Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Universa Medicina

medicina
Website

Published by Universitas Trisakti

ISSN : 19073062 EISSN : 24072230 DOI : -

Core Subject : Health, Science,

Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Universa Medicina (univ.med) is a four-monthly medical journal that publishes new research findings on a wide variety of topics of importance to biomedical science and clinical practice. Universa Medicina Online contains both the current issue and an online archive that can be accessed through browsing, advanced searching, or collections by disease or topic

Arjuna Subject : -

Articles 10 Documents

Search results for , issue "Vol 38, No 1 (2019)" : 10 Documents clear

Life style as a risk factor of human Papillomavirus co-infections with Trichomonas vaginalis in female sex workers Odigie, Efosa Bolaji; Okungbowa, Micheal Awol
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

BACKGROUNDAsymptomatic Trichomonas vaginalis (TV) and human papillomavirus (HPV) co-infection is perceived to have a devastating combined effect on victims. Hence, we investigated TV/ HPV co-infection and determined the risk factors associated with it in female sex workers (FSW).METHODSA cross-sectional study was used to recruit 338 subjects from 6 local government areas (LGAs) in Nigeria for 18 months. Agglutination tests for blood samples, and direct and wet examination of urine and vaginal swabs were conducted in the laboratory. Life style of FSWs was surveyed; data were analyzed with Chi-Square test (X2), paired and unpaired t-test and logistic regression analysis with statistical significance set at p< 0.05.RESULTSLife style characteristics were significantly associated with HPV and TV co-infection (pÂ < 0.001). The model explained 49.9% (Nagelkerke R2) of the variance in infections among FSWs and effectively classified 93.2% of cases. Those involved in oral sex were 1.795 times more likely to be infected compared to those not involved (OR: 1.795; 95% C.I.: 1.005 â€“ 33.525; p=0.001). Street and residential FSWs all have increased likelihood of being infected. Hard drug usage was also associated with an increased likelihood of being infected with the disease (OR: 3.582; 95% C.I.: 1.573 - 11.756; p=0.001).CONCLUSIONSLife style (hard drug usage and oral sex practices) was observed in association with HPV/ TV co-infection in FSWs with a preponderance of 49.9%. This study demonstrated the value of screening for genital infections in HPV positive subjects in order to reduce the probable synergistic effects of co-infections.

Progesterone decrease plasma membrane in human sperm with subnormal hypoosmotic swelling test scores Sisca, Sisca; Yunaini, Luluk; Pujianto, Dwi Ari
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

BackgroundProgesterone (P4) is known as a female hormone affecting oocyte maturation and developing uterine wall. A proteomic study identified several receptors including P4 receptors on human sperm. The role of P4 in human sperm cells remains unknown as to whether P4 has non-genomic effects on human sperm. The present study aims to determine the effect of progesterone (P4) on the hyperactivated motility and membrane integrity of human sperm cells.MethodsSemen from normal individuals was obtained from donors. The semen was washed by gradient density centrifugation. P4 was added to each semen sample to final concentrations of 0 (control), 250, 500, 750 and 1000 ng/mL. After the sample treatment was completed, the sperm membrane integrity was assessed with the hypoosmotic swelling test (sodium citrate dihydrate and D-fructose) and the hyperactivated sperm motility parameter was determined with the Computer Assisted Sperm Analyzer [CASA] (Hamilton Thorne, IVOS II, USA). The percentage was then compared between the treatment groups and the control group. The percentage differences were analyzed with the Sigmastat version 2.0 statistical program.ResultsAdministration of P4 increased sperm hyperactivated motility when compared with the control group at a concentration of 500 ng/mL, but the increase was statistically not signicant (p>0.05). In contrast, P4 decreased sperm membrane integrity significantly (p=0.042). And the mean of plasma membrane integrity in all groups was subnormal hypoosmotic swelling test score. ConclusionProgesterone administration tends to increase sperm hyperactivated motility. The integrity of plasma sperm membrane was affected by progesterone.

