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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,760 Documents
Penilaian Pengetahuan, Sikap, dan Perilaku Pasien Poliklinik Kebidanan dan Kandungan RSUPN Dr. Cipto Mangunkusumo Tentang Pap Smear MOEGNI, E. M.
Indonesian Journal of Obstetrics and Gynecology Volume. 30, No. 4, October 2006
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Untuk mengetahui pengetahuan, sikap dan perilaku pasien poliklinik tentang pap smear. Tempat: Poliklinik Departemen Obstetri dan Ginekologi Fakultas Kedokteran Universitas Indonesia/ RSUPN Dr. Cipto Mangunkusumo. Bahan dan cara kerja: Penelitian ini menggunakan metode pengumpulan data dengan cara convenience sampling. Pengambilan data dilakukan dengan cara wawancara terpimpin menggunakan kuesioner yang telah diuji coba sebelumnya. Hasil: Data yang berhasil diperoleh adalah 102 responden yang memenuhi kriteria. Dari 102 responden disimpulkan bahwa sebagian responden berusia 21 - 39 tahun, berpendidikan menengah, tidak bekerja dan berpendapatan keluarga menengah rendah. Sebanyak 89,9% responden mempunyai tingkat pengetahuan tentang kanker serviks yang buruk, khususnya mengenai definisi, faktor risiko, gejala dan cara deteksi dini. Responden yang berpengetahuan baik mengenai pap smear hanya 2,9% dan hanya 11,8% yang berperilaku baik. Sedangkan sikap responden umumnya baik (87,3%). Sebagian besar pengetahuan, sikap dan perilaku (PSP) responden mengenai pap smear tergolong buruk (72,5%). Kesimpulan: Perlu dilakukan peningkatan pemberian informasi tentang kanker serviks dan pap smear pada masyarakat secara interpersonal melalui keluarga, teman, (peer educator) dan terutama petugas medis (dokter, perawat, bidan). Serta kemudahan untuk mengakses informasi tentang kanker serviks dan pap smear secara luas melalui media cetak, media elektronik dan penyuluhan oleh berbagai pihak. [Maj Obstet Ginekol Indones 2006; 30-4: 213-8] Kata kunci: kanker serviks, pap smear, PSP pasienbf
Women in the Rural Areas Experience more Severe Menopause Symptoms Yohanis, Mono
Indonesian Journal of Obstetrics and Gynecology Volume. 37, No. 2, April 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: The aim of this study is to compare the severity of menopausal symptoms between menopause women who lived in urban area with those who lived in rural area. Methods: The study is conducted by comparing the scores of Menopause Rating Scale (MRS) and World Health Organization Quality of Life (WHOQOL) questionnaires of menopause women who lived in the City of Makassar with those who lived in rural areas of Selayar. Results: The results of the study revealed that menopausal symptoms are more severe on menopause women who lived in rural areas than those who lived in urban area. Less educated menopause women have more severe menopausal symptoms than those who have more education. Their Quality of Life show no significant difference. There is a correlation between the severity of menopausal symptoms with the quality of life of menopause women, the more severe the symptoms, the less the quality of life are. Conclusion: Menopausal symptoms are more severe on menopause women who lived in rural areas than those who lived in urban area. [Indones J Obstet Gynecol 2013; 37-2: 86-91] Keywords: menopausal symptoms, rural area, urban area
Kematian Ibu di Indonesia Dapatkah kita mencapai target MDGs 2015?* SAIFUDDIN, A.B.
Indonesian Journal of Obstetrics and Gynecology Volume. 30, No. 1, January 2006
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan kita masih jauh, sementara waktu tinggal 10 tahun. Dapatkah kita mencapai target yang telah disepakati AKI 125/100.000 pada 2010 dan 100/100.000 pada 2015? Padahal, saat ini masih 307/100.000? Kalau cara kerja kita masih seperti sekarang, sudah dapat dipastikan kita akan gagal. Oleh karena itu, kita harus berubah. Teknologinya sudah tersedia, tinggal membenahi sistem dan orangnya. Kalau Cina yang sebesar itu mampu atau Srilanka yang sedemikian miskin sudah berhasil, mengapa kita harus gagal?
