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All Journal Jurnal Farmasi Sains dan Komunitas Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) JSFK (Jurnal Sains Farmasi & Klinis) Yumary: Jurnal Pengabdian kepada Masyarakat Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Majalah Cendekia Mengabdi Jurnal Pengabdian Masyarakat Wadah Publikasi Cendekia
Forestryana, Dyera
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Physics Public Health Social Sciences Other

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INKORPORASI MIKROEMULSI EKSTRAK ETANOL AKAR KELAKAI (Stenochlaena Palustris (Burn. F) Bedd.) PADA FORMULASI TONER WAJAH DENGAN VARIASI KONSENTRASI GLISERIN Forestryana, Dyera; Muawiyyah, Walidatun; Indah Sayakti, Putri
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1706

Abstract

The face is one part of the human body that needs to be kept healthy and clean. Efforts can be made to maintain facial cleanliness by using facial toner. The extract of kelakai root has activity as an antioxidant. Incorporation of kelakai root extract microemulsion in the toner formulation will increase the cleaning ability and optimal absorption of active substances. This research aims to obtain an optimum face toner formula. The kelakai roots were macerated with 70% ethanol solvent. The kelakai microemulsion consisted of Tween 80 35% w/v and PEG 400 15% w/v. Incorporation of 2% w/v microemulsion into the toner formula with varying glycerin concentrations of 2%, 3%, 4%, and 5% w/v. Evaluation through stability tests with organoleptic, homogeneity, pH, viscosity, clarity, and density. Organoleptic, homogeneity, and clarity before and after the stability test provide a liquid form, odorless, clear, and homogeneous color. In the pH test, the pH value of the preparation was stable in the pH range of 4.5-6.5. The viscosity of toner preparations is in a range of 1-24.5 cPs. The density stability with a range of 1.003-1.015 gr/mL. The optimum formula, namely F2 with 3% glycerin, provides good toner stability based on physical quality tests.
DAUN Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz SEBAGAI ANTI-Escherichia coli: STUDI IN SILICO DAN IN VITRO Ramadhan, Hafiz; Forestryana, Dyera; Jamaludin, Wahyudin Bin; Hadi, Ahmad Nur; Raudatunnisa
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 2023: Webinar Nasional & Call For Paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i3.1701

Abstract

This research was conducted to determine the potential of phytochemical contents in producing antibacterial activity from 70% ethanol extract of Balik Angin leaves  (Alphitonia incana (Roxb.) Teijsm . & Binn. ex Kurz) against Escherichia coli bacteria in silico and in vitro. In silico assay of 20 compounds contained in Alphitonia species against the DNA gyrase receptor using PLANTs. Anti-E.coli activity assay of Balik Angin leaves macerated with 70% ethanol solvent using the Well diffusion method. In silico studies show that β-Sitosterol, Stigmasterol, Rutin, Kaempferol 3-O-rutinoside, and Zizyphoiside C have binding energies with DNA gyrase that can exceed Ciprofloxacin. The antibacterial assay results at a highest concentration of 26.56 mg/ml can provide an average inhibitory zone diameter of 12.75 ± 0.2 mm with a minimum inhibitory concentration (MIC) of 1.66 mg/ml (5.87 ± 1.5 mm). The 70% ethanol extract of Balik Angin leaves has the potential as an anti-Escherichia coli, supported by the content of phytochemical compounds that can act as DNA gyrase inhibitors.
Peningkatan Pengetahuan Kader Kesehatan Terhadap Penyakit Diabetes Melitus Di Desa Kalampayan Tengah, Kabupaten Banjar Forestryana, Dyera; Rusida, Esty Restiana; Arsyad, Muhammad
Majalah Cendekia Mengabdi Vol 1 No 4 (2023): Majalah Cendekia Mengabdi
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/mcm.v1i4.296

Abstract

Pendahuluan: Kesehatan merupakan hal yang sangat diinginkan setiap manusia, karena dengan sehat setiap orang dapat melakukan aktivitas dengan lancar tanpa gangguan, dapat melakukan suatu pekerjaan, dan atau beberapa pekerjaan secara maksimal. Kemajuan ilmu pengetahuan dan teknologi serta perbaikan sosial ekonomi berdampak pada peningkatan derajat kesehatan masyarakat dan usia harapan hidup. Dewasa ini manusia melalaikan pentingnya menjaga kesehatan khususnya secara jasmani. Dilain pihak kurangnya pengetahuan dan pemahaman akan pentingnya kesehatan.Tujuan: Meningkatkan derajat kesehatan masyarakat melalui kader posyandu.Metode: Metode yang digunakan dalam kegiatan Pengabdian Masyarakat ini melibatkan secara langsung partisipasi mitra dalam hal ini masyarakat yang dijadikan Kader Kesehatan. Kegiatan Pengabdian kepada Masyarakat ini melakukan transfer skill serta knowledge yang dimiliki ke mitra. Metode kegiatan pengabdian masyarakat ini berupa penyuluhan dan pelatihan.Hasil:  Hasil kegiatan menunjukkan adanya Peningkatan pengetahuan dan keterampilan kader dalam upaya untuk meningkatkan derajat kesehatan dalam hal pencegahan penyakit Diabetes Melitus.Simpulan: Kegiatan pengabdian kepada masyarakat terhadap kader kesehatan di desa Kalampayan Tengah Kabupaten Banjar telah berhasil meningkatkan pengetahuan dan keterampilan kader terhadap upaya pencegahan Diabetes Melitus di masyarakat melalui edukasi/penyuluhan dan pelatihan.
Formulasi Dispersi Padat Pentagamavunon-0 (PGV-0) dalam Bentuk Sediaan Hidrogel dengan Kombinasi Basis Polimer Kitosan-Agar-PVP Forestryana, Dyera; Ramadhan, Hafiz
JSFK (Jurnal Sains Farmasi & Klinis) Vol 7 No 1 (2020): J Sains Farm Klin 7(1), April 2020
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.7.1.66-75.2020