Cullin 1 is not associated with late-onset preeclampsia Samara, Tjam Diana; Liem, Isabella Kurnia; Prijanti, Ani Retno; Andrijono, Andrijono
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

BackgroundLate-onset preeclampsia (PE) is preeclampsia occurring after 34 weeks of gestational age or later.Â Cullin 1 (CUL1), a proangiogenic protein, is expressed in the placenta, where an imbalance between proangiogenic and antiangiogenic proteins during gestation can cause disturbance of trophoblast invasion. This defect results in vascular ischemia that may produce preeclampsia. The objective of this study was to determine the correlation between CUL1 as proangiogenic factor and late-onset preeclampsia. MethodsThis study was of analytical observational cross-sectional design and involved 44 preeclampsia patients with Â³34 weeks of gestational age (late-onset PE). The CUL1 level in the subjectsâ€™ sera, taken before they gave birth, and in homogenates of their placenta, obtained per vaginam or by cesarean section, were examined by the ELISA technique.Â Statistical analysis was performed with the Spearman correlation test with significant p value of <0.05.ResultsMedian maternal age was 31 years and median gestational age was 37 weeks.Â Median serum CUL1 was 41.78 pg/mL and median placental homogenate CUL1 was 32.24 pg per milligram of total placental tissue protein. There was no significant correlation between serum CUL1 level and late-onset preeclampsia (r=-0.281; p=0.065). There was also no significant correlation between placental CUL1 level and late-onset preeclampsia (r=-0.166; p=0.281).ConclusionSerum CUL1 and placental CUL1 were not correlated with late-onset preeclampsia. However, this study indicated that low serum CUL1 tends to prolong gestational age in preeclampsia.

Molecular characterization of methicillin-resistant staphylococci among apparently healthy students Ogefere, Helen Oroboghae; Ogunleye, Lawrence Ayodele
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

BackgroundStaphylococcus aureus are widely considered a major factor of nosocomial and community-acquired infections. This work was aimed at determining the prevalence of methicillin-resistant S. aureus (MRSA) among apparently healthy students. MethodsA cross-sectional study was conducted involving 400 nasal swab samples randomly collected from students using sterile swab sticks and processed to recover S. aureus using standard microbiological techniques. Conventional methods were used to identify the isolates and antibiotic susceptibility tests were performed using Kirby-Bauer disc diffusion method according to performance standards of Clinical and Laboratory Standard Institute guidelines. Methicillin-resistance was detected phenotypically using cefoxitin 30Âµg discs. Bacterial deoxyribonucleic acid (DNA) extraction was done on cefoxitin-resistant staphylococci isolates only using ZymoResearch (ZR) fungal/bacterial DNA MiniPrepTM kit. A polymerase chain reaction assay targeting the 16S rRNA, nuc, and mecA genes on 1.0% agarose gel electrophoresis stained with ethidium bromide was used to identify S.aureus and detect methicillin resistance. ResultsThe overall prevalence of MRSA was 5.8% using phenotypic methods. PCR amplification of the 23 phenotypically confirmed MRSA using 16S rRNA and nuc genes identified staphylococci 23/23(100%) and S. aureus 23/23(100%) at band size 886bp and 225bp respectively. However, 16(69.6%) were positive for mecA gene at band size 532bp by PCR method. Poor level of susceptibility was recorded among the MRSA namely to erythromycin (26.6%), cloxacillin (0%), augmentin (0%), cefuroxime (0%), ceftriaxone (0%) and ceftazidime (0%). Ofloxacin was the most effective antibiotic (60.9%). ConclusionActive antimicrobial surveillance of pathogenic staphylococci is important to analyze the infections and transmission rate for possible control measures.

Open reduction in neglected elbow dislocation in children: a case series Irianto, Komang Agung; Parung, Raymond; Sukmajaya, William Putera
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

BackgroundElbow deformity in children due to neglected proper fracture management is a devastating condition. The stiffness and pain complicated the function in daily activity. Successful management of neglected elbow dislocation is a challenging problem for orthopedic surgeons. In this study, we aimed to evaluate results of open reduction for neglected elbow dislocation in children.Case DescriptionThis is a case series of 13-14 years old neglected elbow dislocations, for up to 15 months. Open reduction after external distractor and followed by intensive rehabilitation was implemented. Clinical and functional outcome were evaluated within 4-7 years. Initial average elbow flexion was 53,3Â°, extension was 0Â°, arc of flexion was 53,3Â°, arc of pronation-supination was 150Â° and Mayo Elbow Performance Index (MEPI) was 80. Clinical and functional outcome were evaluated within 4-7 years. At follow-up after open reduction, the improvement in whole range of movement was significant. Average elbow flexion was 118,3Â°, extension was 36,67Â°, arc of flexion was 81,67Â°, arc of pronation-supination was 133Â°. The average improvement of flexion was 65Â°, arc of flexion was 31,67Â°, and arc of pronation-supination was 8,3Â°. The average loss of flexion was 15,5%, arc of flexion was 44,2%, and arc of pronation-supination was 10,7% compared with uninjured side. The average Mayo Elbow Performance Index (MEPI) was 96,67; all with excellent results.ConclusionPlanned and well execution open reduction in pediatric neglected elbow dislocation may bring back the painless movement within normal daily function.

