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Rianti, Nur Addina
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Literature Review: Efektivitas Ekstrak Asam Jawa (Tamarindus indica) Sebagai Terapi Dismenore Terhadap Penurunan Instensitas Nyeri Haid: Literature Review: Effectiveness of Tamarind Extract (Tamarindus indicia) as Dimenore Theraphy on Reduction of Haid Pain Intensity Rohama, Rohama; Rianti, Nur Addina; Octavia, Mutia; Fuaddah, Munawarah; Yanti, Novita
Jurnal Surya Medika (JSM) Vol. 11 No. 2 (2025): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v11i2.10034

Abstract

Dismenore adalah kondisi nyeri haid yang umum dialami oleh perempuan usia reproduktif, dengan prevalensi mencapai 65,4% di Indonesia. Terdapat dua jenis dismenore, yaitu dismenore primer dan sekunder. Penanganan dismenore primer umumnya dilakukan dengan obat antiinflamasi nonsteroid (OAINS), namun penggunaan jangka panjang dapat menimbulkan efek samping. Oleh karena itu, diperlukan pengobatan alternatif yang lebih aman, salah satunya adalah ekstrak asam jawa ( Tamarindus indica ) yang diketahui mengandung senyawa bioaktif dengan efek antiinflamasi dan analgesik. Penelitian ini bertujuan untuk meninjau efektivitas ekstrak buah asam jawa dalam menurunkan intensitas nyeri haid pada penderita dismenore melalui analisis literatur. Metode yang digunakan adalah Systematic Literature Review (SLR) dengan mengumpulkan dan menganalisis artikel yang relevan dari database Google Scholar. Hasil kajian menunjukkan bahwa ekstrak asam jawa mengandung senyawa bioaktif seperti tanin, saponin, flavonoid, dan polifenol, yang berkontribusi pada efek antiinflamasi dan analgesik. Selain itu, berdasarkan kajian klinis, asam jawa efektif dalam mengurangi nyeri dismenore, dengan mekanisme kerja yang melibatkan penghambatan produksi prostaglandin dan peningkatan aliran darah ke rahim. Penelitian ini diharapkan dapat menjadi dasar ilmiah untuk pengembangan terapi berbasis fitofarmaka yang aman dan berkelanjutan dalam penatalaksanaan dismenore primer.
F Formulasi Dan Evaluasi Sediaan Serum Gel Ekstrak Gliserin Bunga Asoka (Ixora coccinea L.) Rianti, Nur Addina; Audina, Mia; Muzdalifah, Nur; Ramadhan, Novalina Rossa; Donaretsi, Olga Nathania; Laili, Rofiatul
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.780

Abstract

Background:  The most common causes of skin dryness and redness are free radicals, pollution and ultraviolet rays. Cosmetics are epidermal treatments to nourish the body. One of the emerging cosmetics is a serum gel preparation that can maintain elasticity and moisturize the skin. While one of the plants has the potential to be used as a safe active ingredient in cosmetics, namely the asoka flower plant (Ixora coccinea L.) which is rich in phytochemical compounds, such as flavonoids, saponins, tannins, alkaloids, glycosides, terpenoids and carbohydrates, so it has very strong antioxidant activity. Objective:  To determine the appropriate formulation of asoka flower extract serum gel preparation and the effect of varying the concentration of asoka flower glycerin extract on the physical evaluation of serum gel preparation. Methods: This study used an experimental approach method with a true experimental design. The serum gel preparation was divided into 2 treatments with 15% and 30% concentration of active ingredients. The optimal formulation of the preparation is adjusted to the evaluation results and requirements set. Results:  Formula I met the organoleptical evaluation criteria, pH, flow type, and adhesion, but did not meet the specifications for viscosity and spreadability. While formula II meets the specifications of organoleptical test, pH, viscosity, flow type, adhesion, and spreadability. Conclusion:  From the evaluation conducted, it was found that the most optimal formula was formula II with 30% extract concentration.  Based on statistical tests using the Mann-Whitney Test, there is no effect on variations in the concentration of asoka flower extract.
Co-Authors Donaretsi, Olga Nathania Fuaddah, Munawarah Laili, Rofiatul Mia Audina, Mia Muzdalifah, Nur Octavia, Mutia Ramadhan, Novalina Rossa Rohama, Rohama Yanti, Novita