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Perception and Quality of Breakfast on Primary School Children Atika Putri Indrasari; M. Mutalazimah; Dewi Kumalasari; Ajeng Puspa Buana
Journal of Nutraceuticals and Herbal Medicine Vol 1, No 1 (2018): JNHM 2018
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v1i1.5739

Introduction: The determination of nutrition in breakfast is done by observing the quality of breakfast, such as the variety of food and the energy intake. One of the factors that influence the quality of breakfast is perception. Based on the results of preliminary survey, approximately 65% of students less understand about the importance of breakfast. Objective: This study aimed to determine the relationship between perception and the quality of breakfast, including food variety and energy intake, on primary school children at Madrasah Ibtida’iyah Muhammadiyah (MIM) Innovative Gonilan Kartasura. Methods: It is an observational study with cross sectional approach and sample size of 57 children were selected by simple random sampling. Perception was measured using a Likert scale questionnaire, the variety of food was measured using a questionnaire of food variation and the assessment of energy intake was done through interview using a 24-hour food recall form, then analyzed by Pearson product moment correlation test and Spearman rank test. Results: The perception of breakfast was considered adequate by 66.7%,the variety of food was classified as less by 50.9% and energy intake was considered more by 93%. Conclusion: there is no correlation between perceptions of breakfast and variety of food (p= 0,651) and energy intake (p= 0,696).

The effect of Salam Leaves Extract (Syzygium Polyanthum Wight.) on Urine Volume in The Potassium Oxonic-Induced Hyperuricemia Mice Muhtadi Muhtadi
Journal of Nutraceuticals and Herbal Medicine Vol 2, No 1 (2019): JNHM 2019
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v2i1.7637

This study aims to determine how Salam (Syzygium polyanthum Wight.) leaves extracts affect the urine volume of potassium oxonic-induced mice. Fifteen Swiss male mice were divided into 3 groups. Group I (normal group) were given intraperitoneal aquadest 1 mL/20g.bw, group II (negative group) and group III (Salam leaves extracts group) were given intraperitoneal 250 mg/kg.bw of potassium oxonic. After 1 hour of the treatment, group I and group II were given aquadest 0.5 mL/20g.bw orally, while group III was given Salam leaves extracts 200 mg/kg.bw orally. Mice are included in metabolic cage. The cumulative urine volume data were analyzed by Kruskal-Wallis and and Mann-Whitney test with a confidence level of 95%. In the urine volume profile test, the negative group did not experience a significant increase in urine volume when compared with the Salam leaves extracts group at hyperuricemia for 3 days (p 0.05), while the negative group had higher urine volume when compared to the normal group (p = 0.007). The results of this study indicated that Salam leaves extracts were not able to increase urine volume in hyperuricemic conditions.

Anti Inflammatory Activity Test of Ethanol Extract of Fennel Leaves and Fruits (Foeniculum Vulgare Mill.) In Wistar Rats Ahwan Abdul
Journal of Nutraceuticals and Herbal Medicine Vol 3, No 2 (2020): JNHM 2020
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v3i2.12847

Fennel plant has various kinds of benefits such as anti-inflammatory. Fennel plants contain alkaloid compounds, flavonoids, saponins, polyphenols, tannins, anthraquinones, and steroids. The research objective was to determine the anti-inflammatory activity of the ethanol extract from fennel leaves and fruit. The research method belongs to experimental research with edema formation on rats' feet induced by 1% carrageenan. The animals' tests were randomly divided into eight treatment groups and measured the volume of their feet. Each group was given CMC Na 1% (negative control), diclofenac sodium 4.5mg/Kg weight rats (positive control), and ethanol extract of fennel leaves and fruit at a dose of 87.5 mg/Kg rat body weight, 175 mg/ Kg rat body weight, 350 mg/Kg rat body weight. Moreover, the animals' tests were induced with carrageenan 1% while the edema volume of rat leg was measured at the hours of 0.25; 0.5; 0.75; 1; 1.25; 1.5;1.75; 2.00 after induction of carrageenan. The results of the study were edema volume data and AUC value for each treatment. The data were analyzed using the Kolmogorov-Smirnov (normality test), Levene test (homogeneity test), and One-Way Anova (effectiveness test). The normality and homogeneity test results show that there is no significant difference (P0.05). In contrast, the effectiveness test between CMC Na 1% (negative control) and Diclofenac sodium 4,5 mg / Kg weight (positive control) shows the significant result (P0.05), CMC Na (negative control) and all extract treatment shows the insignificant result (P0.05), Diclofenac Natrium 4,5 mg/ Kg weight (positive control) with all treatments indicates the significant result (P0.05).

