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Paediatrica Indonesiana
Published by Ikatan Dokter Anak Indonesia
ISSN : 00309311     EISSN : 2338476X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.
Arjuna Subject : -
Articles 2,118 Documents
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The efficacy of suppository versus oral ibuprofen for reducing fever in children Suhesti Handayani; Sri Rezeki Hadinegoro; Sudigdo Sastroasmoro
Paediatrica Indonesiana Vol 45 No 5 (2005): September 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi45.5.2005.211-6

Abstract

Background Ibuprofen suppository is used to reduce fever inchildren who are unable to receive it orally. The effectiveness ofibuprofen suppository compared to that of oral ibuprofen has notbeen documented in Indonesian children.Objective The aim of this study was to compare the efficacy ofibuprofen suppository with that of oral ibuprofen for reducingfever in children.Methods This study was a randomized clinical trial without blind-ing on children aged 2-5 years with body weight of 12.5 to 16 kgwho had fever. Subjects received ibuprofen in either oral (7.5mg/kg) or suppository (125 mg) form. The temperature was mea-sured prior to ibuprofen administration, 30 minutes afterwards,and every subsequent half hour until the end of the sixth hour.Any observed adverse effects were recorded.Results Mean time needed for fever reduction was 2.72 (SD 1.1)hours in the suppository group, compared to 3.43 (SD 0.9) hoursin the oral group (P=0.004). The mean rate of fever reduction inthe suppository group was 0.90 (SD 0.4) °C/hour, while in theoral group it was 0.61 (SD 0.3) °C/hour. However, mean maxi-mum temperature lowering ability did not differ significantly [2.11(SD 0.7) °C for the suppository group and 1.99 (SD 0.7) °C, forthe oral group (P=0.489)]. There was no significant difference inmean duration of effect [220.8 (SD 83.0) hours for the supposi-tory group and 196.6 (SD 92.7) hours for the oral group (p=0.231)].Conclusions There was no significant difference between bothpreparations in maximum temperature lowering ability and dura-tion of effect. Temperature reduction was significantly fasterwith the administration of ibuprofen suppository
Adiponectin and highly sensitive C-reactive protein levels in obese children aged 9 to 15 years Frecilia Regina; Kristellina Tirtamulia; Sarah Maria Warouw
Paediatrica Indonesiana Vol 51 No 1 (2011): January 2011
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi51.1.2011.7-11

Abstract

Background Childhood obesity is a widespread and growing problem associated with health problems such as metabolic syndrome, diabetes mellitus and cardiovascular disease. A low􀁗grade chronic inflammatory state, reflected by decreased adiponectin and increased highly sensitive C􀁗reactive  protein (hsCRP) levels, may play a role in metabolic syndrome associated with obesity.Objective To assess and compare adiponectin and hsCRP levels in obese and nonnal weight children.Methods We conducted a cross-sectional, case􀁗controlled study in Manado from May to July 2010. Subjects were selected from obese, but otherwise healthy children aged 9-15 years. Control subjects were schoolmates 'With normal body mass index (BMI). We perfonned physical examinations, measured blood pressure, weight and height, and calculated BMI for all subjects. After an overnight fast, all subjects were tested for fasting blood glucose, adiponectin and hsCRP levels.Results The mean adiponectin level in the obese group was 3.6 μg/mL (SD 1.43), lower than that of the normoweight group, 4.8 μg/mL (SD 1.67) (P<0.0001). The mean hsCRP level in the obese group was 3.3 mg/L (SD 3.62) while that of the normoweight group was 0.8 mg/L (SD 1.39) (P<0.0001). There was no inverse correlation between adiponectin and hsCRP levels in obese group (r= 0.048; P= 0.362).Conclusions Lower adiponectin and higher hsCRP levels in the obese group is consistent 'With a low-grade chronic inflammatory state. Other factors that influence adiponecrin and hsCRP production or inflammatory pathways of other adipokines need further evaluation. Early intervention is needed to reduce body weight in obese children.
Association between sleep quality and obesity in adolescents Nova Juliana Sagala; Sri Sofyani; Supriatmo Supriatmo
Paediatrica Indonesiana Vol 57 No 1 (2017): January 2017
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (491.31 KB) | DOI: 10.14238/pi57.1.2017.41-6

