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All Journal Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Jurnal Pengabdian Kepada Masyarakat
Diany Astuti
Universitas Buana Perjuangan Karawang
Economics, Econometrics & Finance Education Engineering Health Professions Nursing Public Health Social Sciences

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Integrasi Parameter Spesifik, Nonspesifik, dan Penapisan Fitokimia Sebagai Sidik Mutu Ekstrak n-Heksana Daun Begonia × erythrophylla Herincq Lia Fikayuniar; Putri Agustina; Farhamzah Farhamzah; Delika Syalomita; Diany Astuti
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 4 (2026): Juli : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i4.2405

Abstract

Begonia × erythrophylla Herincq is an ornamental plant with potential as a source of secondary metabolites; however, information on the standardization of its non-polar extract remains limited. This study aimed to establish the quality profile of the n-hexane extract of Begonia × erythrophylla Herincq  leaves based on specific and non-specific parameters and phytochemical screening. An experimental study was conducted using successive maceration of 317 g of powdered leaves. The extract was evaluated for yield, organoleptic properties, water- and ethanol-soluble extractive values, loss on drying, specific gravity, ash values, and secondary metabolite groups. Extraction produced 37.0 g of extract with a yield of 11.67%. The extract was thick, dark green, homogeneous, and had a characteristic odor. Phytochemical screening indicated the presence of alkaloids, flavonoids, tannins, polyphenols, steroids, and monoterpenoids/sesquiterpenoids, whereas quinones and saponins were not detected. The water- and ethanol-soluble extractive values were 0.1137 ± 0.0401% and 0.2119 ± 0.0095%, respectively. Loss on drying was 0.0106 ± 0.0017%, specific gravity was 0.8802 ± 0.0029 g/mL, total ash was 0.5543 ± 0.0434%, water-soluble ash was 0.4859 ± 0.0405%, and acid-insoluble ash was 0.4845 ± 0.0229%. Overall, the ethanol-soluble extractive value, loss on drying, specific gravity, and ash parameters were relatively consistent, whereas the water-soluble extractive value showed considerable variation. These findings provide a preliminary standardization profile for the n-hexane extract of Begonia × erythrophylla Herincq leaves. However, the water-soluble extractive value and relationships among ash parameters require verification before being established as quality specifications for herbal raw materials.
Bahaya Cemaran Logam dalam Produk Farmasi Ermi Abriyani; Lia Fikayuniar; Diany Astuti
Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 1 (2026): Edisi: November-Januari
Publisher : Pustaka Bangsa Indonesia

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Abstract

Cemaran logam dalam produk farmasi merupakan isu keamanan yang penting karena logam toksik dapat masuk ke dalam produk melalui bahan baku, peralatan, proses produksi, maupun lingkungan. Kegiatan pengabdian ini bertujuan memberikan edukasi kepada masyarakat mengenai cemaran logam dalam produk farmasi, sumber cemaran, potensi dampak kesehatan, serta langkah sederhana untuk mengurangi risiko paparan. Kegiatan dilaksanakan di Desa Cibuntu pada 25 Juli 2026 dan dihadiri oleh masyarakat serta anggota Ibu PKK. Metode kegiatan berupa penyuluhan, pembagian leaflet, tanya jawab dan diskusi interaktif, serta pemberian doorprize. Kegiatan diakhiri dengan foto bersama. Selama penyuluhan, peserta menunjukkan keterlibatan melalui pertanyaan dan diskusi mengenai jenis logam, produk yang berpotensi tercemar, serta keamanan produk farmasi. Kegiatan ini menjadi sarana edukasi untuk meningkatkan kewaspadaan masyarakat terhadap cemaran logam dan pentingnya memilih produk farmasi yang memenuhi persyaratan keamanan.
Co-Authors Abriyani, Ermi Delika Syalomita Farhamzah Fikayuniar, Lia Putri Agustina