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INDONESIA
Paediatrica Indonesiana
Published by Ikatan Dokter Anak Indonesia
ISSN : 00309311     EISSN : 2338476X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.
Arjuna Subject : -
Articles 2,118 Documents
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Randomized controlled trial of Phyllanthus niruri Linn extract Patria Vittarina Sarisetyaningtyas; Sri Rezeki Hadinegoro; Zakiudin Munasir
Paediatrica Indonesiana Vol 46 No 2 (2006): March 2006
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi46.2.2006.77-81

Abstract

Background Clinical benefits of antiviral treatment in childrenexperience varicella without complications, remains controversial.Phyllanthus niruri Linn extract as a natural medicine is used toincrease cellular and humoral immunity.Objective To determine the efficacy and safety of Phyllanthusniruri Linn extract in the treatment of varicella in children comparedto placebo.Methods This was a double-blind randomized controlled trial onchildren ages 2-14 years who experienced varicella without com-plications. Subjects were randomly assigned to receive eitherPhyllanthus niruri Linn extract syrup (5 mg/5ml, 3 times daily) orplacebo. Efficacy was measured by calculating the number of pap-ules and crusts after taking the extract for 4 days of administration.A five-day monitoring sheet to record daily follow up and adverseeffects of the subjects were given to their parents.Results Efficacy of Phyllanthus niruri Linn measurement basedon no more new papules occurred at the five-day monitor was de-tected in 46 subject (51.1%) of the Phyllantus niruri Linn groupcompared to the placebo group (P=0.723). Meanwhile, the differ-ence of efficacy based on time of crusts disappear in Phyllanthusniruri Linn and placebo group were 22 subjects (43.1%) and 15subject (30.0%), respectively (P=0.053). This finding proved haveclinical benefit (NNT=7.6).Conclusion There was no significant difference between the ef-ficacy of Phyllanthus niruri Linn and placebo in terms of the pre-vention appearing new papules and crusts. However, clinicallyPhyllanthus niruri Linn accelerates appearing and aborting crustcompared to placebo
Upper arm circumference measurement for detecting overweight and obesity in children aged 6-7 years Dewi Rosariah Ayu; Aditiawati Aditiawati; Julius Anzar; Erial Bahar
Paediatrica Indonesiana Vol 57 No 1 (2017): January 2017
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (288.37 KB) | DOI: 10.14238/pi57.1.2017.23-9

Abstract

Background Obesity is a worldwide problem and is associated with increased risk of metabolic syndrome. Nutritional status in children has traditionally been determined by body mass index (BMI) scores, but with limitations. Upper arm circumference measurement may be a better predictor of energy, protein, and fat storage, as well as a simpler method for screening overweight and obesity in children.Objective To determine the diagnostic value of upper arm circumference compared to BMI for detecting overweight and obesity in children aged 6-7 years.Methods This diagnostic study with a cross-sectional design was performed from September to October 2015 at 16 primary schools in Palembang, Indonesia. We measured the heights, weights, and upper arm circumferences, and calculated BMIs of 2,258 children. Receiver-operator characteristic (ROC) curve analysis was used to find an optimal upper arm circumference cut-off point to detect overweight and obesity. Diagnostic value was calculated by using a 2x2 table analysis.Results The prevalences of overweight and obesity were 5.8% and 11.7%, respectively. The optimal upper arm circumference cut-off points for detecting overweight in children aged 6-7 years was 185 mm (sensitivity 88.1% and specificity 78.3%), and for obesity was 195 mm (sensitivity 90.15% and specificity 86.65%). Upper arm circumference had a strong correlation with BMI.Conclusion Upper arm circumference measurement is an accurate method fordistinguishing between normoweight, overweight, and obesity in children aged 6-7 years.
Clinical Features and Management of Some Muscular Disorders in Children - A Brief Review Dwi Putro Widodo
Paediatrica Indonesiana Vol 38 No 11-12 (1998): November - December 1998
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3326.267 KB) | DOI: 10.14238/pi38.11-12.1998.233-42

