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Aktivitas Antibakteri dan Formulasi Krim Dari Ekstrak Etanol Daun Kemangi (Ocimum basilicum L.) dan Daun Kari (Murraya koenigii L.) Safrina, Safrina; Novita, Eva; Mardhatillah, Mardhatillah; Syaddry, Alfi Yanna
Journal of Pharmaceutical and Health Research Vol 6 No 3 (2025): October 2025
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v6i3.8510

Abstract

The use of medicinal plants as active ingredients in topical formulations has been increasingly explored as a natural alternative to synthetic antimicrobial agents. This study aimed to formulate and evaluate a topical cream containing a combination of ethanolic extracts of curry leaves (Murraya koenigii L.) and basil leaves (Ocimum basilicum L.) as a natural antibacterial agent against Staphylococcus aureus. The extracts were prepared through maceration using 96% ethanol, followed by phytochemical screening and antibacterial testing using the well-diffusion method against Staphylococcus aureus ATCC 25923. Phytochemical analysis confirmed the presence of alkaloids, flavonoids, phenolics, saponins, and steroids in both extracts. The antibacterial assay showed that the 1:1 extract combination produced an average inhibition zone of 14.17 mm, classified as strong and exhibiting a partial synergistic effect compared with single extracts. Several oil-in-water (O/W) cream formulations were then developed to determine optimal physical stability. Formula F2 (2:1) demonstrated the best physical stability, with pH 6 ± 0.1, spreadability of ±5 cm, adhesion time >140 seconds, and viscosity of 4500–5000 cP, all meeting the SNI 16-4399-1996 standard. These findings indicate that the 1:1 combination ratio provides the highest antibacterial activity, while the 2:1 ratio yields the most stable physical characteristics, suggesting that both can serve as the basis for developing a safe, stable, and effective natural topical antibacterial cream against Staphylococcus aureus.
Effectiveness of the 5E Learning Cycle Model in Vocational Pharmaceutical Chemistry Learning: A Review Dwi Putri Rejeki; Fita Nelyza; Irma Zarwinda; Eva Novita
DIAJAR: Jurnal Pendidikan dan Pembelajaran Vol. 5 No. 1 (2026): Januari 2026
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/diajar.v5i1.6766

Abstract

This study is a systematic literature review aimed at analyzing the effectiveness of the Learning Cycle 5E instructional model in enhancing students’ conceptual understanding and scientific attitudes, while also examining its potential application in Pharmaceutical Chemistry learning at the vocational higher education level. This review addresses the growing need for active learning models that can bridge conceptual understanding with the practical competency demands of pharmaceutical education. The analysis employed a narrative synthesis approach, reviewing relevant research articles based on four main dimensions: learning context, research focus, research methodology, and reported key findings. The results indicate that the Learning Cycle 5E model consistently improves students’ conceptual understanding, reduces misconceptions, and fosters the development of scientific attitudes such as curiosity, responsibility, openness to evidence, and reflective thinking. In addition, several studies report that integrating the Learning Cycle 5E model with interactive learning technologies, including digital media and student-centered learning tools, enhances student motivation and active engagement in the learning process. Although most of the reviewed studies are situated within general chemistry education, the findings demonstrate strong relevance and high potential for application in Pharmaceutical Chemistry learning contexts. Therefore, this review recommends further implementation-based research in vocational higher education to strengthen empirical evidence and optimize the design of active, contextual, and reflective pharmaceutical learning.
Penentuan kalsium susu kambing segar dengan Spektrofotometri Serapan Atom (SSA) Safrina, Safrina; Adriani, Azmalina; Novita, Eva
Jurnal SAGO Gizi dan Kesehatan Vol 7, No 1 (2026): April
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v7i1.2686

Abstract

Background: Calcium (Ca) is an essential mineral abundantly present in goat milk and plays a crucial role in bone and dental development. Data on Ca levels in local goat milk from Banda Aceh remain limited, although such information is important for nutritional purposes and the development of livestock products. Atomic absorption spectrophotometry (AAS) is employed for mineral analysis owing to its high sensitivity and selectivity.Objective: This study aimed to determine the calcium content in fresh goat milk from three locations in Banda Aceh and Aceh Besar and to evaluate any differences between them.Methods: This was a descriptive quantitative research with an experimental laboratory approach conducted in Banda Aceh in 2025. Fresh goat milk samples were collected from Gampong Tibang (GT), Gampong Kopelma Darussalam (KD), and Gampong Lamblang Manyang (LM) in April 2025. The samples were digested with concentrated HNO₃ and analyzed using AAS at 422.7 nm. Data were statistically analyzed using one-way ANOVA.Results: The highest calcium content was found in KD (0.892 mg/L), followed by GT (0.856 mg/L), and the lowest in LM (0.582 mg/L). The overall mean calcium level was 0.777 mg/L. One-way ANOVA confirmed significant differences among locations (F = 61.62; p = 0.0001). Conclusion: Calcium levels in fresh goat milk varied significantly among locations and were potentially influenced by environmental factors, feeding practices, and goat physiology. These findings are expected to serve as a basis for developing high-quality local goat milk products and supporting the utilization of functional foods.
Pemberdayaan Masyarakat melalui Pemanfaatan Tanaman Obat Tradisional di Desa Krueng Dhoe Sanggeue Kecamatan Pidie Safrina, Safrina; Santi, Santi; Cut Suraiya Wahyuni Utami; Eva Novita
PaKMas: Jurnal Pengabdian Kepada Masyarakat Vol 6 No 1 (2026): Mei 2026
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/pakmas.v6i1.7421

Abstract

This community service activity aimed to strengthen community capacity through an integrated educational and participatory approach in Krueng Dhoe Sanggeue Village, Pidie District. The program involved counseling, hands-on training, and continuous mentoring, and was evaluated using a pre-test and post-test design. A total of 41 medicinal plant species were identified, primarily used to treat digestive disorders, hypertension, and cough. Leaves were the most utilized plant parts (35.5%), boiling was the dominant preparation method (31.70%), and oral consumption was the main mode of use (53.65%). Most plants were sourced from household gardens (43.90%), indicating strong local resource availability. The activity resulted in a significant improvement in community knowledge regarding the proper utilization of medicinal plants. However, challenges remain in dosage standardization, safety, and processing techniques. Therefore, sustained training and structured assistance are necessary to ensure safe utilization and to optimize the health and economic potential of medicinal plant use.