cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Rachmat Kosman
Contact Email
jurnal.farmasi@umi.ac.id
Phone
+6281342695698
Journal Mail Official
rachmatkosman@umi.ac.id
Editorial Address
Fakultas Farmasi UMI, Kampus II, Universitas Muslim Indonesia, Jl. Urip Sumohardjo Km.5, Makassar
Location
Kota makassar,
Sulawesi selatan
INDONESIA
As-syifaa Jurnal Farmasi
Published by Universitas Muslim Indonesia
ISSN : 20854714     EISSN : 25029444     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
As-Syifaa Jurnal Farmasi receives manuscripts in Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmacology and Toxicology, Pharmaceutical Microbiology and Biotechnology, Herbal Medicines, Pharmaceutics, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 397 Documents
 22   23   24   25   26 
VARIASI EKSTRAK ETANOL BIJI ALPUKAT (Persea americana Mill.) PADA GRANUL EFFERVECSENT SEBAGAI ANTIDIABETES Herwin Herwin; Hendra Herman
As-Syifaa Jurnal Farmasi Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (410.117 KB) | DOI: 10.33096/jifa.v11i1.512

Abstract

This study aims to product the preparation effevecsent granule  using variation of ethanol extract avocado seed (Persea americana Mill.) as antidiabetic using granulation method. This study was conducted using two formulas using variation of ethanol extract avocado seed (Persea americana Mill.) 1% and 10%, PVP K30 4%, Sodium cyclamate 0.1%, citric acid 0.2965 gram, tartric acid 0.5931 gram and sodium bicarbonate 1.0083 gram. The test results of evaluation preparation effevecsent granule  using variation of ethanol extract avocado seed (Persea americana Mill.) showing that formulas 2 (two) is the best the result farmaceutic evaluation obtained with value Densitas Bulk = 2.82, Incompressible Density = 0.353, Carr’s Indeks = 17.12, Silent Angle = 19.790, Flow Time = 0.7, Time of Stopping Foam = 1.15. The test results of antidiabetic at in vivo formulas 2 (two) preparation effevecsent granule of ethanol extract avocado seed (Persea americana Mill.) using male mice (Mus musculus) with weight 176.5 mg, Initial Glucose Level = 87.5, Initial Glucose Induction = 249.5 obtained time of giving theraphy of formula at first day = 248.5, second day = 133, five day = 109 and seven day = 75.5, so preparation effevecsent granule of ethanol extract avocado seed (Persea americana Mill.) effective as antidiabetic.
PENGARUH SENYAWA KOFAKTOR DAN STABILITAS TERHADAP AKTIVITAS ENZIM β-1,3-GLUKANASE DARI ISOLAT BAKTERI TERMOFIL Bacillus licheniformis HSA3-1a Seniwati Dali; Hasnah Natsir; Gusti Gusti
As-Syifaa Jurnal Farmasi Vol 4, No 2 (2012): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (197.432 KB) | DOI: 10.33096/jifa.v4i2.85

Abstract

Study on the effect of compound cofactor and stability to enzyme activity of β-1 ,3-glucanase has been done. This study used bacterial isolates B. licheniformis HSA3-1a isolated from a hot spring Sulili Pinrang as a source of the enzyme β-1 ,3-glucanase. Isolation of enzyme made after bacterial are activated and cultured in fermentation medium, pH 7,0 and temperature of 50 0C for 4 days. The resulting enzyme performed activity assay. Activity of enzyme assays performed by adding the compound cofactor MgCl2, CaCl2, CuCl2, CoCl2, and ZnCl2 at different concentrations (0.25, 0.5, and 1.0) mM. To determine the stability of the enzyme made by varying the incubation time (0, 30, 60, 90, 120 and 180) minutes. The result showed that the cofactors of compounds that can serve as an activator for the enzyme β-1 ,3-glucanase from B. licheniformis HSA3-1a is MgCl2 and CaCl2 at a concentration of 0:25 mM, 0.5 mM and 1.0 mM. Compound cofactor of CaCl2 1 mM is stabilizier of enzyme β-1,3-glukanase because the relative activity of the enzyme remaining 86% of the treatment time for 180 minutes prainkubasi.Key Word : β-1 ,3-glucanase, Bacillus  licheniformis HSA3-1a, cofactor, enzyme activity, stability
PERBEDAAN BERKUMUR LARUTAN EKSTRAK SIWAK (Salvadora persica) TERHADAP SEKRESI SALIVA RONGGA MULUT LANJUT USIA DENGAN HIPERTENSI (HT), DIABETES MELITUS (DM) DAN TIDAK MEMILIKI PENYAKIT SISTEMIK DI PANTI SOSIAL TRESNA WERDHA GAU MABAJI GOWA TAHUN 2017 Syamsiah Syam; Risnayanti Anas; Andi Nelva Yunita
As-Syifaa Jurnal Farmasi Vol 10, No 1 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (91.735 KB) | DOI: 10.33096/jifa.v10i1.366