Abstract

Study has proven that electrical activity of resting and contracting skeletal muscles and conduction of the nerve impulse have become one of the most useful diagnostic tools in neurology. EMG and nerve conduction studies have become indispensable in the diagnosis and management of peripheral nerve and muscle disease (neurological differential diagnosis).
Relation of complementary foods and anemia in urban underprivileged children in Surakarta Endang Dewi Lestari; Annang Giri Moelya; Elief Rohana; Budiyanti Wiboworini
Paediatrica Indonesiana Vol 47 No 5 (2007): September 2007
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (230.429 KB) | DOI: 10.14238/pi47.5.2007.196-201

Abstract

Background Iron deficiency anemia (IDA) is still prevalent inIndonesian children. Attempt to treat patients with IDA withiron supplementation has been difficult because of lowcompliance.Objective To determine the complementary foods that contributesin the prevalence of anemia in children.Methods A cross sectional study was conducted in three urbanunderprivileged villages. Healthy children aged 6-23 months atthe time of interview were selected. The questionnaire wasspecially developed for determining the risks of IDA. We tookblood sampling to measure the hemoglobin concentration.Results A total of 86 children participated in the study; but only dataof 78 children were available for analysis. The prevalence of anemiaamong those children was 35%. Most children (90%) consumedanimal protein inadequately. Rice-based diet was the main meal ofmost children (97%). Analysis of possible factors associated with theanemia showed that inadequate plant or animal protein consumption,wasted children, less than 2 orange consumption, not consumingiron fortified formula/cereal had OR 1.2 (95%CI 0.40; 3.61), 4.13(95%CI 0.48;35.45), 4.67 (95%CI 1.04;20.04), 6.25 (95% CI1.32;29.55) and 3.15 (95%CI 1.18;8.41), respectively. Logistic analysisrevealed that the factors associated with anemia were wasted children(OR 9.10, 95%CI 1.38;60.18), low or no orange consumption (OR7.86, 95%CI 1.36;45.40) and not consuming iron fortified formula/cereal (OR 3.01, 95%CI 1.02;8.90).Conclusion In children with rice-based diet as main meal,consuming orange as an enhancing factor should also be addressedin order to prevent anemia.
Effect of length of albendazole treatment against Trichuris trichiura infection Aridamuriany D Lubis; Syahril Pasaribu; Muhammad Ali; Munar Lubis
Paediatrica Indonesiana Vol 53 No 5 (2013): September 2013
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (281.434 KB) | DOI: 10.14238/pi53.5.2013.245-9

Abstract

Background Trichuris trichiura is one of the most common soil-transmitted helminth that infects school-aged children. A single dose of albendazole has been shown to have wide variations in cure and egg reduction rates. Some studies have suggested that repeated doses of albendazole might increase its effectiveness.Objective To compare the anti-trichuriasis effect of 400 mg albendazole taken daily for five consecutive days vs. seven consecutive days.Methods A randomized open clinical trial was conducted from August to September 2009 on elementary school children at Jaring Halus in the North Sumatera Province. Stool specimens were collected before treatment and on days 7, 14, 21, and 28 after initiation of treatment, and examined by the Kato Katz method. Subjects were randomized into two groups. Group I received 400 mg albendazole daily for five consecutive days and Group II received 400 mg albendazole daily for seven consecutive days. Cure rates and egg reduction rates were compared using Chi-square and T-tests, respectively.Results One hundred twenty-one children were enrolled, consisted of 61 children in Group I and 60 in Group II. For the first week after treatment ended, the cure rates in Group II was higher (86.7%) than in the Group I (39.3%) (P=0.001), as well as in the second week after treatment ended (88.3% vs 68.9%, P=0.017). However, after 3rd and 4th weeks, the cure rates were no longer significantly different. Egg reduction rate was also statistically higher in the Group II [20.3 (SD 23.77) %] compared to Group I [6.6 (SD 11.30) %].Conclusions Albendazole for seven consecutive days is more effective in curing Trichuris trichiura infection in the 1st and 2nd weeks after treatment compared to that of five consecutive days, as well as in egg reduction rate, but the length of treatment does not influence the cure rate after the 3rd and 4th weeks.
The benefit of using plastic-covered mattresses and pillows on the frequency of asthma attacks in children with house dust mite allergy Luh Putu Winansari Ratih; Hendra Santosa
Paediatrica Indonesiana Vol 45 No 2 (2005): March 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (343.579 KB) | DOI: 10.14238/pi45.2.2005.60-4

