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ISOLASI DAN IDENTIFIKASI SENYAWA ALKALOID BUAH MAHKOTA DEWA (Phaleria macrocarpa (Scheff.) Boerl) SECARA SPEKTROFOTOMETRI UV-Vis DAN IR SERTA UJI TOKSISITAS AKUT TERHADAP LARVA Artemia salina Leach Christina Astutiningsih; Frida Nuzulia; Agus Suprijono
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 9, No 2 (2012)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (659.836 KB) | DOI: 10.24071/jpsc.0072

Abstract

Abstract: Fruit Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl) contains alkaloid, tannin,saponin, flavonoid, terpenoid dan lignin. The aim of this study was to elucidate compound fromMahkota Dewa based on the analyses on spectrophotometry UV-Vis, IR and to evaluate thecompound in the Brine Shrimp Lethality Test. On IR spectra revealed the presence of alkaloidamin primer. The isolated alkaloid compound was found to be toxic to brine shrimp with LC5033.8932 ?g/ml.Keywords: alkaloid, Mahkota Dewa, toxicity, Artemia salina Leach
PERBEDAAN PENGARUH LAMA PENYIMPANAN LARUTAN SUSU BUBUK FULL CREAM DAN LARUTAN SUSU KENTAL MANIS TERHADAP KADAR GLUKOSA Risha Fillah Fithria; Agus Suprijono; Maywan Hariono
Jurnal Ilmu Farmasi dan Farmasi Klinik Jurnal Ilmu Farmasi & Farmasi Klinik Vol.9 No.2 Desember 2012
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (67.167 KB) | DOI: 10.31942/jiffk.v9i2.863

Abstract

ABSTRACTMilk and the products which have expired usually be thrown by people immediately.However, those are still having lactose content even do not like as much as a fresh milk. Lactose content of milk and the expired products can be extracted and then hydrolized to yield glucose and galactose. The glucose content can be determined, so it will give information about ehancing value of expired milk that the glucose content can be developed furthermore to larger scale (industrial scale). This research was aimed to know influence of storage duration toward glucose content of fresh milk, full cream milk powder solution and sweet concentrate milk solution, and comparison of glucose content for each product. Research object was glucose content of fresh milk, full cream milk powder solution and sweet concentrate milk solution which was store for 0, 1, 2, 3, 4 and 5 days with gravimetric methode and determined by Friedman test; comparison of glucose content for each product determined by Anova because its distribution are normal and its variation are homogen, or by Kruskal-Wallis because its distribution are unnormal and its variation are unhomogen using SPSS version 15.0 with level of statistic confidence 99%. The result showed that the storage duration was influenced toward glucose content of fresh milk, full cream milk powder solution and sweet concentrate milk solution significantly and there are significance difference of glucose content for each products with the manipulation on storage duration.Key words : storage duration, glucose, fresh milk, full cream milk powder solution and sweet concentrate milk solution
KRIM TABIR SURYA DARI KOMBINASI EKSTRAK SARANG SEMUT (Myrmecodia pendens Merr & Perry) DENGAN EKSTRAK BUAH CARICA (Carica pubescens) SEBAGAI SPF Suwarmi Suwarmi; Agus Suprijono
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Perkembangan Terbaru Pemanfaatan Herbal Sebagai Agen Preventif Pada Tera
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (274.64 KB) | DOI: 10.31942/jiffk.v0i0.1210

