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INDONESIA
Journal of Medical Biomedical and Applied Sciences
Published by Innovative Journal
ISSN : -     EISSN : -     DOI : -
Core Subject : Health, Science,
Arjuna Subject : -
Articles 112 Documents
Does Planter Pressure Distribution Alter with Weight Reduction in Obese Children? Radwan, Nadia L.; Ibrahim, Marwa M.
Journal of Medical Biomedical and Applied Sciences Vol 5 No 12 (2017)
Publisher : Journal of Medical Biomedical and Applied Sciences

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Abstract

Background: High plantar pressure values in obese children are of great concern due to the risk of inducing pain, discomfort, and foot pathologies, mainly for children’s growing feet. Obese children have been observed to have flat feet compared to those of their non-obese correspondents. Objective: The purpose of this study was to detect whether there were differences in the static and dynamic planter pressure distribution variables after weight reduction in obese children. Methods: Thirty obese prepubescent girls aged from 8 to 11 years were included in the study. The Tekscan foot pressure system was used to measure the static and dynamic plantar pressures before and after nine months of weight reduction program. The peak pressures beneath the forefoot, midfoot and rearfoot were measured for each foot. The weight reduction program consists of a combined dietary and exercise program. Results: The study revealed high significant differences in the peak force, contact area and in plantar pressure in standing. Significant differences were also found in dynamic pressure variables particularly under the mid foot region which was highly significant. Conclusion: It was concluded that decreasing the weight of obese children is an important issue because it will decrease both static and dynamic pressure variables, and in consequence decreasing the risk of obtaining foot problems, stress fractures, or ulcerations caused by effect of their increased weights  on their growing feet.
Integration of Traditional and Western Medicine treatment benefits to lupus nephritis disease: a systematic review and meta-analysis yang, Meng
Journal of Medical Biomedical and Applied Sciences Vol 5 No 12 (2017)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (922.658 KB) | DOI: 10.15520/jmbas.v5i12.81

Abstract

Objective:To systematically evaluate the clinical effect of integrated traditional Chinese medicine and Western Medicine (TCM-WM) and to investigate effective therapy of traditional Chinese medicine (TCM ) for lupus nephritis(LN). Methods A meta-analysis      was performed of all the literatures  germane  to estimate the patients treated with TCM-WM and western medicine(WM ) alone from published randomised controlled trials (RCTs) from 1990 to 2013. Results 12 RCTs were included. The methodological quality was generally low. The complete remission rate(RR =1.68, 95%CI 1.48-1.90, P<0.00001) and the total remission rate(RR =1.19, 95%CI 1.13-1.24, P<0.00001) of TCM-WM were higher than that of WM .The relapse rate(RR =0.3, 95%CI 0.22-0.42, P<0.00001), incidence of adverse reactions (RR =0.46, 95%CI 0.40-0.54, P<0.00001)and mortality rate (RR =0.38, 95%CI 0.23-0.63, P=0.00002)  of  TCM-WM were much lower than WM.  Conclusion  Our results indicate that using improving the blood flow clearing away toxic material, activating blood circulation to dissipate as central TCM-WM therapy were superior to therapy with WM alone. However, its effect on LN requires further careful study due to limited available randomized control trials.
Incursion of Helminthosporium leaf blight disease of wheat in comparatively cool hilly regions of Nepal Bhandari, Deepak
Journal of Medical Biomedical and Applied Sciences Vol 5 No 12 (2017)
Publisher : Journal of Medical Biomedical and Applied Sciences