Cytotoxicity of Mangrove Leaves (Rhizophora) Ethanolic Extract on Cancer Cells Haryoto Saroyo; Nur Fajariyah Maulidah Saputri
Journal of Nutraceuticals and Herbal Medicine Vol 4, No 1 (2021): JNHM 2021
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v4i1.15657

Cancer is a disease that can attack any part of the body when the abnormal cells begin to grow uncontrollably beyond the limit, then attack the connected parts of the body and spread to other organs. The mangrove (Rhizophora) is a herbal plant that can be used as a treatment for various diseases, one of which is cancer. The mangrove (Rhizophora) plant contains phytochemicals ranging from fruit, seeds, leaves and roots. This review article aims to examine the cytotoxicity effects of mangrove (Rhizophora) plants on cancer cells. The library sources in this article review use the Google Scholar and PubMed databases. The inclusion criteria used were articles containing the cytotoxic test of mangrove (Rhizophora) with the last 10 years of publication (2011-2020), original research, there were results of anticancer activity in the form of IC50 and research using mangrove (Rhizophora). plant extracts. The exclusion criteria used were articles that did not contain a full text, used plants with different genus, did not have an IC50 value and were not original research. From the journals that have been analyzed, it can be said that the extract of the mangrove (Rhizophora) plant can be developed for cancer treatment. The mangrove (Rhizophora) plant has cytotoxic activity because it contains active compounds in the form of phenolic, flavonoids and terpenoids. Based on the results of the cytotoxic test of mangrove (Rhizophora) extract, the plant parts that have the strongest cytotoxic effect are fruit.

The Formulation of Rambutan Leaf (Nephelium lappaceum L.) Extract on Syrup Preparation Derry eviana Pratiwi
Journal of Nutraceuticals and Herbal Medicine Vol 3, No 1 (2020): JNHM 2020
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v3i1.8064

Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia due to the abnormal metabolism of carbohydrates, fats, and proteins. Flavonoids are compounds that can reduce glucose levels in the blood. Rambutan leaves (Nephelium lappaceum L) are one of the plants that contain flavonoids. This research is an experimental study at producing concentrations of syrup for diabetes treatment with various propylene glycol as cosolvent. Rambutan leaves were extracted using the maceration method with 96% ethanol. Rambutan leaf extract made syrup preparations using propylene glycol with concentrations of 0%, 11%, 12%, and 13%. Syrup obtained by testing included: organoleptic, homogeneity, BJ, pH, viscosity, displaced volume, and acceptability. Based on the research on rambutan leaf extract formulation on syrup preparations showed that the addition of propylene glycol has an effect on taste which is giving a sweet taste so that the addition of propylene glycol can improve the taste in the preparation of rambutan leaf extract syrup. The concentration of propylene glycol 11% produced a preparation of rambutan leaf extract with the best physical stability.

