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Paediatrica Indonesiana

paediatrica-indonesiana
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Published by Ikatan Dokter Anak Indonesia

ISSN : 00309311 EISSN : 2338476X DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology

Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.

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Articles 2,118 Documents

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Impact of Bifidobacterium lactis supplementation on fecal microbiota in infants delivered vaginally compared to Caesarean section Tetty Yuniaty; Fiva Kadi; Hadyana Sukandar; Mifta Novikasari; Pensri Kosuwon; Enea Rezzonico; Paiboon Piyabanditkul; Leilani Lestarina; Marco Turini
Paediatrica Indonesiana Vol 53 No 2 (2013): March 2013
Publisher : Indonesian Pediatric Society

Background It has been reported that infants born by Caesareansection have altered gut microbiota, with lower n umbers ofbifidobacteria and Bacteroides, compared to that of infants whowere delivered vaginally. Probiotic supplementation has beenreported to have beneficial effects on the immune response,generally in relation to allergies.Objective To assess the effect of Bifidobacterium lactis (B. lactis)supplementation on the presence of B. lactis and bifidobacteriacounts in stool of infants during the first 2 months of life .Methods We conducted an observational study of 122 healthy,breast-fed infants delivered vaginally or by Caesarean section.Infants assigned to the test group received breast milk and formulasupplemented with the B. lactis probiotics. Infants in the controlgroup received breast milk and formula without probiotics.The presence of B. lactis and stool bifidobacteria counts weredetermined at 1 month and 2 months of age. Growth, morbidity,serum immune markers, and stool immunoglobulin (lg) A werealso assessed.Results B. lactis was more frequently detected in the stool ofinfants who received breast milk and probiotic-supplementedformula than in stool of infants who received breast milk andnon-supplemented formula, both at 1 month and 2 months ofage (OR 1,263; 95%Cl 11 to 15 1,030; P=0.003) . Of infants whoreceived probiotic-supplemented formula, B. lactis was detected in80% of those delivered by Caesarean section and in 3 8% of thosedelivered vaginally, at the 1-month mark. In infants delivered byCaesarean section, the mean stool bifidobacteria level at 1 monthwas significantly higher in the probiotic-supplemented groupcompared to that of the non-supplemented group (P=0.021) .Conclusion Early bifidobacteria supplementation of infants,particularly those delivered by Caesarean section, is associatedwith higher levels of stool bifidobacteria. Anthropometric datasuggests beneficial effect s of bifidobacteria supplementationon infant growth, though most are not statistically significant.

Factors associated with shock in children with dengue hemorrhagic fever Erick F Kan; T H Rampengan
Paediatrica Indonesiana Vol 44 No 5 (2004): September 2004
Publisher : Indonesian Pediatric Society

Background Shock in dengue hemorrhagic fever (DHF) still con-stitutes an important problem in children. Predicting DHF patientswho will develop shock is difficult.Objective The aim of this study was to find out factors associatedwith shock in DHF.Methods This was a prospective observational study. Subjectswere children hospitalized from April to July 2000 who met theWHO criteria for DHF and had positive serological confirmation.Association between independent variables (age, gender, dura-tion of fever, abdominal pain, vomiting, hepatomegaly, plateletcount, hematocrit level, and nutritional status) and the dependentvariable (shock) was analyzed by logistic regression model..Results There were 85 children who met the eligibility criteriaconsisting of 50 (59%) boys and 35 (41%) girls with an averageage of 7.1 years (SD 2.88). Shock occurred in 42 (49%) children.Of the 42 children with shock, the age group of 5-9 years madeup the biggest group (57%) consisting of 23 (55%) boys and 19(45%) girls. Hepatomegaly was found in 32 (76%) children, ab-dominal pain and vomiting in 30 (71%) and 36 (86%) children,respectively, and good nutrition in 22 (52%) children. Shock oc-curred mainly on the fourth and fifth days (76%). Almost half ofthe patients (45% and 52%) had hematocrit level of 46-50% andplatelet count of 20,000-50,000/ml, respectively. By logistic re-gression analysis, it was found that duration of fever, abdominalpain, hematocrit level, and platelet count constituted indepen-dent factors correlating with shock in DHF.Conclusion Abdominal pain, fever lasting four to five days, hema-tocrit level of >46%, and platelet count of <50,000/Î¼l were associ-ated with shock in DHF

Albendazole versus combined pyrantel pamoate-mebendazole in the treatment of mixed infection of soil-transmitted helminthiasis Tiangsa Sembiring; Evi Kamelia; T. Ernalisna; Syahril Pasaribu; Chairuddin P. Lubis
Paediatrica Indonesiana Vol 42 No 11-12 (2002): November 2002
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi42.6.2002.268-72

