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Paediatrica Indonesiana
Published by Ikatan Dokter Anak Indonesia
ISSN : 00309311     EISSN : 2338476X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.
Arjuna Subject : -
Articles 2,118 Documents
 36   37   38   39   40 
Bacterial endocarditis in children: clinical and laboratory findings, and the role of echocardiography in its diagnosis and management Sudigdo Sastroasmoro; Bambang Madiyono; Ismet N. Oesman; Sukman Tulus Putra
Paediatrica Indonesiana Vol 29 No 9-10 (1989): September - October 1989
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi29.9-10.1989.188-98

Abstract

We report clinical and laboralory findings of 15 children with bacterial endocarditis, admitted ro the Department of Child Health, University of Indonesia/Cipto Mangunkusumo Hospital from February, 198710 June, 1989.There were 8 boys and 7 girls with bacterial endocarditis, ranging in age from 10 weeks 10 16 years. The diagnosis was suspected because of prolonged fever, with or without other manifestations, i.e. congestive heart failure, refractory anemia, or paroxysmal atrial tachycardia. The underlying heart disease was congenital in 12 cases and rheumatic heart disease in 3 cases.The clinical, electrocardiographic, and radiologic manifestations were generally predominated by the pre-existing heart disease. No characteristic findings of bacterial endocarditis, i.e. Osler's nodes, Janeway lesions or splinter haemorrhages were detected.Positive bacterial culture was obtained in 12 cases; the most frequent bacteria isolated was Pseudomonas aeruginosa (4 cases), Streptococcus viridans was isolated in 2 cases only.Vegetation was visualized echocardiographically in 12 cases; 9 with clear cut evidence of large vegetation, and the other 3 the vegetation was equivocal. On follow-up they disappeared gradually with clinical improvemenl. Large vegetation might need 2 full months 10 disappear echocardiographically.
Salmonella Meningitis in the Newborns and Young Infants in Jakarta, Indonesia Sumarmo Sumarmo; Muslim A. Nathin; Sofyan Ismael; W. A. F. J. Tumbelaka
Paediatrica Indonesiana Vol 22 No 9-10 (1982): September - October 1982
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi22.9-10.1982.185-94

Abstract

Experience with salmonella meningitis in the newborn and young infantsbelow the age of 40 days hospitalized during the period 1976- 1979 was described. They constituted 8.6% of the 324 cases of purulent meningitis in children in approximately 20.000 admissions in the 4-year-period. There was a preponderance of males among the patients and the youngest case was 2 days old. The Salmonella serotypes isolated from cerebral spinal fluid were havana ( 17 cases J and oranienburg (11 cases). Of particular interest is the fact that 4 of the infants and their mothers showed the identical offending organisms isolated from the spinal fluid and rectal swab. The most common predisposing maternal obstetric complicationswere fever and premature rupture of the amniotic membranes, whereas the predisposing factors in the infants were infections, asphyxia arul prematurity. Ventriculitis, subdural effusion/empyema and hydrocephalus were the most common complications. A brief discussion has been made on the appropriate time to perform ventricular tap.
Detection of the jaundice-related G71R mutation in the UGT1A1 gene by denaturing high performance liquid chromatography (DHPLC) Retno Sutomo; Sunartini Hapsara; Suryono Yudha Patria; Hajime Nakamura
Paediatrica Indonesiana Vol 49 No 1 (2009): January 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (172.816 KB) | DOI: 10.14238/pi49.1.2009.1-6

Abstract

Background  The  G71R mutation in the UGT1A1 gene has  beenassociated with neonatal jaundice  and  other  cases  of  hereditary,unconjugated hyperbilirubinemia in several Asian populations.Currently,  DNA  sequencing  is  the  only  method  available  toidentify the mutation, which can be time- and  labor-intensive,particularly for such projects  as  population-based genetic studies.A relatively new method, denaturing high performance liquidchromatography (DHPLC),  is  increasingly used to  detect  variousmutations.Objective  The  aim  of  the present study was to investigate theability of DHPLC to  detect  the G71R mutation, in comparisonwith the gold standard of sequencing analysis.Methods Seventy-two infants were enrolled. Following genomicDNA  extraction, exon 1 of the UGT1A1 gene was amplified  bypolymerase chain reaction (PCR). Afterwards, the G71R mutationwas simultaneously,  and  blindly, determined in all subjects  byDHPLC and sequence analysis.  The  performance  of  the DHPLCanalysis, compared  to  the sequence analysis, was assessed in termsof  sensitivity  and  specificity.Results DHPLC detected the G71 R mutation in  31  individuals.Of  these,  26  were heterozygous and 5 were homozygous for themutation. This method did not find the mutation in  41  otherindividuals. Sequence analysis produced identical results for allindividuals.Conclusion DHPLC analysis  is  capable  of  detecting the G71Rmutation  in  the  UGT1A1  with  a degree  of  sensitivity  andspecificity  (100%  each)  that  is  comparable to sequencing analysis.
Pattern and influencing factors of breastfeeding of working mothers in several areas in Jakarta Rifan Fauzie; Rulina Suradi; Sri Rezeki S. Hadinegoro
Paediatrica Indonesiana Vol 47 No 1 (2007): January 2007
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (347.446 KB) | DOI: 10.14238/pi47.1.2007.27-31

