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Jurnal Ilmiah Kedokteran Wijaya Kusuma
Published by Universitas Wijaya Kusuma Surabaya
ISSN : 19782071     EISSN : 25805967     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health
Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.
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Articles 10 Documents
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Search results for , issue "Vol 1, No 1 (2012): Edisi Juli 2012" : 10 Documents clear
ADDISONS DISEASE Sanjaya, Ayling
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Penyakit Addison (Addisons disease) adalah kelainan yang disebabkan oleh ketidakmampuan korteks adrenalis memproduksi hormon kortisol dan aldosteron. Keadaan tersebut dapat disebabkan oleh insufisiensi adrenal primer seperti autoimun, infeksi dan tumor adrenal atau insufisiensi adrenal sekunder karena tumor atau infeksi, kurangnya aliran darah ke kelenjar hipofisis, radiasi kelenjar hipofisis, atau pengangkatan bagian hipotalamus atau kelenjar hipofisis. Penyakit Addison ini sangat jarang terutama pada anak-anak. Penyakit Addison dapat terjadi baik pada pria maupun wanita di semua usia. Frekuensi penyakit Addison pada populasi manusia diperkirakan 1 dari 100.000. Diagnosis penyakit Addison dapat dibuat melalui gambaran klinis dan pemeriksaan laboratorium. Pemeriksaan radiologis seperti CT Scan dan MRI dapat membantu menganalisa kelenjar adrenal dan kelenjar hipofise sehingga dapat diketahui penyebab insufisiensi kortisol yang terjadi pada penderita. Terapi penyakit Addison yaitu penggantian atau subtitusi hormon kortisol memperbaiki defisiensi glukokortikoid dan terapi standar pada keadaan krisis Addison. Diagnosis dini dan terapi yang tepat diperlukan untuk memberikan prognosis yang baik bagi pasien Addisons disease.
EXERCISE STRESS TESTING : WHEN, HOW, AND WHAT IT MEANS? Waskito, Budi Arief
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Exercise stress testing (EST) is a sensitive and informative examination of the cardiovascular response to exercise. Exercise is a common physiological stress used to elicit cardiovascular abnormalities not present at rest and to determine the adequacy of cardiac function. The electrocardiogram is the most common parameter used to evaluate the ischemic response during exercise. Exercise electrocardiography is one of the most frequent noninvasive modalities used to determine the likelihood and extent of coronary artery disease. The test is also used to estimate prognosis, to determine functional capacity, and to evaluate the effects of therapy. The indications, contraindications, protocol, when to terminate, interpretation of the result, and spesific clinical applications will be reviewed in this paper.
INFLUENCES OF RESISTANT POWER EXERCISE WITH INTAKE KARNITIN SUPPLEMENT TO IMPROVEMENT FREE FAT ACID AND VO2 MAX Soesanto, Wibisono
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Sport achievement basically depends on four main factor readiness, that are physical, technical, tactical and mental readiness (Bompa, 1990). Physical readiness is a base or foundation for sport achievement, because superfine physical ability will also provide fine technical, tactical and mental ability. Athletes physical ability determined by one of the main body fit parameters, that is VO2 max. This study wants to measure the difference between influences of endurance exercise with carnitine supplement administration and endurance exercise without carnitine supplement administration toward the increased free fatty acid and VO2 max.This is a kind of experimental study and, according to the place, is a field experiment with Randomized Pretest – Posttest Control Group Design. Treatment at group 1 was provided continual endurance exercise with low intensity three times a week for two months supplemented with carnitine administration of 1.6 g carnitine/exercise. Group 2 was provide endurance exercise treatment continually with low intensity 3 times a week for two months supplemented with carnitine administration of 0.8 g carnitine/exercise and group 3 was provided with continual endurance exercise with low intensity 3 times a week for two months. After the treatment completed for two months, each tested person from group 1 through group 3 was given a posttest by their blood sample withdrawal to measure Free Fatty Acid using Calorimetric method and VO2 max measurement using Treatmill.With anova statistic it was obtained F = 11.924 and p = 0.000. Because p < 0.05, then, there was a significant difference of Free Fatty Acid for the three study groups. Group 1 increment (1.6 g of carnitine supplement each continual endurance exercise with low intensity) was higher than group 2 (0.8 g of carnitine supplement for each continual endurance exercise with low intensity) and group 2 increment (administration of 0.8 g carnitine supplement each continual endurance exercise with low intensity) was higher than group 3 (continual endurance exercise with low intensity without carnitine supplement administration). With anova statistic test it was obtained F = 23.756 and p = 0.000. Because p < 0.05, then, there was difference meaning of VO2 max for the three study groups. Group 1 increment (1.6 g carnitine supplement administration each continual endurance exercise with low intensity) was higher than group 2 (0.8 g carnitine supplement administration for each continual endurance exercise with low intensity) and group 2 (0.8 carnitine supplement administration for each continual endurance exercise with low intensity) was higher than group 3 (continual endurance exercise with low intensity without carnitine supplement)