Background Soil transmitted helminthiasis is still highly prevalent in Indonesia, especially in rural area and among poor socio-economic population. Helminthiasis is frequently found as a single or mixed infection. It is difficult to get a medication with better efficacy, low cost, and simple administration for all types of worms.Objective The aim of this sudy was to compare the effectiveness of albendazole and pyrantel pamoate-mebendazole combination in treating soil-transmitted helminthiasis.Methods A randomized clinical trial was perionned in September until November 1995 on students of a primary school in Tanjung Anom Village whose stool examinations showed mixed infection of helminthiasis. Subjects were randomly allocated into two groups. The A group was treated with 400 mg oral albendazole as a single dose, while the B group was treated with the combination of pyrantel pamoate 10 mg/kg body weight as a single dose and mebendazole 100 mg twice a day for three consecutive days. Cure was considered if in the stool examination, no wonn eggs were found. Statistical analysis was periormed by Chi-square test with confidence interval of 95% and p value of < 0.05 was considered significant.Results Out of 541 children, mixed infection of soil-transmitted helminthiasis was found in 374 children (69%). Three hundreds sixty-six children completed the study, consisted of 182 children in group A and 184 in group B. At 3 weeks after treatment, the cure rate in the A group was significantly better compared to that in B group.Conclusions Albendazole was more effective than the combination of pyrantel pamoate - mebendazole for treating mixed infection of soil-transmitted helminthiasis. Besides the administration was simpler and caused minimal side effect.

Incidence of Cholera in Children under two years of age at the Dr. Soetomo Hospital, Surabaya Haroen Noerasid; Pitono Soeparto; Bing Rudyanto; Moh. Sjaifullah Noer; Moh. Adnan
Paediatrica Indonesiana Vol 15 No 7-8 (1975): July - August 1975
Publisher : Indonesian Pediatric Society

Stool cultures from 510 patients, admitted to the Children's Ward of the Dr. Soetomo Hospital with gastroenteritis, were examined. Fifty-six cases were found to have para Cholera El Tor (10.98%) and 56 patients showed positive E. coli (10.98%). The clinical features of para Cholera El Tor have been discussed, and compared with E. coli infections. We also reviewed the clinical observations of other writers. Clinically Cholera El Tor and E. coli have similar signs and symptoms. They differ only in: (a) Age (El Tor is usually found in older age groups). (b)Nutritional State (El Tor is found among the undernourished), (c) State of dehydration (El Tor causes dehydration more rapidly), and (d) Faeces (El Tor excretes more faeces per movement).

Food hypersensitivity as a cause of atopic dermatitis Hendra Santoso
Paediatrica Indonesiana Vol 37 No 9-10 (1997): September - October 1997
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi37.9-10.1997.208-15

Food hypersensitivity as a cause of atopic dermatitis.

Total serum IgE levels in soil-transmitted helminth infected children with atopy symptoms Hendri Wijaya; Lily Irsa; Supriatmo Supriatmo; Sjabaroeddin Loebis; Rita Evalina
Paediatrica Indonesiana Vol 54 No 3 (2014): May 2014
Publisher : Indonesian Pediatric Society

Background High total serum immunoglobulin E (IgE) levelsand eosinophilia are markers for atopy, but other factors mayalso play a key role in affecting atopy, such as intestinal parasiticinfection. Helminthiasis has been associated with a reduced riskof atopy and asthma symptoms in areas with high prevalence ofparasitic infections.Objective To assess for associations between total serum IgElevel and soil-transmitted helminthiasis (STH) infection, as wellas between STH infection and allergy symptoms.Methods We conducted a cross-sectional stu dy on 84consecutively-enrolled children , aged 7- 13 years, in theSecanggang Subdistrict, Langkat District, North SumateraProvince. Subjects were enrolled into one of two groups, with orwithout STH infection. Total serum IgE measurements and stoolSTH examinations were performed in all subjects. Data on atopyor allergy symptoms were obtained by parental interview.Results The 42 subjects with STH infection had significantlyhigher mean total serum lg E levels than the 42 subjects withoutinfec tion, 1,13 1.26 IU/mL and 744.76 IU/mL, respectiv ely(P = 0.029). We also fo und significant positive association sbetween STH infection and asthma symptoms (P= 0.049), as wellas eczema symptoms (P=0.044).Conclusion Mean total serum IgE level is higher in STHinfectedsubjects than in those without infection. In addition,STH infection is positively associated with asthma and eczemasymptoms.