Antioxidant Activity Using DPPH & Frap Method and Their Correlation with The Levels of Phenolic and Flavonoid Compounds from Nemba Plants (Azadirachta Indica A. Juss) Haryoto Saroyo; Ismi Aziz Nur Arifah
Journal of Nutraceuticals and Herbal Medicine Vol 3, No 2 (2020): JNHM 2020
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v3i2.15658

One of the herbal plants, namely neem (Azadirachtaindica A. Juss) can generally be used as an ingredient for traditional medicine. Neem is known to have the potential to produce antioxidants, where it can play an important role in counteracting free radicals. As a result of the increasing number of free radicals, the number of antioxidants and free radicals becomes unbalanced. If this continues, it can cause problems, namely the emergence of various kinds of serious diseases. The purpose of this literature review is to present articles related to the potential for antioxidant activity; content of phenolic compounds and flavonoids; knowing whether there is a relationship between phenolic compounds and flavonoids on antioxidant activity; as well as providing information related to other potentials of neem (Azadirachta indica A. Juss) plants. Several studies have stated that the neem plant has antioxidant activity. The strongest antioxidant activity was found in the neem root. The secondary metabolites produced are alkaloids, flavonoids, steroids, polyphenols, glycosides, phenols, tannins, essential oils, carotenoids, fatty acids, and saponins. Another study also stated that neem has the potential for other pharmacological activities such as antibacterial, immunomodulatory, antidiarrheal, and antifungal activities. polyphenols, glycosides, phenols, tannins, essential oils, carotenoids, fatty acids, and saponins. Another study also stated that neem has the potential for other pharmacological activities such as antibacterial, immunomodulatory, antidiarrheal, and antifungal activities. polyphenols, glycosides, phenols, tannins, essential oils, carotenoids, fatty acids, and saponins. Another study also stated that neem has the potential for other pharmacological activities such as antibacterial, immunomodulatory, antidiarrheal, and antifungal activities.

Literature Review: Study of Antibacterial Activity of Sunflower (Helianthus Annuus L.) Extract and Its Phytochemical Profiles Rifka Amirul
Journal of Nutraceuticals and Herbal Medicine Vol 3, No 2 (2020): JNHM 2020
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v3i2.15644

Sunflower is one type of plant that grows in Indonesia. Sunflower plants contain secondary metabolites that have antibacterial activity. This study was conducted using a literature review approach to determine the antibacterial activity of sunflowers. The steps taken in this literature review are to collect, identify, evaluate, and interpret the antibacterial activity of sunflowers. Search results from keywords “Sunflower”, “antibacterial”, and “phytochemical profile” obtained as many as 1,834 articles, from several articles search results were then reviewed and obtained 8 articles that matched the inclusion and exclusion criteria. Various antibacterial activities of sunflower are effective against Escherichia coli, Pseudomonas aeruginosa, Micrococcus luteus, Staphylococcus aureus, Bacillus subtilis, Propionibacterium acnes, Streptococcus uberis, and Aspergillus brasiliensis. The results of phytochemical screening of sunflower leaves revealed the presence of terpenoids, sesquiterpenoids, triterpenoids, and steroids. The bioactive components found in sunflower leaves include Heliannuol M, Heliannuol D, helivypolides K, helivypolides L, helieudesmanolide, tambulin, pinoresinol and sesquiterpene 10-oxo-isodauc-3-en-15-al. Factors that affect antibacterial activity include ozonation conditions, acidity value, and oil concentration. Overall it can be concluded that sunflower extract can inhibit bacterial growth.

Development of Herbal Toothpaste Formulation with Combination of Binahong and Stevia (Stevia Rebaudina) Leaves Extract and Lemon Juice Hidayaturrahman Rahman
Journal of Nutraceuticals and Herbal Medicine Vol 3, No 1 (2020): JNHM 2020
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v3i1.10548

Toothpaste is the most important thing for oral health. A common problem that is susceptible to society is dental caries caused by Streptococcus mutants. Stevia leaves are widely used as a natural sweetener for food and beverage products that have low calories and are beneficial for health. Binahong leaves have traditional medicinal properties such as antibacterial. The content of vitamin C on the skin of a lemon has the potential to whiten teeth and prevent thrush. These three natural ingredients are used to make toothpaste. This research aims to make an effective and safe herbal toothpaste using a combination of stevia leaf extract, binahong leaf, and lemon peel flavoring. Binahong leaf extract is taken by a maceration method with a storage period of 7 days, stevia leaf 5 days, and lemon peel 3 days. The volumes of stevia leaf extract, binahong leaf and lemon peel used for each formulation were 0 ml, 0.5 ml, 1 ml, and 1.25 ml. To obtain toothpaste that has efficacy and safety, a series of tests are carried out starting from the organoleptic test, homogeneity test, spreadability test, and pH test. The pH of the toothpaste produced during the three weeks of testing fulfilled the SNI standard (12-3524-1995), which was 8.08-8.69 while the spread of toothpaste was quite good when applied to a toothbrush.

