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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,760 Documents
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Polimorfisme sebagai suatu uji genetik: Sebuah tinjauan kritis BAZIAD, A.
Indonesian Journal of Obstetrics and Gynecology Volume. 31, No. 2, April 2007
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (130.282 KB)

Abstract

Tujuan: Menelaah perkembangan penggunaan polimorfisme sebagai suatu uji genetik yang masih menimbulkan banyak silang pendapat. Rancangan/rumusan data: Kajian pustaka. Hasil: Gen terdiri dari berbagai variasi yang dapat menggambarkan berbagai jenis penyakit pada manusia dan dengan polimorfisme dapat juga menentukan dosis obat yang tepat bagi seseorang. Pengaruh lingkungan sangatlah besar terhadap gen. Polimorfisme yang ditemukan di suatu negara belum tentu sama dengan polimorfisme di negara yang lain, karena memang pengaruh lingkungan setiap negara berbeda-beda. Oleh karena itu sangat penting setiap negara memiliki sendiri-sendiri variasi gen. Kurang tepat kalau merujuk dengan variasi-variasi gen yang ditemukan di negara-negara maju. Kesimpulan: Pemeriksaan polimorfisme sangat berguna untuk menentukan apakah seseorang individu menderita penyakit tertentu, sehingga diharapkan dapat dilakukan pengobatan dan pencegahan dini. Dengan polimorfisme juga dapat ditentukan dosis obat yang tepat, mencegah efek samping yang tidak diinginkan. Namun polimorfisme telah menimbulkan kritik di berbagai negara. [Maj Obstet Ginekol Indones 2007; 31-2: 116-20] Kata kunci: polimorfisme, uji genetik
Motivation is the Strongest Influence in Choosing Delivery Place Astuti, Indria
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 4, October 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To analyze the factors that correlated with decision to choose the most appropriate delivery place of mothers’ delivery attended by health personnel, in West Bandung District. Method: This was a case-control study with consecutive sampling method on the mothers who gave birth at two health centers: Cikalong Wetan and Cipongkor, West Bandung District. There were two groups of mothers. First, the case group consisted of 52 mothers at non-healthcare facilities. Second, control group consisted of 52 mothers at healthcare facilities. There were sociodemographic (culture, educational), contextual (income, transportation, distance, availability health facilities) and characteristics of needs (counseling, prenatal care, motivation) factors and dependent variable was decision in choosing the place of delivery. The data was analyzed using chi square test to determine the correlation factors, whereas multiple logistic regression was used to determine the strongest correlating factors. Result: The results showed that there were correlation between various factors with the decision selection of delivery place of the mothers by health care in: cultural factor (OR = 23; p < 0.001; CI 95% : 7.99-66.20), educational factor (OR = 4.86; p < 0.001; CI 95% : 1.35- 19.09), income factor (OR = 2.36; p = 0.031; CI 95%: 6.51-57.49), transportation factor (OR = 19.35; p < 0.001; CI 95%: 6.51 to 57.49), distance factor (OR = 3.19, p = 0.007; 95% CI: 1.67-37.69), availability health facilities factor (OR = 7.94, p = 0.007; CI 95% 1.67-37.69 and OR = 3.97; CI 95% : 0.40-39.75), counseling factor (OR = 23, p < 0.001; CI 95%: 7.99-66.20), prenatal care factor (OR = 5.21, p < 0.001; 95%: 2.24-12.12), motivational factor (OR = 196, p < 0.001; CI 95 % : 41.64-922.48). The strongest factor was the motivational factor (OR = 103.33; p < 0.001; CI 95%: 10.00-1065.72). Conclusion: This study concluded that there was correlation between sociodemographic, contextual, and characteristics of needs with the decision in choosing place of delivery that attended by health personnel. Motivation was the strongest factor correlated to the mothers’ decision to deliver at public health center. [Indones J Obstet Gynecol 2013; 1-4:173-8] Keywords: characteristics of demand, contextual, delivery place, socio-demographic
Sexually Transmitted Infection in Correlation with Cervical Precancerous Lesion Indarti, Junita; Kurniawan, Riyan H; Nilasari, Hanny
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 1, January 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (136.048 KB) | DOI: 10.32771/inajog.v3i1.26