Prevalence of dysfunction in sensory integration in kindergarten children Sem S. Surja; Hendry Irawan; Theresia Ilyan; Jessica Fedriani; Satyadharma M. Winata; Irene Irene
Paediatrica Indonesiana Vol 53 No 4 (2013): July 2013
Publisher : Indonesian Pediatric Society

Background Children with dysfunction in sensory integration(DSI) have difficulty effectively and efficiently interacting withtheir environment. It has been estimated that 5 to 10% ofchildrenwithout disabilities have DSI. Late assessment and interventionin children with this problem may significantly impact furtherdevelopment. To date, there is no available data on DSI prevalencein Indonesian children, which is crucial for better understandingof the DSI burden in the community.Objective To estimate the prevalence of DSI in North Jakartachildren using standardized screening tools.Methods Parents of kindergarten children from two privateschools in N orth Jakarta were given questionnaire packetsincluding the Family Information Questionnaire and Winnie Dunn'sShort Sensory Profile (SSP) to assess demographic data and parents'perceptions of their children with regards to DSI.Results Of 264 questionnaire packets distributed, 117 packetswere returned (44.3%). Most children were of Chinese ethnicityand aged 3 to 5 years. Of the 117 children, 49 children ( 41.9%)met the criteria for DSI (definite difference), 33 children (28.2%)were in the probable difference category for DSI, and 35 children(29.9%) were in the category of typical performance. The scores forthe parameters of under-responsive and visual/auditory sensitivitywere the most commonly observed in subjects in the definitedifference category. From all questionnaire packets, a total of18.56% of children in selected kindergartens in North Jakartamet the screening criteria for DSI, while an additional 12.5%were likely to have the disorder.Conclusion Based on parental reports, we find that 18.56% ofchildren from two private kindergartens in North Jakarta hadDSI, while an additional 12.5% are likely to have the disorder.

Comparison of peak expiratory flow measurement by Mini-Wright peak flow meter and electronic spirometer in healthy elementary school children Mardjanis Said; Sudigdo Sastroasmoro; Bambang Supriyatno; Yovita Ananta
Paediatrica Indonesiana Vol 44 No 6 (2004): November 2004
Publisher : Indonesian Pediatric Society

Objective This study aims to compare peak expiratory flow mea-surement by peak flow meter and electronic spirometer in healthyelementary school children.Methods This was a cross-sectional study performed in an el-ementary school near Cipto Mangunkusumo hospital (SDNPegangsaan 01). The study group consisted of healthy childrenaged 6-12 year old. Data regarding identity and history of illnesswas taken in each subject. Routine physical examination was per-formed and recorded. Each subject performed lung function testsby means of electronic spirometer AS-7 as well as by Mini-Wrightpeak flow meter. The subject should perform a minimum of threemaneuvers for each method where only the best result was re-corded. Method comparison test to assess agreement betweentwo methods was employed in this study.Results There were 10 males and 15 females enrolled in this study.None of the subjects currently have any respiratory symptoms andsigns. This study found that the mean peak expiratory flow (PEF) byspirometer was 226.8Â±73.13 L/min while by peak flow meter was223.0Â±45.05. Mean difference between spirometer and peak flowmeter measurements is 6.2 with standard deviation of 60.82. Thesevalues resulted in limits of agreement of -115.44 to +127.84 L/min.Conclusions This study finds disagreement between electronicspirometer and Mini-Wright peak flow meter in measuring peakexpiratory flow, therefore these two devices cannot be usedinterchangeably. Mini-Wright peak flow meter still has a role inhome monitoring, but the physician should interpret the resultscarefully.

Clinical and laboratory features of children with insulin dependent diabetes mellitus of more than two years Jose R. L. Batubara; Agus Firmansyah; Riza Mansyoer; Bambang Tridjaja; Aman B. Pulungan
Paediatrica Indonesiana Vol 41 No 9-10 (2001): September 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi41.5.2001.256-9

The incidence rate of IDDM in our clinic during the period from 1989 to 1998 was 0.028%. There were twentyfour IDDM patients with duration of illness of more than 2 years, with a male to female ratio of 1: 1.5. Most of these patients had no diabetic family history and had good nutritional status. The insulin dosage used by these patients ranged between 0.67 - 0.72 IU/kg/day with a mean of 1.06 IU/kg/day. The average frequency of blood glucose home monitoring was less than ideal. Twenty-two out of the 24 patients were fully controlled metabolically; however, these patients still have polyuria, polydipsia, and polyphagia.

Postgraduate Pediatric Training Programme in the Department of Child Health, Medical School University of Indonesia, Jakarta H.E. Monintja; W.T. Karjomanggolo; R. Sutejo
Paediatrica Indonesiana Vol 18 No 1-2 (1978): January - February 1978
Publisher : Indonesian Pediatric Society

Paediatrics is a major subject in undergraduate as well as postgraduate medical training. Demographic data show that 44% of the population in Indonesia as well as in other developing countries belongs to the paediatric age group. The objective of the training of paeditrician should be relevant to the needs of the society in child health care using the available potentials in the society and with the participation of the society. In this paper the determinant of objective, the objective, the methodology, the evaluation and the feedback system of the postgraduate paediatric training programme in the Department of Child Health, Medical School, University of Indonesia, is briefly described.

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