Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Indonesian Journal of Rheumatology

ijr
Website

Published by Indonesian Rheumatology Association

ISSN : 20861435 EISSN : 25811142 DOI : -

Core Subject : Health,

Medicine & Pharmacology

Indonesian Journal of Rheumatology is a peer-reviewed open access journal on rheumatic diseases and connective tissue disorders. This is an official journal of Indonesian Rheumatology Associantion (IRA) and published twice a year since 2009. Our mission is to encourage the development of scientific and medical practice in rheumatic diseases and connective tissue disorders. This journal is self-focused on rheumatic disease and connective tissue disorders in the form of original article (extended and/or concise reports), review articles, editorial letters, leaders, lesson from memorable cases, book reviews, and matter arising. Both in clinical and laboratory including animal studies.

Arjuna Subject : -

Articles 252 Documents

14 15 16 17 18

Mucocutaneous Manifestation of Systemic Lupus Erythematosus Patients At Rheumatology Outpatient Clinic In Dr. Hasan Sadikin General Hospital Chin Annsha Veimern; Ellyana Sungkar; Hartati Purbo Dharmadji; Laniyati Hamijoyo
Indonesian Journal of Rheumatology Vol. 9 No. 1 (2017): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune systemic disease which symptoms induced by Ultraviolet rays exposure. It commonly affects women and causes wide range of symptoms. One of the organs affected is mucocutaneous. Our study aims to determine mucocutaneous manifestations of SLE patients in Rheumatology Outpatient Clinic in Dr.Hasan Sadikin General Hospital, Bandung.Methods: A descriptive study with prospective crosssectional design conducted. Data were obtained by interviewing SLE patients as primary data and accessing medical record as secondary data. Ninety-six SLE patients met the inclusion and exclusion criteria wereincluded.Results: From ninety-six subjects, 94.8% subjects are working indoors. Mucocutaneous manifestation were found in most patients. Based on American College of Rheumatology (ACR) criteria, we found mucocutaneous manifestations, such as: oral ulcers in 67 patients(69.8%); malar rash in 63 patients (65.6%); photosensitivity rash in 51 patients (53.1%), and discoid rash erythematous in 21 patients (21.9%). Specific SLE cutanoeus manifestation based on Gilliam classification were found in our study subjects, such as papulosquamous/ psoriasisform (19.5%) , morbilliform (17.7%), vesicobullous annular SCLE (13.5%), annular SCLE (6.3%), and TEN-like LE (1%). Non-specific LE cutaneousmanifestations based on Gilliam classification were also found in our study subjects, such as oral ulcers (69.8%), photosensitivity rash (53.1%), alopecia (86.5%), Raynaudâ€™s Phenomenon (39.6%), nail abnormalities (24.0%), periungual telangiectasia patients (13.5%), vasculitic lesions (12.5%), thrombophlebitis (44.8%), bullous lesion (5.2%) and erythema multiforme (5.2%).Conclusion: Mucocutaneous manifestations in SLE patients based on ACR criteria found most in this study is oral ulcers. Based on Gilliam classification specific LE cutanoeus manifestation was not found in all SLE patients, while non-specific LE mucocutaneous manifestations mostly found is alopecia. Keywords: American College of Rheumatology (ACR) criteria, Gilliam classification, Mucocutaneous manifestations, Systemic Lupus Erythematosus

The Characteristic of Anti dsDNA and Organ System Involved in Systemic Lupus Erythematosus Patient at Hasan Sadikin General Hospital, Bandung Safira Nadifa; Achadiyani Achadiyani; Hartati Purbo Dharmadji; Laniyati Hamijoyo
Indonesian Journal of Rheumatology Vol. 9 No. 1 (2017): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Background : Clinical manifestation of Systemic Lupus Erythematosus (SLE) may be varies in attacking various body tissue and organ system. Anti-dsDNA is the important antibody indetermining diagnosis and prognosis of SLE. This study was conducted to explain the characteristics of antidsDNA and organ system involved in SLE patients.Method:Â We used quantitative descriptive analysis methods. Data were collected from medical records of SLE patients who came to Dr. Hasan Sadikin Bandung General Hospital Rheumatology Clinic from September to November 2016. Using categorical descriptive research equation, we found that total minimum samples were 67 subjects. Data observed included the level of anti-dsDNA antibody and clinical manifestation of organ systeminvolved.Result: From 67 samples, there were 65 females which accounted for 97% of the research subjects. Distribution of organ system involved in our subjects was musculoskeletal (29%), mucocutaneous (27%), hematologic (21%), kidney (15%), neuropsychiatry (4%),lung involvement (4%) and cardiovascular (0%). Organ system involved related with strong positive anti-dsDNA were mucocutaneous (21,6%), hematologic (25%), musculoskeletal (12,5%), kidney (14,3%) and lungs (20%).Conclusion:Â The most frequent organ system involved in SLE patients at our setting was musculoskeletal. The common organ involvement related with strong positive antidsDNA were mucocutaneous, musculoskeletal, and hematologic. Keywords: anti-dsDNA, involvement of organ system, clinical manifestation, systemic lupus erythematosus

