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Rachmat Kosman
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As-syifaa Jurnal Farmasi
Published by Universitas Muslim Indonesia
ISSN : 20854714     EISSN : 25029444     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
As-Syifaa Jurnal Farmasi receives manuscripts in Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmacology and Toxicology, Pharmaceutical Microbiology and Biotechnology, Herbal Medicines, Pharmaceutics, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 397 Documents
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ANALISIS KADAR FLAVONOID DAN FENOLIK TOTAL FRAKSI ETIL ASETAT DAUN KETEPENG CINA (Senna alata (L.) Roxb) DENGAN METODE SPEKTROFOTOMETRI UV-VISIBLE Rahmawati Rahmawati; A. Muflihunna; A. Trihadi Kusuma
As-Syifaa Jurnal Farmasi Vol 7, No 1 (2015): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (107.67 KB) | DOI: 10.33096/jifa.v7i1.16

Abstract

Analysis of flavonoid and phenolic content of ethyl acetate fraction have done in chinese ketepeng leaves (Senna alata (L.) Roxb) using UV-Visible spectrophotometric method. This research aimed to analyzed of flavonoids and phenolic content of ethyl acetate fraction of chinese ketepeng leaves. Chinese ketepeng leaves were extracted using ethanol 96%, and then were partitioned using a liquid-liquid partition method of ethyl acetate to obtain ethyl acetate fraction. Flavonoid and phenolic content determined using UV-VIS spectrophotometric at 415 nm wavelength for flavonoid and 730 nm for phenolic. This research results showed that the flavonoid content of ethyl acetate fraction of chinese ketepeng leaves is 2,665 mgRE/g and phenolic content of ethyl acetate fraction of chinese ketepeng leaves is 3,729 mgRE/g.
UJI EFEK DIURETIK INFUS BIJI JAGUNG (Zea Mays L), RAMBUT JAGUNG DAN KOMBINASI ANTARA KEDUANYA PADA KELINCI JANTAN (Oryctolagus Cuniculus) BERDASARKAN PARAMETER FREKUENSI URINASI DAN VOLUME URIN Hendra Herman; Rizqi Nur Azizah; Chikita Inaku
As-Syifaa Jurnal Farmasi Vol 4, No 1 (2012): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (92.236 KB) | DOI: 10.33096/jifa.v4i1.144

Abstract

Has been done research Diuretic effect test of seed corn infusem, hair Corn infuse and combination of both in order to determining diuretic effect with frequency urination and volume urine  parameters. This research use trial animals as many as 15 male rabbits, divided into 5 groups and each group consisted of three tails, group I is control that given colloidal solution of Na.CMC 1 %,  group II infuse corn (Zea mays L) 23 33 mg group III has Qvien seed corn infuse (Zee mays L ) 466,664 gr,  group IV has Given combination of hair and sedd corn infuse and group V is comparator that given suspension of furosemid Treatment done orally with a dose of 20 / 2,5 kg for further observation and measurement frequency done diuretic and urine  volume intervals of 1 hour for  5 hours after treatment The result showed that infuse of seed corn, hair corn and combination of both can increase the frequency of urination, and just infuse of seed corn and hair corn increase the volume win of rabbits This is supported by statistical analysis methods CRD (Completely Randomized Design) For the frequency of urination infuse of seed corn, hair corn, and combination of both did not significantly different with furecemid while for the volume urine hair corn infuse and seed corn infuse are significantly different  with Na CMC and not significantly different with furosemidKey words: Diuretic, seed and hair corn Infuse
PENATALAKSANAAN HIPERPLASIA GINGIVA DISEBABKAN OLEH PENGGUNAAN AMLODIPINE : Sebuah Laporan Kasus Arni Irawaty Djais; Lilies Anggarwati Astuti
As-Syifaa Jurnal Farmasi Vol 6, No 2 (2014): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (210.108 KB) | DOI: 10.33096/jifa.v6i2.42

Abstract

Introduction: gingival hyperplasia is a result of administration from some anticonvulsant drugs, immunosuppressants, and calcium channel blockers that well known can cause problems when speaking, mastication, tooth eruption, and aesthetic. Calcium channel blockers are a class of drugs developed for the care of cardiovascular conditions. Some of these drugs can cause gingival enlargement.  Case: A 55-year-old female patient came to Periodontal Department of Hasanuddin University Dental Hospital,Makassar. Patients present with a less comfortable and did not feel confident with the condition of the front of the upper jaw gums since three months ago. These symptoms begin to be felt since taking drugs for hypertension disease with amlodipine with 10 mg 1 time a day. The patient began to feel a change in the form of excessive enlargement of the gums almost the entire upper jaw teeth. Management of Case: Disinfection area of operation, anesthesia with lidocaine 2% of nor epinephrine, marking the pocket using the pocket marker basis, incision using Krickland knife, removal of gingiva using papilla Orban knife and performed by scaling and root planing, periodontal pack was used. Conclusion: Patients who took the drug amlodipine as calcium channel blocker classification in the long-term directly effects the growth of excess gingival tissue, causing gingival enlargement. Keyword: Hyperplasia Gingiva, Amlodipine
AKTIVITAS ANTIFUNGI TEMU PUTIH (Curcuma zedoaria) TERHADAP Trichophyton mentagrophytes Nuryanti, Siska
Jurnal Ilmiah As-Syifaa Vol 8, No 2 (2016): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (123.484 KB) | DOI: 10.33096/jifa.v8i2.214