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Abstract

Helminthosporium Leaf Blight (HLB) caused by Bipolaris sorokiniana (Shoem.) and Pyrenophora tritici repentis (Died.) is the most problematic leaf spotting disease of wheat in warm plain regions of Nepal. Because of increasing temperature, erratic rainfall and changing weather conditions, the disease can also become devastating in vast mid-hill regions having comparatively cool temperature. Various levels of severity and intensity of HLB disease of wheat have been reported from different plain areas of Nepal; however, the confirm status of HLB disease of wheat in mid-hills and hills of Nepal is still lacking. Therefore, a study was carried out to identify the severity and intensity of HLB disease of wheat in five districts of mid-hill during 2012 and 2013 crop season.  Field monitorings were carried out and diseased samples were collected twice at Lalitpur, Bhaktapur, Dhading, Kathmandu and Nuwakot districts during the two crop seasons. The status of wheat crop and associated diseases under field conditions were observed and recorded. About 100 diseased leaf samples were collected from different fields of each site. The samples were than incubated under moist chambers for seven days at room temperature in laboratory of Plant Pathology Division, Lalitpur. After the incubation, the samples were studied under stereoscope microscope for the presence of leaf spotting pathogens. The condition of wheat crop at field was fair to good, and the leaf spotting disease symptoms were very low in most of the visited sites during first monitoring. The growth of the crop was still fair to good; however, considerable symptoms of leaf spotting diseases were observed in penultimate leaf and lower leaves in second monitoring. After heading stage, most of the wheat plants were infected with leaf spotting diseases; nevertheless, only scattered leaf spots were observed in single leaf and the total infected area in each leaf was petite. The intensity of leaf spotting disease was mild in popular wheat variety WK 1204. There was extensive growth of leaf spotting pathogens Bipolaris sorokiniana and Alternaria species on incubated leaf samples. More than 85% leaf samples were infected with devastating pathogen Bipolaris sorokiniana followed by Alternaria spp. and Epicoccum sp. The presence of Pyrenophora tritici repentis was also noticeable. The results indicate that the leaf blight disease of wheat has been increased in areas having moderate temperature, and will be a problem in future for wheat growers of Kathmandu valley and similar mid-hills regions of Nepal.
HIV AIDS-Medico Legal Point of View Wasnik, Dr. Sumedh; Sulakhe, Dr. Vaibhav; Ghodke, Dr. Anita; Vaidya, Dr. Nilam
Journal of Medical Biomedical and Applied Sciences Vol 6 No 1 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (799.72 KB) | DOI: 10.15520/jmbas.v6i1.83

Abstract

Now a day, AIDS is the most burning issue of public health before medical world. Everyone is thinking about its every aspect.  AIDS awareness is increasing day by day among the public, hence the ethical, legal and regulating issues are in focus. In developing country like India, every  effort is made to protect individual rights while safeguarding the public from a fatal communicable virus .There are many unprecedented legal question in public health, education employment, insurance, medical law, family law, civil rights  about HIV AIDS. Presently, there is no legislation particularly integrating all issues concerning HIV & AIDS. Without respect for the human rights, fundamental freedom and the dignity of human beings, there will be no valid treatment for the said disease. Effective prevention, care and support for HIV/AIDS is possible in an environment where human rights are respected and where those infected or affected by HIV/AIDS live a life without stigma and discrimination. The protection of human rights is essential to safeguard human dignity in the context of HIV/AIDS. All possible efforts should be made to train all medical, paramedical and other auxiliary medical health care workers to aware about environment where HIV/AIDS patients are admitted and treated without any fear & scare so that the patients don’t feel guilty and get ready for the treatment.
Clinical and Epidemiological Features of Diaphyseal Femoral Fractures In Douala Leon Jules, Owona Manga; Tsigadigui, Jean Gustave; Chichom-Mefire, Alain; Ibrahima, Farikou; Félicité, Mbock Evelyne; Aurélien, Sosso Maurice
Journal of Medical Biomedical and Applied Sciences Vol 6 No 1 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

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Abstract

The femur, which is the strongest bone in humans, is often put under stressful constrains during the daily life trauma that can lead to consequences such as fractures.
Oral Changes after Radiotherapy in Patients with Head and Neck Cancer Maldonado, Natalia Souto Outeda; Prosdocimi, Fabio C.; Sampaio, Rui Manuel Freire; Junior, Adhmar Sani; Schmidt, Arthur Georg; Roman-Torres, Caio Vinicius G.
Journal of Medical Biomedical and Applied Sciences Vol 6 No 2 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

