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UJI STABILITAS FORMULASI FACE TONER EKSTRAK DAUN PEGAGAN (Centella asiatica) DENGAN VARIASI KONSENTRASI GLISERIN Rumanis Afifah; Gigih Kenanga Sari; Maulita Saraswati
Joseph: Journal of Science and Pharmacy Vol 5 No 1 (2025): Journal of Science and Pharmacy (Joseph)
Publisher : Universitas An Nuur

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Abstract

Background: The cosmetics industry continues to grow with increasing interest in natural ingredients. Gotu kola leaves (Centella Asiatica) contain bioactive compounds with antioxidant, anti-inflammatory, and skin repair effects, making them potential ingredients for face toners. Toners refresh and balance the skin's pH, while glycerin acts as a humectant to maintain moisture, but its concentration affects the stability and comfort of the preparation. This study formulated a gotu kola extract face toner with varying glycerin concentrations and evaluated its stability through a cycling test (±4 °C and ±40 °C, six cycles). This test is important for assessing the physical and chemical quality of the product while meeting cosmetic registration requirements. Purpose: 1.To determine the compounds contained in gotu kola leaf extract (Centella Asiatica). 2. To determine whether there is an effect on physical quality and stability in variations of glycerin in gotu kola leaf extract (Centella Asiatica) face toner formulations. 3. To determine the face toner formulation that has good stability with variations in glycerin concentration.. Method: Pegagan leaves (Centella asiatica) were extracted using the maceration method with 70% ethanol solvent.   The extract obtained was subjected to phytochemical testing and TLC testing, followed by the preparation of formulations according to the predetermined formulation. A cycling test was conducted for 12 days with 6 cycles, followed by physical quality testing of the face toner formulation.Results: Pegagan extract compounds contain alkaloids, flavonoids, and tannins. There were no significant differences between formulations 1, 2, and 3 with variations in humectants (glycerin). Formulation F2 showed the most optimal stability because both viscosity and pH were relatively stable during six storage cycles. Conclusion: Based on this study, it was found that face toner preparations containing gotu kola leaf extract (Centella Asiatica) at concentrations of 2%, 4%, and 6% had fairly good physical stability parameters.
PENGARUH VARIASI KONSENTRASI TRIETHANOLAMINE TERHADAP STABILITAS FISIK LOTION EKSTRAK DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb.) Yulia Rika Femina; Gigih Kenanga Sari; Maulita Saraswati
Joseph: Journal of Science and Pharmacy Vol 5 No 1 (2025): Journal of Science and Pharmacy (Joseph)
Publisher : Universitas An Nuur

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Abstract

Background: Fragrant pandan leaves (Pandanus amaryllifolius Roxb.) are known to contain various secondary metabolites such as alkaloids, flavonoids, tannins, saponins, and terpenoids, making them potentially useful as ingredients in herbal cosmetic formulations, especially lotions. Triethanolamine acts as an emulsion stabilizer for oil-in-water (O/W) emulsions. Variations in triethanolamine concentration are expected to affect the physical stability of the lotion, thus further research is needed to optimize the formulation. Purpose: This study aims to evaluate the effect of triethanolamine concentration on the physical stability of formulated pandan leaf lotion, and to determine the triethanolamine concentration that is most stable and effective. Method: Fragrant pandan leaves were extracted with ethanol through maceration. The lotion preparation consisted of 4 formulations with different concentrations of triethanolamine (0%, 2.5%, 3%, and 3.5%). Physical stability was evaluated through organoleptic tests, homogeneity, pH, viscosity, spreadability, adhesiveness, and type of emulsion under room temperature, cooling, and storage conditions for 6 cycles. The data were analyzed using ANOVA, if the data were not normal, the Kruskal–Wallis test was used. Results: The preparation of lotion from the extract of fragrant pandan leaves (Pandanus amaryllifolius Roxb.) in formula 0, formula I, formula II, and formula III has physical characteristics and stability that comply with SNI standards Conclusion: The lotion preparation with 3.5% triethanolamine concentration shows the most stable lotion properties compared to formulation 0, I, and formula II.
Uji Stabilitas Fisik Facial Wash Gel Ekstrak Daun Mengkudu (Morinda citrifolia L.) Dengan Variasi Carbopolol Sebagai Gelling Agent Eva Natalia; Maulita Saraswati; Supriyanto
Joseph: Journal of Science and Pharmacy Vol 5 No 1 (2025): Journal of Science and Pharmacy (Joseph)
Publisher : Universitas An Nuur

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Abstract

Background: Noni leaves (Morinda citrifolia L.) are a plant with antibacterial properties. One of the most commonly used antibacterial cosmetic preparations is facial wash gel. Purpose: This study aims to formulate a facial wash gel preparation containing noni leaf extract (Morinda citrifolia L.) which has antibacterial content with variations of carbopolol.. Method: Noni leaf extract (Morinda citrifolia L.) was macerated with 96% ethanol solvent and tested for specific parameters in the form of organoleptic, ethanol-free, phyrochemical screening, and Thin Layer Chromatography tests and non-specific parameters in the form of drying loss. Then tested for physical quality, organoleptic test, homogeneity, pH, foam stability, viscosity, adhesive power. Then tested for physical stability for 6 cycles with 2 temperatures, 4 ° Celsius and 40 ° Celsius. with carbopolol concentrations of 0.5%, 1%, 1.5%, and 2%. Results: The research results showed that noni leaf extract can be used as a facial wash gel and contains flavonoids, alkaloids, terpenoids, and saponins. The noni leaf extract (Morinda citrifolia L.) facial wash gel produced good quality and physical stability. The best facial wash gel was formula three (2% carbopolol concentration). Conclusion: Noni leaf extract (Morinda citrifolia L.) can be made into a facial wash gel with good quality and physical stability and produces the best facial wash gel formula in the FIII preparation (2% carbopolol concentration).
ANALISIS NATRIUM SIKLAMAT PADA TEH JUMBO DI KABUPATEN GROBOGAN DENGAN METODE KUALITATIF DAN KUANTITATIF iman cahyani_putri; Maulita Saraswati; Wahyu Purwanjani
Joseph: Journal of Science and Pharmacy Vol 5 No 1 (2025): Journal of Science and Pharmacy (Joseph)
Publisher : Universitas An Nuur

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Abstract

Background: Jumbo tea is a popular drink because it is practical and affordable. However, manufacturers often add sodium cyclamate, an artificial sweetener that is 30 times as sweet as sucrose and is known to be cheap, to reduce production costs. Excessive use of sodium cyclamate can cause health problems. Purpose: This research aims to analyze the presence and levels of sodium cyclamate in jumbo tea drinks circulating in Grobogan Regency. Method: This research used 10 jumbo tea samples taken from 5 sub-districts in Grobogan Regency using a purposive sampling method, namely samples that had an excessively sweet taste. Analysis was carried out qualitatively using the deposition method and quantitatively using the UV-Vis Spectrophotometry method. Results: Of the 10 samples tested, the qualitative test results showed that 3 samples were positive for containing sodium cyclamate (samples C2, E1, and E2) which were characterized by the formation of a white precipitate. The quantitative test results on the three positive samples showed the following sodium cyclamate levels: sample C2 was 0.08104 g/kg, sample E1 was 0.04693 g/kg, and sample E2 was 0.06242 g/kg. Conclusion: There were 3 out of 10 jumbo tea samples in Grobogan Regency that tested positive for sodium cyclamate15. However, the sodium cyclamate levels found in the three samples were still below the maximum limit permitted by BPOM (3 g/kg).