Abstract

Curcuma zedoaria has long been known to be used in treatment of dermatophytosis; a skin disease caused by dermatophytes fungi such as Trichophyton mentagrophytes.The fungi infects hairs, skins, and nails that contain keratin. The study was conducted in order to measure the effect of ethanol extract of curcuma zedoaria in inhibiting Trichophyton mentagrohytes colonies. Results showed that the curcuma zedoaria ekstract inhibited Trichophyton mentagrophytes. The research was continued by Minimum Inhibitory Concentration (MIC) test by liquid dilution method in Sabaroud Dekstrosa Broth. Ethanol extract curcuma zedoaria did not indicate the value of the MIC test  because due to the color and viscosity of samples which interfere with the observations. As for the positive control shows a clear color, that  indicating the presence of inhibitory Trichophyton mentagrophytes by ketokonazol. For the value of the Minimum Fungicidal Concentration (MFC) to Trichophyton mentagrophytes are present in a concentration of 50%.
FORMULASI SALEP EKSTRAK METANOL DAUN SRIKAYA (Annona squamosa L) DENGAN BERBAGAI VARIASI BASIS Muflihunna, A.; Lating, Hediyanti
Jurnal Ilmiah As-Syifaa Vol 5, No 1 (2013): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (149.383 KB) | DOI: 10.33096/jifa.v5i1.71

Abstract

This research methanol extract srikaya leaf performed to formulate ointments in bases variation that were hydrocarbon base, absorption base, water-soluble and emultion base. The aim was to determine which one the most stable base contain the methanol extract srikaya leaf. Stability evaluation maked in two condition were before and after stress condition at 5oC – 35oC for 10 cycles, by which the parameters were organoleptic observation, viscosity measurement, and yield value determination. Result of organoleptic showed that there was not alteration in color, smell, and consistency of those four bases, before and after stress conditioned. Statistyc data analyse of viscosity measurement showed that formula in absorption base was the stable one due to no alteration before and after accelerated condition. Yield value showed that there was thixotrophy plastic flowing exhibited by rheogram. And of those four formula ointment types of methanol extract srikaya leaf (Annona squamosa L) that have been made in, absorption base was the most stability optimum base.Key words : Srikaya Leaf, Formulation, Ointments
ISOLASI DAN IDENTIFIKASI GOLONGAN KOMPONEN KIMIA AKTIF ANTIBAKTERI EKSTRAK N-BUTANOL SAWO MANILA (Achras zapota LINN.) ASAL KOTA PALOPO Rusli, Rusli; Prayitno, Dedy
Jurnal Ilmiah As-Syifaa Vol 9, No 2 (2017): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (102.441 KB) | DOI: 10.33096/jifa.v9i2.310

Abstract

Sawo manila is one of the Zapotaceae family plant which have been investigated on n-butanol extract generate active spot as an antibacterial, therefore isolation and investigation of  which is necessary. The aim of the investigation was to identify the chemical group of antibacterial  active chemically. The methanol extract obtained by maceration method was 50 gram, continued by partition with diethyl eter obtained 17,3 gram dried extract, the residue ofiz then partition with n-butanol obtained 3,7 gram dried extract the extract of which isolated by conventional colomn cromotography method obtained 7 fractions. The second fraction on Bioautografi-TLC given antibacterial activity. Then the fraction  re-isollated  by preparative-TLC gained the second (2nd) band of which crystalzed by two dimention of TLC and multi eluen system. The single spot had positive reaction on the spot visualizer was alkaloid group with the maximum wavelength on 295,5 nm and the infra red spectra interpretation shown that amin group (NH) on wave value 1247 cm-1, 2361 cm-1, and 1294 cm-1 strengthen by secondary amin functional group (-NH-), within wave value 3447 cm-1 and 1294,26 cm-1,  aromatic CH group and the aromatic amin 1451 cm-1, unconjugated alkene group on 1652.32 cm -1 strengthen by alkene group on 2922,37 cm-1. 
PRODUKSI DAN ANALISIS AGAROSA DARI RUMPUT LAUT JENIS Gracilaria sp. ASAL KABUPETEN TAKALAR Abidin, Zainal; AP, Pirman; Kosman, Rachmat
Jurnal Ilmiah As-Syifaa Vol 2, No 1 (2010): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v2i1.103