Abstract

Background Breast milk contains many essential nutrition factorsbest for babies. The 1997 Indonesian Health Demography foundthat the proportion of exclusive breastfeeding was still low (52%)and increased to 55.1% in 2002. Due to increasing number ofworking mothers, promoting breast feeding among them should beperformed properly. There are no data on exclusive breastfeedingrate and pattern among working mothers in Indonesia.Objective To describe exclusive breastfeeding rate and patternamong working mothers in several areas in Jakarta and the influ-encing factors.Methods A descriptive study using a questionnaire was conductedfrom October 2005 to February 2006. Subjects were workingmothers who had 6 to 12 month old baby and breastfed and thebaby had no congenital or chronic disease.Results Among 290 mothers interviewed, 40% worked at banksor insurance business, 34% were private employees, 25% medicalstaffs, and 2% were teachers. Almost 80% have exclusivelybreastfed for less than 4 months, 17% for 4 months, and only 4%for 6 months. Maternal leave, family support, mothers’ knowl-edge, facilities at workplace, media influences, and working hoursseemed to have no relations to breastfeeding rate. There were122 (42%) mothers who had good knowledge about physiologyof lactation, 155 of them (53%) had fair knowledge, and only45% of them had poor knowledge.Conclusions The proportion of working mothers in several areasin Jakarta who have exclusively breastfed for 4 months is 17%, andonly 4% of subjects do exclusive breastfeeding for 6 months. Mostsubjects have a good to fair knowledge about the physiology oflactation but it does not seem to influence the decision to exclu-sively breastfed their babies.
The risk of early-onset neonatal sepsis in preterm infants with maternal histologic chorioamnionitis IGK Winata Adnyana; Soetjiningsih Soetjiningsih
Paediatrica Indonesiana Vol 45 No 4 (2005): July 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi45.4.2005.160-5

Abstract

Background Chorioamnionitis, usually a subclinical condition, maycause preterm delivery and long-term morbidity.Objective The objective of this study was to determine the risk ofearly-onset neonatal sepsis in preterm infants with maternal histo-logic chorioamnionitis (HCA).Methods This was a prospective cohort study of preterm infantsborn at Sanglah Hospital, Denpasar from September 2002 to Feb-ruary 2004. Histopathological examinations of the subjects’ placen-tas were done and the infants were monitored for 72 hours for clini-cal signs of early-onset neonatal sepsis. Maternal and neonatal riskfactors were analyzed using multivariate statistical analysis.Results Eighty-two preterm infants were included, of which 41 werepositive for maternal HCA. Twenty-five (61%) of the infants posi-tive for maternal HCA developed early-onset neonatal sepsis, com-pared to 5 (12%) of those negative for maternal HCA (RR=5, 95%CI2.12;11.78). Nine infants died from early onset neonatal sepsis.Eight of them had positive HCA, and only one had negative HCA.The average length of hospital stay between infants with and with-out maternal HCA did not differ significantly [12.0 (SD 5.08) vs.12.6 (SD 1.34); P=0.80]. Logistic regression model analysis iden-tified only HCA as a significant risk factor for early-onset neonatalsepsis (OR=6.9, 95%CI 2.0;23). Gestational age (OR=1.3, 95%CI0.8;2.0), birth weight (OR=1.0, 95%CI 0.9;1.0), and neonatal as-phyxia (OR=1.0, 95%CI 0.1;4.4) were not found to be significantrisk factors.Conclusion Preterm infants with maternal histologicchorioamnionitis are at a higher risk for developing early-onsetneonatal sepsis
Tuberculous mastoiditis in children K. U. Mugiyo; N. N. Rahayoe; H. H. Hendarto
Paediatrica Indonesiana Vol 21 No 5-6 (1981): May - June 1981
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi21.5-6.1981.125-31

Abstract

The authors emphasized that though up till now such cases are still unfrequently encountered one should always be aware that tuberculous mastoiditis in infants and young children has quite high prevalence.
The Use of Medium-Chain Triglyceride in Children with Intestinal Malabsorption Michael Gracey
Paediatrica Indonesiana Vol 14 No 7-8 (1974): July - August 1974
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (818.392 KB) | DOI: 10.14238/pi14.7-8.1974.113-7

Abstract

The comments which followare a brief summary of the thera-peutic place of MCT in children withmalabsorption. This will be followedby some remarks about the potentialvalue of MCT in countries like Indo-nesia where the commonest cause ofchronic diarrhoea and malabsorptionin children is malnutrition and chro-nic and repeated gastrointestinal in-fections and infestations and whereMCT has not been used widely.
Effect of kangaroo method on the risk of hypothermia and duration of birth weight regain in low birth weight infants: A randomized controlled trial I G. A. P. Eka Pratiwi; Soetjiningsih Soetjiningsih; I Made Kardana
Paediatrica Indonesiana Vol 49 No 5 (2009): September 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (115.801 KB) | DOI: 10.14238/pi49.5.2009.253-8