Abstract

Background of Study: Saliva is a complex oral fluid that has an important role associated with biological processes in the oral cavity. Age changes are known to have an effect on decreasing saliva production. Likewise with systemic diseases such as hypertension and diabetes mellitus. Chemical prevention of acid imbalance in the saliva is conducted by rinsing using a siwak extract solution. Chemical content in siwak extract can increase the secretion in the saliva in the oral cavity because it has a bactericidal effect that will prevent acid production from oral bacteria. Objective of Study: To determine the difference of rinsing by using siwal extract solution on salivary secretion of the oral cavity of elderly people who have hypertension, diabetes mellitus, and do not have systemic diseases. Method: This study is pre-experiment with one group pretest and post-test design. The sample of the study was elderly people in a social housing. Also, the research used paired t-test. Result: This study shows the average change in hypertension 1.185 mL/5minute with probability value 0.000, diabates mellitus 1,358mL/5minute with probability value 0.000, does not have systemic disease 1.057 mL/5minute with probability value 0,000 <0,05 meaning there is difference. Conclusion: The difference of mouth washing of 25% extract of siwak solution to elderly salivary secretion in hypertension, diabetes mellitus and did not have systemic disease in social house of tresna werdha gau mabaji gowa.
ANALISIS KADAR KALSIUM (Ca) DAN MAGNESIUM (Mg) PADA KACANG METE (Anacardium occidentale.L) SECARA SPEKTROFOTOMETRI SERAPAN ATOM Rais Razak
As-Syifaa Jurnal Farmasi Vol 2, No 2 (2010): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v2i2.117

Abstract

Analysis of Calsium (Ca) and magnesium (Mg) in the mete nut (Anacardium occidentale L.) by Atomic Absorption spectrophotometry. This research intended to determine rates  of calsium (Ca) and magnesium (Mg) in the mete nut (Anacardium occidentale L.) by means of Atomic Absorption Spectrofotometry. The research enwrap qualitative analysis. Before to be analised, first to do destruction mete nut (Anacardium occidentale L.) later on dissolved in HNO3 and HCl. Qualitative analysis used  specific reactant and quantitative analysis used atomic absortion spectrophotometry at wave length of 422,7 nm and 285,21 nm for calsium and magnesium respectively. The result of the research indicated that average rates of calsium in the mete nut (Anacardium occidentale L.) is 1055,83 mg/100 g of the sample. Average rates of  magnesium in the mete nut (Anacardium occidentale L.) is 58 mg/100 g of the sample.Key Words : Calsium (Ca) and magnesium (Mg) and Anacardium occidentale L
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BUAH BELIMBING WULUH (Averrhoa bilimbi L.) ASAL KOTA WATAMPONE St. Maryam; Saidah Juniasti; Rachmat Kosman
As-Syifaa Jurnal Farmasi Vol 7, No 1 (2015): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (49.823 KB) | DOI: 10.33096/jifa.v7i1.21

Abstract

It has been conducted the research on Assay of Antibacterial Activity of Ethanolic Extract of Wuluh Starfruit (Averrhoa bilimbi L.) The aim of this research is to determine the antibacterial activity. The initial screening assay conducted on several bacteria including Escheria coli, Pseudomonas aeruginosa, Salmonella typhi, Bacillus subtilis, Staphylococcus aureus, Streptococcus mutans, Vibrio cholerae, Shigella dysenteriae. Then, assay on the Minimum Inhibition Concentration (MIC) was carried out with some variations of concentration: 0,05%; 0,1%; 0,2%; 0,4%; 0,8%; and 1,6%. Test result of MIC was then followed by MKC test (Minimum Kill Concentration) using NA medium. The results showed that on concentration 0,4%; 0,8%; and 1,6% inhibit the growth of bacteria tested. Antibacterial activity of ethanolic extract of wuluh starfruit (Averrhoa bilimbi L.) was conducted by using the diffusion agat method. The result showed that the lowest concentration 0,4% ethanolic extract of wuluh starfruit (Averrhoa bilimbi L.) inhibit the growth of bacteria Shigella dysenteriae, Salmonella typhi, Pseudomonas aeruginosa, Vibrio cholerae, Escherichia coli and Staphylococcus aureus.
PENGARUH WAKTU PENYIMPANAN TERHADAP JUMLAH ERITROSIT DARAH DONOR Tadjuddin Naid; Dzikra Arwie; Fitriani Mangerangi
As-Syifaa Jurnal Farmasi Vol 4, No 1 (2012): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.789 KB) | DOI: 10.33096/jifa.v4i1.149