Abstract

Has been done attempt production and analisis of agarose from seaweed Gracilaria sp. of Takalar Regency, with aim to produce agarose and analysis physicochemical properties such as viscosity, yield value, and characterized fungsional groups of agarose with Spectra Infra Red (IR). The result attempt showed that 10 gram of seaweed Gracilaria sp. yield 1,434 gram agarose, and if agarose in colloid solution 1% at 80oC had the viscosity 15,2 cP and the yield value 0,039 dyne cm-, while IR spectra obtained the hydroxyl group (OH) with hydrogen bonding in the region 3455.10 cm-1, the hydrocarbon group (C-H) in the region 1455.77 cm-1 and the  ethers group (C-O) in the region 1077.32 cm-1. Which the result could be compared with the standart agarose.  Key words :  Agarose, Glacilaria Sp., Takalar
UJI AKTIVITAS EKSTRAK BIJI SELASIH (Ocimum basilicum L.) DENGAN BEBERAPA PELARUT SEBAGAI ANTIPIRETIK PADA MENCIT (Mus musculus) Rahimah, Sitti; hendrarti, Wahyu; Ramlah, Sitti
Jurnal Ilmiah As-Syifaa Vol 7, No 2 (2015): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (93.534 KB) | DOI: 10.33096/jifa.v7i2.7

Abstract

Seeds basil (Ocimum basilicum L.) has been known to the publicand is widely used to treat a variety of diseases. One of its benefits as lowering fever but have not been proven scientifically. This study was to determine whether there is an antipyretic effecte basil seeds (Ocimum basilicum L.) and to determine the effectiveness of extracts of basil seeds by using some of the solvent is n-hexane, ethyl acetate and ethanol compared with paracetamol in mice (Mus musculus). This study was an experimental study using RAL. Experimental animals used were 15 mice, stages of research giving treatment af mice in each group who had fasted for 12 hours, measured rectal temperature (initial temperature), then injected with 1 ml peptone/tail subcutaneously. The data obtained were analyzed ANOVA followed BNJ test. Test antipyretic extract basil seeds (Ocimum basilicum) with some solvent, most effectively used as a solvent in the basil seeds that solvent ethyl acetate compared with solvent n-hexane and ethanol. The results oft his study showed that the extract of basil seeds antipyretic effect.
FORMULASI EKSTRAK DIETIL ETER RIMPANG LEMPUYANG WANGI (ZINGIBER AROMATICUM VAL.) SEBAGAI KRIM MASKER Muflihunna, A.
Jurnal Ilmiah As-Syifaa Vol 3, No 2 (2011): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v3i2.135

Abstract

An investigation has been done about formulation of Dietil Eter Ekstract of Lempuyang Wangi Rhizome (Zingiber Aromaticum Val.) as A Cream Mask by using variation concentration of nonionic emulgator (polysorbat 20 and sorbitan monostearic) that were  formula A (concentration 3%), formula B (concentration 2%), and formula C (concentration 1%). There aim of investigation was to determine the Formulation of Dietil Eter Ekstract of Lempuyang Wangi Rhizome (Zingiber Aromaticum Val.) as A Cream Mask which has an optimum stability.                Stability evaluation has done by observation of organoleptic, creaming volume, dispersed globule, viscosity and yield value, and emulsion type determination before and after stress condition at 50C and 350C for 10 cycles.                Observation’s result shown that there wasn’t change before and after stress condition of orgenoleptic, creaming volume, emulsion type, rheology type before and after stress condition. Statistic analyse result of parameter viscosity and yield value by means of random black design shown that formula B (concentration 2%) obtained apparent indifferent in dispersed globule, viscosity and yield value between before and after stress condition. The conclusion that cream mask has the most optimal  stability is that by formula B (concentration 2%).Key Words : Formulation, Lempuyang Wangi Rhizome, Cream Mask
PENGARUH PENUNDAAN WAKTU TERHADAP HASIL URINALISIS SEDIMEN URIN Naid, Tadjuddin; Mangerangi, Fitriani; Almahdaly, Hanifah
Jurnal Ilmiah As-Syifaa Vol 6, No 2 (2014): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (156.996 KB) | DOI: 10.33096/jifa.v6i2.51

Abstract

A research about the effect of time delays on the result of urinalysis urine sediment. This research is aimed to determine the presence or absence effect of delay on the result of urine sediment eximination. This research used cross sectional study. Total amount sample was 37 samples and using urine at the time. A microscopic examination of a sample ( urine sediment) by the method of Shih-Yung. The research result showed that the average number of leukocytes in immediate examination, 2 hour, amd 3 hour are 1,29/µl, 1.05/µl, 0,89/ µl respective, the average numberof erythroctes immediate examination,2 hour, and 3 hour are  0,70/ µl, 0.59/ µl, 0,48/µl, respective, the average number of epitheliel cell examination immediate, 2 hour, and 3 hour are 9,70/LPB, 8,51/LPB, 7,54/LPB respective. By One Way Anova statistical Test, test value P>0,05 with a value of F count < F table. Based one data the result of study then it can be conclusion that are no signifikan effect of time delay urine sediment examination immediate, 2 hours and 3 hours at room temperature.Key words: Time, Urinalisis, Urin.

Page 22 of 40 | Total Record : 397

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