Jurnal Biologi Tropis
Vol. 24 No. 3 (2024): July - September

Resveratrol: A Potential Active Compound for Inflammatory Bowel Disease

Saraswati, Ni Wayan Citra Ayu (Unknown)
Nugraha, Gede Rama Hardy (Unknown)
Retnaningsih, Ekawaty (Unknown)
Afifah, Fiza (Unknown)
Firdaus, Silmi (Unknown)
Mutia, Baiq Marceliya Anjani (Unknown)
Mukhlishah, Neneng Rachmalia Izzatul (Unknown)



Article Info

Publish Date
25 Jul 2024

Abstract

Inflammatory Bowel Disease (IBD) is a chronic intestinal disorder consisting of Crohn’s Disease (CD) and Ulcerative Colitis (UC). The highest prevalence of IBD is found in Asia and the cases often occur in the 15-35 group of age. Conventional therapy options that are commonly used have some side effects that impact IBD patients. Therefore, it is necessary to look for new strategies in order to treat IBD regarding their effectiveness, affordability and achieving minimum side effects. Resveratrol, a natural non-flavonoid polyphenolic compound, is commonly found in grapes and various types of berries. It is known to potentially overcome inflammation in IBD through various mechanisms including acting as anti-inflammatory, antioxidant, immunomodulatory effects, and its ability to influence the gut microbiota. This study is aiming for explaining and reviewing further mainly on resveratrol’s extraction method and its mechanism of actions to improve IBD. The resources for this study are done by searching through PubMed, ProQuest, ScienceDirect, MDPI, and Google Scholar with keywords (Inflammatory Bowel Disease) AND (Resveratrol), ⁠(Incidence and Prevalence) of Inflammatory Bowel Disease across Asia, (Threat) AND (Therapy) AND (Inflammatory Bowel Disease), (Bioactive) AND (Therapy) AND (Inflammatory Bowel Disease), (Extraction) AND (Method) AND (Resveratrol), and (Pathophysiology) AND (Inflammatory Bowel Disease). Based on evidence found on resveratrol’s benefits, this compound is apparently promising to alternatively treat IBD, but still needs more research to support its effectiveness.

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Journal Info

Abbrev

JBT

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

Description

Jurnal Biologi Tropis (ISSN Cetak 1411-9587 dan ISSN Online 2549-7863) diterbitkan mulai tahun 2000 dengan frekuensi 2 kali setahun oleh Program Studi Pendidikan Biologi PMIPA FKIP Universitas Mataram, berisi hasil penelitian dan ulasan Ilmiah dalam bidang Biologi ...