Abstract

A research about the effect of blood storage time to the number of erythrocyte cell count in blood donors has been done at Transfusion Blood laboratory Unit and of laboratoriun Health Of Job Society. This research is aimed to determine the effect of blood storage time to the number of erythrocyte cell count in blood donors which placed at 4o C. This study used experiment laboratory method, with total samples are 5 bags of blood. The result of the research about eritrocyte cell count decresed every week, 4,72% (man) and 5,45% (woman) at the first week, 8,83% (man) and 10,9% (woman) at the second week, 14,17% (man) and 15,53% (woman) at the third week, 21,77% (man) and 25,34% (woman) at the fourth week and 30,39% (man) and 32,7% (woman) at the fifth week.Keywords : storage time, caffeine, erythrocyte, blood donor
AKTIVITAS ANTIBAKTERI FRAKSI-FRAKSI DAUN Colocacia esculenta L. TERHADAP Salmonella thypi Dan Staphylococcus aureus SECARA BIOAUTOGRAPHY-TLC Baits, Muzakkir; Herwin, Herwin; Ririn, Ririn
Jurnal Ilmiah As-Syifaa Vol 8, No 2 (2016): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (45.568 KB) | DOI: 10.33096/jifa.v8i2.224

Abstract

Antibacterial activity test has been done on Colocacia esculenta L leaves fractions. The aim of the research was to determine the antibacterial activity of Colocacia esculenta L leaves fractions delivered from Pare-Pare District of South Sulawesi on Salmonella thypii and Staphyllococcus aureus by means of vacuum liquid chromatography and Bioautographic-TLC. Results of fractionations of the ethanol extract by the former method using eluent of 100 mL n-hexane, n-hexane:ethyl acetate (10:1; 1:1), 100 mL ethyl acetate, ethyl acetate:methanol (10:1; 1:1) and 100 mL methanol were obtained 7 fractions. Bioautographic-TLC assay then carried out on the obtained fractions they were fraction 3,4,5,6 and 7 respectively and obtained Rf value 0.80 was possessed antibacterial activity on both tested bacteria.
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN DAN AMPAS TEH HIJAU (Camellia sinensis L. ) TERHADAP BAKTERI PENYEBAB JERAWAT (Propionibacterium acne DAN Staphylococcus epidermidis ) SECARA DIFUSI AGAR Herwin Herwin; Zulhisda Premeita Sari; Siska Nuryanti
As-Syifaa Jurnal Farmasi Vol 10, No 2 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (325.036 KB) | DOI: 10.33096/jifa.v10i2.448

Abstract

Acne is one skin problem commonly known as acne vulgaris, that is a state where the skin pores are clogged. Some of the bakteria causing the growth on acne are Propianibacterium acne and Staphylococcus epidermidis . Green tea (Camellia sinensis L.) is one of the plants that can be useful as antibacterial. This study aimed to obtained the antibacterial activity of ethanol extract leaves and sregs of green tea which has the  potential  to inhibit the growth of acne causing bacteria by the agar diffusion method. The simplisia of green tea leaves and dregs are macerated with ethanol 96% and obtained the weight of ethanol extract of green tea leaves 34.6 grams. In determination of Minimum Inhibitory Concentration (MIC) ethanol extract of the leaves and the dregs, the MIC value obtained is the same as the two test bacteria on the concentration of 0.1%; whereas, KBM value is on the concentration of 0.4%. The result of the antibacterial activity of ethanol extract of green tea leaves at the largest concentration of 8% has an inhibitory zone diameter of 18.11 mm to Propianibacterium acne and 18.05 mm to Staphylococcus epidermidis. For the antibacterial activity test of ethanol extract the green tea dregs at the largest concentration of 8% has the largest average inhibitory zone diameter of 17.45 mm against Propinibacterium acne and 15.68 mm against Staphylococcus epidermidis.
PRODUKSI BIOETANOL DARI BIJI BUAH NANGKA (Artocarpus heterophyllus) MELALUI PROSES HIDROLISIS ASAM SULFAT DAN FERMENTASI Naid, Tadjuddin; Baits, Muzakkir; Triana, Yenni
Jurnal Ilmiah As-Syifaa Vol 4, No 2 (2012): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (41.116 KB) | DOI: 10.33096/jifa.v4i2.76