Abstract

Objective: To identify the correlation between sexually transmitted infection and cervical precancerous lesion. Method: The study design is cross‐sectional. Samples were collected by consecutive sampling method until the minimal amount was fulfilled. This study was conducted in the Colposcopy Outpatient Clinic and Cytology Laboratory, Division of Specialistic Gynecology, Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo Hospital (RSCM), Jakarta, from September 2008 to March 2009. Laboratory examination for sexually transmitted infection (STI) was performed in Department of Dermatovenereology, RSCM, Jakarta. Patients were grouped into cases and control group. The case group consisted of patients diagnosed with cervical intraepithelial neoplasia (CIN) and the control group consisted of patients without CIN. Sexually transmitted infection was identified and its relationship to CIN was analyzed. Result: We included 130 patients into this study, 25.38% without CIN and 74.62% with CIN. We found that one patient can be infected by up to five types of infection at a time. We also discovered a statistically significant relation between CIN 1 and STI (p=0.028), CIN 2 and STI (p=0.007), and CIN 3 and STI (p=0.013). Conclusion: Based on our study, we discovered a significant relationship between the incidence of STI and CIN. Keywords: cervical intraepithelial neoplasia, cervical precancerous lesion, sexually transmitted infection
The Impacts of Pelvic Floor Dysfunction Counseling to Knowledge Level and Attitude of Pregnant Women with Gestational Age above Thirty Six Weeks in the Selection of Delivery Method Hakim, Surahman; Ekaputra, Fajar
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 2, April 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (98.12 KB) | DOI: 10.32771/inajog.v5i2.527

Abstract

Objective: To determine the level of knowledge about pelvic floor dysfunction before and after counseling in term pregnant women and knowing whether a difference a change of attitude in the selection method of delivery before and after counseling. Methods: This study design using pre - post test. At the beginning of our study provide some sort of written test to determine the initial knowledge of participants prior to the extension and the selection of the desired method of delivery. Having obtained the results of the test, followed by education about pelvic floor dysfunction. Then do the post-test to determine the level of knowledge of the subject and mode of delivery that would be pursued. The study took place between February and May 2016 in 5 Public Health Center (PHC) in Jakarta that PHC Warakas (North Jakarta), PHC Tanah Abang (Central Jakarta), PHC Cengkareng (West Jakarta), PHC Jatinegara (East Jakarta) and PHC Jagakarsa (South Jakarta). Results: A total of 102 study subjects who began the study gave the results of the pretest mean 71  10.49 (p&lt;0.0001) and post test results of 80.725  7.7 (p&lt;0.0001). Of the 102 subjects who began the study, there were two people who had previously chose method of delivery by caesarean section turned into vaginal. Conclusion: There is a change scores better in knowledge about pelvic floor dysfunction after counseling. There was no significant difference between selecting the desired method of delivery before the after counseling. [Indones J Obstet Gynecol 2017; 5-2: 99-104] Keywords: fecal incontinence, pelvic floor dysfunction, sexual dysfunction, stress urinary incontinence, uterine prolapse
Correlation of Total Antioxidant Capacity Measured by Ferric Reducing Ability of Plasma (FRAP) Assay with the Severity of Preeclampsia Hermawan, Martin
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 4, October 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To analyze correlation between total antioxidant capacity measured by Ferric Reducing Ability of Plasma (FRAP) assay with severity of preeclampsia. Method: The cross sectional method was used in this study to compare TAC of four different groups of study, consists of normal pregnancy, mild preeclampsia, severe preeclampsia and eclampsia. The study consisted of 15 women in each group. All of the subjects met the inclusion criteria and were admitted to Dr. Hasan Sadikin Hospital and it’s district hospital. The study was conducted from August until September 2011. 3 ml blood samples were taken and were measured by FRAP assay in the laboratory PRODIA Jakarta. Result: There was no significant difference (p
Study of Apoptosis Induction of Hydatidiform Mole Trophoblastic Cell by the Administration of Retinoic Acid ANDRIJONO, ANDRIJONO; HEFFEN, W. L.
Indonesian Journal of Obstetrics and Gynecology Volume. 32, No. 2, April 2008
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Pendahuluan: Molahidatidosa merupakan kehamilan abnormal yang pada pemeriksaan histologi didapatkan proliferasi sel trofoblas. Sejumlah 80% penderita molahidatidosa akan mengalami regresi pascaevakuasi. Regresi spontan pascaevakuasi disebabkan karena sel trofoblas mempunyai aktivitas apoptosis. Sejumlah 20% penderita molahidatidosa menderita degenerasi keganasan yang secara klinis disebut PTG (Penyakit Trofoblas Ganas). Degenerasi keganasan ini mungkin disebabkan karena aktivitas proliferasi yang dominan sehingga proliferasi terjadi berkelanjutan pascaevakuasi. Mekanisme apoptosis pada molahidatidosa belum diketahui sepenuhnya. Asam retinoat yang merupakan zat aktif retinol atau vitamin A mempunyai aktivitas merangsang arest siklus sel dan merangsang apoptosis. Menarik untuk diteliti, apakah pemberian asam retinoat pada sel trofoblas molahidatidosa juga menginduksi apoptosis. Penelitian ini bertujuan membuktikan peningkatan aktivitas apoptosis pada sel trofoblas molahidatidosa yang diberikan asam retinoat. Penelitian ini memberi manfaat sebagai dasar penelitian kemoprevensi vitamin A pada molahidatidosa. Bahan dan cara kerja: Penelitian menggunakan spesimen kultur sel trofoblas molahidatidosa. Kultur sel trofoblas diperoleh dengan mengkultur sel trofoblas yang diperoleh dari gelembung molahidatidosa. Kultur dengan media RPMI. Pada usia 24 jam, dilakukan perlakuan dengan pemberian ATRA (all transretinoic acid) dengan dosis 50 μg/ml, 100 μg/ml, 150 μg/ml dan 200 μg/ml. Pelarut yang digunakan adalah DMSO (dimethyl sulfoxide). Dilakukan analisis aktivitas apoptosis dengan flowcytometry pada 24 jam pascaperlakuan. Aktivitas apoptosis tergambar pada sitogram di kwadran kanan bawah, sedangkan jumlah sel hidup pada kwadran kiri bawah. Perhitungan sel dilakukan pada 1000 sel. Hasil: Persentase apoptosis pada kontrol 60,64% sel hidup 7,09%. Persentase apoptosis pada 50 μg/ml 89,45%, 100 μg/ml sejumlah 87,23%, 150 μg/ml sejumlah 94.635 dan pada 200 μg/ml sejumlah 94,83%. Sedangkan sel hidup pada 50 μg/ml sejumlah 5,04%, pada 100 μg/ml 5,71%, pada 150 μg/ml sejumlah 3,14% dan pada 200 μg/ml sejumlah 2,66%. Kesimpulan: Terdapat peningkatan persentase jumlah sel yang apoptosis dan penurunan sel yang hidup pada sel trofoblas yang diberikan ATRA. [Maj Obstet Ginekol Indones 2008; 32-2: 99-104] Kata kunci: apoptosis, molahidatidosa, sel trofoblas, asam retinoat
Changes of Body Mass Index and Lipid Profile in Injectable Depot Medroxyprogesterone Acetate and Levonorgestrel Implant Acceptors Daido, Irwan; Tahir, Andi M; Chalid, St Maisuri T
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (119.243 KB) | DOI: 10.32771/inajog.v2i3.393

