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INDONESIA
Indonesian Journal of Cardiology
Published by Indonesian Heart Association
ISSN : 28303105     EISSN : 29647304     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other health professionals for scientific articles in the cardiovascular field. All articles (research, case report, review article, and others) should be original and has never been published in any magazine/journal. Prior to publication, every manuscript will be subjected to double-blind review by peer-reviewers. We consider articles on all aspects of the cardiovascular system including clinical, translational, epidemiological, and basic studies. Subjects suitable for publication include but are not limited to the following fields: Acute Cardiovascular Care Arrhythmia / Cardiac Electrophysiology Cardiovascular Imaging Cardiovascular Pharmacotherapy Cardiovascular Public Health Policy Cardiovascular Rehabilitation Cardiovascular Research General Cardiology Heart Failure Hypertension Interventional Cardiology Pediatric Cardiology Preventive Cardiology Vascular Medicine
Arjuna Subject : Kedokteran - Cardiology and Cardiovascular Medicine
Articles 12 Documents
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Search results for , issue "Vol. 33, No. 1 Januari - Maret 2012" : 12 Documents clear
Teknologi Terkini dalam Tatalaksana Intervensi Non Bedah Penyakit Jantung Bawaan Radityo Prakoso; Dewi Hapsari Suprobo
Jurnal Kardiologi Indonesia Vol. 33, No. 1 Januari - Maret 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i5.67

Abstract

Dalam dua hingga tiga dekade terakhir bidang intervensi kardiak telah mengalami kemajuan yang pesat baik dalam hal jumlah tindakan dan jenis tindakan. Inovasi teknologi telah menopang kemajuan terapi intervensi non bedah penyakit kardiovaskular pada anak-anak dan usia dewasa. Terapi intervensi telah menjadi terapi alternatif yang cukup diterima pada kasus penyakit jantung bawaan, meliputi penutupan defek atrial (ASD), defek septum ventrikel tipe muskular (VSD muskular), duktus arteriosus paten (PDA), memperlebar stenosis aorta dan pulmonal seperti yang akan dibahas di bawah ini, sehingga pasien tidak selalu harus menjalani pembedahan. Adanya terapi intervensi non bedah ini juga sangat membantu mengurangi prosedur pembedahan yang diperlukan. Sedangkan pada beberapa kasus yang kompleks, apabila pendekatan secara per kutan sulit untuk dilakukan atau pasien juga membutuhkan perbaikan pada kelainan kardiak lain, pendekatan secara hibrid yaitu terapi intervensi bedah dikombinasi dengan intervensi perkutan dapat dilakukan pada penderita penyakit jantung bawaan.
Efek Ekstrak Kulit Manggis (Garcinia Mangostana Linn) sebagai Anti Inflamasi pada Tikus Model Aterosklerotik Salva Reverentia Yurista; Fathiyah Safithri; Djoni Djunaedi; Djanggan Sargowo
Jurnal Kardiologi Indonesia Vol. 33, No. 1 Januari - Maret 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i5.68

Abstract

Background. Atherosclerosis is an inflammatory disease characterized by intense immunological activity, which immune responses participate in every phase of atherosclerosis. On fundamental importance in atherogenesis is nuclear factor-?B(NF- ?B) that regulates activation of adhesion molecules (ICAM-1) and secretion of pro-inflammatory cytokines such as tumor necrosis factor(TNF-a) interleukin-1(IL-1), and interleukin-6(IL-6).Aims. The extract from pericarp of mangosteen (Garcinia mangostana Linn) were carried out to investigate for anti-inflammatory activity in rat models with atherosclerosis.Methods. The subjects of the study were 30 albino rats of (Rattus novergicus Strain wistar), divided into 5 groups with six rats in each group. Group I comprises normal healthy rats remains untreated for 90 days; Group II comprises of high cholesterol diet induced atherosclerotic rats for 90 days; Group III, IV, and V comprise of high cholesterol diet induced atherosclerosis and were administered extract from pericarp of mangosteen orally (200mg/kg; 400 mg/kg, 800 mg/kg) daily for 90 days. After 90 days treatment, rats were decapitated and blood was sample collected from the aorta for determination level of TNF-aand IL-1 by ELISA. Aorta was taken to observe the expression of NF-kB, ICAM-1, and IL-6 using immunohistochemical techniques.Results. Oral administration (800 mg/kg) of the extract from pericarp of mangosteen significantly decreased the level of TNF-a, and IL-1 and also reduced the expression of NF-kB, ICAM-1, and IL-6.Conclusion. These results suggest that the extract from pericarp of mangosteen (Garcinia mangostana Linn)possess anti-inflammatory actions by reducing level of TNF-a, IL-1, and also reduce the expression of NF-kB, ICAM-1, and IL-6 that prevent the development of atherosclerosis.
Obat Herbal untuk Aterosklerosis: Bagaimana Menyikapinya? Sunu Budhi Raharjo
Jurnal Kardiologi Indonesia Vol. 33, No. 1 Januari - Maret 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i5.69