Comparison of administration of estradiol valerat 1 mg and 2 mg to improve squamous epithel maturation of Pap Smear preparation on postmenopausal women Purnamaningsih, Ika Sri
Indonesian Journal of Obstetrics and Gynecology Volume. 34. No. 2, April 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To determine the most effective dose of estradiol valerat (daily oral administration of 1 mg or 2 mg for 14 days) to improve squamous epithel maturation of Pap Smear on postmenopausal women. Method: Seventy one postmenopausal women with atrophic Pap Smear were participated in this randomized double blind clinical trial. 35 subjects received estradiol valerat 1 mg and the other 36 subjects received estradiol valerat 2 mg. After daily oral administration of estradiol valerat for 14 days, second Pap Smear were performed to evaluate epithel maturation. The side effects were also evaluated in this study. Result: There were 5 subjects whom lost to follow up due to refused to perform second Pap Smear and 1 subject was drop out due to nausea. 65 subjects were included in final analysis. Estradiol valerat 2 mg was significantly more effective than estradiol valerat 1 mg in improving epithel maturation of Pap Smear preparation on postmenopausal women. There were no complain about nausea and vaginal bleeding. Leukorhea occurred more frequently in the 2 mg group. Conclusion: Daily oral administration of 2 mg estradiol valerat was more effective than estradiol valerat 1 mg in improving squamous epithel maturation of Pap Smear on postmenopausal women with minimal side effect (leukorhea). [Indones J Obstet Gynecol 2010; 34-2: 89-91] Keywords: Pap Smear, postmenopausal women, estradiol valerat, epithel maturation of Pap Smear
Effect of Anti Zona Antibody on In Vitro Growth and In Vitro Maturation of Intact Follicles WIWEKO, B.; NATADISASTRA, M.; HORTENCIA, G. C.; HASEGAWA, A.; KOYAMA, K.
Indonesian Journal of Obstetrics and Gynecology Volume. 31, No. 4, October 2007
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Mengetahui pengaruh antibodi anti zona pellucida terhadap perkembangan (in vitro growth = IVG) dan pematangan (in vitro maturation = IVM) folikel. Tempat: Laboratorium biologi dan reproduksi Fakultas Kedokteran Hyogo, Nishinomiya, Jepang. Rancangan/rumusan data: Studi eksperimen pada hewan coba. Bahan dan cara kerja: Dilakukan pengambilan 80 folikel intak secara mekanik dari ovarium mencit (C57BL/6 x DBA2-F1 mice) usia 16 hari kemudian dilakukan inkubasi pada medium yang mengandung antibodi anti zona pellucida selama 8 hari. Antibodi ini diambil dari kelinci yang disuntikkan komponen ZPA dan ZPC mencit. Serum kelinci normal digunakan sebagai kontrol. Folikel dikelompokkan menjadi 4 kelompok dengan masing-masing terdiri dari 20 folikel. Kelompok 1 sebagai kontrol, kelompok 2 diinkubasi dengan serum kelinci normal, kelompok 3 diinkubasi dengan anti ZPA dan kelompok 4 diinkubasi dengan anti ZPC. Setelah 8 hari seluruh folikel dipindahkan ke medium IVM untuk dinilai perubahannya menjadi folikel antral. Hasil: Secara morfologis tidak dijumpai perbedaan bermakna pada perkembangan folikel antara kelompok kontrol dan perlakuan. Tetapi antibodi anti zona pellucida mempengaruhi perkembangan folikel antral pada kelompok perlakuan. Secara statistik dijumpai perbedaan bermakna dalam jumlah folikel antral antar kelompok 3 dan 4 dengan kelompok 1 dan 2. Pada kelompok 3 (anti ZPA) 9 dari 20 folikel (45%) berkembang menjadi folikel antral sedangkan pada kelompok 4 (anti ZPC) 11 dari 20 folikel (55%) berkembang menjadi folikel antral, dibandingkan dengan kelompok 1 dan 2, masing-masing 100% dan 85% folikel pre antral berkembang menjadi folikel antral. Kemudian seluruh folikel antral ditransfer ke medium IVM dan diinkubasi selama 16-17 jam. Pada kelompok 1, 100% folikel mengalami mucifikasi, sedangkan pada kelompok 2, 3 dan 4 masing-masing sebesar 75%, 55% dan 15% folikel mengalami mucifikasi. Setelah dilakukan denudasi