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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Sistem Komputer & Kecerdasan Buatan Law Research Review Quarterly Yumary: Jurnal Pengabdian kepada Masyarakat Jurnal Ilmiah Pharmacy Asian Australasian Neuro and Health Science Journal (AANHS-J) Pharmademica: Jurnal Kefarmasian dan Gizi Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Sains Medisina
Ramadhan, Hafiz
Unknown Affiliation
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Criminological Aspect on Case of Prostitution around Poncol Station Semarang Wicaksono, Andri Aditya; Saefudin, Yusuf Rizky; Ramadhan, Hafiz; Pangestu, Rico Alfian; Arifin, Ridwan
Law Research Review Quarterly Vol 6 No 1 (2020): L. Research Rev. Q. (February 2020) "Law, Democracy and Crime: How Society Respon
Publisher : Faculty of Law Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/lrrq.v6i1.31099

Abstract

Prostitution is an anti-social sexual deviation because it violates the norms of decency, norms of decency, customary norms and religious norms. This prostitution occurs in society in the form carried out by a group or individual in an organized manner consisting of pimps, the purpose of getting wages or rewards from those who have used their services. there are two parties namely PSK (Commercial Sex Workers) and masher men as customers. In the Criminal Code (KUHP) only regulates pimps, not yet regulating PSK and its customers. This has an impact on the development of prostitution in people's lives. Prostitution is regulated in Article 296 and Article 506. There are various factors behind the occurrence of this prostitution, such as economic factors caused by economic pressures and life burdens, there are also social factors such as the social environment, and family factors due to divorce or family problems. This study aims to find out what factors underlie the phenomenon of a CSW and analyze based on the perspective of criminological law. This research is located at Semarang Poncol Station on Jalan Imam Bonjol Semarang. This research uses an empirical and qualitative juridical approach. The results of the research and discussion show that the author obtained, among others, can be explained through the formulation that we discussed, namely: The characteristics that exist in the perpetrators of street prostitution, the impact on prostitution, technicalities in transactions between customers and prostitutes, and theories justify the existence of deviations in prostitution.
DAUN Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz SEBAGAI ANTI-Escherichia coli: STUDI IN SILICO DAN IN VITRO Ramadhan, Hafiz; Forestryana, Dyera; Jamaludin, Wahyudin Bin; Hadi, Ahmad Nur; Raudatunnisa
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 2023: Webinar Nasional & Call For Paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i3.1701

