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All Journal Jurnal Sains Teknologi dan Lingkungan (JSTL) Jurnal Biologi Tropis TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora
Nugraha, Gede Rama Hardy
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Engineering Immunology & microbiology Public Health Other

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Iskemia Tungkai Akut: Perspektif Baru pada Diagnosis, Pengobatan, dan Upaya Pencegahan Amputasi Balqis, Fathinnisa Adillah; Ermawan, Romi; Nugraha, Gede Rama Hardy; Ragad, Putra; Dewi, Komang Puspa; Ramadhani, Dhea Asty; Rizky, Muhammad Ilham
TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Vol 5, No 4 (2024)
Publisher : Universitas Nurul Jadid

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33650/trilogi.v5i4.9796

Abstract

Acute Limb Ischemia (ALI) is a medical emergency caused by a sudden decrease in blood flow to the extremities, often within less than two weeks. This review examines the definition, epidemiology, pathophysiology, clinical presentation, and management of ALI. The condition is primarily triggered by thrombosis or embolism in arteries previously affected by atherosclerosis. Characteristic symptoms include the "6 Ps": pain, paresthesia, poikilothermia, paralysis, pulselessness, and pallor. Diagnosis involves a combination of medical history, physical examination, and imaging, particularly Doppler ultrasound. Management strategies focus on prompt revascularization using catheter-directed thrombolysis, open embolectomy, or percutaneous mechanical thrombectomy. The Rutherford classification is employed to assess severity and guide treatment plans. Timely and effective intervention significantly improves patient outcomes, minimizes the risk of major amputation, and preserves limb function. This study emphasizes the importance of multidisciplinary collaboration in ALI management to optimize prognosis.
Terapi Saat Ini untuk Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): Sebuah Literature Review Hunaifi, Ilsa Hunaifi; Wicaksono, Teguh Budi; Nugraha, Gede Rama Hardy; Maulida, Rizka Ayu; Kusumadewi, Rima Cahyati; Pratiwi, Rukmanggana Satya; Amaliya, Annisa Risqi; Sepestian, Ghina Shadrina Rienti
JURNAL SAINS TEKNOLOGI & LINGKUNGAN Vol. 10 No. 3 (2024): JURNAL SAINS TEKNOLOGI & LINGKUNGAN
Publisher : LPPM Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jstl.v10i3.619

Abstract

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune disease. The European Academy of Neurology recommends treatment using corticosteroids, immunoglobulin, plasma exchange, & other treatments as treatment options for chronic inflammatory demyelinating polyradiculoneuropathy. However, several studies in recent years have shown that there is potential in the treatment of chronic inflammatory demyelinating Polyradiculoneuropathy. The aim of this literature review is to provide the latest therapy for chronic inflammatory demyelinating polyradiculoneuropathy based on guidelines as well as other information therapy alternatives. The method used in this literature review uses searches in several databases. The results of several studies show the development of chronic inflammatory demyelinating polyradiculoneuropathy therapy both pharmacologically & non-pharmacologically. The development of therapy for chronic inflammatory demyelinating polyradiculoneuropathy, namely hematopoietic stem cells & spinal cord stimulation, shows potential as a therapeutic option for patients with chronic inflammatory demyelinating polyradiculoneuropathy.
Resveratrol: A Potential Active Compound for Inflammatory Bowel Disease Saraswati, Ni Wayan Citra Ayu; Nugraha, Gede Rama Hardy; Retnaningsih, Ekawaty; Afifah, Fiza; Firdaus, Silmi; Mutia, Baiq Marceliya Anjani; Mukhlishah, Neneng Rachmalia Izzatul
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7303

Abstract

Inflammatory Bowel Disease (IBD) is a chronic intestinal disorder consisting of Crohn’s Disease (CD) and Ulcerative Colitis (UC). The highest prevalence of IBD is found in Asia and the cases often occur in the 15-35 group of age. Conventional therapy options that are commonly used have some side effects that impact IBD patients. Therefore, it is necessary to look for new strategies in order to treat IBD regarding their effectiveness, affordability and achieving minimum side effects. Resveratrol, a natural non-flavonoid polyphenolic compound, is commonly found in grapes and various types of berries. It is known to potentially overcome inflammation in IBD through various mechanisms including acting as anti-inflammatory, antioxidant, immunomodulatory effects, and its ability to influence the gut microbiota. This study is aiming for explaining and reviewing further mainly on resveratrol’s extraction method and its mechanism of actions to improve IBD. The resources for this study are done by searching through PubMed, ProQuest, ScienceDirect, MDPI, and Google Scholar with keywords (Inflammatory Bowel Disease) AND (Resveratrol), ⁠(Incidence and Prevalence) of Inflammatory Bowel Disease across Asia, (Threat) AND (Therapy) AND (Inflammatory Bowel Disease), (Bioactive) AND (Therapy) AND (Inflammatory Bowel Disease), (Extraction) AND (Method) AND (Resveratrol), and (Pathophysiology) AND (Inflammatory Bowel Disease). Based on evidence found on resveratrol’s benefits, this compound is apparently promising to alternatively treat IBD, but still needs more research to support its effectiveness.
Current Therapies for Chronic Inflammatory Demyelinating Polyradiculoneuropathy: A Literature Review Wicaksono, Teguh Budi; Nugraha, Gede Rama Hardy; Maulida, Rizka Ayu; Kusumadewi, Rima Cahyati; Pratiwi, Rukmanggana Satya; Amaliya, Annisa Risqi; Sepestian, Ghina Shadrina Rienti; Hunaifi, Ilsa
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7395

Abstract

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune disease. The European Academy of Neurology recommends treatment using corticosteroids, immunoglobulin, plasma exchange, & other treatments as treatment options for chronic inflammatory demyelinating polyradiculoneuropathy. However, several studies in recent years have shown that there is potential in the treatment of chronic inflammatory demyelinating Polyradiculoneuropathy. The aim of this literature review is to provide the latest therapy for chronic inflammatory demyelinating polyradiculoneuropathy based on guidelines as well as other information therapy alternatives. The method used in this literature review uses searches in several databases. The results of several studies show the development of chronic inflammatory demyelinating polyradiculoneuropathy therapy both pharmacologically & non-pharmacologically. The development of therapy for chronic inflammatory demyelinating polyradiculoneuropathy, namely hematopoietic stem cells & spinal cord stimulation, shows potential as a therapeutic option for patients with chronic inflammatory demyelinating polyradiculoneuropathy.
Co-Authors Afifah, Fiza Amaliya, Annisa Risqi Balqis, Fathinnisa Adillah Dewi, Komang Puspa Firdaus, Silmi Hunaifi, Ilsa Hunaifi Ilsa Hunaifi, Ilsa Kusumadewi, Rima Cahyati Maulida, Rizka Ayu Mukhlishah, Neneng Rachmalia Izzatul Mutia, Baiq Marceliya Anjani Pratiwi, Rukmanggana Satya Ragad, Putra Ramadhani, Dhea Asty Retnaningsih, Ekawaty Rizky, Muhammad Ilham Romi Ermawan, Romi Saraswati, Ni Wayan Citra Ayu Sepestian, Ghina Shadrina Rienti Teguh Budi Wicaksono