germinal vesicles (GV) dijumpai sebanyak 5% pada kelompok 1,5% pada kelompok 2, dan 10% pada kelompok 4. Sedangkan pada kelompok 3 tidak dijumpai GV. Metafase 1 dijumpai sebanyak 40% pada kelompok 1,35% pada kelompok 2,50% pada kelompok 3 and 50% pada kelompok 4. Sedangkan metafase 2 dijumpai sebanyak 55% pada kelompok 1,60% pada kelompok 2, dan 40% pada kelompok 3. Tidak dijumpai metafase 2 pada kelompok 4. Beberapa oosit yang berdegenerasi dijumpai pada kelompok 2 (5%), kelompok 3 (5%) dan kelompok 4 (30%). Terdapat perbedaan bermakna dalam hal pematangan folikel (IVM) antara kelompok kontrol dan perlakuan. Kesimpulan: Antibodi anti zona pellucida mempengaruhi proses perkembangan dan pematangan folikel in vitro. Efeknya pada fertilisasi masih harus diteliti lebih lanjut. [Maj Obstet Ginekol Indones 2007; 31-4: 226-30] Kata kunci: folikel intak, perkembangan folikel (IVG), pematangan folikel (IVM), antibodi anti zona pellucida, folikel antral, mucifikasi, germinal vesicles, metafase-1, metafase-2
Maternal Cystatin C Serum is Higher in Women with Severe Preeclampsia Isasari, Kurnia M.
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 1, January 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To determine the comparison between maternal cystatin C serum in severe preeclampsia and normal pregnancy. Method: This was an observational study with cross sectional analytic approach. The subjects are sixty women with severe preeclampsia and normal pregnancy who met inclusion criteria. The maternal serum level of cystatin C was automatically measured with Particle Enhanced Nephelometric Assay (PENIA). Result: Mean serum level of cystatin C in severe preeclampsia was 1.169 ± 0.311 mg/l. Mean serum level of cystatin C in normal pregnancy was 0.929 ± 0.166. There was a significant differences between maternal serum levels of cystatin C in women with severe preeclampsia compared with women with normal pregnancy. Conclusion: There was a significant differences between maternal serum levels of cystatin C in severe preeclampsia compared with normal pregnancy. [Indones J Obstet Gynecol 2014; 2-1: 22-27] Keywords: cystatin C, endotheliosis glomerulus, severe preeclamp
Female Sexual Function at Three Months Post-delivery in Spontaneous Labor and Cesarean Section Suntoro, Suntoro; Kayika, I Putu G
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 3, July 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (93.8 KB) | DOI: 10.32771/inajog.v3i3.41

Abstract

Objective: To study the comparison of encouragement, stimuli, orgasm, pain and satisfaction of female sexual function at 3 months postpartum between spontaneous delivery and cesarean section in Dr. Cipto Mangunkusumo Hospital in Jakarta. Method: This was an observational research, sexual function was measured at three months post-delivery with Female Sexual Function Index (FSFI) questionnaire. The study design used was cross sectional with consecutive sampling. Analysis for comparative nonpaired categorical variables was done using Chi square or Fisher analysis. Analysis for confounding variables was carried out using multivariate logistic regression. Result: From 150 respondents, 43.3% had sexual dysfunction, with 52% of the spontaneous labor group and 34% of the cesarean section group. Bivariate analysis showed that occurrence of sexual dysfunction at three months post-spontaneous labor was 1.5 times higher (95% CI 1.02-3.19) compared with cesarean section. Sexual encouragement shows a two-fold difference (95% CI 1.17-3.40) compared to cesarean section. However, orgasm disturbance was 8 times higher (95% CI 1.90-3.58) in the spontaneous labor group, with confounding variable of perineal rupture. Disturbance of sexual stimuli, satisfaction, and pain were not significantly different between spontaneous labor and cesarean section. Multivariate analysis found that spontaneous labor was statistically significant for sexual dysfunction at three