Abstract

This research was conducted to determine the potential of phytochemical contents in producing antibacterial activity from 70% ethanol extract of Balik Angin leaves  (Alphitonia incana (Roxb.) Teijsm . & Binn. ex Kurz) against Escherichia coli bacteria in silico and in vitro. In silico assay of 20 compounds contained in Alphitonia species against the DNA gyrase receptor using PLANTs. Anti-E.coli activity assay of Balik Angin leaves macerated with 70% ethanol solvent using the Well diffusion method. In silico studies show that β-Sitosterol, Stigmasterol, Rutin, Kaempferol 3-O-rutinoside, and Zizyphoiside C have binding energies with DNA gyrase that can exceed Ciprofloxacin. The antibacterial assay results at a highest concentration of 26.56 mg/ml can provide an average inhibitory zone diameter of 12.75 ± 0.2 mm with a minimum inhibitory concentration (MIC) of 1.66 mg/ml (5.87 ± 1.5 mm). The 70% ethanol extract of Balik Angin leaves has the potential as an anti-Escherichia coli, supported by the content of phytochemical compounds that can act as DNA gyrase inhibitors.
Skrining Fitokimia Dan Uji Aktivitas Antioksidan Infusa Daun Mundar (Garcinia forbesii King.) Menggunakan Metode DPPH (1,2-Diphenyl-1-Picrylhydrazyl) Muthia, Rahmi; Ramadhan, Hafiz; Arsyad, Zyrzasya Sofia Nara
Sains Medisina Vol 2 No 1 (2023): Sains Medisina
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Radikal bebas (oksidan) mencari dan menangkap elektron dari zat lain untuk menetralkan diri. Reaksinya menyebabkan terbentuknya senyawa abnormal yang dapat merusak sel-sel penting.  Salah satu sumber antioksidan alami adalah tumbuhan. Tumbuhan yang berpotensi sebagai antioksidan yaitu  Mundar (Garcinia forbesii King.). Penelitian ini bertujuan untuk mengetahui kandungan senyawa dan  mengetahui nilai IC50 infusa daun Mundar. Simplisia daun Mundar diekstraksi dengan metode infusa. Skrining fitokimia diujikan secara sederhana ditunjukkan dengan adanya dengan perubahan warna atau terbentuknya endapan. Uji aktivitas antioksidan dengan metode DPPH menggunakan Spektrofotometer UV-Vis. Pembanding yang digunakan kuersetin. Berdasarkan hasil skrining fitokimia infusa daun Mundar menunjukkan positif mengandung senyawa fenol dan flavonoid. Hasil uji aktivitas antioksidan infusa menggunakan konsentrasi 25, 50, 100, 150 dan 200 µg/mL  dengan rerata inhibisi masing-masing 24,575 ± 0,311, 28,679 ± 0,237, 33,880 ± 1,086, 36,054 ± 2,064 dan 41,176 ± 0,518 dengan nilai IC50 sebesar 297,9279 µg/mL. Kesimpulan dari penelitian ini adalah, infusa daun Mundar mengandung senyawa fenol dan flavonoid. Hasil uji kuantitatif aktivitas antioksidan infusa daun Mundar termasuk kategori antioksidan sangat lemah.
Pengembangan Sistem Informasi Enterprise Resource Planning Fiber to The Home pada Studi Kasus PT Trans Hybrid Communication Ramadhan, Hafiz; Zailani, Achmad Udin
Jurnal SISKOM-KB (Sistem Komputer dan Kecerdasan Buatan) Vol. 7 No. 1 (2023): Volume VII - Nomor 1 - September 2023
Publisher : Teknik Informatika, Sistem Informasi dan Teknik Elektro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47970/siskom-kb.v7i1.450

Abstract

Abstract—Dalam era globalisasi sekarang ini, perkembangan ilmu pengetahuan dan teknologi semakin pesat khususnya di bidang teknologi informasi. Sistem informasi telah menjadi kebutuhan beberapa perusahaan besar maupun kecil karena dapat mempermudah pekerjaan serta berpacu dengan perkembangan zaman. PT Trans Hybrid Communication menghadapi banyak tantangan dalam mengelola sumber daya perusahaan, seperti mengelola sumber daya manusia, manajemen operasional dan manajemen keuangan. Dalam tugas akhir ini, penulis menggunakan metode pengembangan perangkat lunak berbasis Agile yang merupakan salah satu dari model Software Development Life Cycle (SDLC). Penelitian ini bertujuan untuk mengembangkan sistem informasi Enterprise Resource Planning (ERP) untuk PT Trans Hybrid Communication, dengan fokus khusus pada layanan Fiber To The Home (FTTH). Enterprise Resource Planning (ERP) adalah perangkat lunak utama dari perusahaan yang bekerja untuk mengintegrasikan informasi yang ada di semua bidang bisnis yang memiliki tujuan untuk dapat merencanakan dan mengelola semua sumber daya yang tersedia bagi suatu perusahaan sehingga semua bisnis area dalam perusahaan bisa berjalan dengan baik. Pengembangan sistem informasi ERP FTTH membantu PT Trans Hybrid Communication mengoptimalkan penggunaan sumber daya, meningkatkan efisiensi, efektivitas operasional, dan memperbaiki pengambilan keputusan. Dapat terlihat dari tanggapan reaksi pengguna, dengan persentase rata – rata 87,8% yang sangat setuju, bahwa penggunaan Sistem Informasi Enterprise Resource Planning (ERP) memiliki dampak yang signifikan. Keywords — Sistem Informasi, Enterprise Resource Planning, Fiber To The Home, Pengembangan Sistem
Systematic Review of the Effectiveness of Using iPSC in Spinal Cord Injury Ibrahim, Sabri; Ramadhan, Hafiz
Asian Australasian Neuro and Health Science Journal (AANHS-J) Vol. 4 No. 3 (2022): AANHS Journal
Publisher : Talenta Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/aanhsj.v4i3.10124