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ABSTRAK Sarang semut (Myrmecodia pendens Merr & Perry) merupakan tanaman yang secara empirik banyak dimanfaatkan sebagai tanaman obat terutama karena kandungan flavonoid yang berfungsi sebagai antioksidan, demikian juga dengan carica (Carica pubescens) merupakan buah dengan kandungan vitamin C tinggi. Antioksidan mampu menghambat reaksi oksidasi serta menetralkan radikal bebas yang terbentuk akibat paparan sinar UV. Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh kombinasi ekstrak kering buah carica dan ekstrak kental sarang semut terhadap karakteristik fisik sediaan krim tabir surya dan nilai SPF dengan konsentrasi formula (carica : sarang semut) yaitu FI (20%:0%); FII (0%:20%); FIII (10%:10%); & FIV (0%:0%) serta pengaruh lama penyimpanan terhadap kestabilan. Ekstrak kering buah carica diperoleh dengan menggunakan alat Freeze Dryer dan ekstrak kental umbi sarang semut diperoleh dengan metode remaserasi dengan pelarut etanol 70%. Sediaan krim tabbir surya diuji karakteristik fisik (meliputi: uji organoleptis, uji pH, uji daya lekat, uji daya sebar, uji viskositas, uji tipe emulsi, homogenitas). Efektivitas sediaan krim tabir surya dilakukan dengan pengujian SPF. Hasil penelitian menunjukkan bahwa perbedaan komposisi dalam sediaan krim tabir surya dapat mempengaruhi karakteristik fisik dan nilai SPF sediaan, serta memberikan hasil yang stabil selama penyimpanan. Nilai SPF tertinggi terdapat pada formula II sebesar 1,448-1,469. Kata kunci: carica, krim, sarang semut, SPF, tabir surya.
MINYAK NILAM (Patchouli alcohol) SEBAGAI ANTIOKSIDAN DENGAN METODE DPPH (1,1-difenil-2-pikrilhidrazil) Agus Suprijono; Yoel Gunawan; Ariani Hesti Wulan
Jurnal Ilmu Farmasi dan Farmasi Klinik Jurnal Ilmu Farmasi & Farmasi Klinik Volume 12 No. 1 Juni 2015
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (209.115 KB) | DOI: 10.31942/jiffk.v12i1.1400

Abstract

ABSTRACTAlong with the rapid flow of information and globalization, led to the lifestyle of modern society is also becoming more and more advanced. But this was not accompanied by increased quality of public health. Lifestyle such as this may result in exposure to free radicals degna. Antioxidants are compounds that can inhibit the oxidation of free radicals, so it will form a more stable compound. Oil Patchouli (Patchouli oil) contains patchouli alcohol which have antioxidant activity. The rate is determined by the quality of patchouli oil patchouli alcohol content therein. The purpose of this research is to show the antioxidant activity of patchouli oil and standard determine differences in activity with BHT, as well as to determine the effective concentration expressed in EC50 values by using DPPH method. The examination was conducted by using the test solution at a concentration of 5%, 10%, 15%, 20% and 25%. The process to obtain the patchouli oil is done by means of steam distillation of the dried herb patchouli. Identification test to determine the quality of the oil produced by TLC test and also qualitative test to determine the antioxidant activity. From the research it can be seen that the average value of EC50 for patchouli oil sample is equal to 19.95%, while 11.93% of standard BHT. Based on these results, concluded that the antioxidant activity in patchouli oil, and there are significant differences in antioxidant activity between standard patchouli oil with BHT.Keywords: patchouli oil, patchouli alcohol, anti-oxidant, DPPH.
PENGARUH PEMBERIAN EKSTRAK ETANOL DAN ISOLAT FLAVONOID TEH OOLONG (Camellia sinensis [L.] O. K) TERHADAP PENURUNAN KADAR GLUKOSA SECARA IN VITRO Agus Suprijono; Dian Ayu Kusumaningrum; Lia Kusmita
Prosiding Seminar Nasional Unimus Vol 1 (2018): Hilirisasi & Komersialisasi Hasil Penelitian dan Pengabdian Masyarakat untuk Indonesia
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Ekstrak etanol dan isolat daun teh oolong (Camellia sinensis [L.] O. K) diduga mengandung senyawa-senyawa fenolik terutama flavonoid. Flavonoid  merupakan salah satu kandungan tanaman terbesar di alam yang dapat berpotensi untuk mengatasi diabetes melitus.Diabetes melitus adalah suatu kelainan metabolik kronik yang ditandai dengan kadar glukosa darah yang melebihi nilai normal (hiperglikemia) akibat tubuh kekurangan insulin baik absolut maupun relative. Tujuan dari penelitian ini  untuk mengetahui  pengaruh pemberian, ada tidaknya perbedaan aktivitas, serta konsentrasi maksimal ekstrak etanol dan isolatflavonoid daun teh oolong (Camellia sinensis [L.] O. K)  terhadap penurunan kadar glukosa secara in vitro. Metode ekstraksi yang digunakan dalam penelitian ini adalah metode maserasi dengan menggunakan pelarut etanol 70%. Isolasi senyawa flavonoid dilakukandengan menggunakan metode kromatografi kolom. Penetapan kadar  glukosa dilakukan dengan menggunakan metode Nelson – Somogy. Ekstrak etanol dan isolat flavonoid masingmasing dibuat seri konsentrasi 60, 80, 100, 120, dan 140 ppm. Struktur flavonoid dari daun teh oolong yang dapat menurunkan kadar glukosa secara in vitro senyawa turunan flavonol dengan rumus 6, 7 dihidroksi flavonol. Hasil persentase penurunan kadar glukosa setelah penambahan ekstrak etanol berturut-turut sebesar 59,30%, 63,95%, 72,27%, 59,73%, 56,29%, sedangkan setelah penambahan isolat flavonoid berturut-turut yaitu 40,88%,46,35%, 50,19%, 58,09%, 60,95%. Dari data yang diperoleh dalam penelitian, kemudian diuji menggunakan uji Anava dua jalan dan uji t. Hasil uji statistika menunjukkan bahwa ada perbedaan bermakna nilai persen penurunan kadar glukosa secara in vitro antara kelompokkonsentrasi ekstrak etanol dan isolat flavonoid.
Teachers' Subjective Construction in Natural and Social Science Subjects Yoga Dhamantara; Agus Suprijono; Neni Mariana
JURNAL PENDIDIKAN DAN PENGEMBANGAN MANUSIA Vol 9 No 2 (2024): Education and Human Development Journal
Publisher : Universitas Nahdatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ehdj.v9i3.5534

