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Jurnal Farmasi Sains dan Komunitas

JFSK
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Published by Universitas Sanata Dharma

ISSN : 16935683 EISSN : 25277146 DOI : https://doi.org/10.24071/

Core Subject : Health,

Medicine & Pharmacology

Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community / J Pharm Sci Community) firstly published in 2003, is a peer-reviewed, open access scientific journal that publishes research articles, review articles, as well as short communication in various pharmaceutical fields, including Pharmaceutical Technology and Pharmaceutics, Pharmaceutical Analysis, Medicinal Chemistry, Pharmacology and Toxicology, Pharmaceutical Biology, Community Pharmacy, and Clinical Pharmacy.

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 9 Documents

Search results for , issue "Vol 9, No 2 (2012)" : 9 Documents clear

OPTIMASI FORMULA TABLET EFFERVESCENT EKSTRAK RIMPANG JAHE MERAH (Zingiber officinale Roxb. Var rubrum) Henny Dwi Arini; Lannie Hadisoewignyo
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 9, No 2 (2012)
Publisher : Sanata Dharma University

Abstract:This study aims to determine the effect of sodium citrate and fumaric acid as a source ofacid in the tablet formula effervescent red ginger rhizome extract (Zingiber officinale Roxb. varrubrum) and obtain the optimum composition of the formula that has the physical properties oftablet effervescent red ginger rhizome extract (Zingiber officinale Roxb. var rubrum) that meetthe requirements. Optimization techniques used in research is a method of factorial design withtwo factors and two levels of sodium citrate and fumaric acid with low levels of 80 mg, and highlevels of 120 mg. Responses were observed to obtain optimum formula is hardness, friability, andthe soluble tablet (effervescent time). The result is the concentration of sodium citrate andfumaric acid did not significantly affect tablet hardness effervescent. Meanwhile, that issignificantly influences the friability and time effervescent soluble tablets. However, theinteraction between sodium citrate and fumaric acid did not significantly affect the hardness,friability, and the soluble tablet effervescent red giinger extract. Optimum formula tabletsobtained effervescent namely sodium citrate 80 mg and 80 mg of fumaric acid with 6,529 kgfresponse tablet hardness, tablet friability 0,1354%, and effervescent time of 5,98 minutes.Key words : Red ginger, effervescent tablet, factorial design

PENGARUH PEMBERIAN MADU HUTAN TERHADAP PROLIFERASI LIMFOSIT PADA HEWAN UJI TIKUS JANTAN GALUR WISTAR Kartika Sari Senas; Yunita Linawati
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 9, No 2 (2012)
Publisher : Sanata Dharma University

Abstract: Forest honey is produced by wild bees by taking nectars from several kinds of plant.One of active chemicals contained within honey is flavonoid. It is believed as animmunomodulator due to it has role in fighting against free radicals and increasing body immunesystem against disease infection. This research aimed to understand the influences of foresthoney administration to the lymphocyte proliferation on male mice Wistar family. This researchis a pure, experimental with one way, random research design. Total of 20 rats was divided into 4groups. Each group was given honey forest with dose of 0,27; 0.54; 1.08 mL/200 g BW, andnegative control group was given aquadest 2.5 mL/200 g BW. The lymphocyte proliferation ismeasured from the amount of lymphocyte based on Optical Density (OD) values, the read onELISA reader at the wavelength of 550 nm. The result shown that the administration of foresthoney has effect on significance increase the lymphocyte proliferation (p0.05) than negativecontrol on male mice Wistar family.Key words : Foresthoney, lymphocyte proliferation, immunomodulator

FORMULASI TABLET EFFERVESCENT EKSTRAK DAUN SINGKONG (Manihot utillissima Pohl.) DAN EKSTRAK HERBA PEGAGAN (Centella asiatica (L.) Urban) Serevino L. Ambuk; Agatha Budi Susiana Lestari
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 9, No 2 (2012)
Publisher : Sanata Dharma University