Abstract

Salah satu tantangan besar bagi dunia medis tanah air adalah kenyataan tingginya animo masyarakat untuk pergi ke pengobatan komplementer (=alternatif ). Sebagai kardiolog, tidak jarang kita bertemu pasien yang menolak tindakan operasi atau pemasangan stent, dan memilih untuk pergi ke pengobatan komplementer. Fenomena ini tidak hanya ditemui di negara berkembang seperti Indonesia, tetapi juga di banyak negara maju. Perancis merupakan salah satu negara maju dengan jumlah warganya yang menggunakan jasa pengobatan komplementer paling besar (75%), disusul Inggris (UK) (50%) dan Kanada (42%).Di Amerika, menurut laporan National Center for Health Statistics, pada tahun 2007, setiap 4 dari 10 orang dewasa adalah konsumen pengobatan komplementer. Yang menarik, jumlah warga kulit putih yang menggunakan jenis terapi ini lebih banyak (43,1%) dibanding warga keturunan Asia (39,9%) dan warga kulit hitam (25,5%). Proporsi terbanyak masih dipegang orang Indian (50,3%). Laporan ini juga menunjukkan bahwa jenis pengobatan komplementer yang paling banyak digunakan adalah pengobatan herbal.
Gambaran Klinis, Tampilan Ekokardiografi, dan Prediktor dari Kejadian Emboli pada Endokarditis Infektif Muhammad Barri Fahmi; Teuku Istia Muda Perdan; Pranomo Sigit; Danayu Sanni Darmawan; Harmani Kalim; Eka Harmeiwaty; Amiliana Mardiyani; Ario Soeryo; Siska Suridanda; Ganesja M Harimurti
Jurnal Kardiologi Indonesia Vol. 33, No. 1 Januari - Maret 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i5.70

Abstract

Background. There are many risk factors that are associated with embolic events in patients with Infective Endocarditis (IE) ranging from infecting organism, valve location, vegetation morphology, to age. Nevertheless, echocardiography role in predicting embolic events in patients with Infective Endocarditis remains controversial. Some studies reported an increased risk of embolism in patients with large and mobile vegetations, whereas other studies failed to demonstrate such a relationship.Objectives. The aim of this study is to assess the risk factors that are associated with embolic events and to evaluate the role of transthoracic echocardiography (TTE) in predicting embolic events (EEs) in a small group of patients with definite endocarditis according to the Duke criteria.Methods. Subjects more than 17 years of age, who were enrolled in National Cardiac Center Harapan Kita Infective Endocarditis Registry and who had complete TTE recording were selected for this study. Fourteenpatients with definite Infective Endocarditis according to the Duke Criteria who were hospitalised within 2010 – 2011 were examined with M-mode and  two-dimension echocardiogram. The incidence of embolism was compared with the clinical and echocardiographic characteristics (localization and mobility) of the vegetations.Results. Among 14 patients, 5 (35,7%) had one or more EEs. There were no difference between patients with and without embolism in terms of infecting organism, gender and vegetation mobility. Five out of 9 patients (55%) with mitral valve involvement vegetation had EE. No patients with only aortic and tricuspid valve vegetations had EEs. And all of the patents with EE had mitral valve involvement. Thus, there was a significant higher incidence of embolism was present in patients with mitral valve involvement of vegetation (100%, p = 0,038). Conclusion. Our study shows that the involvement of mitral valve on TTE is predictive of embolism.
Is Left-Sided Infective Endocarditis Prone to Have Embolic Events? Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 33, No. 1 Januari - Maret 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i5.71

Abstract

Infective endocarditis (IE) is an endovascular microbial infection of intracardiac structures facing the blood including of large intrathoracic vessels and of intracardiac foreign bodies. Diagnostic and therapeutic improvement have been recently achieved, however it is still associated with high mortality and embolic events.A lot of studies have been done in search of high risk IE patient, mainly focus on echocardiographic findings. Unfortunatelly, those studies give rise conflicting results. In multicenter prospective European study, 384 consecutive patient with definite IE according to Duke criteria were followed up to 1 year. Using transesophageal echocardiography (TEE), they found that vegetation length is a strong predictor of new embolic event and mortality. In multivariate analysis, vegetation length of > 15 mm has an adjusted relative risk of 1.8 95%CI 1.1 to 2.82, p = 0.02. Combining clinical, microbiological and echocardiography finding may identify high risk patient who will need aggressive therapy.Stuby by Fahmi et al enrolled only limited number of definite IE patients and found that involvement of mitral valve, examined by transthoracal echocardiography (TTE), is a predictor of embolic events. As an initial study in this field among Indonesian subjects, we can compromize with the power of this study to conclude that left side valves involvement is a predictor of embolic event in IE patients. The conclusion it self is make sense in regard to the disease’s pathophysiology.
Perubahan Fungsi Ventrikel Kiri pada Penderita HIV Anggia Chairuddin Lubis; Abdullah Afif Siregar; Sutomo Kasiman
Jurnal Kardiologi Indonesia Vol. 33, No. 1 Januari - Maret 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i5.72