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The implementation of the integration of the Natural Sciences and Social Sciences (IPAS) curriculum in elementary schools is one of the significant changes in the Indonesian education curriculum, which is expected to improve the quality of education and prepare students to face future challenges. However, the implementation of IPAS also faces a number of obstacles and challenges that need to be overcome. This research aims to identify the main obstacles faced by schools in implementing IPAS. The research will use a mixed methods approach combining qualitative and quantitative methods. The data we collect will be analyzed using statistical software and qualitative analysis techniques to identify key patterns and findings. The results of this research will provide valuable insights that can support efforts to improve basic education in Indonesia, and bridge the gap between learning policies and practices in elementary schools. In future research, it is hoped that it can sharpen the discussion of science and science learning in elementary schools which not only discusses the material but also approaches to learning.
Pengembangan Buku Teks Berbasis Budaya Lokal (Lego-Lego) Sebagai Sumber Belajar IPS Untuk Pengutan Pendidikan Karakter Siswa di Sekolah Dasar Jon Abraham Lalang Yame; Waspodo Tjipto Subroto; Agus Suprijono
EDUKASIA Jurnal Pendidikan dan Pembelajaran Vol. 3 No. 3 (2022): Edukasia: Jurnal Pendidikan dan Pembelajaran
Publisher : LP. Ma'arif Janggan Magetan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62775/edukasia.v3i3.192

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Indonesia is experiencing a crisis of love for the nation influenced by the lifestyle and culture of western nations who enter Indonesia. The key to this crisis lies in human resources. For this reason, it is necessary to improve the quality of human resources through the formation of national character. The occurrence of conflicts in Alor Regency is mostly caused by minor problems, which is due to the unfavorable character of the community. Efforts to prevent all forms of horizontal conflict that occur in society through local cultural values as a strengthening of character education in the life of the Alor community. One is the Lego-Lego culture. Lego is a social capital that has been inherited by the ancestors of the Alor community. The lego-lego dance contains a very deep meaning through the values implied in poetry or rhymes which are not only useful for fellow people in an effort to strengthen relationships between individuals, build unifying values, form community character, and the government. In relation to the need for teaching materials in the form of text books based on culture and local wisdom in Alor, it is necessary to study the development of local culture and wisdom, namely Lego-lego as social studies learning resources to improve student character education. This study uses a development method with a Four-D model consisting Define, Design, Develop and Disseminate with data collection techniques using observation, questionnaires and interviews. Data analysis was carried out descriptively qualitatively and quantitatively. The results of the study indicate that textbook teaching materials are very significant in improving students' abilities and forming student character through social studies learning in elementary schools related to local culture of Lego-lego.
Implementasi Pembelajaran Berdiferensiasi Dalam Kurikulum Merdeka Pada Mata Pelajaran Sejarah Di SMA Negeri 22 Surabaya Sindy Dwi Jayanti; Agus Suprijono; M. Jacky
EDUKASIA Jurnal Pendidikan dan Pembelajaran Vol. 4 No. 1 (2023): Edukasia: Jurnal Pendidikan dan Pembelajaran
Publisher : LP. Ma'arif Janggan Magetan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62775/edukasia.v4i1.304

