Jurnal Aisyah : Jurnal Ilmu Kesehatan
Vol 10, No 1 (2025): March

SERUM METALLOPRETEINASE 3 (MMP-3) LEVELS IN LUNG CANCER AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) PATIENTS

Soemarwoto, Retno Ariza (Unknown)
Mustofa, Syazili (Unknown)
Suwarno, Sukarti San (Unknown)
Yunus, Faisal (Unknown)
Listiandoko, Raden Dicky Wirawan (Unknown)
Sinaga, Fransisca TY (Unknown)
Febrihartati, Isura (Unknown)



Article Info

Publish Date
30 Mar 2025

Abstract

Chronic Obstructive Pulmonary Disease (COPD) and Lung Cancer are among the diseases with high mortality rates and a similar genetic disposition. COPD is known to be a significant risk factor for lung cancer. Matrix metalloproteinase-3 (MMP-3) is a protein that plays a role in the growth stage of cancer that has the potential to develop COPD into lung cancer. This descriptive observational study aimed to compare plasma MMP-3 levels among four groups: healthy individuals, lung cancer patients, COPD patients, and patients with both lung cancer and COPD. The findings revealed that plasma MMP-3 levels were lowest in the healthy group and higher in the other groups. The increase in plasma MMP-3 levels among pathological subjects suggests a potential association between serum MMP-3 levels and the development of lung cancer in COPD patients. However, further research is needed to clarify this relationship.

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Journal Info

Abbrev

jika

Publisher

Subject

Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Description

Jurnal Aisyah: Jurnal Ilmu Kesehatan (JIKA), with registered number ISSN 2502-4825 (Print) and ISSN 2502-9495 (Online), is an international peer-reviewed journal published two times a year (June and December) by Universitas Aisyah Pringsewu (UAP) Lampung. JIKA is intended to be the journal for ...