Abstract

Pentagamavunon-0 (PGV-0) merupakan analog kurkumin dengan stabilitas yang lebih baik. PGV-0 memiliki kapasitas sebagai antioksidan, namun mengalami metabolisme lintas pertama pada pemberian secara oral. Untuk meningkatkan efektivitasnya, PGV-0 dibuat dalam bentuk sediaan transdermal. PGV-0 memiliki kelarutan terbatas di dalam air sehingga dibuat ke dalam sistem dispersi padat dengan polyvinylpyrrolidone (PVP) untuk meningkatkan kelarutannya. Penelitian ini bertujuan untuk membuat formula dispersi padat PGV-0/PVP ke dalam matriks hidrogel. Sediaan matriks dibuat 3 formula dengan menggunakan basis polimer kitosan-agar-PVP dengan memvariasikan jumlah penggunaan PVP. Evaluasi sediaan meliputi organoleptis, bobot, ketebalan, pH, moisture content, moisture uptake, daya lipat dan drug content. Uji penetrasi in vitro dilakukan dengan menggunakan sel difusi Franz. Formula optimum yang diperoleh yaitu hidrogel dispersi padat PGV-0/PVP dengan perbandingan 1:1 (F2B) yang memiliki moisture content sebesar 1,2% ± 0,28% dan nilai fluks sebesar 121,6227μg cm-² jam-¹
The Effect of Different Soxhlet Extraction Solvents Towards AntiPropionibacterium acnes Activity of Balik Angin Leaves (Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz) : Pengaruh Perbedaan Pelarut Ekstraksi Soxhlet Terhadap Aktivitas AntiPropionibacterium acnes dari Daun Balik Angin (Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz) Ramadhan, Hafiz; Forestryana, Dyera; Subareng, Ahmad Rizal Maulana; Vebruati, Vebruati
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 11 No. 1 (2025): (March 2025)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2025.v11.i1.16634

Abstract

Background: Acne is a skin infection that may be induced by Propionibacterium acnes. Treatment of acne infection from natural ingredients native to Kalimantan such as Balik Angin or Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz can be an alternative therapy. Prior research indicates that leaves macerated with methanol and 70% ethanol solvents can inhibit the growth of P. acnes in the medium category with a Minimum Inhibitory Concentration (MIC) of 3.2%. Objectives: The research purpose is to compare the effect of the different solvents of soxhlet extraction on the antibacterial activity of Balik Angin leaves in inhibiting the growth of P. acnes. Material and Methods: Balik Angin leaves were extracted using the Soxhlet with two different solvents, which were methanol and 70% ethanol, then followed by phytochemical screening. The antibacterial activity assay was carried out by using well diffusion with each sample concentrations of 25.6%; 12.8%; 6.4%; 3.2%; 1.6%; 0.8%; 0.4%; and 0.2%. Results: Both extracts contained the same phytochemical groups, which were phenols, flavonoids, alkaloids, tannins, saponins, and triterpenoids. The antibacterial activity test results showed that both extracts had the same MIC of 0.8%. however, the 70% ethanol extract of Balik Angin leaves was able to provide a larger inhibition diameter average of 9.61±0.35 mm compared to the methanol extract of 9.20±0.22 mm. Nonetheless, there was no significant difference (p>0.05) between both concentrations, when compared to the range of 1.6-25.6%. Conclusions: The conclusion of this research is that differences in Soxhlet extraction solvents in Balik Angin leaves can affect its activity as an anti-Propionibacterium acnes agent.
Penerapan Simple Water Filter pada Masyarakat Desa Benua Raya, Kecamatan Bati-Bati, Kabupaten Tanah Laut Ramadhan, Hafiz; Forestryana, Dyera; Hasymi, Liana Fitriani; Sutomo, Sutomo; Khairunnisa, Amalia; Istikowati, Wiwin Tyas
Yumary: Jurnal Pengabdian kepada Masyarakat Vol. 5 No. 3 (2025): Maret
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/yumary.v5i3.3660

