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Paediatrica Indonesiana
Published by Ikatan Dokter Anak Indonesia
ISSN : 00309311     EISSN : 2338476X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.
Arjuna Subject : -
Articles 2,118 Documents
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The proportion of bone mineral density in children with high risk acute lymphoblastic leukemia after 6- and 12-month chemotherapy maintenance phase Mira Christiyani Santoso; Endang Windiastuti; Alan R. Tumbelaka
Paediatrica Indonesiana Vol 50 No 6 (2010): November 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (121.074 KB) | DOI: 10.14238/pi50.6.2010.365-70

Abstract

Background Low bone mineral density (BMD) value is one of the current concerns in acute lymphoblastic leukemia (ALL) patients. Some risk factors including use of chemotherapeutic drugs, nutritional status, phy sical activities, and progression of disease are suspected as the predisposing factors for development of osteopenia and osteoporosis.Objectives To obtain the proportion of BMD z-score, level of calcium ions, and 25 (OH)D3 in children 'With high risk ALL after 6 and 12 months chemotherapy maintenance phase.Methods We conducted a cross-sectional comparative study from May 2008 to May 2010. Subjects were high risk ALL patients aged 5-18 years old who had completed the 6 or 12 months chemotherapy maintenance phase. We measured 25 (OH) D3 level, calcium ion level, and BMD using electro chemi-luminescence immunoassay, ion selective electrode, and dual x-ray absorptiometry, respectively.Results There were 40 subjects who enrolled this study. The incidence of hypocalcemia and vitamin D deficiency were 33/40 and 40/40, respectively. The mean calcium ion levels, 25 (OH)D3 level, and BMD z􀁏score values in six months groups were 1.1 (0.1 SD) mmol/L, 21.3 (2 SD) ng/L, -0.7 (0.8 SD), respectively, while in the 12 months group, the values were 1.1 (0.0 SD) mmol/L, 21(2.2 SD) ng/L, -1.7 (0.6 SD), respectively (P=0.478). Body mass index (BMI) and corticosteroid cumulative dose is correlated \\lith the low BMD values in L1-L4.Conclusion The bone mineral metabolism disorder marked with the low levels of calcium, 25 (OH)D3 and osteopenia was observed in ALL patients who underwent chemotherapy. The proportion of the BMD z-score value, calcium ion level, and 25 (OH) D3 in the two groups were not statistically significant.
Duration of watching TV and child language development in young children Silva Audya Perdana; Bernie Endyarni Medise; Erni Hernawati Purwaningsih
Paediatrica Indonesiana Vol 57 No 2 (2017): March 2017
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (225.599 KB) | DOI: 10.14238/pi57.2.2017.99-103

Abstract

Background Many factors contribute to language development in children. About 5-8% of children in Indonesia experience delayed language skills. Young children need appropriate stimulation for optimal development. Children who watch television (TV) for long periods of time may receive less two-way interaction, the appropriate stimulation for learning. As such, shorter duration of the appropriate stimulation may impede language development in small children.Objective To assess for an association between duration of watching TV and language development in young children.Methods This cross-sectional study was done with primary data collected from questionnaires. Subjects, aged 18 months to 3 years, were from a Jakarta-area community health center (Puskesmas) Jatinegara and the Pediatric Growth and Development Clinic, Cipto Mangunkusumo Hospital, Jakarta. Their language development was tested using the Developmental Pre-screening Questionnaire (Kuesioner Pra Skrining Perkembangan, KPSP) and the Early Language Milestone (ELM Scale 2) test.Results From a total of 84 subjects, 47 (56%) had normal and 37 (44%) had delayed language development. Duration of watching TV was categorized as <4 hours per day or >4 hours per day. Children who watched TV >4 hours/day (OR 4.4; 95%CI 1.68 to 11.7; P=0.002), and children who watched both Indonesian and English language TV programs (OR 14.7; 95%CI 1.77 to 123.0; P=0.004) had higher risk of language delay. Other variables such as sex, first age exposed to TV, use of gadgets, and TV in the bedroom had no significant associations with delayed language development.Conclusion Children who watch TV >4 hours/day had four times higher risk of developing language delay. In addition, those who watch TV programs in both Indonesian and English, also have a 14.7 higher risk of delayed language development.
Congenital Anomaly Caused by Cytomegalovirus and Toxoplasma Infections Sunartini Noormanto
Paediatrica Indonesiana Vol 36 No 5-6 (1996): May - June 1996
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi36.5-6.1996.121-5