Memory Performance in Patient with Systemic Lupus Erythematosus Using MoCA-Ina in Hasan Sadikin Genneral Hospital Bandung Safira Anjalia; Paulus Anam Ong; Nur Atik; Laniyati Hamijoyo
Indonesian Journal of Rheumatology Vol. 9 No. 1 (2017): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Background: The involvement of neuropsychiatry is reported in 6% to 91% of Systemic Lupus Erythematosus (SLE) patients. It can cause fatal morbidity and mortality. Memory impairment is one of the most common symptoms of neuropsychiatry involvement. This study aims to find out the performance of memory test in SLE patients using Indonesian version of Montreal Cognitive Assessment (MoCA-Ina).Method: This cross sectional study recruited 30 SLE patients. Cognitive abilities and patientâ€™s memory were examined using Indonesian version of Montreal Cognitive Assessment (MoCA-Ina). Cognitive impairment was determined when total MoCA-Ina score was below 26. For memory evaluation, immediate recall or delayed recall impairment was determined when the patient failed in each memory subtests.Results: The mean of total MoCA-Ina score was 24.97 (SDÂ±3.14). Fifty percent of the SLE patients had cognitive impairment, with the domain involved being delayed recall (86.67%), attention (60%), language (56.67%), abstraction (53.33%), and visuo-spatial/ executive function (36.67%). Most patients (86.67%) could completely repeat immediate recall. Whileonly 4 (13.33%) subjects could repeat delayed recall completely without any clue. Of the 26 SLE patients who failed to recall completely, 24 (92.3%) of them succeeded to recall completely after getting clue(s).Conclusion: Memory impairment is the most frequent cognitive impairment in SLE patients, especially in delayed recall. By using the memory subtests of MoCAIna, more than four fifth of patients with SLE was detected having delayed recall memory impairment and almost all of them could recalled completely after getting clue(s). This findings indicated that the finalstep of memory process retrieval in SLE was interrupted while being encoded, but retention pathway were stillintact.Keywords: Systemic Lupus Erythematous, Memory, MoCA-Ina

Interstitial lung disease in mixed connective tissue disease Marshell Tendean; Sazkia Aziza Nuriawan; Pringgodigdo Nugroho
Indonesian Journal of Rheumatology Vol. 9 No. 1 (2017): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Interstitial lung diseases (ILD) are known as a debilitating pulmonary complications that may be occured in almost all systemic connective tissue diseases (CTD), including mixed connective tissue disease (MCTD). ILD is usually found in more than half of MCTD patients after 2-4years after the diagnosis made. A-47-years-old female initially diagnosed as systemic lupus erythematosus (SLE) developed a severe progressive dyspnea. She has recently diagnosed as MCTD with ILD after 9 months of initial symptoms. She was giving with Cyclophosphamide 500 mg IV pulse dose. However, after 1 months she developed severe pneumonia andpronounced demise due to intractable septic shock. The debilitating course of ILD is commonly seen in most systemic CTD. Therefore, it is important to perform initial screening and prevention. Systemic corticosteroid with or without immunosupressor agent(s) are indicated inILD-MCTD. Patients with progressive diseases will have poor prognosis.Keywords : ILD, MCTD, Corticosteroid