Psychometric properties of Persian version of Beck depression inventory in coronary patients Ahmadi, Seyed Mojtaba; Masjediarani, Abbas; Bakhtiari, Maryam; Davazdahemamy, Mohamad Hasan; Mohamadian, Rasul
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

BackgroundObtaining psychometric properties regarding specific populations increases diagnostic accuracy and reduces economic health burdens. Beck depression inventory-second version (BDI-II) is useful for the screening and assessment of depression in clinical and research settings. The aim of the present study was to investigate the psychometric properties of the Persian (Farsi) version of BDI-II in patients with coronary heart disease (CHD). MethodsA cross-sectional study was conducted on 284 patients with CHD admitted to Imam Ali Hospital in Kermanshah. They were first given a structured clinical interview (SCID-I) and then were asked to complete the Beck depression inventory-II (BDI-II), patient health questionnaire 9 (PHQ-9) and generalized anxiety disorder 7 (GAD-7). Data were analyzed by descriptive statistics, Cronbach’s á, Spearman’s correlation coefficient, exploratory factor analysis and receiver operating characteristic curve (ROC).ResultsThe internal consistency measured using Cronbach’s alpha was 0.90. The obtained correlation of BDI-II with PHQ-9 and GAD-7 was 0.74 and 0.65, respectively (p< 0.001). Factor analysis of the inventory revealed 5 factors, namely cognitive, somatic , impaired performance , negative attitude to self and ,and self punishment respectively. The cut-off point for CHD patients was 11 with sensitivity of 0.78 and specificity of 0.81 according to the Youden index and 10 with sensitivity of 0.80 and specificity of 0.77 according to the two-stage approach. The area under the curve was 0.86 (95% Confidence Interval 0.82-0.90). ConclusionThe Persian version of the BDI-II possesses the acceptable psychometric properties that can be used to screen depression in CHD patients.

Acupressure has not an analgesic effect in patients with renal colic: a randomized controlled trial Bolvardi, Ehsan; Zarmehri, Bahram; Mousavi Bazzaz, Seyed Mojtaba; Khorsand Vakilzadeh, Ali; Foroughian, Mahdi; Hoseini Faegh, Hasan; Mehramiz, Neema John
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

BackgroundEasing renal colic (RC) pain is of the most important issues in the emergency departments. This study was conducted to investigate the analgesic effects of intravenous paracetamol in comparison to acupressure and intramuscular diclofenac in patients with RC.MethodsThis randomized clinical trial was conducted on 96 eligible patients with RC, visiting the Emergency Department of Imam Reza Hospital of Mashhad, Iran. The participants were selected by consecutive non-random sampling method, and were randomized in three groups, each comprising of 32 participants. The first and second groups received 75 mg intramuscular diclofenac and 1g intravenous paracetamol, respectively. In the third group, three acupressure points were manually stimulated for six minutes. The pain score was measured by Visual Analog Scale for pain at baseline and after 10, 30, and 60 minutes. Collected information analyses by SPSS version 20 and interpreted using descriptive statistics (frequency, percentage) and inferential statistics (chi-square test).ResultsThe mean age was 31.60 ± 7.42 years (range:18-50). The two methods (diclofenac and paracetamol groups) were significantly better in pain reduction compared to acupressure after 10 minutes (p<0.001). Ninety four percent of participants in diclofenac group, 87% of paracetamol group and none of acupressure group were completely satisfied with their treatment method (p<0.001).ConclusionThis study demonstrated that acupressure did not effectively reduces renal colic pain. It seems that contrary to acupressure, intravenous paracetamol is a safe and effective analgesic medicine for patients with RC.