Abstract

Damage to the spinal cord is the pathological condition known as spinal cord injury (SCI) or spinal cord injury. This ailment, which not only causes neurological impairments but also places a significant psychological and social burden on patients, has grown to be one of the most challenging worldwide health issues. A successful stem cell-based treatment has just been created and could be the answer to this medical issue. It has been demonstrated that iPSC-dNSC stem cells are efficient at both reducing post-traumatic inflammatory conditions and kicking off neuronal cell regeneration at the location of SCI lesions. The aim of this study to investigate the the effectiveness of using iPSC in spinal cord injury. This study used the literature review method by discovering articles using the search engine Google Scholar, and PubMed. According to the search results, 413 articles were obtained in accordance with the title of the study, but 8 articles met the inclusion criteria in this study. The findings of this study showed that the iPSC methodology was applied, as well as the advantages and results of the procedure. Using iPSCs to treat SCI is still challenging and needs additional investigation.
Early Postoperative Serum Sodium Level and Urine Output Volume Profile after Endoscopic Endonasal Transsphenoidal Surgery in Macroadenoma Pituitary Tumor Ramadhan, Hafiz; Syafitri, Adinda; Irsyad, Muhammad Ari; Nasution, Muhammad Deni
Asian Australasian Neuro and Health Science Journal (AANHS-J) Vol. 5 No. 2 (2023): AANHS Journal
Publisher : Talenta Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/aanhsj.v5i2.12347

Abstract

Introduction: Surgery is still the initial treatment of choice to for the majority of date with pituitary tumors. One of the most commonly performed minimally invasive neurosurgical procedures is transsphenoidal endoscopic endonasal surgery (ETS) and microscopic transsphenoidal surgery (MTS), used commonly for the resection of pituitary tumors. Neurosurgical operations for pituitary and suprasellar tumors may result in postoperative complications due to the crucial anatomical location of these tumors. The resulting postoperative complications can manifest as anterior or posterior pituitary dysfunction, particularly sodium disturbances, due to the changes in antidiuretic hormone (ADH) secretion, which remains one of the most frequent postoperative reasons for hospital readmission. Method: The aim of this study is to describe and determine the frequency distribution of patient characteristics who underwent endoscopic endonasal transsphenoidal resection of pituitary adenoma at Universitas Sumatera Utara Hospital between 2021 and 2022. Result: The findings of this study showed the frequency distribution of patient characteristics who underwent endoscopic endonasal transsphenoidal resection and postoperative sodium serum level profile as well as postoperative urine output profile. Discussion: The discussion section briefly discusses the findings and their implications. It mentions the high prevalence of headache and visual deficits among the patients, which aligns with previous studies. It also provides an overview of normal water balance and the pathophysiology of water balance disorders after pituitary surgery.  
Formulasi Dispersi Padat Pentagamavunon-0 (PGV-0) dalam Bentuk Sediaan Hidrogel dengan Kombinasi Basis Polimer Kitosan-Agar-PVP Forestryana, Dyera; Ramadhan, Hafiz
JSFK (Jurnal Sains Farmasi & Klinis) Vol 7 No 1 (2020): J Sains Farm Klin 7(1), April 2020
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.7.1.66-75.2020