Abstract

Objective: To determine the comparison of body mass index (BMI) among acceptors of injectable depot medroxyprogesterone acetate (DMPA) with levonorgestrel implant acceptors for 1 year and comparison of lipid profiles between depot medroxyprogesterone acetate acceptors with levonorgestrel implants for 1 year. Method: This study was conducted at dr. Wahidin Sudirohusodo hospital, Makassar and its satellite hospitals as well as family planning social service cooperation between the National Family Planning Coordinating Board with the Department of Obstetrics and Gynecology Hasanuddin University. Result: The results showed the increase in BMI of levonorgestrel implant acceptors (1.25 kg/m2) was greater than DMPA acceptors (0.74 kg/m2). HDL cholesterol and triglycerides did not change significantly in either groups. LDL cholesterol was increased in DMPA acceptors (9.63 mg/dl) and decreased in implant acceptors (1.62 mg/dl). Total cholesterol increased in DMPA acceptors at 8.67 mg/dl) while in the levonorgestrel implant acceptors it was decreased by 5.37 mg/dl. Conclusion: Weight gain occured among acceptors of DMPA and implant however the weight gain is more profound among the implant acceptors. [Indones J Obstet Gynecol 2014; 3: 121-126] Keywords: body mass index, DMPA, levonorgestrel implant, lipid profile
CD4 Percentage and Absolute CD4 Accuracy not Different in Predicting Viral Load of HIVInfected Mothers Santoso, Ferry; Suwiyoga, Ketut; Putra, I Gede M
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.335 KB) | DOI: 10.32771/inajog.v3i4.59