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Merdeka Curriculum provides flexibility in the implementation of education. Differentiate learning is one example of teacher flexibility to design learning activities that are matched to the learning needs of students. The purpose of this research is to find out the implementation of differentiated learning in the Merdeka Curriculum in history subjects at SMA Negeri 22 Surabaya. This research uses case study and interview methods as data collection techniques. The results of the study show three major points, 1) diagnostic assessments are carried out without fixed standards, 2) differentiation of content, processes and products is implemented that focuses on student’s profiles or learning styles, 3) evaluation and follow-up of implementation of differentiated learning depends on the teacher himself.
Analisis Dimensi Pengetahuan Tema II (Keberagaman Lingkungan Sekitar) pada Buku Pegangan Siswa IPS Kelas VII Kurikulum Merdeka Dewi Saraswati; Muhammad Turhan Yani; Agus Suprijono
Reslaj: Religion Education Social Laa Roiba Journal Vol. 7 No. 6 (2025): RESLAJ: Religion Education Social Laa Roiba Journal
Publisher : Intitut Agama Islam Nasional Laa Roiba Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47467/reslaj.v7i6.5604

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Kurikulum merdeka berfokus pada pengoptimalan peserta didik dalam mendalami sebuah konsep yang dibuat secara menarik dan beragam sehingga dapat menguatkan kompetensinya sehingga guru dapat dengan leluasa untuk membuat, memilih, memodifikasi bahan ajar sesuai dengan karakteristik, konteks maupun kebutuhan dari peserta didik. Sumber belajar IPS yang biasanya digunakan dalam pembelajaran IPS adalah buku pegangan guru dan siswa. Kurikulum merdeka sudah membebaskan guru untuk memilih dan membuat materinya masing-masing. Buku siswa telah diberikan oleh pemerintah sebagai acuan guru dalam mengolah materi yang ada. Namun buku pegangan tersebut hendaknya perlu dianalisis kembali sehingga materi yang ada dapat disampaikan kepada peserta didik dengan baik. Salah satu cara untuk menganalisis materi yang ada pada buku pegangan dengan menggunakan analisis dimensi pengetahuan yang merupakan teori dari Anderson dan Krathwohl (Pengetahuan Faktual, Pengetahuan Konseptual, Pengetahuan Prosedural dan Pengetahuan Metakognitif) yang diperlukan oleh peserta didik. Jenis penelitian yang digunakan dalam penelitian ini adalah kualitatif yang bersifat deskriptif. Subjek pada penelitian ini adalah buku IPS siswa Kurikulum Merdeka kelas VII Tema II Keberagaman Lingkungan Sekitar. Hasil presentase masing-masing dimensi yaitu dimensi konseptual sebanyak 38,9% , dimensi faktual sebanyak 33,3 % , dimensi prosedural sebanyak 22,2 % dan dimensi metakognitif sebanyak 5,6%. Masing-masing dimensi memiliki andil dan manfaatnya masing-masing bagi ketercapaian tujuan pembelajaran di dalam kelas.
Problematika PKN di Sekolah yang Berbasis Agama di Perkotaan Muhammad Sa’dii Fathir; Muhammad Turhan Yani; Harmanto; Agus Suprijono
EduInovasi:  Journal of Basic Educational Studies Vol. 4 No. 2 (2024): EduInovasi:  Journal of Basic Educational Studies (In Press)
Publisher : Intitut Agama Islam Nasional Laa Roiba Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47467/edu.v4i2.3192

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Citizenship training has the significance of being a vehicle for character schooling which is worked to encourage and foster shrewd and productive members of society in formal, casual and non-formal training channels which have become piece of the objectives of public instruction in Indonesia. From the consequences of the writing concentrate on that I found, it was uncovered that Civics learning or subjects assume a vital part in learning. This is because of the nature and objectives of Civics subjects which contain values that can be implemented into life so that we can become good citizens or good citizenship. The article writing method is a descriptive qualitative method using literature studies and library research. Then the results of this article are about Civics Problems in Religious Based Schools in Urban Areas. Civics Problems in Religious Based Schools in Urban Areas at this time are basically what Citizenship Education is experiencing is still the same as in previous years, namely that it still prioritizes cognitive aspects, so the aim is to create students who are critical and responsible. still not realized. In fact, most students think that Citizenship Education subjects are formal learning and are only a requirement.