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Florentinus Dika Octa Riswanto
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Jurnal Farmasi Sains dan Komunitas
Published by Universitas Sanata Dharma
ISSN : 16935683     EISSN : 25277146     DOI : https://doi.org/10.24071/
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community / J Pharm Sci Community) firstly published in 2003, is a peer-reviewed, open access scientific journal that publishes research articles, review articles, as well as short communication in various pharmaceutical fields, including Pharmaceutical Technology and Pharmaceutics, Pharmaceutical Analysis, Medicinal Chemistry, Pharmacology and Toxicology, Pharmaceutical Biology, Community Pharmacy, and Clinical Pharmacy.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 13 Documents
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Search results for , issue "Vol 21, No 1 (2024)" : 13 Documents clear
Preparation and Characterization of Binahong (Anredera cordifolia) Leaf Extract Transfersome Wound-Healing Gel Immanuel, Handika; Yuliani, Sri Hartati; Dwiastuti, Rini; Nugraha, Alvin Arya; Limianty, Angela; Annabel, Evangeline Keisha; Lu, Felisha; Lestari, Fajar Sri; Branitasandini, Regina Epiphania
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 1 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007311

Abstract

Burn injuries are a significant global health concern due to their profound impact on morbidity and mortality rates. Immediate medical care is essential given the potential for bacterial infections to complicated burn injuries. Binahong leaves (Anredera cordifolia (Ten.) Steenis) contain vitexin compounds that demonstrate wound healing and antibacterial potential. However, vitexin has low solubility, prompting the use of ethanol for extraction and the introduction of nanoparticle technology to enhance solubility, namely transfersomes. The present study explored the development of a gel using binahong extract transfersomes with the composition of carbopol 940 and Na-CMC to determine the effect of carbopol 940, Na-CMC, and the interaction of the two on the gel’s physical properties and stability as well as obtain the optimum composition of the two. This study demonstrates positive results in terms of gel physical properties, including pH, spreadability, and viscosity. A Factorial design method is used for optimization. The results showed that Na-CMC had the most effect on increasing viscosity, while carbopol 940 had the most effect on reducing spreadability. The optimal formula obtained in this research was to use 0.653 grams of Na-CMC and 4.391 grams of Carbopol as gelling agents. 
Formulation of Wound Healing Hydrogel from 70% Ethanol Extract of Kelakai Roots (Stenochlaena palustris (Burm. F.) Bedd) with Polymer Combination of PVA/HPMC Forestryana, Dyera; Pebrianie, Shilpa; Ramadhan, Hafiz; Restapaty, Ratna
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 1 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.005291

Abstract

Kelakai root contains alkaloids, saponins, tannins, and flavonoids. This compound is known to have medicinal properties such as wound healing. The effectiveness of wound healing increased by using hydrogel to deliver the active substance. The use of polymers played a role in delivering the active substance. This study aimed to formulate hydrogels for wound healing with various concentrations of polyvinyl alcohol (PVA) and hydroxy propyl methyl cellulose (HPMC) K4M. Preparation of hydrogel by the solvent casting method used 0.2% Kelakai root extract. The physical characteristics of hydrogel investigated before and after the stability test included organoleptic, weight uniformity, thickness, pH, moisture content, and hedonic test of Kelakai roots extract hydrogel.  The optimum formula was tested for wound healing activity. The data obtained were then analyzed using Wilcoxon testswith p0.05 considered significant. Physically, Kelakai root extract hydrogel met the test requirements. The results of the wound-healing activity showed that the hydrogel extract of the Kelakai root was able to heal the wounds within seven days. There was a significant difference in wound healing time with p=0.014. The optimum formula obtained based on the stability test was F4 with a 1:4 ratio of PVA and HPMC. 
Implementation of Hospital Management Information Systems: Obstacles and Challenges (Case Study at Santo Antonio Baturaja Hospital) Sumiyem, Sr. M. Karla; Hartayu, TB. Titien Siwi
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 1 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.006777

Abstract

The Hospital Information System (HIS) handles and integrates the entire flow of hospital services. This study aimed to identify factors that affect the effectiveness and efficiency of HIS implementation and select strategies that can be used to overcome the inhibiting factors. In-depth interviews were used in this study with a qualitative and case-study strategy. The respondents were 26 officers selected by non-random purposive sampling. Data analysis used triangulation of in-depth interviews, document observations, and observations of HIS implementation. Data were transcribed verbatim and analyzed thematically. The results showed that the positive behavior of officers, leadership support, and officer abilities supported the implementation of HIS. However, there are still obstacles due to the attitude of officers and management policies. From document observations, it was found that officers had incorrect input, doubled input, and forgotten input. Due to a lack of Standard Operating Procedures (SOPs) and guidelines for implementing HIS, observations on its deployment revealed inconsistent data input. The strategy suggested to deal with the barriers included designing monitoring programs, creating SOPs, conducting extensive socializing programs, and conducting training programs to enhance officers' soft skills. It is clear that Human Resources play a crucial role for the effectiveness of HIS implementation. 

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