Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Vol. 4 No. 4 (2026): Juli : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan

Integrasi Parameter Spesifik, Nonspesifik, dan Penapisan Fitokimia Sebagai Sidik Mutu Ekstrak n-Heksana Daun Begonia × erythrophylla Herincq

Lia Fikayuniar (Universitas Buana Perjuangan Karawang)
Putri Agustina (Universitas Buana Perjuangan Karawang)
Farhamzah Farhamzah (Universitas Buana Perjuangan Karawang)
Delika Syalomita (Universitas Buana Perjuangan Karawang)
Diany Astuti (Universitas Buana Perjuangan Karawang)



Article Info

Publish Date
30 Jul 2026

Abstract

Begonia × erythrophylla Herincq is an ornamental plant with potential as a source of secondary metabolites; however, information on the standardization of its non-polar extract remains limited. This study aimed to establish the quality profile of the n-hexane extract of Begonia × erythrophylla Herincq  leaves based on specific and non-specific parameters and phytochemical screening. An experimental study was conducted using successive maceration of 317 g of powdered leaves. The extract was evaluated for yield, organoleptic properties, water- and ethanol-soluble extractive values, loss on drying, specific gravity, ash values, and secondary metabolite groups. Extraction produced 37.0 g of extract with a yield of 11.67%. The extract was thick, dark green, homogeneous, and had a characteristic odor. Phytochemical screening indicated the presence of alkaloids, flavonoids, tannins, polyphenols, steroids, and monoterpenoids/sesquiterpenoids, whereas quinones and saponins were not detected. The water- and ethanol-soluble extractive values were 0.1137 ± 0.0401% and 0.2119 ± 0.0095%, respectively. Loss on drying was 0.0106 ± 0.0017%, specific gravity was 0.8802 ± 0.0029 g/mL, total ash was 0.5543 ± 0.0434%, water-soluble ash was 0.4859 ± 0.0405%, and acid-insoluble ash was 0.4845 ± 0.0229%. Overall, the ethanol-soluble extractive value, loss on drying, specific gravity, and ash parameters were relatively consistent, whereas the water-soluble extractive value showed considerable variation. These findings provide a preliminary standardization profile for the n-hexane extract of Begonia × erythrophylla Herincq leaves. However, the water-soluble extractive value and relationships among ash parameters require verification before being established as quality specifications for herbal raw materials.

Copyrights © 2026






Journal Info

Abbrev

OBAT

Publisher

Subject

Health Professions Nursing Public Health

Description

Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan ...