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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 27 Documents
Search results for , issue " Volume. 4, No. 2, April 2016" : 27 Documents clear
Impact of Ethinyl Estradiol to Human Telomerase Reverse Transcriptase Activity on Complete Hydatidiform Mole Culture Nurseta, Tatit; Wijasa, Arsana; Sitompul, Barlian
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (136.508 KB) | DOI: 10.32771/inajog.v4i2.82

Abstract

Objective: To prove the effect of ethinyl estradiol as an activator on human Telomerase Reverse Transcriptase (hTERT). Method: The experimental study was conducted in vitro by using culture of complete hydatidiform mole trophoblast cell. We exposed the culture to ethinyl estradiol in varied doses and measured the concentration of hTERT through RT-PCR quantitative. There were 40 specimens as control group and 20 specimens exposed to ethinyl estradiol in different doses (10, 20, 40 and 80 mcg) as experimental group. The activity of hTERT was measured by RT-PCR and the concentration of it was assessed by ELISA. We analyzed the variables using ANOVA, Turkey post hoc and Pearson correlation test. Result: In control group, the concentration of hTERT was not detected. Meanwhile, the concentration among different doses of ethynil estradiol (10, 20, 40, 80 mcg) was 113,117.5; 114,507.6; 102,193.9; 127.546.1 amoles/ml, respectively. Among experimental group, they were significantly different both using F test (ANOVA) (p=0.001) and Turkey post hoc test (p=0.005). The correlation among group was 0.84 which meant higher level of ethinyl estradiol was correlated with higher activity of hTERT. Conclusion: Ethinyl estradiol impacts to the increase of hTERT activity on complete hydatidiform mole cell culture. [Indones J Obstet Gynecol 2016; 4-2: 93-96] Keywords: complete hydatidiform mole, ethinyl estradiol, human Telomerase Reverse Transcriptase (hTERT)
Female Sexual Function after Vaginal Delivery with Episiotomy and Cesarean Section Jembawan, I Made W
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (19.045 KB) | DOI: 10.32771/inajog.v4i2.407

Abstract

Objective: To determine the difference of sexual function after vaginal delivery with episiotomy and cesarean section in Sanglah Hospital, Denpasar. Method: This research was conducted using cross sectional method. Sample was collected using consecutive sampling, starting from October 2011-September 2012. Our sample consists of 86 women, 43 post-episiotomy and 43 post-cesarean section. Sexual function was assessed using FSFI (Female Sexual Function Index). Total score was analyzed using independent t-test and difference of sexual function was tested using Chi-square, with significance level p0.05). There was no significant difference between the two groups in term of sexual arousal and lubrication, with p-value 0.160 and 0.67, respectively. However, we found significant difference in other domains, namely desire (p=0.014), orgasm (p=0.045), satisfaction (p=0.018), pain (p=0.02), and total FSFI score (p=0.006). Sexual dysfunction was found in 18.60% of the episiotomy group and 2.33% of the cesarean section group, with p=0.030. Conclusion: Female sexual dysfunction was found to be significantly different between women post vaginal delivery with episiotomy and women who had cesarean section. [Indones J Obstet Gynecol 2014; 4: 199-203] Keywords: cesarean section, episiotomy, female sexual function
A1298C Polymorphism of Fetal Methylenetetrahydrofolate Reductase (MTHFR) Gene as a Risk Factor for Spontaneous Abortion Sulfiana, Isah; T Chalid, St Maisuri; Farid, Retno B; Rauf, Syahrul; Hartono, Eddy
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (86.87 KB) | DOI: 10.32771/inajog.v4i2.77

Abstract

Objective: To investigate the role of A1298C polymorphism of fetal methylenetetrahydrofolate reductase (MTHFR) gene in spontaneous abortion. Method: The case control study design recruited 96 subjects in Siti Fatimah and Pertiwi mother and child hospital, Dr. Wahidin Sudirohusodo, Pelamonia, Bhayangkara, Syekh Yusuf, Haji and Labuang Baji hospital from March to September 2014. All subjects fulfilling the inclusion criteria were taken tissue samples from mothers experiencing spontaneous abortion and blood samples from normally born baby. The data were analyzed using Pearson chi-square with significant rate of 5% (p
Transforming Growth Factor β1 and Tropoelastin Expression in Uterine Prolapse Alvilusia, Alvilusia; Fauzi, Amir; Azhari, Azhari; Wresnindyatsih, Wresnindyatsih; Saleh, Irsan
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (577.898 KB) | DOI: 10.32771/inajog.v4i2.78

Abstract

Objective: To know the correlation of the expression of transforming growth factor beta (TGF-β1) and tropoelastin in uterine prolapse. Method: A cross-sectional study of 30 subjects suffered from uterine prolapse in the Department of Obstetrics and Gynecology Dr. Mohammad Hoesin hospital Palembang. The study was conducted since December 1st, 2014 until July 31st, 2015. The sample was from the sacrouterine ligament and immunohistochemical examination was conducted to see the expression of TGF-β1 and tropoelastin. Result: Of the 30 subjects obtained, the expression of TGF-β1 was on 30 subjects consisting of 18 (60%) for weak expression and 12 (40%) for strong expression. Meanwhile, the strong tropoelastin expression was on 18 subjects (60%) and weak tropoelastin expression on 12 subjects (40%). There was a positive correlation between TGF-β1 and tropoelastin expression with moderate correlation (p=0.014; r=0.44). Conclusion: There is a positive correlation between the TGF-β1 and tropoelastin expression of sacrouterine ligament in uterine prolapse with moderate correlation. [Indones J Obstet Gynecol 2016; 4-2: 70-74] Keywords: transforming Growth Factor Beta 1, tropoelastin, uterine prolapse
Maternal Age, Abortion and Aneuploidy Hestiantoro, Andon
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (57.887 KB) | DOI: 10.32771/inajog.v4i2.74

Abstract

N/A
Prevalence of Postpartum Anxiety and Depression after Intrapartum Oxytocin Valentine, Grace; Kayika, I Putu G
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (91.861 KB) | DOI: 10.32771/inajog.v4i2.75

Abstract

Objective: To know the prevalence of postpartum anxiety and depression in patients who received intrapartum oxytocin. Method: Across-sectional observational study was conducted in Dr. Cipto Mangunkusumo hospital. Observation used Edinburgh Postnatal Depression scale and Beck Anxiety Inventory before delivery day, on the first and fourteenth day of postpartum. Result: Of 112 patients, we found the prevalence of mild and moderate anxiety were 94.6% and 5.4%. There were no anxiety women before delivery and on the first day of postpartum. The prevalence of mild and moderate anxiety on the fourteenth day of postpartum were 83% and 16.9%. There was no severe anxiety found at those time. On the other hand, the prevalence of postpartum depression on the first and fourteenth day of postpartum were 31.3% and 32.1%. There was no association between exogenous oxytocin and postpartum anxiety also depression. In multivariate analysis, we found that women with low self image were more prone to postpartum anxiety (OR 0.16, 95% CI 0.06-0.46). Meanwhile, postpartum depression was associated significantly to self image (OR 0.17, 95% CI 0.07-0.83), low income (OR 10.35, 95% CI 1.72-62.45) and pregnancy plan (OR 0.17, 95% CI 0.06-0.53) Conclusion: The patients who received intrapartum oxytocin are more prevalent to have mild anxiety. The prevalence of depression before delivery day, on the first and fourteenth day of postpartum are similar. In statistic, there is no relationship between intrapartum oxytocin administration and postpartum anxiety or depression. [Indones J Obstet Gynecol 2016; 4-2: 59-63] Keywords: anxiety, depression, oxytocin intrapartum, postpartum
Profile of Maternal Referral Cases Indarti, Junita; Ocviyanti, Dwiyana; Aditya, Reyhan
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (78.153 KB) | DOI: 10.32771/inajog.v4i2.76

Abstract

Objective: To explore the demography of maternal referral cases in Dr. Cipto Mangunkusumo Hospital (RSCM) along with the accuracy of referral. We also aim to evaluate the types of referral, origin of referral, referring healthcare facility and quality of referring healthcare facility. Method: The design of this study was a cross sectional design which described the accuracy of obstetrics referred cases in Emergency Unit Dr. Cipto Mangunkusumo Hospital from 2013 to 2014. Result: The total referred obstetric cases in 2013 was 1,645 patients. It was consisted of 1,307 appropriate (79.5%) and 338 inappropriate (20.5%) referred cases. Primary healthcare and general hospital were the most often referring cases to RSCM during two consecutive years. The top three cases referred to RSCM in both 2013 and 2014 were preterm premature rupture of membrane (PPROM), continued by severe preeclampsia and preterm labor. Conclusion: The number of referral cases in Indonesia is considered high, particularly in RSCM as the tertiary healthcare facility. There are still a high number of inappropriate referrals originating from primary healthcare facilities, pointing to the fact that the referral system is not running according to design or plan. To improve the quality of referral system, proper monitoring and evaluation of referral should be performed by local health department. [Indones J Obstet Gynecol 2016; 4-2: 64-66] Keywords: maternal case, referral system
A1298C Polymorphism of Fetal Methylenetetrahydrofolate Reductase (MTHFR) Gene as a Risk Factor for Spontaneous Abortion Sulfiana, Isah; T Chalid, St Maisuri; Farid, Retno B; Rauf, Syahrul; Hartono, Eddy
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (86.87 KB) | DOI: 10.32771/inajog.v4i2.77

Abstract

Objective: To investigate the role of A1298C polymorphism of fetal methylenetetrahydrofolate reductase (MTHFR) gene in spontaneous abortion. Method: The case control study design recruited 96 subjects in Siti Fatimah and Pertiwi mother and child hospital, Dr. Wahidin Sudirohusodo, Pelamonia, Bhayangkara, Syekh Yusuf, Haji and Labuang Baji hospital from March to September 2014. All subjects fulfilling the inclusion criteria were taken tissue samples from mothers experiencing spontaneous abortion and blood samples from normally born baby. The data were analyzed using Pearson chi-square with significant rate of 5% (p
Transforming Growth Factor β1 and Tropoelastin Expression in Uterine Prolapse Alvilusia, Alvilusia; Fauzi, Amir; Azhari, Azhari; Wresnindyatsih, Wresnindyatsih; Saleh, Irsan
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (577.898 KB) | DOI: 10.32771/inajog.v4i2.78

Abstract

Objective: To know the correlation of the expression of transforming growth factor beta (TGF-β1) and tropoelastin in uterine prolapse. Method: A cross-sectional study of 30 subjects suffered from uterine prolapse in the Department of Obstetrics and Gynecology Dr. Mohammad Hoesin hospital Palembang. The study was conducted since December 1st, 2014 until July 31st, 2015. The sample was from the sacrouterine ligament and immunohistochemical examination was conducted to see the expression of TGF-β1 and tropoelastin. Result: Of the 30 subjects obtained, the expression of TGF-β1 was on 30 subjects consisting of 18 (60%) for weak expression and 12 (40%) for strong expression. Meanwhile, the strong tropoelastin expression was on 18 subjects (60%) and weak tropoelastin expression on 12 subjects (40%). There was a positive correlation between TGF-β1 and tropoelastin expression with moderate correlation (p=0.014; r=0.44). Conclusion: There is a positive correlation between the TGF-β1 and tropoelastin expression of sacrouterine ligament in uterine prolapse with moderate correlation. [Indones J Obstet Gynecol 2016; 4-2: 70-74] Keywords: transforming Growth Factor Beta 1, tropoelastin, uterine prolapse
Factors Related to the Number of Antral Follicles on InVitro Fertilization (IVF) Raharja, Fransiskus C; Suwiyoga, Ketut; Wardhiana, IPG
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (86.67 KB) | DOI: 10.32771/inajog.v4i2.79

Abstract

Objective: To determine factors which are related to the number of antral follicles on infertile patients. Method: This cross sectional study was conducted in In-Vitro Fertilization (IVF) clinic of Graha Tunjung, Sanglah hospital, Bali. All fertile patients following the IVF program were calculated the number of antral follicles in both ovarian using transgene USG. This sample was recruited by random sampling from April 1st, 2001 to April 30th, 2011. We analyzed the data using Chi square test through SPSS for Windows 17.0 version. Result: Of 102 samples, the mean of patients’ age was 32.9% (SD 4.6) years old. From 72 patients (70.6%) experienced above 3 years of infertile period, the primary infertile was on 69 patients (67.7%). There was a relationship between patients’ age and the number of antral follicles significantly (prevalence ratio (PR) 1.41; 95% CI 1.11- 1.79). Meanwhile, the number of antral follicles and type of infertile (PR 1.02; 95% CI 0.76-1.37) also infertile period (PR 0.95; 95% CI 0.72-1.27) were not associated significantly. Conclusion: Patients’ age has an association with the number of antral follicles on IVF. [Indones J Obstet Gynecol 2016; 4-2: 75-77] Keywords: age, infertile, infertile period, number of antral follicles and type of infertile

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