Abstract: Asiaticoside compound in gotu kola extract (Centella asiatica (L.) Urban) and rutincompound in extract of cassava leaves (Manihot utillissima Pohl.) has been proofed fordegenerative diseases treatment. Effervescent tablet was chosen to facilitate the herb gotu kolaextract and cassava leaves extract because of fresh sensation and easy to use. The aims of thisstudy was investigated the effect of tartaric acid, sodium bicarbonate, their interactions, anddiscovered the optimum composition in order to producing effervescent tablets for qualityrequirements. Quality requirements term in this study were the moisture content of granule, tablethardness, friability of tablets, dissolution time. The results showed that tartaric acid significantlyinfluenced moisture content of granules, tablets friability, dissolution time of tablets, whilesodium bicarbonate significantly affected tablets hardness. Based on super imposed contourplot, the optimum composition for effervescent tablets was at the level 1000 mg tartaric acid and1120 mg sodium bicarbonate.Keywords: gotu kola extract, cassava leaves extract, effervescent tablet

UJI AKTIVITAS ANTIOKSIDAN DAN PENETAPAN KADAR FENOLAT TOTAL FRAKSI AIR DAUN KETAPANG (Terminalia catappa L.) DENGAN METODE DPPH (2,2-diphenyl-1-picrylhydrazyl) DAN METODE FOLIN-CIOCALTEU Aldo Sahala; C.J. Soegihardjo
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 9, No 2 (2012)
Publisher : Sanata Dharma University

Abstract: The aqueous fraction of methanolic extract of Ketapang (Terminalia catappa L.). wasinvestigated for its DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical scavenger activity andthe total amount of phenolic using Folin-Ciocalteu method. It was found that the aqueousfraction of methanolic extract of Ketapang tested showed significant DPPH free radicalscavenging with IC50 value 34,071 0,424 g/mL. The total phenolic amount was 5.429 0.110mg equivalent mass value of gallic acid per gram aqueous fraction of the methanolic extract ofketapang leaves.Keywords: aqueous fraction, methanolic extract, Terminalia catappa, DPPH, total phenolic.

HEALTH SEEKING BEHAVIOR DI KALANGAN MASYARAKAT URBAN DI KOTA YOGYAKARTA Aris Widayati
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 9, No 2 (2012)
Publisher : Sanata Dharma University

Abstract : Research presented in this article investigated health seeking behavior among peoplein an urban area of Yogyakarta City Indonesia. The research was a cross-sectional surveyinvolved adults in Yogyakarta City who were selected using a cluster random samplingtechnique. Sample size was 640 respondents. Data were collected using a pre-testedquestionnaire during March to May 2010. Data were analyzed using descriptive statistics, Chisquare tests, and Logistic regression. A total of 559 questionnaires were completed, resulted in90% of response rate. Mostly respondents stated that they had one to three medical complaintswithin a month (51% of 559). The most popular health seeking behavioris a combination betweenself-care and consultation to health care providers (41%). Other options are self-care (36%),consultation to public health care centre (16%), and consultation to private health care (5%).Among the socio-demographic and economic characteristics, marital status is the only factorthat significantly correlated with health seeking behavior. Based on the results it can berecommended that programs for improving health behavior should consider self-care, includingno medication and self medication with modern and herbal/traditional medicines. The role offamily members (e.g. spouse) should also be considered as an important factor of health relatedbehavior.Keywords : Health seeking behavior

STRATEGI PEMERIKSAAN LABORATORIUM ANTIHIV Woro Umi Ratih
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 9, No 2 (2012)
Publisher : Sanata Dharma University

Abstract: Human Immunodeficiency Virus (HIV) infection has increased significantly in recentyears. The virus continues to spread in all the countries. There are some strategies and programsto control HIV infection by activities carried out individually or groups. HIV testing technologiesare needed for use in diagnostic testing. Data from diagnostic testing may be used as a source ofsurveillance information. Rapid Diagnostic Test (RDT) and ELISA with various reagents are thecurrent diagnostic testing procedures. It is important to select reagents to get the good results.Keywords : HIV, testing, diagnostic