Abstract

Background Sleep quality can be measured by the Pittsburgh Sleep Quality Index (PSQI). One component of the PSQI is duration of sleep, which is often highly inadequate in adolescents. Inadequate sleep may lead to obesity in adolescents.Objective To assess for an association between sleep quality and incidence of obesity in adolescents.Methods This case–control study was conducted at Santo Thomas I Senior High School, Medan, North Sumatera,  from July to August 2015. A total of 227 adolescents were divided into two groups: the case group consisting of 101 obese adolescents and the control group consisting of 126 non-obese adolescents. Study data was collected by questionnaires and PSQI. We interviewed subjects on their food consumption for the three days prior and calculated their average caloric intake. The data were analyzed by non-paired T-test, Chi-square, Mann-Whitney, and multivariate analyses.Results There was a significant association between sleep quality and obesity [OR 3.87 (95%CI 1.920 to 7.829)]. Median PSQI (range) score in the obese group was significantly higher than in the non-obese group [6.00 (2-16) vs. 5.00 (2-12), respectively (P=0.0001)]. In addition, sleep latency (P=0.002) and sleep duration (P=0.0001) were significantly different between groups. Multivariate analysis revealed a significant association between poor sleep quality and high caloric intake.Conclusion Sleep duration in obese adolescents is significantly shorter than that in non-obese adolescents. In addition, sleep latency in obese adolescents was significantly longer than that in non-obese adolescents.
Steatorrhoea in Acute Enteritis A. H. Sutanto; Rahayu Sa'at; H. Siregar
Paediatrica Indonesiana Vol 22 No 11-12 (1982): November - December 1982
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi22.11-12.1982.217-21

Abstract

Out of a total of 678 patiems, 190 infants presenting acute en1eritis. 95.7%were below 2 yea·s of age and 86.8% were below 1 year of age. Fat dropletswere found in 25 out of 143 patients (17,4%) below 12 months of age.Sugar intolerance was found in 39 of 86 infollts examined (45,3%). Thehighest prevalence was in the a,;P group of 6- 9 11101:ths.The prevalence of concomitant intestinal parasites was low.
Comparison of peak expiratory flow rate (PEFR) before and after physical exercise in obese and non-obese children Febrina Z. Siregar; Gabriel Panggabean; Ridwan M. Daulay; Helmi M. Lubis
Paediatrica Indonesiana Vol 49 No 1 (2009): January 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (104.458 KB) | DOI: 10.14238/pi49.1.2009.20-4

Abstract

Background  Obesity  has  been  associated  with  respiratorycomplications  and  it  is  believed to reduce lung volume. Obesityimposes additional stress on  ventilation  during exercise  andmay even result in pulmonary function impairment. Exerciseinduced-bronchospasm has also been found in obese children.Lung function tests  can  be useful to confirm diagnosis, responseto therapy, or prediction of lung and respiratory diseases.  Thepeak  flow  meter  is  an  inexpensive, practical  way  to measure lungfunction, and  can  detect the early warning signs  of  a decrease inlung function.Objective  To  compare the peak expiratory  flow  rate (PEFR) beforeand after physical exercise in obese and non-obese primary schoolboys aged 6 to  12  years old.Methods  A quasi-experimental study using the one group pretest-posttest design was performed  on  30  obese children  (BMI  abovethe  95<h  percentile)  and  30 non-obese children  (BMI  betweenthe  5<h  - 85'h percentile) using a mini-Wright peak  flow  meterto evaluate the PEFR before  and  after eight minutes  of  physicalexercise. Height, weight, body mass index,  and  physical statuswere determined before testing.Results  The  PEFR before  and  after exercise were 14.80 for obesechildren and 9.76 for non-obese children.  The  mean value forPEFR between obese and non-obese children was significantlydifferent  (P<0.05).Conclusion  The  PEFR for obese children  is  significantly lowerthan  non  obese children  even  before physical exercise.
An overview of an amplitude integrated EEG Setyo Handryastuti
Paediatrica Indonesiana Vol 47 No 2 (2007): March 2007
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1583.083 KB) | DOI: 10.14238/pi47.2.2007.47-54

Abstract

Amplitude integrated EEG (aEEG) has been used widely in developed countries for years. It was initially developed by Maynard and Prior 1 in the early 1970s and later adapted for neonatal use by Hellstrom-Westas and Svenningsen 2 . It is especially used for monitoring term newborns after having survived from birth asphyxia.During the last decade neonatal health care in Indonesia has developed. Monitoring of physiological parameters such as ECG, heart rate, blood pressure, oxygen saturation and temperature have been integrated inour neonatal intensive care unit but equipments like continuous EEG monitoring and aEEG to evaluate brain function have not been well-known among our neonatologists and pediatricians. The consequence is the de-crease of infant mortality was not associated with the improvement of quality of life of the survivors due to neurodevelopmental problems caused by various diseases during neonatal period. In the future, it can be prevented by using brain function monitoring in high risk newbornfor neurodevelopmental problem in conditions such as hypoxic-ischemic encephalopathy (HIE), prematurity, neonatal seizures, central nervous system infection, metabolic disorders, intraventricular or intracranial bleeding and brain malformation. This article gives an overview about aEEG and its role in newborn. 
Association between hepatitis C infection and number of screened blood unit transfusions in thalassemic children Diah Asri Wulandari; Iesje Martiza; Yasmar Alfa; Dwi Prasetyo
Paediatrica Indonesiana Vol 45 No 4 (2005): July 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi45.4.2005.182-6