The Pattern of Joints Involvement in Patients with Rheumatoid Arthritis in Rheumatology Clinic Dr. Hasan Sadikin General Hospital Bandung Muhammad Kevin Pratama; Nur Atik; Laniyati Hamijoyo
Indonesian Journal of Rheumatology Vol. 9 No. 2 (2017): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease with primary manifestation in the joints. Early management of RA will prevent further joint damage. The joint damages, result of uncontrolled disease activity, will decrease patientâ€™s quality of life.RA should be diagnosed earlier and followed by early treatment initiation, in order to prevent further damages. This study aimed to determine the pattern of joint involvement in RA in order to made earlier diagnosis and treatment initiation.Method: This research was conducted using descriptive study design. Data were obtained using interview of RA patients who coming to Rheumatology Clinic of Dr. Hasan Sadikin General Hospital from August 2016 to October 2016. Collected data included number of joints involvement, duration of therapy, and duration of illness after diagnosed according to the criteria of ACR / EULAR 2010.Result: Ninety-seven RA patients were involved in this study. Subjects were dominantly women (87%), the highest age group was 45-49 years old (17.53%), duration of the disease <5 years (90.72%), and duration of therapy > 3 months (86%). Joint that frequently involved at the time when the diagnosis made was first proximal interphalangeal (49.50%), overall findings during the course of RA was the wrist joint (90.72%).There were different tendency of joint involvement between the gender, knee joints occured in 53,84% male subjects, while PIP joints were accounted for 52,38% infemale subjects.Conclusion: The first PIP was the most common joint involved in RA patients when the diagnosis made. The wrist joint involvement was dominantly found in overall course of RA. Knee joint involvement was majorly found in male RA patients, whereas female RA patients would suffer mostly from PIP joint involvement.Keywords: involvement pattern, joints, rheumatoid arthritis

Correlation Between Serum Procollagen Type 1 N-Terminal Propeptide Level With Modified Rodnan Skin Score In Systemic Sclerosis Patients. Vincent Vincent; Sumartini Dewi; Rachmat Gunadi Wachjudi
Indonesian Journal of Rheumatology Vol. 9 No. 2 (2017): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Introduction: Systemic Sclerosis (SSc) is a chronic autoimmune disease, characterized by vasculopathy, specific autoimmune, and fibrosis. Assesment of skin fibrosis by modified Rodnan Skin Score (mRSS) can not detect the minimal changes of skin fibrosis within lessthan 3 months. A biomarker is needed to assess the minimal changes of skin fibrosis progressivity with a more objective, quantitative, and rapid way. Procollagen type-1 N-Terminal Propeptide (P1NP), a degradation product of collagen type-1, may become a potential biomarker for skin fibrosis. This study aims to evaluate the correlation between skin fibrosis by mRSS with P1NP serum in systemic sclerosis.Methods: This was a cross-sectional study performed among systemic sclerosis patients at Rheumatology outpatient clinic, Dr.Hasan Sadikin Hospital Bandung, from May 2016 to July 2016. Skin fibrosis was measured by mRSS. P1NP level was determined by ELISA. Data were analyzed using Rank-Spearman Correlation.Result: There were thirty-seven subjects, with mean age 37 (SD Â±7) years old. Most of subjects were female (91.9%). Subjects consisted of 23 (62.2%) limited SSc and 14 (37.8%) diffuse SSc. Six subjects (16.2%) were DMARD naÃ¯ve. We found median (range) P1NP serum was 43.85 (9.81-127.90) ng/dL, while the median of MRSS was 14 (3-36). There is a moderate correlation between MRSS and P1NP serum (r=0.443, p=0.003)Conclusion: There was a significant correlation between mRSS and P1NP serum in systemic sclerosis patient at Dr. Hasan Sadikin Hospital Bandung.Keywords: systemic sclerosis, P1NP, modified rodnan skin score

Most Frequent Musculoskeletal Manifestation of Systemic Lupus Erythematosus Patients in Dr. Hasan Sadikin General Hospital Bandung Rahadian Nugi Sutrisno; Andri Reza Rahmadi; Nita Novita; Laniyati Hamijoyo
Indonesian Journal of Rheumatology Vol. 9 No. 2 (2017): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease with wide range of clinical symptoms. The patients frequently complain musculoskeletal involvement during the active state of the disease. Musculoskeletal manifestation in SLE patients is an important sign in making early diagnosis and monitoring treatment response. This study aims to determine the presentation of musculoskeletal involvement of SLE patients in Dr. Hasan Sadikin General Hospital Bandung.Methods: a descriptive cross-sectional quantitative study done by interviewing SLE patients concerning musculoskeletal manifestation as the primary data and tracking their medical record as the secondary data. Study was conducted between September to November 2016 in Rheumatology Clinic Dr. Hasan Sadikin General Hospital Bandung.Result: Ninety-seven SLE patients, 91 females (93,81%) and 6 males (6,19%), were enrolled in this study with mean age 35.12 (Â±10.91) years. The three highest proportions of muskuloskeltal manifestations were arthritis of the knee (84,5%), myalgia of upper back(40,2%), and muscle weakness (15,5%). We did not find any Jaccoudâ€™s Arthropathy (JA) and tendinitis manifestation. Osteoporosis were occured in 4 patients (4,12%), whereas gout arthritis, spondytlitis, osteoarthritis, rotator cuff syndrome, and rhupus wereonly occured in one patient (1,03%), respectively.Conclusion: The common musculoskeletal manifestation in SLE patients were arthritis of knee, myalgia of upper back, and muscle weakness. Only small portion of patients suffered from osteoporosis, gout arthritis, spondytlitis, osteoarthritis, rotator cuff syndrome, and rhupus.Keyword: musculoskeletal manifestation, musculoskletal involment, SLE