Abstract

Purpose: The aim of this community service is a form of disaster preparedness to prevent health problems through the implementation of simple water filters in Benua Raya Village, Bati-Bati District, Tanah Laut Regency. Methodology: Activities were carried out by implementing Clean and Healthy Living Behavior (PHBS) counseling and training on making simple water filters for community mothers and Posyandu cadres with a total of 52 people on September 18th, 2024. Results: The activity results showed that participants knew and understood the importance of PHBS, especially using clean and suitable water for daily life and when affected by natural disasters as a form of disease prevention. The percentage of knowledge before the activity was 80.77%-94.23%, which increased after the activity to 96.15%-100%. The level of knowledge and skills of participants in making simple water filters also increased from 44.23%-48.08% to 88.46%-94.23%. Conclusions: This activity concludes that counseling and training on making simple water filters can increase the awareness of the people of Benua Raya Village to implement PHBS and can be one of the family preparedness efforts in obtaining clean water when a flood disaster occurs. Limitations: The activity was only attended by Posyandu cadres and housewives. Contribution: The counseling, education, and training activities for the Benua Raya Village community need to be carried out consistently because they contribute to increased awareness of Clean and Healthy Living Behavior.
Pemberdayaan Ibu-Ibu Rumah Tangga Dalam Memanfaatkan Kelakai Sebagai Obat Tradisional Lokal Di Kelurahan Landasan Ulin Utara, Kalimantan Selatan Kurdiansyah; Forestryana, Dyera; Ramadhan, Hafiz; Andy Chandra, Muhammad; Vebruati
Jurnal Pengabdian Masyarakat Wadah Publikasi Cendekia Vol 1 No 2 (2024): Jurnal Pengabdian Masyarakat WPC
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/jpmwpc.v1i2.423

Abstract

Kalimantan Selatan merupakan salah satu provinsi di Indonesia yang luas daratannya hampir terdiri dari lahan basah berupa tanah gambut yang ditumbuhi berbagai tanaman yang dipercaya berkhasiat obat. Kelakai merupakan tanaman pakis yang berkhasiat sebagai obat penambah darah, memperbanyak ASI, serta menyembuhkan luka dan penyakit kulit. Pengabdian kepada masyarakat ini bertujuan untuk meningkatkan kesadaran masyarakat akan Kelakai sebagai obat tradisional di Kalimantan Selatan. Kegiatan ini berlokasi di Kecamatan Landasan Ulin Utara Kota Banjarbaru dengan peserta ibu-ibu rumah tangga. Kegiatan diawali dengan sosialisasi terkait Kelakai, kemudian dilanjutkan dengan pembuatan simplisia dan obat tradisional dalam bentuk sediaan kapsul. Hasil yang diperoleh dalam kegiatan ini adalah peserta antusias untuk memanfaatkan Kelakai sebagai obat tradisional, baik untuk dikonsumsi secara mandiri maupun sebagai produk yang bernilai ekonomis. Berdasarkan hasil kuisioner, terdapat peningkatan pengetahuan peserta tentang pemanfaatan Kelakai sebagai obat tradisional sebesar 68%.
Formulation of Wound Healing Hydrogel from 70% Ethanol Extract of Kelakai Roots (Stenochlaena palustris (Burm. F.) Bedd) with Polymer Combination of PVA/HPMC Forestryana, Dyera; Pebrianie, Shilpa; Ramadhan, Hafiz; Restapaty, Ratna
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 1 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.005291

Abstract

Kelakai root contains alkaloids, saponins, tannins, and flavonoids. This compound is known to have medicinal properties such as wound healing. The effectiveness of wound healing increased by using hydrogel to deliver the active substance. The use of polymers played a role in delivering the active substance. This study aimed to formulate hydrogels for wound healing with various concentrations of polyvinyl alcohol (PVA) and hydroxy propyl methyl cellulose (HPMC) K4M. Preparation of hydrogel by the solvent casting method used 0.2% Kelakai root extract. The physical characteristics of hydrogel investigated before and after the stability test included organoleptic, weight uniformity, thickness, pH, moisture content, and hedonic test of Kelakai roots extract hydrogel.  The optimum formula was tested for wound healing activity. The data obtained were then analyzed using Wilcoxon testswith p0.05 considered significant. Physically, Kelakai root extract hydrogel met the test requirements. The results of the wound-healing activity showed that the hydrogel extract of the Kelakai root was able to heal the wounds within seven days. There was a significant difference in wound healing time with p=0.014. The optimum formula obtained based on the stability test was F4 with a 1:4 ratio of PVA and HPMC. 
Co-Authors Amalia Khairunnisa, Amalia Andy Chandra, Muhammad Hadi, Ahmad Nur Hasymi, Liana Fitriani Indah Sayakti, Putri Jamaludin, Wahyudin Bin Kurdiansyah Muawiyyah, Walidatun Pebrianie, Shilpa Ramadhan, Hafiz Raudatunnisa Restapaty, Ratna Rusida, Esty Restiana Siti Helmyati Subareng, Ahmad Rizal Maulana Sutomo Sutomo Vebruati Vebruati, Vebruati Wiwin Tyas Istikowati