Article Per Year (5 Year)
p-Index From 2020 - 2025
0.983
P-Index
This Author published in this journals
All Journal Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Health Sains Jurnal Pengabdian Masyarakat: Humanity and Medicine DUNIA KEPERAWATAN: JURNAL KEPERAWATAN DAN KESEHATAN Calvaria Medical Journal
Febtarini Rahmawati
Medical Faculty Airlangga University/Dr. Soetomo Hospital, Surabaya
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

Published : 9 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 9 Documents
Search

 1 
INTERLEUKIN-6 (IL-6) LEVEL AS AN INDIKATOR OF PROGRESIVITY RHEUMATOID ARTHRITIS (RA) DISEASE Tania, Putu Oky Ari; Simamora, Dorta; Parmasari, Wahyuni Dyah; Rahmawati, Febtarini
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 3, No 1 (2014): Edisi Maret 2014
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Rheumatoid Arthritis (RA) is autoimmune disease that attacks joints and synovial tissues. Rheumatoid Arthritis is characterized by inflammation that involves production of cytokines such as Interleukin 6 (IL-6). Increasing of interleukin 6 has correlation with activity and progressivity of the disease. This research was designed to know whether IL- 6 could be used as indicator progressivity of RA. The method that used for measuring IL-6 level is ELISA (Enzyme Linked Immunosorbent Assay), using the principle antigen-antibody binding. In early stage there were 9 persons (S01, S02, S03, S04, S07, S08, S09, S10 and S14) with of IL-6 level (mean : 3.640 pg/mL), intermediate stage there were 3 persons (S06, S13 and S15) with IL-6 level (mean : 12.453 pg/mL), late stage : 3 persons (S05, S11 and S12) with IL-6 level (mean : 59.349 pg/mL).
ASPEK LABORATORIUM Acute Promyelocytic Leukemia (APL) AML-M3 Rahmawati, Febtarini
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2013): Edisi Mei 2013
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Acute Promyelocytic Leukemia (APL) adalah subtipe M3 dari Acute Myelogenous Leukemia (AML), sesuai klasifikasi French-American-British (FAB). APL mempunyai beberapa varian yang bisa dibedakan dari pemeriksaan molekular dan sitogenetika. Lebih dari 95% APL hipergranular (M3 klasik), 15%-20% dari APL adalah varian mikrogranular (hipogranular, M3v) dan varian APL yang jarang (<1%) adalah basofilik dan Promyelocytic leukemia zinc finger        (PLZF/M3r).Gejala klinis penderita APL yakni anemia meliputi pusing, kelelahan, sesak ketika kerja fisik, pucat. Perdarahan terjadi karena pasien dengan APL mengalami penurunan jumlah trombosit dan gangguan sistem koagulasi. Sel darah putih pada umumnya meningkat ditandai dengan gejala panas badan dan infeksi serta pembesaran limpa juga nyeri tulang akibat infiltrasi sel-sel leukemia ke periosteal.Tes skrining penderita leukemia akut adalah pemeriksaan darah rutin dan evaluasi sediaan hapusan darah tepi. Pemeriksaan penunjang diagnostik lainnya adalah hapusan dari aspirasi sumsum tulang, pengecatan sitokimia, Immunophenotyping, sitogenetika dan biologi molekular. White blood cell (WBC) > 10 X 109/L, trombositopenia < 50 X 109/L. Hapusan darah tepi pasien dengan APL didapatkan gambaran eritrosit normokromik normositik dengan poikilositosis dan kadang-kadang normoblas. Gambaran sel-sel muda didominasi oleh promielosit. Sebagian besar hipergranular, morfologi mieloblasnya dengan nukleus berlekuk dan Auer rod. Pada hapusan sumsum tulang umumnya hiperseluler dengan jumlah sel-sel muda promielosit ≥30%. Morfologi promielosit pasien dengan APL lebih besar daripada promielosit normal. Auer rods positif kadang-kadang didapatkan faggots cell. Aktivitas eritropoiesis dan trombopoiesis tertekan. Varian hipergranular APL diketahui dengan pemeriksaan sitokimia, immunophenotyping, sitogenetika dan teknologi biologi molekuler.
SJOGRENS SYNDROME Rahmawati, Febtarini
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sjogrens syndrome merupakan salah satu jenis penyakit auto imun non spesifik organ yang sering terjadi secara bersamaan dengan penyakit auto imun lainnya. Sebagian besar diderita oleh wanita usia diatas 40 tahun, dengan gejala kelenjar air liur dan air mata kering. Pemeriksaan laboratorium penyaring penyakit auto imun adalah ANA (anti nuklir antibodi) test. Bila pemeriksaan ANA (anti nuklir antibodi) positif, dilanjutkan pemeriksaan konfirmasi auto antibodi imunoblotting, untuk mengetahui konsentrasi band antibodi anti-SSA/antibodi terhadap sjogrens syndrome antigen A (Ro) atau antibodi anti-SSB/antibodi terhadap sjogrens syndrome antigen B (La) yang positif.
Aspek Laboratorium Gagal Ginjal Kronik Rahmawati, Febtarini
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 6, No 1 (2017): Edisi Maret 2017
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (100.874 KB) | DOI: 10.30742/jikw.v6i1.323