Abstract

Background Donor blood screening test for antibody againsthepatitis C virus (HCV) by third generation ELISA is widely used.However, there is still a window period during which a donor mayalready be infected despite a negative screening test.Objectives To determine the prevalence of hepatitis C infection inthalassemic children who had received screened donor blood andto seek the association between HCV infection and the number ofblood unit transfusions received.Methods This was an analytic cross-sectional study. Sixty-sevenchildren who had received third generation ELISA screened donorblood were examined for HCV antibody. The study was conductedin Hasan Sadikin General Hospital, Bandung, from January toMarch 2004. The prevalence of hepatitis C was presented in per-centage. The association between HCV infection and sex, age,interval between transfusions, and the number of blood unit trans-fusions received was determined by univariate analysis and logis-tic regression analysis.Results In univariate analysis, significant difference between HCV-infected and uninfected subjects was found in the mean age andmean number of blood units transfused (P<0.001). In logistic re-gression analysis, we found a significant association between thequantity of transfused blood with positive HCV antibody (P<0.001).The odds ratio for positive HCV antibody was 1.08 for each bloodunit transfusion received (95%CI 1.02;1.14). The prevalence ofhepatitis C in thalassemic children who received third generationELISA screened blood was 22.4% (95%CI 12.4%;32.4%). Thisprevalence is lower than that in a previous study of thalassemicchildren receiving unscreened blood (50.8%).Conclusions The prevalence of HCV infection in thalassemic chil-dren who had received screened donor blood is 22.4%. HCV in-fection is significantly associated with the number of screened bloodunit transfusions
Ferrous sulfate liquid for the treatment of iron deficiency anemia Soemantri Soemantri; A. G. Soedigbia; I. Hardiman; Taty Hendarto; Widjaja Widjaja
Paediatrica Indonesiana Vol 21 No 1-2 (1981): January - February 1981
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi21.1-2.1981.21-34

Abstract

A study on the effect of ferrous sulfate liquid (lberet - 500 liquid) was conducted on a group of well-nourished children aged 6 months - 5 years.After 3 months 0/ treatment, hematological measurements revealed a statistically significant improvement as compared to the control group receiving placebo. Side effects were also found to be minimal. Thus ferrous sulfate liquid is recommended for treatment or supplement to anemia eradication, preferably associated with a high dose of vitamin C.
A Case of Paratyphoid Fever Accidentally Treated with Amoxycillin I. Darmansjah
Paediatrica Indonesiana Vol 14 No 7-8 (1974): July - August 1974
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (337.412 KB) | DOI: 10.14238/pi14.7-8.1974.132-4

Abstract

A case of paratyphoid-fever isreported below which respondeddramatically to 6 (D (-) -Amino-p-Hydroxyphenyl acetamido) - Penicil-lanic acid or amoxycillin, known inIndonesia under the trade name ofAmoxil (250 mg crupsules).
Behavior of elementary schoolchildren with iron deficiency anemia after iron therapy Rina A.C. Saragih; T. Mirda Zulaicha; Sri Sofyani; Bidasari Lubis; Iskandar Z. Lubis
Paediatrica Indonesiana Vol 49 No 5 (2009): September 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (107.039 KB) | DOI: 10.14238/pi49.5.2009.276-80

Abstract

Background Some studies had been performed to determine theassociation between iron status and children's behavior yet it isstill controversial.Objective To investigate whether iron therapy has an effect onthe behavior of children with iron deficiency anemia (IDA).Method A randomized placebo-controlled clinical trial wasconducted in Labuhan Batu on November 2006-April2007. IDAwas defined as Hb < 12 g/dl, MCHC< 31%, ROW index > 220and Mentzer index> 13. Elementary school children (6-12 yearsold) with IDA were randomly assigned to the treatment groupwith a daily therapy of 6 mg iron/kg/day or placebo group for three months. The subjects' behavior was evaluated with child behavior check list (CBCL) before and six months after intervention.Results After six months, 110 subjects completed the therapy.Scores of CBCL in iron group after intervention were internalizing42.64 (SO 9.95), externalizing 37.13 (SO 9.04) & total score 38.24 (SO 10.20). There was significant decreased on externalizing and total problems score in the treatment group after intervention (P< 0.05). However, there was no significant difference on scores between groups.Conclusion Iron therapy had significantly decrease CBCL scoreon externalizing and total problems in the treatment group,however there was no significant difference on scores if comparedwith placebo group.

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