EFFECT OF ZINC ADMINISTRATION TOWARD TO DIFFERENCE OF INCREASING NUTRITION STATUS ON HIV / AIDS PATIENTS Sahadewa, Sukma
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Nutrition had the important role in patient with HIV/AIDS, it increased the immune system and delayed the progression of HIV into AIDS. Zinc played a role in optimizing immune function, especially in T cell, need for accelerating growth process, stabilized structure of cell membranes and activated growth hormone. The purpose of this study was to analyze the differences in weight and albumin levels after administration of zinc sulfate in patients with HIV/AIDS. This research is experimental research with randomized pretest posttest control group design with the provision of a double-blind treatment. Data collection techniques using questionnaire, food recall, food frequency questionnaire, anthropometry, blood sampling and laboratory examination. The results showed that there were significant differences in body weight between before and after zinc administration in the treatment group (p = 0.030), whereas in the control group showed no significant differences in body weight between before and after zinc administration (p = 0.839 ). T-test results of elevated levels of albumin difference between before and after zinc administration between the treatment and control groups showed that there were significant difference with p value = 0.673.
Uji Widal (Widal Test) Sudibya, Akhmad
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Widal Test is one of the application of diagnostic immunology in the diagnosis of typhoid fever. Widal Test must be taught at the school of medicine although some physicians opines that this test is quite obsolete. In real life there are stillmany physicians in developing countries who consider this test as very instrumental in the diagnosis of typhoid fever.
REACTION BIOMARKER MONOCLONAL FRAGMENTATION OF COLLAGEN TYPE IV WITH BLOOD SERUM ACUTE MYOCARDIAL INFARCTION PATIENT RELATED INFECTION Muliartha, Ketut
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Penelitian ini bertujuan untuk mendeteksi penyakit jantung akut myocardial infark dengan menggunakan biomarker antibodi monoclonal fragmentasi kolagen tipe IV. Rupture plak aterosklerosis adalah terjadi karena degradasi kolagen tipe IV. Perviromonas gingivalis adalah salah satu faktor resiko yang terpenting untuk terjadinya akut myocard infark (AMI). Rancangan penelitian ini adalah ekperimental invitro dengan deksriptif cross sectional. Sampel penelitian adalah empat orang sehat (n=4) serta 12 penderita AMI (n=12). Untuk melihat ekpresi enzim MMP-9 dan fragmentasi kolagen tipe IV, kami menggunakan teknik western bloting. Untuk mengisolasi sel limfosit, kami mengimunisasi mencit dengan antigen fragmentasi kolagen tipe IV disertai dengan adjuvant. Selanjutnya dilakukan fusi antara sel limfosit dengan sel myeloma sehingga terbentuk hibridoma dan diuji dengan western bloting serta ELISA teknik. Kemudian dilakukan seleksi klon. Selanjutnya dilakukan insersi pada intra peritoneal sehingga terbentuk ascites. Hasil penelitian ini menunjukkan bahwa MMP-9 muncul pada 92 kDa dan fragmentasi kolagen tipe IV dengan band 60 – 80 kDa. Untuk menguji reaksi monoklonal antibodi fragmentasi kolagen tipe IV dilakukan uji 12 sampel penderita AMI. Hasilnya semua sampel AMI positif. Kesimpulan menunjukkan bahwa biomarker monoklonal antibodi fragmentasi kolagen tipe IV ternyata bereaksi positif pada penderita AMI.
SJOGRENS SYNDROME Rahmawati, Febtarini
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Sjogrens syndrome merupakan salah satu jenis penyakit auto imun non spesifik organ yang sering terjadi secara bersamaan dengan penyakit auto imun lainnya. Sebagian besar diderita oleh wanita usia diatas 40 tahun, dengan gejala kelenjar air liur dan air mata kering. Pemeriksaan laboratorium penyaring penyakit auto imun adalah ANA (anti nuklir antibodi) test. Bila pemeriksaan ANA (anti nuklir antibodi) positif, dilanjutkan pemeriksaan konfirmasi auto antibodi imunoblotting, untuk mengetahui konsentrasi band antibodi anti-SSA/antibodi terhadap sjogrens syndrome antigen A (Ro) atau antibodi anti-SSB/antibodi terhadap sjogrens syndrome antigen B (La) yang positif.
Uji Widal (Widal Test) Akhmad Sudibya
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (53.062 KB) | DOI: 10.30742/jikw.v1i1.31