Neuropsychiatric Manifestation Screening among Systemic Lupus Erythematosus Patients in Hasan Sadikin General Hospital Bandung Septian Dwi Putra; Mulya Nurmansyah Ardisasmita; Laniyati Hamijoyo
Indonesian Journal of Rheumatology Vol. 9 No. 2 (2017): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune diseases caused by deposition of immune complex with the involvement of various organ system and certain autoantibodies production. One of the most significant manifestation is neuropsychiatricsymptoms, known as NPSLE (Neuropsychiatric Systemic Lupus Erythematosus). This study aims to portray the distribution of neuropsychiatric manifestation of SLE patients using a screening method in Hasan Sadikin General Hospital.Method: An observative, descriptive categoric study, with consecutive sampling were done. Data were collected by spreading the questionnaire to subjects diagnosed as SLE who visiting Hasan Sadikin General Hospital during August-October 2016 and by tracingtheir medical records. Data analyzed included age, sex, education background, duration of lupus, diagnosis criteria, ongoing therapy, and neuropsychiatric manifestation.Result: Samples volunteered in this study were 97 patients. Of them 94 patients (96.9%) were women and 47 patients (48.5%) were senior high school graduated. Most common diagnosis criteria found was positive ANA test (91.8%). Most necessary ongoing therapygiven was methylprednisolone (96.9%). Common neuropsychiatric manifestations were mood disorders (73,2%), headache (57,7%), and mononeuropathy (51,5%).Conclusion: The common psychiatric, central nervous, and peripheral nervous manifestations were mood disorder, headache, and mononeuropathy, respectively.Keywords: Neuropsychiatry, NPSLE Screening,Systhemic Lupus Erythematosus

Overview of Anemia among Systemic Lupus Erythematosus Patients in Reproductive Age Women based on Reticulocyte Hemoglobin Equivalent (RET-He) Level and Reticulocyte Count Ismiana Fatimah Modjaningrat; Amaylia Oehadian; Mohammad Ghozali; Laniyati Hamijoyo
Indonesian Journal of Rheumatology Vol. 9 No. 2 (2017): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Background: Anemia is a common manifestation found among patients with Systemic Lupus Erythematosus (SLE). It may be caused by iron-deficiency, autoimmune hemolytic, and chronic inflammation. Each anemia has different therapy approachments. Without adequatemanagement, anemia may lead to poor prognosis. By identifying the etiology of anemia, appropriate management could be conducted. Reticulocyte Hemoglobin Equivalent (RET-He) and reticulocyte count test may distinguish anemia based on its etiology. This study aimed to give scientific portrayed of the proportion of anemia based on its etiology among patients with SLE using RET-He and reticulocyte count.Method: This study involved women diagnosed with SLE underwent outpatient treatment in Rheumatology Clinic, Dr. Hasan Sadikin General Hospital during SeptemberOctober 2016. Data were collected from blood exam using 35-parameters hematology Sysmex by calculating levels of hemoglobin, RET-He, and reticulocyte count.Results: Seventy four female patients were volunteered as subject in this study with median of age was 29.5 (16-70) years old. Thirty four (46%) of 74 subjects weresuffering from anemia and 12 (35%) of them were between 25-34 years old. Proportion of iron-deficiency anemia, autoimmune hemolytic anemia, and chronic inflammatory anemia were 14 ( 41%), 13 (38%), and 7 (21%), respectively.Conclusion: Based on hemoglobin, RET-He, and reticulocyte count, iron-deficiency anemia is the most common anemia among patients with SLE in repoductive age.Keyword: Age, Anemia, Reticulocyte, RET-He, Systemic Lupus Erythematosus (SLE)

