug-Resistant Pseudomonas aeruginosa and Klebsiella pneumoniae subsp. Pneumoniae Infections in a 3-year-old Domestic Shorthair Cat in Pekanbaru, Riau, Indonesia: A Case Report Rifia Fani; Tito Suprayoga
Media Kedokteran Hewan Vol. 37 No. 2 (2026): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v37i2.2026.224-232

Abstract

Multidrug-resistant Gram-negative bacterial infections, especially those caused by Klebsiella pneumoniae and Pseudomonas aeruginosa, are becoming a problem in veterinary medicine. There are still not many reports of cats having multiple multidrug-resistant infections at the same time, especially in Indonesia. This case report presents a 3-year-old male domestic shorthair cat with chronic purulent nasal discharge, dyspnea, and tachycardia, unresponsive to empirical antibiotic treatment with amoxicillin–clavulanic acid. Thoracic radiography showed that both lungs had increased opaque. Nasal swab samples from both nostrils were cultured on blood agar, MacConkey agar, and desoxycholate agar. We used an automated system (bioMérieux VITEK® 2 Compact) to identify the bacteria and test their susceptibility to antibiotics by determining the minimum inhibitory concentration. Pseudomonas aeruginosa and Klebsiella pneumoniae subsp. pneumoniae, both exhibiting resistance to various antimicrobial classes, including β-lactams, aminoglycosides, fluoroquinolones, sulfonamides, and monobactams. Both isolates were sensitive to meropenem. Targeted therapy with intravenous meropenem (5 mg/kg body weight, twice a day for 10 days) led to clinical improvement of respiratory symptoms and radiographic improvement. This case highlights the significance of culture-based diagnostics and antimicrobial susceptibility testing in the management of multidrug-resistant co-infections in felines.
The Influence of Breed and Age Differences on Serum Testosterone Levels of Male Cats in Pekanbaru, Riau, Indonesia Mulya Fitranda; Rifia Tiara Fani; Tito Suprayoga; Triawan Alkausar; Frilianty Putri; Hadimas Bakti Pratama; Wiwin Suhandri; Indra Jaya; Bambang Saputra; Chairunnisa Filzah Abdina
Jurnal Sain Veteriner Vol 44, No 2 (2026): Agustus
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.113231

Abstract

This study aimed to investigate the influence of breed and age on serum testosterone concentrations in intact male cats. A total of thirty (n=30) clinically healthy, intact male cats of various breeds and age groups were recruited from privately owned households in Pekanbaru, Riau Province, Indonesia. Information on age and breed was obtained from structured owner questionnaires. Blood samples were collected aseptically from the jugular vein and processed to obtain serum, which was stored at –20°C until analysis. Serum testosterone concentrations were measured using the Enzyme-Linked Immunosorbent Assay (ELISA) method, and data were statistically analyzed using IBM SPSS Statistics software with a significance level of α = 0.05 (95% confidence interval). The study revealed a significant difference between age and serum testosterone levels. In contrast, no significant difference was found between breed and testosterone concentration. These findings provide preliminary reference data for future research in feline reproductive endocrinology and may serve as a foundation for assessing androgenic function in domestic cats.
Co-Authors Bambang Saputra Chairunnisa Filzah Abdina Frilianty Putri Hadimas Bakti Pratama Indra Jaya Mulya Fitranda Rifia Fani Rifia Tiara Fani Triawan Alkausar Wiwin Suhandri