Abstract

Widal Test is one of the application of diagnostic immunology in the diagnosis of typhoid fever. Widal Test must be taught at the school of medicine although some physicians opines that this test is quite obsolete. In real life there are stillmany physicians in developing countries who consider this test as very instrumental in the diagnosis of typhoid fever.
SJOGREN'S SYNDROME Febtarini Rahmawati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (146.515 KB) | DOI: 10.30742/jikw.v1i1.50

Abstract

Sjogren's syndrome merupakan salah satu jenis penyakit auto imun non spesifik organ yang sering terjadi secara bersamaan dengan penyakit auto imun lainnya. Sebagian besar diderita oleh wanita usia diatas 40 tahun, dengan gejala kelenjar air liur dan air mata kering. Pemeriksaan laboratorium penyaring penyakit auto imun adalah ANA (anti nuklir antibodi) test. Bila pemeriksaan ANA (anti nuklir antibodi) positif, dilanjutkan pemeriksaan konfirmasi auto antibodi imunoblotting, untuk mengetahui konsentrasi band antibodi anti-SSA/antibodi terhadap sjogren's syndrome antigen A (Ro) atau antibodi anti-SSB/antibodi terhadap sjogren's syndrome antigen B (La) yang positif.
ADDISON'S DISEASE Ayling Sanjaya
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.294 KB) | DOI: 10.30742/jikw.v1i1.51

Abstract

Penyakit Addison (Addison's disease) adalah kelainan yang disebabkan oleh ketidakmampuan korteks adrenalis memproduksi hormon kortisol dan aldosteron. Keadaan tersebut dapat disebabkan oleh insufisiensi adrenal primer seperti autoimun, infeksi dan tumor adrenal atau insufisiensi adrenal sekunder karena tumor atau infeksi, kurangnya aliran darah ke kelenjar hipofisis, radiasi kelenjar hipofisis, atau pengangkatan bagian hipotalamus atau kelenjar hipofisis. Penyakit Addison ini sangat jarang terutama pada anak-anak. Penyakit Addison dapat terjadi baik pada pria maupun wanita di semua usia. Frekuensi penyakit Addison pada populasi manusia diperkirakan 1 dari 100.000. Diagnosis penyakit Addison dapat dibuat melalui gambaran klinis dan pemeriksaan laboratorium. Pemeriksaan radiologis seperti CT Scan dan MRI dapat membantu menganalisa kelenjar adrenal dan kelenjar hipofise sehingga dapat diketahui penyebab insufisiensi kortisol yang terjadi pada penderita. Terapi penyakit Addison yaitu penggantian atau subtitusi hormon kortisol memperbaiki defisiensi glukokortikoid dan terapi standar pada keadaan krisis Addison. Diagnosis dini dan terapi yang tepat diperlukan untuk memberikan prognosis yang baik bagi pasien Addison's disease.

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