Abstract

Chronic renal disease is a disorder of renal function or structure that lasts for more than three months, accompanied by a decrease in glomerular filtration rate. Decreasing of renal function monitoring is performed by measuring glomerular filtration rate, determining blood urea, creatinine, creatinine clearance, electrolytes, uric acid, blood gas analysis and tubular function. The Recent method for measuring glomerular filtration rate using inulin clearance, however, is not efficient. Further measurements of creatinine glomerular filtration rate were developed. Measurements of urea, creatinine and uric acid are currently using enzymatic methods of spectrophotometry, while electrolyte examination by selective ion electrode method. Blood gas analysis determined pH, PCO2, PO2, HCO3-, CO2 total, base excess and SO2. Examination of urine protein and urine sediments helps establish a diagnosis of chronic kidney disease
Peningkatan pengetahuan “Pentingnya Perilaku Hidup Bersih dan Sehat” pada Posyandu Remaja Mojo Gubeng Surabaya Purbowati, Rini; Soekanto, Ayly; Rahmawati, Febtarini; Tjandra, Lusiani; Masfufatun; Devi Dwi Rianti, Emilia; Kumala Indahsari, Noer
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 3 No 1 (2022): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V3I1.72

Abstract

Indonesia is currently facing a double burden of diseases, namely Communicable Diseases (PM) and Non-Communicable Diseases (NCD) which are strongly influenced by changes in the environment, community behavior, demographic transition, technology, economy, and socio-culture. To overcome this problem, the government has intensified the Program Perilaku Hidup Bersih dan Sehat (PHBS), which should involve all elements of society, stakeholders, the private sector, academia, and non-governmental organization (NGOs) and other sectors. The role of young people is needed by the government in the process of sustainable development or the Sustainable Development Goals (SDGs). The purpose of this activity is to increase public knowledge and awareness, especially among members of the Youth Posyandu Mojo Gubeng Surabaya about the importance of clean and healthy living behavior. This service activity was carried out on Saturday 11 September 2021, attended by 26 participants. This community service activity was chosen in the form of an online seminar (webinar) to support the government in handling COVID-19 by implementing Emergency PPKM. Measurement of the increase in participants' knowledge was carried out through pre-test and post-test by answering questions related to the webinar material by filling out Google Forms. The measurement results obtained a pre-test average and post-test average value (82.1±18) with a delta value (change in score) of 18.6. Community Service Activities through a Webinar with the title "The Importance of Healthy Lifestyle Behavior at the Youth Posyandu Mojo Gubeng Surabaya" can increase public knowledge at the Mojo Youth Posyandu Surabaya.
Effect of Ashitaba Extract on Cholesterol in Wistar Rats given a high-fat diet and computational lethal dose test Widyaningsih, Indah; Sugiharto, Natsya Nurulita; Rahmawati, Febtarini; Amma, Fuad; Simamora, Dorta
Dunia Keperawatan: Jurnal Keperawatan dan Kesehatan Vol 12 No 2 (2024): Dunia Keperawatan: Jurnal Keperawatan dan Kesehatan
Publisher : School of Nursing, Faculty of Medicine and Health Science, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jdk.v12i2.570

Abstract

High levels of cholesterol in the blood can cause various health problems, namely atherosclerosis, stroke, coronary heart disease, to hypertension. One drug option for someone with hypercholesterolemia is simvastatin. In addition to the use of the drug simvastatin, can take medicinal plants. A medicinal plant that can help lower high cholesterol levels is Ashitaba leaf extract (Angelica keiskei). One of the ingredients in ashitaba extract is xanthoangelol E, Ashitaba chalcones, which can reduce cholesterol synthesis. The purpose of this study was to determine the effect of ashitaba extract (Angelica keiskei) on the cholesterol levels of Wistar rats (Rattus novergiccus) given a high-fat diet. In this study, a computational lethal dose test was also carried out. The population in this study was male white rats of the Wistar strain with samples taken from as many as 30 heads. Data analysis of this study used the One Way Anova statistical test. The results showed that giving ashitaba extract 150mg/kg body weight, 300mg/kg body weight, and 600mg/kg body weight did not affect the cholesterol levels of Wistar rats given a high-fat diet. This is proven by the results of the ANOVA test obtained a significance value of 0.761 > 0.05. Research on the toxic effects of ashitaba extract needs to be done for further research.
Hubungan Angka Kejadian Metabolik Sindrom dengan Dislipedimia: Studi Literatur Abrori, Amiril; Rahmawati, Febtarini; Listyawati, Agusniar Furkani
Calvaria Medical Journal Vol 1 No 2 (2023): Edisi Desember 2023
Publisher : Institute for Research and Community Services (LPPM) of University of Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/cmj.v1i2.20