Abstract

We report a case of a five-year-old child with congenital anomaly caused by maternal cytomegalovirus infection and toxoplasmosis, hospitalized in pediatric ward Sardjito General Hospital. The diagnosis was established from the history of illness, physical examination, and laboratory findings. The presence of microcephaly, failure to thrive, deaf and mute, congenitally transmitted infection was suspected.
Prevalence of urinary tract infection in 2-8-week-old infants with jaundice Partini Trihono; Arfianti Chandra Dewi; Hartono Gunardi; Hanifah Oswari
Paediatrica Indonesiana Vol 52 No 5 (2012): September 2012
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (103.902 KB) | DOI: 10.14238/pi52.5.2012.304-8

Abstract

Background Urinary tract infections (UTI) in infants may manifest in various ways and often appear without symptoms. Previous studies have reported that j aundice has been observed in infants aged less than 8 weeks 'With UTIs. However, a prospective study on the prevalence of UTI in infants with jaundice aged 2􀁂8weeks is warranted in order to improve diagnosing capability and provide prompt treatment.Objective To investigate the prevalence and profiles of UTI in infants with jaundice aged 2􀁂8 weeks.Methods This cross􀁂sectional study was carried out in June-December 2011 in infants with jaundice aged 2􀁂8 weeks. Subjects were patients from the Department of Child Health, Cipto Mangunkusumo Hospital (CMS), as well as the Pediatric Polyclinics ofBudi Kemuliaan and Thamrin Hospitals. All subjects underwent total, direct and indirect bilirubin examinations, urinalyses and urine cultures.Results Of the 110 subjects recruited, the prevalence of UTI was 18.2%. More boys than girls had UTIs (13 boys, 7 girls). The microorganisms found in subjects v.ith UTIs were Escherichia coli (10/20), Klebsiella pneumoniae (8/20), and Enterobacter aerogenes (2120). Indirect hyperbilirubinemia was found in 5/20 subjects. There were more subjects with UTIs in the non􀁂exclusively breastfed (8/20) and non􀁂breastfed (8/20) groups than in the exclusively breastfed group (4/20), the full term gestational age (GA) group (17/20) than the pretenn GA group (3/20), and the normal birth weight group (15/20) than the low birth weight group (5/20). The median age of jaundice onset was 3.5 days (range lAO days), and the median duration of jaundice was 13.5 days (range 3-56 days).Conclusion The prevalence of UTI in infants aged 2􀁂8 weeks v.ith jaundice was 18.2%. More boys than girls had UTIs. The most common infecting microorganism found in our subjects was Escherichia coli. In daily medical practice, infants with prolonged jaundice of more than 2 weeks should be tested byurin alysis and urine cultures for the presence of UTIs. [Paediatr Indones.2012;52:304-8].
Prognostic factors for success in the Kangaroo Mother Care method for low birth weight babies Rina Pratiwi; Muhammad Sholeh Kosim; Noor Wijayahadi
Paediatrica Indonesiana Vol 55 No 3 (2015): May 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (259.134 KB) | DOI: 10.14238/pi55.3.2015.142-6

