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All Journal Jurnal Biologi Tropis Promotor: Jurnal Mahasiswa Kesehatan Masyarakat
Afifah, Fiza
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Nursing Public Health Other

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Efusi Pleura: Literature Review Supriantarini, Dita; Afifah, Fiza
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.8948

Abstract

Pleural effusion is an abnormal accumulation of fluid in the pleural space, which is the thin cavity between the pleural layers that surround the lungs. Globally, around 1.5 million patients are diagnosed each year, with the main causes being congestive heart failure, malignancy, and infection. The purpose of this article is to determine pleural effusion: a literature study. The method used is a literature review using several database journals taken from Google Scholar. Relevant keywords related to the title of the article are used in the search strategy. The results of the literature study obtained that pleural effusion is classified into transudate and exudate. The diagnosis of pleural effusion is made through anamnesis and physical examination. In addition, there are supporting examinations consisting of chest x-ray, chest ultrasound, chest CT scan, and pleural fluid analysis. Management in dealing with pleural effusion through pleural puncture (thoracentesis), thoracoscopy, conservative management (if the fluid is small), installation of water seal drainage, pleurodesis, complications and prognosis. In conclusion, pleural effusion can be diagnosed in 2 ways and by carrying out other supporting examinations.
Getting to Know More about Tetanus Faqih, Fauzan; Aritiah, M. Awalul Rizky; Solihatin, Illiyani; Afifah, Fiza; Faranajhia, Hagia; Wicaksono, Teguh Budi; Irmayanto, Tomi
PROMOTOR Vol. 8 No. 3 (2025): JUNI
Publisher : Universitas Ibn Khaldun Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/pro.v8i3.1188

Abstract

Tetanus is an acute disease that affects the central nervous system caused by tetanospasmin toxin produced by Clostridium tetani. Tetanus is a deadly disease in developing countries, killing approximately 500,000 people per year. This is due to lack of hygiene, easy contamination, poor wound care, lack of public awareness of the importance of hygiene and tetanus vaccination. In general, tetanus is characterized by rigidity, muscle spasm and autonomic disorders. Spasms almost always occur in the neck and jaw muscles causing jaw closure (trismus, lockjaw) and involve not only the extremity muscles, but also the trunk muscles. Tetanus is not transmitted from human to human and can be prevented through immunization. Clostridium tetani is quite widespread in nature and cannot be eradicated. To reduce the number of cases, tetanus treatment efforts focus on prevention using vaccination with active immunization or passive immunization and post-exposure care.
Resveratrol: A Potential Active Compound for Inflammatory Bowel Disease Saraswati, Ni Wayan Citra Ayu; Nugraha, Gede Rama Hardy; Retnaningsih, Ekawaty; Afifah, Fiza; Firdaus, Silmi; Mutia, Baiq Marceliya Anjani; Mukhlishah, Neneng Rachmalia Izzatul
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7303

Abstract

Inflammatory Bowel Disease (IBD) is a chronic intestinal disorder consisting of Crohn’s Disease (CD) and Ulcerative Colitis (UC). The highest prevalence of IBD is found in Asia and the cases often occur in the 15-35 group of age. Conventional therapy options that are commonly used have some side effects that impact IBD patients. Therefore, it is necessary to look for new strategies in order to treat IBD regarding their effectiveness, affordability and achieving minimum side effects. Resveratrol, a natural non-flavonoid polyphenolic compound, is commonly found in grapes and various types of berries. It is known to potentially overcome inflammation in IBD through various mechanisms including acting as anti-inflammatory, antioxidant, immunomodulatory effects, and its ability to influence the gut microbiota. This study is aiming for explaining and reviewing further mainly on resveratrol’s extraction method and its mechanism of actions to improve IBD. The resources for this study are done by searching through PubMed, ProQuest, ScienceDirect, MDPI, and Google Scholar with keywords (Inflammatory Bowel Disease) AND (Resveratrol), ⁠(Incidence and Prevalence) of Inflammatory Bowel Disease across Asia, (Threat) AND (Therapy) AND (Inflammatory Bowel Disease), (Bioactive) AND (Therapy) AND (Inflammatory Bowel Disease), (Extraction) AND (Method) AND (Resveratrol), and (Pathophysiology) AND (Inflammatory Bowel Disease). Based on evidence found on resveratrol’s benefits, this compound is apparently promising to alternatively treat IBD, but still needs more research to support its effectiveness.
Cerebral Palsy : A Literatur Review Afifah, Fiza; Lale Nandita Hulfifa; Baiq Annisa Salmaadani Syafitri; Carolina Janicca Winda Manafe; Zhafirah Amany; Zirly Vera Aziri; Syahla Marsellita Wahyudi; Anak Agung Bagus Tito Indra Prawira Negara; Muhammad Abdurrosyid; Muhammad Azim Billah; Dinie Ramdhani Kusuma
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7518