Abstract

Introduction: Metabolic syndrome is a composite of multiple cardiovascular disorders characterized by abdominal/central obesity, increased blood sugar, blood pressure, triglycerides, and decreased high-density lipoprotein (HDL). As a result of disorders caused by Metabolic Syndrome which causes one of the diseases       Dyslipidemia. The purpose of this        study was to determine the relationship between the incidence of Metabolic Syndrome and Dyslipidemia. Method: This study used a literature study research method which was carried out by collecting data through literature searches or electronic-based literature reviews using internet media. Result: In this literature review, the authors cite thirty journals consisting of eighteen national journals and twelve international journals. Twenty-five journals in this study showed a correlation between the relationship between the incidence of metabolic syndrome and dyslipidemia. junk food and lack of regular exercise. Conclusion: There is a relationship between the incidence of metabolic syndrome and dyslipidemia. Keywords: Incidence Rate, Metabolic Syndrome, Dyslipidemia
Tingkat Pengetahuan dan Kesadaran Masyarakat Akan Deteksi Kanker Serviks di Lingkungan RW 12 Pondok Wage Indah 2 Sidoarjo Hernanda, Pratika; Wardhani, Mira Kusuma; Rahmawati, Febtarini; Agusaputra, Harman
Calvaria Medical Journal Vol 1 No 2 (2023): Edisi Desember 2023
Publisher : Institute for Research and Community Services (LPPM) of University of Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/cmj.v1i2.22

Abstract

Introduction: Cervical cancer is a malignant tumor that attacks the surface layer of the cervix, called squamous epithelial cells, which are located between the uterus and the vagina. It is important for women to know what factors can cause cervical cancer and have knowledge about preventing cervical cancer because the incidence of cervical cancer is still high in Indonesia, and there are still many women who lack knowledge. Method: A descriptive research design with a sample size of 33 people used total sampling of respondents who underwent pap smear examinations during Early Detection of Cervical Cancer event in RW 12 - Pondok Wage Indah 2 Sidoarjo. The data will be analyzed with a quantity test using SPSS software. Results: This research shows that the average age of respondents iss 48 years, as many as 47.2% of respondents have high education (minimum D3), the majority are housewives (IRT) as many as 25 people (69.4%), and the majority 23 people (63.9%) had good knowledge of cervical cancer risk factors, 9 people (25%) had sufficient/moderate knowledge and 1 person (2.8%) had poor knowledge. Conclusion: Respondents who underwent pap smear examinations mostly had a good level of knowledge about cervical cancer.
Effect of Ashitaba Extract on Cholesterol in Wistar Rats Given a High-Fat Diet and Computational Lethal Dose Test Widyaningsih, Indah; Nurulita Sugiharto, Natasya; Rahmawati, Febtarini; Amma, Fuad; Simamora, Dorta
Jurnal Health Sains Vol. 5 No. 10 (2024): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i10.1365

Abstract

High cholesterol levels in the blood can cause various health problems, namely atherosclerosis, stroke, coronary heart disease, and hypertension. One drug option for someone with hypercholesterolemia is simvastatin. Apart from using simvastatin, you can consume medicinal plants. A medicinal plant that can help reduce high cholesterol levels is Ashitaba (Angelica keiskei) leaf extract. One of the ingredients in Ashitaba extract is xanthoangelol E, Ashitaba chalcones, which can reduce cholesterol synthesis. The aim of this research was to determine the effect of ashitaba (Angelica keiskei) extract on the cholesterol levels of Wistar rats (Rattus novergiccus) given a high-fat diet. In this study, a computational lethal dose test was also carried out. The population in this study was male white rats of the Wistar strain with 30 samples taken. Analysis of this research data uses the One Way Anova statistical test. The results of the study showed that giving ashitaba extract 150mg/kg BW, 300mg/kg BW, and 600mg/kg BW had no effect on the cholesterol levels of Wistar rats given a high-fat diet. This is proven by the results of the Anova test which obtained a significance value of 0.761 > 0.05. Research regarding the toxic effects of ashitaba extract needs to be carried out for further research.
Co-Authors Abrori, Amiril Amma, Fuad Ayly Soekanto Devi Dwi Rianti, Emilia Dorta Simamora HARMAN AGUSAPUTRA Hernanda, Pratika Indah Widyaningsih Listyawati, Agusniar Furkani Lusiani Tjandra Masfufatun Noer Kumala Indahsari, Noer Kumala Nurulita Sugiharto, Natasya Putu Oky Ari Tania Rini Purbowati Sugiharto, Natsya Nurulita Wahyuni Dyah Parmasari, Wahyuni Dyah Wardhani, Mira Kusuma