Abstract

Background. Patients with HIV have increased risk for myocardial dysfunction but the underlying mechanisms remain unknown.Methods & Results. This study evaluated noninvasively ventricular function in HIV infected patients with no clinical evidence of cardiovascular disease, with determination of left ventricular systolic and diastolic function, as well as measurement of CD 4. Between November 2009 and June 2010, 22 patients agreed to participate in a follow up study. All patients had normal LVEF and FS at both examinations. There was no evidence for a relationship between LVEF changes and either CD 4 changes, CD 4 nadir and HIV stadium. However an increase in mean EPSS was observed at follow up (p=0.045) and associated with lower CD 4 cell counts. At the initial visit, 1 patient had left ventricular dysfunction, and 4 patients at follow up. All patients had normal TAPSE values at both examinations.Conclusion. HIV related cardiomyopathy appears not to constitute a problem in HAART era. However subclinical cardiac abnormalities are frequently observed. The usefulness of systematic noninvasive screening in this population should be considered.
Ablasi Ventrikel Takikardia Outflow Tract Erika Maharani; Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 33, No. 1 Januari - Maret 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i5.73

Abstract

Tachycardia of right ventricular outflow tract (RVOT) is the most common cause of nonischemic ventricular tachycardia (VT). It is commonly due to idiopathic RVOT tachycardia. Idiopathic RVOT tachycardia is a nonfamilial and benign condition that occurs in young individuals without structural heart disease. Radiofrequency ablation has a high successful rate to eliminate this arrhythmia. Non contact mapping can be very helpful in patient with nonsustained tachycardias. We report the case of a 55-year-old man who presented with non sustained ventricular tachycardia and was successfully underwent radiofrequency ablation using non contact mapping.
CRISS - CROSS HEART (Laporan empat kasus) Anna Ulfah Rahajoe; Poppy S Roebiono; Muhammad B Fahmi; Ganesja M Harimurti
Jurnal Kardiologi Indonesia Vol. 33, No. 1 Januari - Maret 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i5.74

Abstract

Criss-cross heart is a rare congenital cardiac anomaly characterized by crossing of the inflow streams of the two ventricles. The anomaly seems to be due to abnormal twisting of the heart about its long axis and when the axis of the openings of the atrioventricular valves are not parallel. Thus in criss – cross heart the abnormality is on the atrioventricular relation, not connection, which happened due to clockwise or counter-clockwise ventricular rotation. We report four cases of criss-cross heart, three cases had levocardia - situs solitus with superior – inferior ventricles and one case had dextrocardia - situs inversus (mirror image) the ventricles were not in superior-inferior fashion. Subcostal and apical four-chamber views can be used to identify the ventricular morphology and position, the atrio-ventricular valves, the atrioventricular and ventriculo-arterial connection, and the characteristics of the great vessels. The artery connection can be seen more clearly in the parasternal window. All patients had concordance atrioventricular connection, ventricular septal defect and double outlet right ventricle with malposition of the great arteries. Other associated lesions included infundibular (subvalvular) and valvular pulmonary stenosis in three, atrial septal defect in two, and interrupted aortic arch with large persistent ductus arteriosus in one patient. The findings were confirmed by catheter-ization and angiography in three patients and multislice-CT in one.Conclusions.patients with criss-cross heart can be easily diagnosed by a careful, systematic segmental study with two-dimensional color-coded transthoracic echocardiography. The failure to obtain a characteristic four - chamber view in any cut and the presence of crossed atrioventricular inflow bloodstreams with each atrium draining into the ventricle located contralaterally were diagnostic for recognition of this complex anomaly. The presence of superior-inferior ventricles although suggestive, should not be regarded as diagnostic for criss cross anatomy.
Interferensi Elektromagnetik pada Pacu Jantung Sefri Noventi Sofia; Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 33, No. 1 Januari - Maret 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i5.75

Abstract

Increasing numbers of permanent pacemaker implantation in Indonesia raise the needs of electromagnetic interference (EMI) knowledge. EMI potentially result in pacemaker malfunction or failure that endangered the patient. This review discuss EMI sources that exist around patient daily live such as magnetic resonance imaging (MRI) examination, cellular phone, microwave oven, metal detector gate, elctrical cardioversion etc.
Terapi Sel Punca untuk Penyakit Jantung Vireza Pratama; Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 33, No. 1 Januari - Maret 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i5.76

Abstract

Despite a lot of advancesin current therapeutic modalities, heart failure and coronary artery disease are still the leading cause of morbidity and mortality. Current management of heart failure indeed increase survival rate, however re-hospitalization and mortality rate remain high. Furthermore, none of those therapeutic modalitiesare based on myocardial regeneration concept.Stem cell therapy is an interesting new concept in heart failure management. Various cell types, administration route and cell expansions strategies are extensively studied. Stem cell improve myocardial perfusion and differentiate into angiogenic and contractile cell. Stem cell therapy is a promising regeneratif medicine in the future.

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