months post-delivery in patients with sexual encouragement (RR=2.716, p=0.008) and orgasm accession dysfunction (RR= 6.952, p=0.031). However, the more than 30 years old of age variable was statistically significant in sexual dysfunction variable with RR= 2.60 and p=0.021. Conclusion: Spontaneous labor is statistically significant for sexual dysfunction at three months post-delivery, especially for sexual encouragement and orgasm accession. Meanwhile, the variables with the age of 30 years old or older of age were influential on sexual dysfunction, especially to the sexual stimuli variable. Keywords: labor method, sexual dysfunction, three months postdelivery
Prevalence and Characteristics of Pelvic Floor Dysfunction in a Tertiary Care Center in Indonesia Santoso, Budi I; Fauziah, Nur R
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 3, July 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (93.84 KB) | DOI: 10.32771/inajog.v5i3.546

Abstract

Objective: To determine the prevalence and characteristics of pelvic floor dysfunction (PFD) in Jakarta, Indonesia. Methods: A cross sectional study was conducted at gynecology, endocrinology, and urogynecology clinic of Dr. Cipto Mangunkusumo Hospital during the period from January 2016 to April 2016. Subjects were selected using consecutive sampling. Data were taken using research and POP-Q form. Results: A total of 197 subjects were recruited. The prevalence of patients with PFD was 33%. The prevalence of POP, UI, and FI were 26.4%, 15.3% and 2.5%; respectively. Association between individual characteristics and PFD was found on women aged ≥ 60 and aged 40-59 years old with 69 and 14 times probability to be PFD. The probability of developing PFD was 76 and 14.2 times in multiparity and primiparity. Woman with vaginal delivery had a change to develop PFD 1.9 times and postmenopausal woman had a probability 18 times. The infuencing risk factor in PFD were age parity, race, mode of delivery, and menopausal status. Conclusion: Pelvic floor dysfunction affects a substantial of women and increases with age, parity and aging. [Indones J Obstet Gynecol 2017; 5-3: 168-172] Keywords: fecal incontinence, pelvic floor dysfunction, pelvic organ prolapse, urinary incontinence
Malaria Detection using Polymerase Chain Reaction (PCR) Method in Pregnant Women’s Saliva on Several Hospitals in North Sulawesi Province Khrisnamurti, Dewanto
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 1, January 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To detect malaria by PCR examination of saliva in pregnant women and to obtain the incidence of malaria and the type of plasmodium causing malaria in pregnant women at various hospital in North Sulawesi. Method: A descriptive cross sectional study in pregnant women during antenatal care at the Department of Obstetrics and Gynecology Faculty of Medicine University of Sam Ratulangi/Prof. Dr. R.D. Kandou General Hospital in Manado, R.W. Monginsidi Hospital in Manado, Bethesda Hospital in Tomohon, and Datoe Binangkang Hospital in Kotamobagu, from 1 April until 31 May 2008. Result: There were 43 pregnant women clinically diagnosed with malaria, 23 (53.49%) by PCR examination of saliva and 20 (46.59%) by blood smears. From 23 cases of malaria in pregnancy detected by PCR, there were 18 diagnosed as tropical malaria, 3 tertian malaria, and 2 mixed malaria. Conclusions: The incidence of malaria in pregnancy at various hospital in North Sulawesi using PCR methods for saliva examination from April 1 - May 31 2008 is 53.49%. In this study malaria are mostly caused by Plasmodium falciparum with the largest incidence in primigravida, in the first trimester. [Indones J Obstet Gynecol 2012; 36-1:14-9] Keywords: malaria, PCR, pregnancy, saliva
Hubungan ekspresi Her-2/neu dan p53 terhadap respons terapi dan kelangsungan hidup penderita kanker ovarium jenis epitel HIDAYAT, Y. M.; ANDRIJONO, ANDRIJONO; MIHARDJA, S. G.; SIREGAR, B.