Abstract

Background In Indonesia, the infant mortality rate in 2001 was 50 per 1000 live births, with 34.7% due to perinatal death. This perinatal death was associated with low birth weight (LBW) newborn, which was caused by prematurity, infection, birth asphyxia, hypothermia, and inadequate breast feeding. In developing countries, lack of facilities of LBW infant care leads to the utilization of kangaroo method as care to prevent hypothermia in LBW newborn.Objective To evaluate the differences of hypothermia event andduration of birth weight regain in LBW newborns between earlykangaroo care (EKC) and conventional care (CC).Methods This was an open label randomized controlled trial. The1500-2250 g LBW newborns who were born in Sanglah Hospitalwere randomized to EKC and CC groups.Results Hypothermia events were found more often in CC groupthan EKC group (RR=0.645, 90% CI 0.45 to 0.92, P=0.05). Thisdifference was influenced by breast feeding frequency. Duration of birth weight regain in EKC group (median 5 days (SE=0.31, 90% CI 4.49 to 5.51) was shorter than CC group (median 6 days (SE=0.52, 90% CI 5.15 to 6.85), but this difference wasn't statistically significant (P=0.40). Percentage of birth weight decrease, breastfeeding frequency, and hyperbilirubinemia events that needed phototheraphy were associated with the duration of birth weight increase.Conclusion EKC helps to decrease the incidence of hypothermiaevents, but fails to shorten duration of birth weight increase.Percentage of birth weight decrease, breast-feeding frequency, and hyperbilirunemia events that need phototheraphy are associated with the duration of birth weight increase in LBW newborn.
Correlations between hemoglobin, serum ferritin, and soluble transferrin receptor levels in children aged 6-59 months Fajar Diah Tri Kusumastuti; Sutaryo Sutaryo; Sri Mulatsih
Paediatrica Indonesiana Vol 54 No 2 (2014): March 2014
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (150.787 KB) | DOI: 10.14238/pi54.2.2014.122-6

Abstract

Background Early detection of iron deficiency is important in young children to prevent iron deficiency anemia, which may cause permanent neurocognitive development disorders. Hemoglobin level is an insensitive tool for detecting iron deficiency without anemia, while serum ferritin levels may be influenced by infection and inflammation. However, soluble transferrin receptor (sTfR) is a sensitive marker for detecting iron deficiency, yet not widely used in daily practice.Objective To assess for correlations between hemoglobin, serum ferritin, and soluble transferrin receptor levels in children aged 6-59 months.Methods We performed a cross-sectional study in the Yogyakarta and Bantul Districts involving 85 children aged 6-59 months who visited integrated health posts (posyandu) and who met the inclusion criteria. Subjects were chosen by cluster random sampling. Blood specimens were collected to examine hemoglobin, serum ferritin, and sTfR levels.Results Spearman’s correlation test revealed weak negative correlations between hemoglobin and serum ferritin levels, as well as between hemoglobin and sTfR levels, with coefficient correlations of r = -0.220, (P=0.043) and r = -0.317, (P=0.003), respectively. There was no correlation between serum ferritin and sTfR levels (r = -0.033; P=0.767).Conclusion Hemoglobin levels has weak negative correlations with serum ferritin and sTfR, but serum ferritin does not correlate with sTfR. [Paediatr Indones. 2014;54:122-6.]
The relation of BCG vaccination and severe malnutrition with the occurrence of tuberculous meningitis Nofareni Nofareni; Bistok Saing; Ridwan M. Daulay; Bidasari Lubis
Paediatrica Indonesiana Vol 44 No 1 (2004): January 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (329.984 KB) | DOI: 10.14238/pi44.1.2004.12-6

Abstract

Objectives To assess BCG vaccination and nutritional states inchildren with tuberculous meningitis and their relations with theoccurrence of tuberculous meningitis.Methods A case-control study was conducted at the Divisionof Neurology, Department of Child Health, Adam Malik Hospi-tal, Medan, from January 1997 to December 2000. Subjects ofthis study were all tuberculous meningitis patients and primarytuberculosis patients as the control group. Odds ratio (OR) wasused to assess the risk of tuberculous meningitis in patientswith positive BCG vaccination and (1-OR) was used to assessthe efficacy of BCG to prevent tuberculous meningitis.Results Four out of sixteen tuberculous meningitis patients werevaccinated, while 10 of 16 primary tuberculosis patients were vac-cinated (p=0.03). OR of vaccinated patients to get tuberculousmeningitis was 0.2 (95%CI 0.04;0.91). The efficacy of BCG vacci-nation to prevent tuberculous meningitis was 1-0.2 = 0.8. The riskof severe malnourished patients to get tuberculous meningitis was2.33 (95%CI 0.52;10.48; p=0.26).Conclusion Most tuberculous meningitis patients were not BCGvaccinated. Severe malnutrition did not play role in the occurrenceof this disease

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