Outcome of Pregnancy in Patients with Systemic Lupus Erythematosus Erica Kwan Yue; Coriejati Rita; Laniyati Hamijoyo
Indonesian Journal of Rheumatology Vol. 9 No. 2 (2017): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease which involves many different organ systems and immunological abnormalities. SLE mainly affects females in their reproductive age. This study aimed to describe the fetal outcome, neonatalcomplications, maternal outcome, and obstetrics complication in patients diagnosed with SLE, in order to help the physicians to reduce the fetal loss, improve maternal morbidity, and reduce neonatal or maternal deaths.Method: This research was conducted using descriptive quantitative design. Data were obtained from direct interview noted in a report form and medical records. Subjects were SLE patients who came to Rheumatology Outpatient clinic, Dr. Hasan Sadikin General Hospital, Bandung from September 2016 to November 2016; and fulfilled the inclusion and exclusion criteria. The minimal required sample was 96 subjects.Results: Due to time limitation, only 53 pregnancies from 40 females were managed to be recorded. The median age when being diagnosis of the subjects was 24 (14 - 41) years old. The fetal outcomes showed 64.2% live births, 18.9% spontaneous abortions, 9.4% intrauterine death, 1.8% intrauterine growth retardation, and 9.1% neonatal deaths. Neonatal complications included premature delivery, low birth weight, and growth retardation. Maternal complications during pregnancy included rash, pregnancy-inducedhypertension, arthritis, anemia, and thrombocytopenia. Furthermore, obstetric complications included 13.2% pre-eclampsia, 13.2% placenta previa, and 1.8% stroke.There were 2 cases (3.8%) of maternal death happened during the delivery.Conclusion: The most frequent maternal complications during pregnancy were arthritis and rash. Pre-eclampsia and placenta previa were the most frequent obstetric complications which experienced by the pregnant SLE patients. Exclude the live births, the most frequent fetal outcome was spontaneous abortion. The most frequent neonatal complications were preterm delivery and low birth weight.Keywords: pregnancy, systemic lupus erythematosus, fetal outcomes, maternal outcomes

Page 16 of 26 | Total Record : 252

14 15 16 17 18

Filter by Year

2009 2023

Filter By Issues

All Issue Vol. 15 No. 1 (2023): Indonesian Journal of Rheumatology Vol. 13 No. 3: Indonesian Journal of Rheumatology Vol. 14 No. 2 (2022): Indonesian Journal of Rheumatology Vol. 14 No. 1 (2022): Indonesian Journal of Rheumatology Vol. 13 No. 2 (2021): Indonesian Journal of Rheumatology Vol. 13 No. 1 (2021): Indonesian Journal of Rheumatology Vol. 12 No. 2 (2020): Indonesian Journal of Rheumatology Vol. 12 No. 1 (2020): Indonesian Journal of Rheumatology Vol. 11 No. 2 (2019): Indonesian Journal of Rheumatology Vol. 11 No. 1 (2019): Indonesian Journal of Rheumatology Vol. 10 No. 2 (2018): Indonesian Journal of Rheumatology Vol. 10 No. 1 (2018): Indonesian Journal of Rheumatology Vol 10, No 1 (2018) Vol 9, No 2 (2017) Vol. 9 No. 2 (2017): Indonesian Journal of Rheumatology Vol 9, No 1 (2017) Vol. 9 No. 1 (2017): Indonesian Journal of Rheumatology Vol. 8 No. 2 (2016): Indonesian Journal of Rheumatology Vol 8, No 2 (2016) Vol 8, No 1 (2016) Vol. 8 No. 1 (2016): Indonesian Journal of Rheumatology Vol 5, No 1 (2014) Vol. 5 No. 1 (2014): Indonesian Journal of Rheumatology Vol 4, No 1 (2013) Vol. 4 No. 1 (2013): Indonesian Journal of Rheumatology Vol 3, No 1 (2011) Vol. 3 No. 1 (2011): Indonesian Journal of Rheumatology Vol 2, No 3 (2010) Vol. 2 No. 2 (2010): Indonesian Journal of Rheumatology Vol 2, No 2 (2010) Vol. 2 No. 1 (2010): Indonesian Journal of Rheumatology Vol 2, No 1 (2010) Vol. 1 No. 2 (2009): Indonesian Journal of Rheumatology Vol. 1 No. 1 (2009): Indonesian Journal of Rheumatology Vol 1, No 1 (2009) More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota adm. jakarta pusat,

Dki jakarta

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

Contact Email -

Phone -

Journal Mail Official -

Editorial Address -

Location Kota adm. jakarta pusat, Dki jakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota adm. jakarta pusat,

Dki jakarta

INDONESIA