Abstract

Fermentation  from jackfruit seeds (Artocarpus heterophyllus) through the Process Using Acid Hydrolysis. Bioethanol is ethanol fermentation process biomass results with the help of microorganisms. Raw materials for bioethanol is sugary materials, starchy and fibrous. This study tries  to make bioethanol from jackfruit seeds (Artocarpus heterophyllus) which is a starchy material. during these jackfruit seeds into consumption only partly public and partly not used. The purpose of this study was to determine the optimum concentration of H2SO4on the hydrolysis process and determine the optimum fermentation time in the fermentation process. The process of making ethanol in two steps, namely acid hydrolysis and fermentation. Cassava peel hydrolyzed by using a solution of H2SO4 in a variety of variable concentrations (0.1, 0.5 and 1 M) at a temperature of 100oC for 1 hour. Then a solution of the hydrolysis fermented with various variables days (1, 2, 3, 4, 5, 6 and 7 days). The result showed that the optimum concentration of H2SO4 solution for the hydrolysis reaction is 1 M at a temperature of 100oC for 1 hour and the optimum fermentation time in the fermentation process is on day 4 where the produced ethanol at 13,19% v/v. Key words : Fermentation, Artocarpus heterophyllus, Hydrolysis
IDENTIFIKASI DNA LEPTOSPIRA SP PADA SAMPEL AIR DAN TANAH DI KOTA MAKASSAR Mursalim, Muhammad Fadhlullah; Hatta, Mochammad
Jurnal Ilmiah As-Syifaa Vol 10, No 1 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (292.731 KB) | DOI: 10.33096/jifa.v10i1.324

Abstract

Leptospirosis is a zoonotic disease that can be found all over the world, caused by a pathogenic leptospira genus. This study aims to identify the presence of Leptospira bacterial DNA in water and soil at several locations in Makassar. This research was conducted in microbiology laboratory Faculty of Medicine Hasanuddin University. A total of 16 samples were taken consisting of water and soil samples taken from four locations in Makassar City namely eggplant market, slums, TPA (final landfill) tamangappa and slaughterhouse (RPH). Samples were then tested using the nested RT-PCR method . The results of this study showed that from 16 samples tested showed one sample with positive to the presence of Leptospira sp bacteria obtained from the soil found in slums located in makassar.

Page 24 of 40 | Total Record : 397

 22   23   24   25   26 

Filter by Year

2009 2025


Reset
Filter By Issues
All Issue Vol 17, No 1 (2025): AS-SYIFAA JURNAL FARMASI Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI Vol 16, No 1 (2024): AS-SYIFAA JURNAL FARMASI Vol 15, No 2 (2023): AS-SYIFAA JURNAL FARMASI Vol 15, No 1 (2023): AS-SYIFAA JURNAL FARMASI Vol 14, No 2 (2022): AS-SYIFAA JURNAL FARMASI Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI Vol 13, No 2 (2021): AS-SYIFAA JURNAL FARMASI Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI Vol 12, No 1 (2020): AS-SYIFAA JURNAL FARMASI Vol 11, No 2 (2019): AS-SYIFAA Jurnal Farmasi Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi Vol 10, No 2 (2018): AS-SYIFAA Jurnal Farmasi Vol 10, No 1 (2018): AS-SYIFAA Jurnal Farmasi Vol 9, No 2 (2017): AS-SYIFAA Jurnal Farmasi Vol 9, No 1 (2017): AS-SYIFAA Jurnal Farmasi Vol 8, No 2 (2016): AS-SYIFAA Jurnal Farmasi Vol 8, No 1 (2016): AS-SYIFAA Jurnal Farmasi Vol 7, No 2 (2015): AS-SYIFAA Jurnal Farmasi Vol 7, No 1 (2015): AS-SYIFAA Jurnal Farmasi Vol 6, No 2 (2014): AS-SYIFAA Jurnal Farmasi Vol 6, No 1 (2014): AS-SYIFAA Jurnal Farmasi Vol 5, No 2 (2013): AS-SYIFAA Jurnal Farmasi Vol 5, No 1 (2013): AS-SYIFAA Jurnal Farmasi Vol 4, No 2 (2012): AS-SYIFAA Jurnal Farmasi Vol 4, No 1 (2012): AS-SYIFAA Jurnal Farmasi Vol 3, No 2 (2011): AS-SYIFAA Jurnal Farmasi Vol 3, No 1 (2011): AS-SYIFAA Jurnal Farmasi Vol 2, No 2 (2010): AS-SYIFAA Jurnal Farmasi Vol 2, No 1 (2010): AS-SYIFAA Jurnal Farmasi Vol 1, No 2 (2009): AS-SYIFAA Jurnal Farmasi Vol 1, No 1 (2009): AS-SYIFAA Jurnal Farmasi More Issue