Abstract

Background House dust mite (HDM) is abundant in tropical ar-eas with an environmental temperature of 25-30 0 C and humidityof more than 50%. Minimizing exposure to HDM allergens will de-crease the frequency of asthma attacks in children with HDM hy-perreactivity.Objective To investigate the benefit of using plastic covered mat-tresses and pillows in decreasing the frequency of asthma attacksin children allergic to HDM.Methods This is a longitudinal analytical study on children aged3–12 years who showed positive HDM skin prick test (SPT). Thesubjects received communication, information, and education (CIE)for the first 3 months and CIE and plastic-covered mattresses andpillows for the second 3 months. The frequency of asthma attackswas observed for the two periods.Results Twenty-six children with asthma were included in this study,16 were boys and 10 were girls. SPT results were +2 in 17 chil-dren, +3 in 8 children, and +4 in 1 child, respectively. During theCIE as well as the CIE + plastic intervention periods, asthma at-tack frequency was decreased significantly in the 1 st , 2 nd , and 3 rdmonths. Among several variables (age, sex, SPT, atopic history infirst-degree relative, and other atopic history), age was the onlyone significantly related to asthma attack frequency.Conclusion Covering mattresses and pillows with plastic de-creased the frequency of asthma attacks in children with positiveSPT to HDM
Comparison of metabolic syndrome criteria in obese and overweight children Astrid Anastasia Malonda; Helena Anneke Tangkilisan
Paediatrica Indonesiana Vol 50 No 5 (2010): September 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi50.5.2010.295-9

Abstract

Background Metabolic syndrome (MS) is a group of disorders which occur in relation to increasing body weight. Only a few studies have reported the differences in the fulfillment of MS criteria between obese and overweight children, and none were from Indonesia.Objective To detennine the differences in metabolic syndrome disorders between obese and overweight children.Methods A cross-sectional study was conducted in Manado from May to August 2010. The diagnosis of MS is established by fulfilling three of five criteria: waist circumference  ≥90th percentile, blood pressure ≥ 90th  percentile, fasting blood sugar (FBS) ≥ 100 mg/dL, triglycerides  ≥110 mg/dL and high density lipoprotein (HDL) ≤40 mg/dL. Obesity was defined as body mass index (BMI) of> 3 SD and overweight as BMI of 2-3 SD. Results Results ere analyzed by x2 and t-test. Results Thirty obese and 30 overweight children aged 10-14years were examined for the disorders of MS. Twenty􀁄three obese and 4 overweight children had waist circumferences  ≥90th percentile. Seventeen obese and 3 overweight children had blood pressure  ≥90th percentile. No significant differences in FBS, HDL, and triglycerides were observed between the two groups. Thirteen obese children met the MS inclusion criteria, while only 1 overweight child did so (P<0.001).Conclusions High blood pressure (≥90th percentile) and waist circumference (≥90th  percentile) occurred were observed at higher frequency in obese children than in overweight children. The occurrence of MS in obese children was significantly higher than in overweight children.
C3 and C4 Complements in Glomerular Disorders in Children H. Alatas; I.G.N. Wila Wirya; T. Tambunan
Paediatrica Indonesiana Vol 18 No 3-4 (1978): March - April 1978
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (505.809 KB) | DOI: 10.14238/pi18.3-4.1978.75-82