ISOLASI DAN IDENTIFIKASI SENYAWA ALKALOID BUAH MAHKOTA DEWA (Phaleria macrocarpa (Scheff.) Boerl) SECARA SPEKTROFOTOMETRI UV-Vis DAN IR SERTA UJI TOKSISITAS AKUT TERHADAP LARVA Artemia salina Leach Christina Astutiningsih; Frida Nuzulia; Agus Suprijono
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 9, No 2 (2012)
Publisher : Sanata Dharma University

Abstract: Fruit Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl) contains alkaloid, tannin,saponin, flavonoid, terpenoid dan lignin. The aim of this study was to elucidate compound fromMahkota Dewa based on the analyses on spectrophotometry UV-Vis, IR and to evaluate thecompound in the Brine Shrimp Lethality Test. On IR spectra revealed the presence of alkaloidamin primer. The isolated alkaloid compound was found to be toxic to brine shrimp with LC5033.8932 ?g/ml.Keywords: alkaloid, Mahkota Dewa, toxicity, Artemia salina Leach

REVIEW: PELUANG MAHKOTA DEWA SEBAGAI ANTIKANKER Phebe Hendra
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 9, No 2 (2012)
Publisher : Sanata Dharma University

Abstract: In order to be used in formal health care systems, medicinal plants have to be safe anddisplay promising pharmacological effects. Mahkota dewa is well known as a traditionalmedicine in Indonesia. In folk medicine, its fruits and leaves are used to relief cancer, impotency,hypoglycemic, hypotensive, antirheumatic, liver and kidney disorders and skin disorders.According to pharmacology and toxicology studies especially on cytotoxic effects, mahkota dewahas anticancer activity. However, further studies will be required to establish the cell target foranticancer treatment.Key words: mahkota dewa, anticancer, cytotoxic

PEMAHAMAN MASYARAKAT DESA PERERENAN, KECAMATAN MENGWI, KABUPATEN BADUNG, BALI TENTANG BOREH-ANGET Titien Siwi Hartayu; Ketut Ary Widiasih
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 9, No 2 (2012)
Publisher : Sanata Dharma University

Abstract : Boreh-anget is one of Bali traditional medicines used by the ancient people ofBali to warm their body and it is believed that Boreh-anget could be used for pain relieves,improving blood circulation reduces rheumatic pain, and fever. This study is aimed to identifyknowledge of recent generation in Bali about Boreh-anget, including what are the ingredientsof it, how to make it, how to use it, and what benefit by using it. This study was conducted atPererenan village, Mengwi, Badung Bali where is most all of people there using Boreh-anget.This study is non-experimental, descriptive qualitative approach, using purposive sampling.There are 78 participants with age ranging form 26 60 years old involve in this study. Dataare collected using questionnaires and supported by in-depth interview among a viewparticipants, and then the data are analyzed using enumerative methods. Results of the studyshow that 76.3% of participants knew about the ingredients of Boreh-anget, 92.6% ofparticipants knew how to make Boreh Anget, 80.3% of participants knew how to use Borehanget and 78.0% of participants knew the benefit of using Boreh-anget. Conclusions of thisstudy is that recent generation in Pererenan, Mengwi, Badung, Bali still have a high level ofknowledge about Boreh-anget.Keyword: Boreh-anget, tradisional-medicines, Bali, traditional ingredient

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Florentinus Dika Octa Riswanto

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editorial.jpsc@usd.ac.id

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editorial.jpsc@usd.ac.id

Editorial Address
Faculty of Pharmacy, Universitas Sanata Dharma, Indonesia

Location
Kab. sleman,

Daerah istimewa yogyakarta

INDONESIA

Abstract

Abstract

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Florentinus Dika Octa Riswanto

Contact Email editorial.jpsc@usd.ac.id

Phone -

Journal Mail Official editorial.jpsc@usd.ac.id

Editorial Address Faculty of Pharmacy, Universitas Sanata Dharma, Indonesia

Location Kab. sleman, Daerah istimewa yogyakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Florentinus Dika Octa Riswanto

Contact Email
editorial.jpsc@usd.ac.id

Phone
-

Journal Mail Official
editorial.jpsc@usd.ac.id

Editorial Address
Faculty of Pharmacy, Universitas Sanata Dharma, Indonesia

Location
Kab. sleman,

Daerah istimewa yogyakarta

INDONESIA