Abstract

Cerebral Palsy is a non-progressive damage that occurs in the brain tissue of a fetus or infant during development. CP is a disease that occurs worldwide, with approximately 1 to 4 children out of 1,000 live births having CP in population study data covering the entire world. CP is one of the most common causes of motor disability in children. Prompt diagnosis and appropriate treatment can promote a better prognosis for the patient. The writing of this article aims to add information related to CP so that early detection can be done and how CP therapy can improve the quality of life of people with CP. The research method used is a type of literature review that discusses the definition, etiology, epidemiology, pathophysiology, how to diagnose to management of cerebral palsy. Data sources were retrieved by conducting electronic searches through library search sites including PubMed, ProQuest, ScienceDirect, MDPI and Google Scholar.
Necrotizing Enterocolitis: Stem Cell as Future Potential Therapy Syafitri, Bq. Annisa Salmaadani; Manafe, Carolina Janicca Winda; Hulfifa, Lale Nandita; Aziri, Zirly Vera; Afifah, Fiza; Wahyudi, Syahla Marsellita; Musyarof, Disa Fadil
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7529

Abstract

Necrotizing enterocolitis (NEC) is an inflammatory bowel condition in infants and considered as one of the leading causes of death in infants, especially premature infants. The high mortality rate due to NEC in recent decades has become a problem because there is no current therapy that can optimally treat NEC. Currently, NEC is treated using Bell's Staging as a guide and surgery is a common procedure, especially if necrosis has occurred. However, complications arising from surgery not only reduce the patient's quality of life but can also result in death. Therefore, it is necessary to find new therapy in order to treat NEC effectively and minimize the possibility of side effects in NEC patients. Stem cells are known for their regenerative abilities which is potential to overcome tissue damage due to excessive inflammation in NEC. Previous studies also show that stem cells have become new therapy to treat other intestinal diseases which have similar features with NEC. This study aims to explain mainly on stem cells’s promising mechanism of action in treating NEC. The method used for this study is a literature review design by selecting and reviewing relevant previous literature using databases such as Google Scholar, PubMed and Science Direct. This paper summarizes pathophysiology, clinical manifestation, current therapy and mechanism of action of stem cells and their derivatives as future potential therapy for NEC. Based on evidence found, stem cells and their derivatives are potential to be used as NEC therapy in the future. However, the data obtained is not sufficient to support its use in humans. Given the urgency in finding an effective NEC management and the potency of stem cells, further research is needed to support the use of stem cells as NEC therapy.
Diabetic Retinopathy: A Literature Review Maulida, Rizka Ayu; Afifah, Fiza
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7589

Abstract

Diabetic retinopathy is a complication of diabetes mellitus characterized by visual impairment and potentially blindness. This literature review aims to enhance knowledge about diabetic retinopathy. Sources for this review were gathered through online databases and include review articles, research studies, and professional guidebooks related to the topic. Hyperglycemic conditions associated with diabetes mellitus trigger angiogenesis and inflammatory pathways, leading to diabetic retinopathy. The condition is classified into two types: non-proliferative diabetic retinopathy and proliferative diabetic retinopathy, with management strategies varying depending on the type. As the prevalence of diabetes mellitus increases, so does the expected incidence of diabetic retinopathy, highlighting the need for effective prevention strategies, which include both primary and secondary prevention.
Co-Authors Anak Agung Bagus Tito Indra Prawira Negara Aritiah, M. Awalul Rizky Aziri, Zirly Vera Baiq Annisa Salmaadani Syafitri Carolina Janicca Winda Manafe Dinie Ramdhani Kusuma Faqih, Fauzan Faranajhia, Hagia Firdaus, Silmi Hulfifa, Lale Nandita Irmayanto, Tomi Lale Nandita Hulfifa Manafe, Carolina Janicca Winda Maulida, Rizka Ayu Muhammad Abdurrosyid Muhammad Azim Billah Mukhlishah, Neneng Rachmalia Izzatul Musyarof, Disa Fadil Mutia, Baiq Marceliya Anjani Nugraha, Gede Rama Hardy Retnaningsih, Ekawaty Saraswati, Ni Wayan Citra Ayu Solihatin, Illiyani Supriantarini, Dita Syafitri, Bq. Annisa Salmaadani Syahla Marsellita Wahyudi Teguh Budi Wicaksono Wahyudi, Syahla Marsellita Zhafirah Amany Zirly Vera Aziri