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Abstract

Cancer of the mouth begins in the oral cavity which includes: lips, jugal mucosa, teeth, gums, the first two-thirds of the tongue, floor of mouth, hard palate and retromolar trigone. Radiation therapy is a method capable of destroying tumor cells, employing a beam of ionizing radiation, seeking to eradicate all tumor cells with the least possible damage to the surrounding healthy cells at the expense of which the regenerated area will be regenerated. The objective of the present literature review was to report the main pathologies related to the performance of radiotherapy in patients with head and neck cancer. We selected articles published in the years from 1978 to 2017. The response of the tissues to radiation depends on several factors, such as the sensitivity of the tumor to radiation, its location and oxygenation, as well as the quality and quantity of radiation, in addition to the total time given. The oral complications of radiotherapy of head and neck neoplasms are common because they are rapidly renewing cells suffering greater action of the radiation agents, and can compromise the quality of life of the patient, besides negatively affecting the course of the cancer treatment until its suspension. Adverse reactions to radiation therapy are classified as acute, which occur during treatment or up to three months after the end, and late, which may manifest several months or years after the end of treatment. Oral mucositis is a clinically important and sometimes dose-limiting complication of cancer therapy. Mucositis lesions can be painful, affect nutrition and quality of life, and have a significant economic impact. Protocols for the treatment of the adverse effects of radiotherapy in the stomatognathic system are the responsibility of the dental surgeon. These include symptomatic relief, systemic medicines, physiotherapy, accumulating and oral lubricants, excellent oral hygiene and diet of certain types of food.  
Comparative Dynamics of The Efficiency of Antithrombotic Prophylaxis Before Delivery In Pregnant Women With Different Forms of Antiphospholipid Synrome Gurbanova, J.F.; Guliyeva, M.A.
Journal of Medical Biomedical and Applied Sciences Vol 6 No 3 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (317.152 KB) | DOI: 10.15520/jmbas.v6i3.93

Abstract

Objectives: The aim of this study was the assessment of effectiveness of antithrombotic prophylaxis in pregnant women with different form of APS. Methods of study: For the assesment of condition and effectiveness of treatment of pregnants, the investigations were carried out in 92 women. In various periods of pregnancy were determined non-active thrombin-antithrombin III (TAT) complex, protrombin fragments (F1+2), D-dimer et c. Results and conclusions: Long-term antithrombotic prophylaxis with low-molecular heparins allows to decrease the level of thrombophilic markers in pregnant women with different forms of APS. Monotherapy with low-molecular heparins in women allows to normalize the level of thrombofilic markers and effectively prevents thrombosis.
“A POTENTIAL NONINVASIVE BIOMARKER OF NONALCOHOLIC STEATOHEPATITIS” Oliveira, Yanaihara Pinchemel; Cotrim, Helma; Daltro, Carla; Alves, Erivaldo; Barros, Raffaelle
Journal of Medical Biomedical and Applied Sciences Vol 6 No 3 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (785.088 KB) | DOI: 10.15520/jmbas.v6i3.95