Abstract

Objective: To determine the accuracy difference between CD4 percentage and absolute CD4 in predicting the viral load of HIV-infected pregnant women. Methods: This study is a diagnostic study involving 22 HIV-infected pregnant women who came for PMTCT at the Outpatient Clinic in Sanglah Hospital, from September 2011 until August 2012, who were randomly selected through consecutive sampling. Blood samples were collected to analyze the viral load, CD4, and complete blood count (CBC). Viral load examination was conducted using PCR in the molecular biology laboratory in the Faculty of Medicine University of Udayana. CD4 and CBC test was conducted in Sanglah Hospital Laboratory. Analysis was done with 2x2 table using SPSS for windows® version 17 to evaluate sensitivity, specificity and accuracy rate of CD4 percentage and absolute CD4 in predicting the viral load. Results: Data analysis shows that CD4 percentage had 75.0% sensitivity, 88.9% specificity, and accuracy of 86.4% for predicting the viral load in HIV-infected pregnant women. Meanwhile, absolute CD4 had 50.0% sensitivity, 77.8% specificity, and 72.7% accuracy. Chisquare test shows that there was no significant difference in the accuracy of CD4 percentage and absolute CD4 (p=0.457). Conclusion: CD4 percentage and absolute CD4 had high accuracy in predicting the viral load in HIV-infected pregnant women (86.4% and 72.7%). There was no significant difference of accuracy between the CD4 percentage and absolute CD4. [Indones J Obstet Gynecol 2015; 3-4: 230-233] Keywords: CD4, HIV-infected pregnant women, viral load
Evaluation of Obstetric Emergency Referral Cases at Dr. Cipto Mangunkusumo Hospital January - December 2008 Purnama, Dian Indah
Indonesian Journal of Obstetrics and Gynecology Volume. 34, No. 4, October 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To have description and evaluation about obstetric emergency referral cases at obstetric emergency room of Dr. Cipto Mangunkusumo Hospital (RSCM) from January until December 2008. Method: This is a cross-sectional descriptive-analytic study with 458 secondary data samples from simple random sampling performed to all obstetric referral cases at obstetric emergency room of RSCM from January until December 2008. The data were pro-cessed for frequencies and bivariate analysis, and then further analyzed with multivariate analysis. Results: Patients’ age varied between 16 to 47 years old (27.78 ± 6.51). Grandemultiparous women had 51.9% morbidity/mortality (p = 0.024). Midwives were the majority of referee (73.1%), but 71.1% main obstetric emergency cases were referred by Ob/Gyn. There were 260 cases corresponded to main obstetric emergency with 88 cases diagnosed as hypertension. Most of the cases were referred due to threatened preterm labor (22.5%), with 74.7% reasons for referral were ’lack of facility’. Most of the cases had no complete referral record (91% cases had no referral time and 12.4% cases had no initial assessment). Our hospital’s mean response time was 8 minutes. From multivariate analysis, referee (OR for doctors and Obstetricians 2.751; 95% CI 1.475 - 5.129) and delivery method (OR for spontaneous delivery 0.412; 95% CI 0.227 - 0.750) were two most influent variables for obstetric emergency referral cases outcome. The MMR for this study was 253.2/100.000. Conclusion: Our referral system is still not efficient. It needs improvement and continuous input and facility fulfillment. [Indones J Obstet Gynecol 2010; 34-4: 164-9] Keywords: referral system, maternal mortality ratio, referral time, response time
Prevalensi infeksi klamidia pada jaringan serviks dan jaringan tuba dan sebarannya menurut faktor demografi dan faktor risiko lain di kalangan pasien kehamilan tuba terganggu (Studi Epidemiologi di RSCM) EMERALDI, M.
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 2, April 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (44.73 KB)

Abstract

Tujuan: Penelitian ini memiliki tujuan utama untuk mengetahui prevalensi infeksi klamidia di jaringan serviks dan jaringan tuba dengan menggunakan metode pemeriksaan Polymerase Chain Reaction (PCR), dan bersamaan dengan itu dicoba untuk diketahui sebarannya menurut faktor demografi dan faktor risiko di kalangan pasien dengan kehamilan tuba terganggu. Rancangan/rumusan data: Studi potong lintang (cross sectional). Bahan dan cara kerja: Penelitian ini dilakukan dari bulan Maret 2008 sampai Agustus 2008 terhadap 25 subjek penelitian yang memenuhi kriteria inklusi dan menjalani operasi salpingektomi pengangkatan tuba) di Instalasi Gawat Darurat Rumah Sakit Dr. Cipto Mangunkusumo. Semua subjek penelitian mengisi formulir persetujuan, melakukan pengisian kuesioner berdasarkan anamnesis dan pemeriksaan ginekologi, kemudian dilakukan pengambilan swab serviks dan sampel jaringan tuba untuk dilakukan deteksi infeksi klamidia dengan menggunakan metode PCR. Hasil dan kesimpulan: Didapatkan prevalensi infeksi klamidia trakomatis di jaringan serviks dan jaringan tuba pada pasien dengan kehamilan tuba terganggu adalah 12% (3/25) dan 4% (1/25). Dari hasil anamnesis dan pemeriksaan fisik saat datang, didapatkan kecenderungan peningkatan risiko infeksi klamidia di serviks pada usia di atas 31 tahun, status pendidikan SD-SLP, usia di atas 21 tahun saat melakukan hubungan seksual, riwayat infertilitas, riwayat keputihan, riwayat infeksi kemih, dan servisitis walaupun secara statistik tidak bermakna. [Maj Obstet Ginekol Indones 2009; 33-2: 80-6] Kata kunci: kehamilan tuba terganggu, infeksi klamidia trakomatis, PCR

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