Inhibition Activity of Leaves, Flower and Root Extracts of Ruellia tuberosa L on α-Glucosidase Enzymes Andi Suhendi; Agus Salim Maulana
Journal of Nutraceuticals and Herbal Medicine Vol 3, No 2 (2020): JNHM 2020
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v3i2.15646

Previous study stated that the herba of Ruellia tuberosa L has inhibition activity on α-glucosidase enzymes. The leaves, flowers, and roots of Ruellia tuberosa L contain flavonoids but have different activities. This study aims to determine the inhibitory activity by the leaves, flowers and roots of Ruellia tuberosa on the α-glucosidase enzyme. Extraction was performed by maceration method using ethanol 96% as solvent. Inhibition activity was measured based on the formation of a yellow solution of p-nitrophenol compound as a result of the reaction between p-nitrophenyl-α-D-glucopyranoside (as substrate) and α-glucosidase enzyme at a wavelength of 405 nm. The system reaction of inhibition study is divided into two reactions, namely S0 (contains substrates without enzyme) and S1 (contain substrate and enzyme). The results showed that inhibition activities of leaves, flower and root extract were 9.97 ± 4.97 % at 7.8125 µg/mL concentration of extract; 13.98 ± 5.18 % at 7.8125 µg/mL concentration of extract; 99.08 ± 0.12 % at 31.25 µg/mL concentration of extract, respectively. Based on data, the extract of leaves, flowers and roots of Ruellia tuberosa L. has the potential as an inhibitor of the enzyme α-glucosidase.

Testing Antioxidant Activity of Plumeria Alba and Plumeria Rubra Ethanolic Extracts Using DPPH and Frap Methods and Determining Their Total Flavonoid and Phenolic Levels Muhtadi Muhtadi; Aulia Ayu Fatkhurrohmah Wiyono
Journal of Nutraceuticals and Herbal Medicine Vol 3, No 2 (2020): JNHM 2020
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v3i2.15643

Plumeria sp. or Frangipani with local name; Kamboja plants have been reported to have antimicrobial, anticancer, and antioxidant activities spread in every part of the plant. Previous studies that have been carried out only reported antioxidant activity in certain parts with certain methods. This study compared the most potent antioxidant activity in several parts of the plant with different methods with statistically significantly different results. This study aims to determine the antioxidant activity of Plumeria alba L. and Plumeria rubra L. by DPPH and FRAP methods and to determine the total flavonoid and phenolic levels. The methods used are two different methods, namely the DPPH and FRAP methods. Antioxidant activity test using the DPPH method showed that the highest antioxidant activity was found in P. rubra flowers with an IC50 value of 150, 20 ppm while in the FRAP method the highest activity was in P. rubra leaves with an antioxidant activity value of 79.75 mg AAE / g extract. The highest flavonoid content was found in the sample extract of P. rubra leaves with 117.83 mg quercetin equivalent/g extract, while the highest total phenolic content was found in P. rubra flowers with 108.85 mg gallic acid equivalent/g extract. The results showed that the highest antioxidant activity using the method DPPH correlated with phenolic content while the FRAP method correlated with flavonoid content. Antioxidant activity in P. rubra leaves comes from flavonoid compounds while in P. rubra flowers come from phenolic compounds. So that each plant sample can have a source of antioxidant activity from different compounds.

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Contact Name
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Contact Email
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Phone
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Journal Mail Official
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Editorial Address
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Location
Kota surakarta,

Jawa tengah

INDONESIA