CD10 expression in gastric carcinoma is correlated with tumor grade and survival Jafarian, Amir Hosein; Kooshki Forooshani, Melika; Takallou, Leila; Mohamadian Roshan, Nema
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

BackgroundGastric carcinoma (GC) is the most common non-skin malignancy in Iranian men and the second leading cause of cancer-related mortality. Invasion and metastasis are considered as the major causes of cancer-related morbidity and mortality. Proteinases such as matrix metalloproteinases play an important role in tumor progression and mediating extracellular matrix remodeling. CD10 is a 90-110kd cell surface zinc-dependent metalloproteinase and there is evidence that this membrane protein may facilitate invasion and/or metastasis of tumoral cells. The objective of this study was to determine the frequency of CD10 expression in the stromal cells of GC and determine its relationship with survival and clinicopathological factors. MethodsA cross-sectional study was performed involving 50 patients with histopathologic diagnosis of GC. CD10 expression was determined by immunohistochemistry (IHC). Survival of the patients as well as the grade and stage of the tumors and demographic variables were documented. The Kaplan-Meier test was used for data analysis.ResultsStromal CD10 was detected in 46% of the GC stromal cells. No immunoreactivity was identified in the stromal cells of normal adjacent tissue. Stromal CD10 expression in gastric carcinoma did not correlate with the age and gender of the cases as well as the size and location of the tumor, and lymph node involvement but correlated with tumor stage (p=0.01), tumor grade(p=0.01) and patients’ survival (p=0.02). ConclusionStromal CD10 expression is correlated with tumor differentiation, clinical stage and survival in GC. CD10 expression could be considered as a negative prognostic factor for gastric carcinoma.

The role of occupational health services in the universal health coverage era in Indonesia Mansyur, Muchtaruddin
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

In accordance to Act No 24 Year 2011 on The Social Security Administrating Body, the Indonesian National Social Security program is managed byÂ two national organizations, namely: Social Security Administering Body for Health (Badan Penyelenggara Jaminan Sosial Kesehatan = BPJS Kesehatan) and Social Security Administering Body for Labor (Badan Penyelenggara Jaminan Sosial Ketenagakerjaan = BPJS Ketenagakerjaan). The former is responsible for providing health coverage for all Indonesians through the National Social Health Insurance Scheme known as the Jaminan Kesehatan Nasional/JKN. The latter is Â responsible for Â providing the worker's social security consisting of Provident Fund Benefit, Accident Benefit, Pension Benefit, and Death Benefit.1The Indonesian government has been continuously improving the health service program towards better national universal health coverage and has set the 2019 functional achievement target of 95% of the population enrolled in the program. To ensure that this target of Â the program will be achieved, Â the government pays the premium of BPJS Kesehatan of the poor and near poor.2

Mild anxiety and depression related to elevated dopamine level Fidianingsih, Ika; Nurmasitoh, Titis; Arjana, Adika Zhulhi; Devita, Ninda; Khoiriyah, Umatul
Universa Medicina Vol 38, No 1 (2019)
Publisher : Faculty of Medicine, Trisakti University

BackgroundDopamine is an important neurotransmitter that plays a role in the pathogenesis of anxiety and depression. Dopamine secretion occurs when there is a pleasurable stimulus. Blood dopamine levels have the potential to be developed as biomarkers of depression or anxiety, but previous studies related to the relationship between dopamine levels and levels of anxiety and depression are still controversial. The purpose of this study was to determine the correlation between anxiety and depression score with dopamine level in young adults. MethodsThis was an observational cross sectional study. A total of 43 subjects aged 18 to 40 years were recruited by consecutive non-random sampling according to inclusion and exclusion criteria. Anxiety and depression were assessed using the Beck anxiety inventory and Beck depression inventory-II questionnaire. Dopamine plasma level was measured using the enzyme-linked immunosorbent assay (ELISA). The Spearman rho correlation test was used to analyze the data and p<0.05 was considered significant.Results The median dopamine levels in respondents with mild, moderate and severe anxiety were respectively: 77.79; 63.43; 62.51 ng/mL (p=0.043). The median dopamine levels in respondents with reasonable depression, mood disorder, moderate and severe depression were respectively: 79.2; 61,32; 62,51; 60.24 (p=0.001). Correlation test results showed a weak correlation between dopamine and anxiety (r=- 0.310) and a moderate correlation for depression (r=-0.505).ConclusionMild anxiety and depression were associated with elevated dopamine level in young adults. Further studies are required to confirm the role of dopamine metabolism in anxiety and depression in young adults.