Abstract

Pentagamavunon-0 (PGV-0) merupakan analog kurkumin dengan stabilitas yang lebih baik. PGV-0 memiliki kapasitas sebagai antioksidan, namun mengalami metabolisme lintas pertama pada pemberian secara oral. Untuk meningkatkan efektivitasnya, PGV-0 dibuat dalam bentuk sediaan transdermal. PGV-0 memiliki kelarutan terbatas di dalam air sehingga dibuat ke dalam sistem dispersi padat dengan polyvinylpyrrolidone (PVP) untuk meningkatkan kelarutannya. Penelitian ini bertujuan untuk membuat formula dispersi padat PGV-0/PVP ke dalam matriks hidrogel. Sediaan matriks dibuat 3 formula dengan menggunakan basis polimer kitosan-agar-PVP dengan memvariasikan jumlah penggunaan PVP. Evaluasi sediaan meliputi organoleptis, bobot, ketebalan, pH, moisture content, moisture uptake, daya lipat dan drug content. Uji penetrasi in vitro dilakukan dengan menggunakan sel difusi Franz. Formula optimum yang diperoleh yaitu hidrogel dispersi padat PGV-0/PVP dengan perbandingan 1:1 (F2B) yang memiliki moisture content sebesar 1,2% ± 0,28% dan nilai fluks sebesar 121,6227μg cm-² jam-¹
The Effect of Different Soxhlet Extraction Solvents Towards AntiPropionibacterium acnes Activity of Balik Angin Leaves (Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz) : Pengaruh Perbedaan Pelarut Ekstraksi Soxhlet Terhadap Aktivitas AntiPropionibacterium acnes dari Daun Balik Angin (Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz) Ramadhan, Hafiz; Forestryana, Dyera; Subareng, Ahmad Rizal Maulana; Vebruati, Vebruati
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 11 No. 1 (2025): (March 2025)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2025.v11.i1.16634

Abstract

Background: Acne is a skin infection that may be induced by Propionibacterium acnes. Treatment of acne infection from natural ingredients native to Kalimantan such as Balik Angin or Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz can be an alternative therapy. Prior research indicates that leaves macerated with methanol and 70% ethanol solvents can inhibit the growth of P. acnes in the medium category with a Minimum Inhibitory Concentration (MIC) of 3.2%. Objectives: The research purpose is to compare the effect of the different solvents of soxhlet extraction on the antibacterial activity of Balik Angin leaves in inhibiting the growth of P. acnes. Material and Methods: Balik Angin leaves were extracted using the Soxhlet with two different solvents, which were methanol and 70% ethanol, then followed by phytochemical screening. The antibacterial activity assay was carried out by using well diffusion with each sample concentrations of 25.6%; 12.8%; 6.4%; 3.2%; 1.6%; 0.8%; 0.4%; and 0.2%. Results: Both extracts contained the same phytochemical groups, which were phenols, flavonoids, alkaloids, tannins, saponins, and triterpenoids. The antibacterial activity test results showed that both extracts had the same MIC of 0.8%. however, the 70% ethanol extract of Balik Angin leaves was able to provide a larger inhibition diameter average of 9.61±0.35 mm compared to the methanol extract of 9.20±0.22 mm. Nonetheless, there was no significant difference (p>0.05) between both concentrations, when compared to the range of 1.6-25.6%. Conclusions: The conclusion of this research is that differences in Soxhlet extraction solvents in Balik Angin leaves can affect its activity as an anti-Propionibacterium acnes agent.
PARADIGMA MASYARAKAT TENTANG KHASIAT DAUN BALIK ANGIN (Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz) SEBAGAI ANTIOKSIDAN Ramadhan, Hafiz; Akbar, Depy Oktapian; Ramadhani, Syahrizal; Yanie, Akhmad; Fitriah, Rahmayanti; Alfi, Muhammad
Jurnal Ilmiah Pharmacy Vol 12, No 1 (2025)
Publisher : Sekolah Tinggi Kesehatan Al-Fatah Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52161/jiphar.v12i1.632