Abstract

Background Low birth weight (LBW) is closely related to neonatal morbidity and mortality. Management of LBW infants in developing countries remains limited, due to the low availability of incubators. The Kangaroo Mother Care (KMC) method has been shown to be effective for newborns, especially LBW infants, in which skin-to-skin contact may be conducive for infants’ weight gain, thermoregulation, and heart rate stability.Objective To determine the prognostic factors for KMC success in LBW babies.Methods This cohort study included LBW infants at Dr. Kariadi General Government Hospital, Semarang, by a consecutive sampling method. Success of KMC was assessed by infant weight gain, as well as stabilization of temperature, heart rate, and respiration. Prognostic factors for KMC success that we assessed were birth weight, gestational age, KMC duration, age at KMC onset and maternal education level. Statistical analyses used were Chi-square and relative risk (RR) tests.Results Of 40 LBW infants, 24 were successful in KMC. Birth weight ≥ 1500 grams (RR 0.4; 95%CI 0.23 to 0.73; P=0.001)], gestational age ≥ 34 weeks (RR 0.94; 95%CI 0.46 to 1.89; P=1.00), KMC duration ≥ 65 minutes (RR 1.44; 95%CI 0.76 to 2.75; P= 0.215), high maternal education level (RR 1.25; 95%CI 0.76 to 2.04; P=0.408), and age at KMC onset >10 days (RR 2.69; 95%CI 1.14 to 6.32; P=0.003), were factors that related to the successful of KMC.Conclusion Age at KMC onset > 10 days was a prognostic factor for KMC success in low birth weight babies.
Influence of educative game instrument on children's motor development in child day care Lucie Permana Sari; Sri Sofyani; Bistok Saing; Iskandar Z. Lubis
Paediatrica Indonesiana Vol 48 No 6 (2008): November 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (123.69 KB) | DOI: 10.14238/pi48.6.2008.315-21

Abstract

Background Child day care center is an institution functioning tohelp families to fulfil their child's need by providing stimulation witheducative game instrument (EGI) while they work outside home.Objectives To evaluate motor development of children at child daycare center with EGI stimulation compared with that of childrenwithout stimulation.Methods An experimental study using pretest-posttest control groupdesign was cartied out on children aged 2 to 5 years old, at Islamic CenterDay Care Center (without EGI) and Tanah-Besi Day Care Center inTebing Tinggi (with EGI for six months). Inclusion criteria: healthy,well-nourished children aged 2 to 5 years with informed consent, nodevelopmental delay (confirmed by Denver-II developmental screeningtest). Exclusion criteria: pre term birth children. Forty subjects wereselected by means of simple random sampling. Research data weretaken with Cronbach's motor skills scale. Subjects consisted of 3 to 4years old children, mostly four years old.Results Motor skills scores (mean; SD) of the Islamic CenterDay Care Center group and Tanah-Besi Day Care Center groupbefore stimulation were 104.9; 10.37 and 104.7; 5.47 (P=0.923),respectively, and after stimulation 105.2; 9.56 and 135.3; 7.67 (P<0.001), respectively. Motor skills scores (mean; SD) of Tanah-BesiDay Care Center group before and after stimulation were 104.7; 5.4 7and 135.3; 7.67 (P< 0.001) respectively. Motor skill dimensions score(mean; SD) ofTanah-Besi Day Care Center group before and afterstimulation: speed 28.9; 1.75 and 38.8; 2.79, stability 22.3; 1.02 and30.6; 1.57, accuracy 20.3; 1.15 and 26.7; 1.63, strength 33.3; 1.55and 39.1; 1.68, respectively with P< 0.001.Conclusions There is a significant difference in motor skillsscores and motor skill dimensions of children who receive EGIstimulation compared to those who do not.
Hemolytic uremic syndrome and hypertensive crisis post dengue hemorrhagic fever: a case report Mervin Tri Hadianto; Omega Mellyana
Paediatrica Indonesiana Vol 51 No 6 (2011): November 2011
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi51.6.2011.372-6

Abstract

Hemolytic-uremic syndrome (HUS) clinically manifests as acute renal failure, hemolytic anemia and thrombocytopenia. Acute renal failure with oliguria, hypertension, and proteinuria usually develops in affected patients.1,2 In children under 15 years of age, typical HUS occurs at a rate of 0.91 cases per 100,000 population.3 The initial onset of this disease usually happens in children below 3 years of age. Incidence is similar in boys and girls. Seasonal variation occurs, with HUS peaking in the summer and fall. In young children, spontaneous recovery is common. In adults, the probability of recovery is low when HUS is associated with severe hypertension.2
Deferiprone effectiveness in thalassemia major children with or without hepatitis B or C virus infection: a non-randomized study Yovita Ananta; Pustika Amalia Wahidiyat; Hanifah Oswari
Paediatrica Indonesiana Vol 50 No 2 (2010): March 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi50.2.2010.105-12