Page 1 of 1 | Total Record : 10

Filter by Year

2019 2019

Filter By Issues

All Issue Vol. 44 No. 3 (2025): Ahead Of Print Vol. 44 No. 2 (2025) Vol. 44 No. 1 (2025) Vol. 43 No. 3 (2024) Vol. 43 No. 2 (2024) Vol. 43 No. 1 (2024) Vol. 42 No. 3 (2023) Vol. 42 No. 2 (2023) Vol. 42 No. 1 (2023) Vol. 41 No. 3 (2022) Vol. 41 No. 2 (2022) Vol. 41 No. 1 (2022) Vol. 40 No. 3 (2021) Vol. 40 No. 2 (2021) Vol. 40 No. 1 (2021) Vol. 39 No. 3 (2020) Vol 39, No 3 (2020) Vol. 39 No. 2 (2020) Vol 39, No 2 (2020) Vol. 39 No. 1 (2020) Vol 39, No 1 (2020) Vol 38, No 3 (2019) Vol 38, No 2 (2019) Vol 38, No 2 (2019) Vol 38, No 1 (2019) Vol 38, No 1 (2019) Vol 37, No 3 (2018) Vol 37, No 3 (2018) Vol 37, No 2 (2018) Vol 37, No 2 (2018) Vol. 37 No. 2 (2018) Vol 37, No 1 (2018) Vol 37, No 1 (2018) Vol 36, No 3 (2017) Vol 36, No 3 (2017) Vol. 36 No. 3 (2017) Vol 36, No 2 (2017) Vol 36, No 2 (2017) Vol 36, No 1 (2017) Vol 36, No 1 (2017) Vol 35, No 3 (2016) Vol 35, No 3 (2016) Vol 35, No 2 (2016) Vol 35, No 2 (2016) Vol 35, No 1 (2016) Vol 35, No 1 (2016) Vol. 35 No. 1 (2016) Vol 34, No 3 (2015) Vol 34, No 3 (2015) Vol. 34 No. 2 (2015) Vol. 34 No. 1 (2015) Vol. 33 No. 3 (2014) Vol. 33 No. 2 (2014) Vol. 33 No. 1 (2014) Vol. 32 No. 3 (2013) Vol. 32 No. 2 (2013) Vol. 32 No. 1 (2013) Vol. 31 No. 3 (2012) Vol. 31 No. 2 (2012) Vol. 31 No. 1 (2012) Vol 31, No 1 (2012) Vol 31, No 1 (2012) Vol 30, No 3 (2011) Vol 30, No 3 (2011) Vol 30, No 2 (2011) Vol 30, No 2 (2011) Vol 30, No 1 (2011) Vol 30, No 1 (2011) Vol 29, No 3 (2010) Vol 29, No 3 (2010) Vol 29, No 2 (2010) Vol 29, No 2 (2010) Vol 29, No 1 (2010) Vol 29, No 1 (2010) Vol 28, No 3 (2009) Vol 28, No 3 (2009) Vol 28, No 2 (2009) Vol 28, No 2 (2009) Vol 28, No 1 (2009) Vol 28, No 1 (2009) Vol 27, No 4 (2008) Vol 27, No 4 (2008) Vol 27, No 3 (2008) Vol 27, No 3 (2008) Vol 27, No 2 (2008) Vol 27, No 2 (2008) Vol 27, No 1 (2008) Vol 27, No 1 (2008) Vol 26, No 4 (2007) Vol 26, No 4 (2007) Vol 26, No 3 (2007) Vol 26, No 3 (2007) Vol 26, No 2 (2007) Vol 26, No 2 (2007) Vol 26, No 1 (2007) Vol 26, No 1 (2007) More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota adm. jakarta barat,

Dki jakarta

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

Contact Email -

Phone -

Journal Mail Official -

Editorial Address -

Location Kota adm. jakarta barat, Dki jakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota adm. jakarta barat,

Dki jakarta

INDONESIA