Abstract

Seventy children who were hospitalized for kidney diseases in the Nephrological ward Department of Child Health, University of Indonesia, Jakarta were used in this study. Thirty seven patients sufferfng from acute poststreptococcal Glomerulonephritis (A.G.N.), 3 patients with Membranoproliferative Glomerulonephritis (M.P.G.N.) and 30 patients with Nephrotic Syndrome due to other causes were examined for complement concentration. A total of 80 samples were examined for C3 and 25 samples for C4 concentration using the immunediffusion plates. Almost all patients with A.G.N. and M.P.G.N. showed depression of C3. C4 concentration was normal except in 2 patients, 1 with A.G.N. and the other With M.P.G.N. This suggest activation of complement at the C3 level by the alternating pathway in most of the patients. C3 concentration in A.G.N. patients returned to normal after 8-10 weeks. In MPGN the depression was persistent in 2 patients, while in 1 patient it returned to normal level after 3 months of Immunosuppressive treatment.
Role of early education in reading ability of deaf students Bambang Udji Djoko Rianto
Paediatrica Indonesiana Vol 49 No 4 (2009): July 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (109.876 KB) | DOI: 10.14238/pi49.4.2009.189-94

Abstract

Background Reading is a very complex process which includescognitive process. Reading is initialized by visual analysis and lettertransformation into vocabulary form, word identification by lettersound mapping, words correlation, and interpretation. Deafnesscauses difficulties in acquiring language information via hearingprocess thus inhibits a successful conversation process.Objective To determine the role of early education in deaf students to reading ability.Methods A cross sectional design was performed from Septemberuntil December 2007. This study compared deaf students,younger than 6 years old, who received early education in specialeducation schools B (group I), with deaf children aged 6 years old and older who received education in special education schools B/conventional educational method (group II).Results There were 22 deaf children in group I and 24 in group II. The measured variables included age, age of school enrollment, duration of studies, degree of deafness, sex, and parental educational level. Logistic regression analysis showed that the variables which significantly contributed to reading skills were the early education and duration of study. In early education group, the children had significantly better reading ability (P=0.02; OR= 19.95; 95% CI 1.939 to 53.62), besides duration of study (P=O.Ol; OR=70.754; 95% CI 6.267 to 798.75), compared to conventional education.Conclussion Compared to those who receive education in specialeducation school B with a conventional educational method, deafstudents who receive early education in special education schoolsB have better reading ability significantly. Duration of studyalso contribute significantly to reading skill.
Parents Evaluation of Developmental Status and Denver Developmental Screening Test II in high risk infant and toddler Effie Koesnandar; Soedjatmiko Soedjatmiko; Pustika Amalia
Paediatrica Indonesiana Vol 50 No 1 (2010): January 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (283.657 KB)

Abstract

Background. Developmental screening is important particularly for high risk infants and toddlers. Parents Evaluation of Developmental Status (PEDS) and Denver Developmental Screening Test II (Denver II test) are recommended instruments with good sensitivity and specificity. Compared to Denver II test, PEDS is simpler, thus it is important to assess the agreement of PEDS and Denver II test.Objectives. To determine the prevalence of developmental disorder in high risk infants and toddlers and agreement of PEDS and Denver II test.Methods. Infants and toddlers registered at pediatric high risk clinic were recruited. PEDS questionnaire was answered by parents while the Denver II test performed by the investgator. Agreement of PEDS and Denver II instrument was assessed by Kappa score.Results. Out of 71 subjects, 41 (58%) were male, 43 (61%) were >12 months old, 35 (49%) were undernourished, 42 (59%) were preterm (<37 week gestational age), and 43 (60.6%) were low birth weight (LBW). The prevalence of developmental disorder was higher in subjects >12 months old (42%), undernourished (49%), preterm (48%), and LBW (47%). The prevalence of developmental disorder was 49% by PEDS and 39% by Denver II test. Agreement of PEDS and Denver II test was good with Kappa score 0.52, particularly for gross motor and language domain.Conclusions. The prevalence of developmental disorder is higher in high risk infant and toddler, who >12 months old, undernourished, premature, and LBW. PEDS instrument are equivalent to Denver II test, shows good agreement, particularly for gross motor and language domain. [Paediatr Indones. 2010;50:26-30].

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