Abstract

Pentingnya pemahaman masyarakat tentang tanaman obat, khususnya daun Balik Angin (Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz), yang diketahui memiliki potensi sebagai sumber antioksidan. Tanaman ini sering digunakan dalam pengobatan tradisional, namun pengetahuan masyarakat tentang manfaatnya masih perlu ditingkatkan. Tujuan penelitian ini adalah untuk mengetahui gambaran karakteristik masyarakat di Kawasan Bukit Tahura Desa Mandiangin Timur, Kecamatan Karang Intan, dan untuk mengetahui paradigma masyarakat tentang daun Balik Angin sebagai antioksidan di kawasan tersebut. Metode yang digunakan adalah survei dengan melibatkan 100 responden yang dipilih secara purposive sampling. Data dikumpulkan melalui kuesioner yang mengukur pengetahuan dan sikap masyarakat terhadap daun Balik Angin. Hasil penelitian menunjukkan bahwa karakteristik masyarakat sebagian besar adalah perempuan sebanyak 60 orang (60%), dengan rentang umur 37-47 tahun sebanyak 42 orang (42%). Sebagian besar responden bekerja sebagai wirausaha atau pedagang sebanyak 30 orang (30%), dan pendidikan sebagian besar adalah SMA sebanyak 46 orang (46%). Selain itu, 84% responden memiliki pengetahuan baik mengenai manfaat daun Balik Angin sebagai antioksidan. Kesimpulan dari penelitian ini adalah bahwa masyarakat di Kawasan Bukit Tahura memiliki paradigma positif terhadap penggunaan daun Balik Angin, namun masih diperlukan edukasi lebih lanjut mengenai cara pengolahan pemanfaatan tanaman secara optimal.
Penerapan Simple Water Filter pada Masyarakat Desa Benua Raya, Kecamatan Bati-Bati, Kabupaten Tanah Laut Ramadhan, Hafiz; Forestryana, Dyera; Hasymi, Liana Fitriani; Sutomo, Sutomo; Khairunnisa, Amalia; Istikowati, Wiwin Tyas
Yumary: Jurnal Pengabdian kepada Masyarakat Vol. 5 No. 3 (2025): Maret
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/yumary.v5i3.3660

Abstract

Purpose: The aim of this community service is a form of disaster preparedness to prevent health problems through the implementation of simple water filters in Benua Raya Village, Bati-Bati District, Tanah Laut Regency. Methodology: Activities were carried out by implementing Clean and Healthy Living Behavior (PHBS) counseling and training on making simple water filters for community mothers and Posyandu cadres with a total of 52 people on September 18th, 2024. Results: The activity results showed that participants knew and understood the importance of PHBS, especially using clean and suitable water for daily life and when affected by natural disasters as a form of disease prevention. The percentage of knowledge before the activity was 80.77%-94.23%, which increased after the activity to 96.15%-100%. The level of knowledge and skills of participants in making simple water filters also increased from 44.23%-48.08% to 88.46%-94.23%. Conclusions: This activity concludes that counseling and training on making simple water filters can increase the awareness of the people of Benua Raya Village to implement PHBS and can be one of the family preparedness efforts in obtaining clean water when a flood disaster occurs. Limitations: The activity was only attended by Posyandu cadres and housewives. Contribution: The counseling, education, and training activities for the Benua Raya Village community need to be carried out consistently because they contribute to increased awareness of Clean and Healthy Living Behavior.
Co-Authors Achmad Udin Zailani Adinda Syafitri, Adinda Akbar, Depy Oktapian Alfi, Muhammad Amalia Khairunnisa, Amalia Arsyad, Zyrzasya Sofia Nara Febriani, Reva Aura Forestryana, Dyera Hadi, Ahmad Nur Hasymi, Liana Fitriani Ibrahim, Sabri Irsyad, Muhammad Ari Jamaludin, Wahyudin Bin Maharani, Nessa Astika Nasution, Muhammad Deni Pambudi, Didik Rio Pangestu, Rico Alfian Putri Indah Sayakti Rahmayanti Fitriah Rahmi Muthia Ramadhani, Syahrizal Raudatunnisa Ridwan Arifin Saefudin, Yusuf Rizky Siti Anisa Subareng, Ahmad Rizal Maulana Sutomo Sutomo Vebruati, Vebruati Wicaksono, Andri Aditya Wiwin Tyas Istikowati Yanie, Akhmad