Journal of Pharmaceutical Care and Sciences
Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)

F Formulasi Dan Evaluasi Sediaan Serum Gel Ekstrak Gliserin Bunga Asoka (Ixora coccinea L.)

Rianti, Nur Addina (Unknown)
Audina, Mia (Unknown)
Muzdalifah, Nur (Unknown)
Ramadhan, Novalina Rossa (Unknown)
Donaretsi, Olga Nathania (Unknown)
Laili, Rofiatul (Unknown)



Article Info

Publish Date
30 Jun 2025

Abstract

Background:  The most common causes of skin dryness and redness are free radicals, pollution and ultraviolet rays. Cosmetics are epidermal treatments to nourish the body. One of the emerging cosmetics is a serum gel preparation that can maintain elasticity and moisturize the skin. While one of the plants has the potential to be used as a safe active ingredient in cosmetics, namely the asoka flower plant (Ixora coccinea L.) which is rich in phytochemical compounds, such as flavonoids, saponins, tannins, alkaloids, glycosides, terpenoids and carbohydrates, so it has very strong antioxidant activity. Objective:  To determine the appropriate formulation of asoka flower extract serum gel preparation and the effect of varying the concentration of asoka flower glycerin extract on the physical evaluation of serum gel preparation. Methods: This study used an experimental approach method with a true experimental design. The serum gel preparation was divided into 2 treatments with 15% and 30% concentration of active ingredients. The optimal formulation of the preparation is adjusted to the evaluation results and requirements set. Results:  Formula I met the organoleptical evaluation criteria, pH, flow type, and adhesion, but did not meet the specifications for viscosity and spreadability. While formula II meets the specifications of organoleptical test, pH, viscosity, flow type, adhesion, and spreadability. Conclusion:  From the evaluation conducted, it was found that the most optimal formula was formula II with 30% extract concentration.  Based on statistical tests using the Mann-Whitney Test, there is no effect on variations in the concentration of asoka flower extract.

Copyrights © 2025






Journal Info

Abbrev

jpcs

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

Description

Journal of Pharmaceutical Care and Sciences published by the LPPM Sari Mulia UniversityPharmacy department of Sari Mulia University offers a forum for publishing the original research related to pharmaceutical science and clinical research. our focus and scope are Pharmaceutical Technology, ...