Abstract

Background A high incidence rate of hepatitis B or C virusinfection is found among thalassemia children in Indonesia. Thismay influence deferiprone effectiveness.Objective To determine the effectiveness of deferiprone inthalassemia children with or without hepatitis B or C virusinfection.Methods A non-randomized clinical study was performed atThalassemia Center Jakarta. Subjects were thalassemia childrenwith serum ferritin level > 1000 ng/mL who had hepatitis B orC virus infection. A match control pair was recruited based onsimilar duration of transfusion therapy, thalassemia type, andinitial serum ferritin level. All subjects received initial deferipronedose of 50 mg/kg/day for 3 months. Those whose ferritin decreased2:: 10% continued to receive deferiprone of 50 mg/kg/day for thefollowing 3 months. Otherwise, deferiprone dose was adjustedto 75 mg/kg/day.Results Forty-eight subjects were recruited. After 3 months oftreatment, 16/24 subjects without and 6/24 subjects with hepatitisB or C had their ferritin level decreased 2:: 10%. Mean ferritinserum level of all subjects after 6 months was significantly reducedfrom 4734 (SD 2116) to 3695 (SD 1709) ng/mL. Lower meandeferiprone dose, lower mean post- study ferritin serum level andhigher mean percentage of ferritin serum level decrement werefound in subjects without hepatitis B or C infection than thosewith infection.Conclusions Deferiprone 50-7 5 mg/kg/day for 6 months is effectivein reducing serum ferritin level of thalassemia major children; itis more effective in thalassemia children without hepatitis B or Cvirus infection.
Cholera El Tor in Infants below 2 Years of Age as seen in Private and Hospitalized Patients Haroen Noerasid; Pitono Soeparto; Bing Rudianto; Hananto Wirjo; Juliati Sudanawidjaja; Soeharjono Padmodiwirjo
Paediatrica Indonesiana Vol 19 No 3-4 (1979): March - April 1979
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (225.041 KB) | DOI: 10.14238/pi19.3-4.1979.79-83

Abstract

A report was made on cholera El Tor in children under 2 years of age with mute gastroenteritis admitted to the pediatric ward of the Dr. Soetomo Hospital, Surabaya. Twenty-three out of 115 cases (20%) showed positive stool cultures. A similar report was made in the same period on patients with gastroenteritis in private practice. Four out of 108 cases (3.6%) showed positive stool cultures. A brief description of the disease pattern of infantile gastroenteritis was presented. The increasing incidence of cholera, below one year was also discussed.
Leptin, blood pressure, and left ventricular mass in obese adolescents David Kaunang; Handri Widodo; Vivekenanda Pateda
Paediatrica Indonesiana Vol 53 No 6 (2013): November 2013
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (102.245 KB) | DOI: 10.14238/pi53.6.2013.346-9

Abstract

Background Obesity is characterized by an excessive accumulationof body fat and has become a major health problem in industrializedsocieties especially with regards to heart disease. Adipose tissuederived hormone (leptin) can cause obesity. Leptin acts to reducefood consumption and enhance energy expenditure.Objective To assess for a relationship between leptin, bloodpressure, and left ventricular mass in obese adolescents.Methods This was a cross-sectional study conducted fromNovember 2011 to April 2012 in Prof. Dr. RD. Kandou Hospital.This study included obese and healthy adolescents aged 13-18years who attended school in Tuminting District ofManado. Eachsubject underwent measurements of body mass index (BMI), booldpressure, and plasma leptin level. Correlation regression test wasused for data analysis. Results were considered to be statisticallysignificant if P values < 0.05.Results There was a significant relationship between leptin andleft ventricular mass (r=-0.467; P=0.006), as well as leptin andsystolic blood pressure (r=-0.366; P=0.028), but not betweenleptin and diastolic blood pressure (r=-0.261; P=0.09). We alsofound significant relationships between systolic blood pressure andleft ventricular mass (r=0.724; P<0.001), and between diastolicblood pressure and left ventricular mass ( r=0.615; P< 0.001) inobese adolescents.Conclusion Higher leptin levels are associated with lower leftventricular mass and lower systolic blood pressure, but are notassociated with diastolic blood pressure.

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