Indonesian Journal of Obstetrics and Gynecology Volume. 32, No. 4, October 2008
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Untuk mengetahui adanya over ekspresi Her-2/neu dan p53 pada penderita kanker ovarium jenis epitel yang telah dilakukan operasi dan kemoterapi di RSCM dan hubungannya dengan derajat keganasan histopatologi, respons kemoterapi dan survival 1 tahun, 3 tahun, dan 5 tahun. Bahan dan cara kerja: Penelitian ini merupakan penelitian potong lintang dengan historical cohort untuk mendapatkan gambaran prevalensi over ekspresi Her-2/neu dan p53 pada penderita tumor ganas ovarium jenis epitel, faktor-faktor risiko klinis, derajat keganasan histopatologis dan bagaimana hubungan faktor-faktor risiko tersebut dengan keberhasilan terapi yang telah diberikan dan survival 1 tahun, 2 tahun, dan 5 tahun di RSCM dari Januari 1999 sampai Desember 2003. Hasil: Sejak Januari 1998 sampai 31 Desember 2003, dapat dikumpulkan 178 kasus kanker ovarium jenis epitel sesuai pemeriksaan histopatologi di Bagian Patologi Anatomi FKUI. Dari 178 kasus tersebut yang dapat dimasukkan ke dalam penelitian ini sesuai dengan kriteria inklusi sebanyak 34 kasus (telah memenuhi minimal sampel 30 kasus). Pada analisa data demografi ternyata insidensi terbanyak pada usia ratarata penderita 45,7 tahun dan sebagian besar kasus datang ke RSCM pada stadium lanjut 64,7% dengan jenis tipe sel yang mempunyai perangai buruk 41,4% (clear cell/small cell, adenocarcinoma, dan undifferentiated). Pada penelitian ini didapatkan angka survival penderita karsinoma ovarium, survival ≥ 1 tahun (70,5%), survival ≥ 3 tahun (47,1%), dan survival ≥ 5 tahun (41,2%), sedangkan prevalensi over ekspresi pada subjek penelitian sebanyak 8,8%, lebih rendah dari yang didapatkan peneliti-peneliti lain. Ekspresi protein gen p53 positif (+1, +2, +3) didapatkan sebanyak 50% dan negatif ekspresi 50%. Pada analisa korelasi dengan berbagai variabel klinis, yakni tipe sel, diferensiasi sel, stadium, respons kemoterapi, lama bebas penyakit dan survival 1 tahun, 2 tahun, dan 5 tahun tidak tampak perbedaan yang berarti, distribusi pada ekspresi Her-2/neu dan p53 positif dan negatif hampir merata. Tidak terbukti adanya perbedaan yang bermakna dengan p > 0,05. Sedangkan hubungan variabel klinis dengan respons kemoterapi dan survival pada penelitian ini memperlihatkan perbedaan yang cukup bermakna misalnya pada pembedahan komplit memberikan angka survival 1 tahun, 3 tahun, dan 5 tahun yang lebih baik dibandingkan sitoreduksi sub-optimal terbukti dengan analisa statistik koefisien korelasi rank spearman didapatkan angka rs = 0,450 dengan p = 0,011 (p < 0,05). Kesimpulan: Ditemukan angka prevalensi over ekspresi protein gen Her-2/neu di RSCM (+2) 8,8% dan ekspresi protein gen p53 50%. Pada penelitian ini tidak ditemukan hubungan bermakna antara over ekspresi protein gen Her-2/neu dan p53 dengan gambaran diferensiasi sel, respons kemoterapi dan survival, akan tetapi didapatkan hubungan yang bermakna antara variabel klinis jenis tindakan operasi, stadium, dan diferensiasi sel dengan respons kemoterapi dan survival. [Maj Obstet Ginekol Indones 2008; 32-4: 193-205] Kata kunci: over ekspresi, Her-2/neu, p53, respons kemoterapi, survival.

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