Abstract

Background/Aim: Liver biopsy remains the gold standard for characterizing the histology of nonalcoholic fatty liver disease, yet this procedure is invasive. Oxidative stress plays an important role in the pathogenesis of steatohepatitis and erythrocytesare known to exert pro-oxidant activity. We hypothesized that erythrocytes damaged by oxidative stress could represent potential biomarkers capable of distinguishing steatosis from steatohepatitis. Methods: Our sample included 37 obese patients who underwent bariatric surgery and liver biopsy. Patients were classified according to histological diagnosis with respect to steatosis or steatohepatitis. Oxidative stress measurements were performed by chemiluminescence. Erythrocytes obtained from the whole blood of patients were stained to evaluate cell morphology by optical microscopy. Results: Higher levels of oxidative stress were seen in obese patients with steatohepatitis in comparison to those with steatosis (Cohens d=4.1). Erythrocytes damaged by oxidative stress were found in 81.2% of patients with steatosis and in 95.2% of the steatohepatitis cases (Phi= 0.22). These results were confirmed in an in vitro model. Oxidative stress levels were found to be elevatedin 60.6% of the cases in which modified erythrocytes were also present. Conclusions: The results indicated that altered erythrocytes may represent a novel noninvasive biomarker capable of distinguishing steatosis from steatohepatitis.
Renal Perinephric Abscess Complicated with Psoas Muscle Abscess D, Kochiashvili; T, Didbarize; V, Kvakhajelidze; G, Kochiashvili
Journal of Medical Biomedical and Applied Sciences Vol 6 No 3 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (208.562 KB) | DOI: 10.15520/jmbas.v6i3.99

Abstract

Perinephric abscess is an uncommon complication of urinary tract infections. The incidence ranges from 1-10 cases for every 10000 hospital admissions. Men and women are affected with equal frequency. Escherichia coli, Proteus speacies and Staphylococcus aureus are the unusual etiologic organisms. There were very few reports about urinary tract infections such as renal perinephric abscess complicated with psoas muscle abscess.Renal and perirenal abscess can complicate aurologic infection (usually due to gram-negative enteric bacilli or a polymicrobial infection). This clinical case of a 24 year old men with predisposing condition for secondary psoas muscle abscess (6 year history of the right non functional kidney), is interesting because of unusual etiologic organisms for psoas muscle abscess Proteus mirabilis, which is highly flagellate, have stone formation ability which is very difficult to clear with only antibiotics, has predilection for the kidney and are difficult to eradicate.
Correlation Among Inhibin A And B, Anti-M ¨Ullerian Hormone, Follicle-Stimulating Hormone, Luteinizing Hormone, And Estradiol Hormones In Infertile Women Aytan Ali, Abdullayeva; Fazil Kurbanova, Jamila
Journal of Medical Biomedical and Applied Sciences Vol 6 No 3 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.001 KB) | DOI: 10.15520/jmbas.v6i3.100

Abstract

Objective: The main purpose of this study was to assess ovarian reserve in infertile women and whether hormonal status depends on anti-M¨ullerian hormone level.Study Design: This retrospective study evaluated and compared inhibins A and B, follicle-stimulating hormone, luteinizing hormone, and estradiol concentrations in 67 infertile women with anti-M ¨ullerian hormone level <600 ng/L and in 39 infertile women with anti-M¨ullerian hormone level >600 ng/L. Data were analyzed using SPSS version 20 (IBM, Armonk, NY, USA) and reported as mean±standard deviation or number and percentage. The data in the study groups were nonparametric.Results: The mean concentrations of inhibin A and B and estradiol levels were lower (p<0.05) in infertile women with low anti-M¨ullerian hormone level. Serum inhibin A level (p<0.01) positively correlated with inhibin B level in women with anti-M¨ullerian hormone level <600 mg/mL. In women with anti-M¨ullerian hormone level >600 mg/mL, negative correlations were found between inhibin A and B levels (r=0.494, R2=0.13, p<0.01) and between anti-M¨ullerian hormone and inhibin B levels (r=-0.426, R2=0.149, p<0.01), but a positive correlation was demonstrated between inhibin A and anti-M¨ullerian hormone levels (r=0.545, R2=0.096, p<0.01). The analyses of correlations between follicle-stimulating hormone and estradiol showed a major coefficient of correlation (r=0.545, R2=0.287, p<0.05). There was no correlation between age and anti-M¨ullerian hormone.Conclusion: Differences in correlation between inhibin A and B levels in groups with different anti-M ¨ullerian hormone levels demonstrate their importance in the evaluation of ovarian reserve in infertile women. Hence, we conclude that ovarian reserve assessment in infertile women should include not only the anti-M ¨ullerian hormone level bwut also the inhibin A and B levels.

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