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Journal of Nutraceuticals and Herbal Medicine
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Core Subject : Health,
Journal of Nutraceuticals and Herbal Medicine contains peer-reviewed article and research dedicated to advancing the scientific knowledge base of health, especially health nutrition, nutraceuticals, nutrition formula for human essential and functional food. This journal includes original research concerning the herbal medicine phytochemical, phytopharmacy, phytopharmacology, phytotheraphy.
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Articles 37 Documents
Consumption of Cariogenic Food and Nutritional Status of Children in PAUD Ummu Aiman Kartasura Sukoharjo Nurul afifa; Muwakhidah Muwakhidah
Journal of Nutraceuticals and Herbal Medicine Vol 3, No 1 (2020): JNHM 2020
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v3i1.6432

Abstract

The state of infection and food intake is a direct factor affecting nutritional status. The frequency of children consuming cariogenic foods that generally contain many carbohydrates can certainly affect the child's nutritional intake. If it happens for a long time and is not offset by variations of nutritious food, then the child will deficiency other macronutrients and micronutrients. Based on a preliminary survey conducted in PAUD UMMU AIMAN Kartasura Sukoharjo, known 3% of children had more nutrition, 10% had undernutrition, and 87% were normal. The objective of this was study to know the relationship between cariogenic food consumption with nutritional status in children aged 3-5 years in PAUD UMMU AIMAN Kartasura Sukoharjo. The method of this study was an observational study with a cross-sectional study design. The frequency data of cariogenic food consumption was obtained by using a food frequency (FFQ), nutritional status data was obtained by using direct measurement of height and weight of the student. Data were analyzed using Fisher's Exact Test. The result was 52.8% of respondents had low cariogenic food consumption levels, and 47.2% had high levels of dietary cariogenic consumption. That as many as 13.9% of respondents have abnormal nutritional status, while 86.1% have normal nutritional status. There was a correlation between consumption of cariogenic food and nutritional status (p = 0.016).
Correlation of Phenolic Content of Multiflora Honey from Malang and Alastuwo to Activity Antioxidant Using DPPH (2.2-Diphenyl-1-Pickrylhydrazyl) Ahwan Abdul
Journal of Nutraceuticals and Herbal Medicine Vol 4, No 1 (2021): JNHM 2021
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v4i1.15581

Abstract

Honey contains various compounds that function as antioxidants, one of which is phenolic compounds. The purpose of this study was to determine the correlation between the phenolic content of multiflora honey from Malang and Alastuwo on antioxidant activity using the DPPH method (2,2-Diphenyl-1-picrylhydrazyl). Qualitative test of phenolic compounds with FeCl3 color reagent, determination of total phenolic content by UV-Vis spectrophotometry using Folin-Ciocalteu method and antioxidant activity test using DPPH method (2,2-Diphenyl-1-picrylhydrazyl). The results showed that qualitatively Malang and Alastuwo honey contained phenolic compounds. The total phenolic content of Alastuwo honey was 0.0278 ± 0.0010 mg GAE/g and Malang honey was 0.0301 ± 0.0004 mg GAE/g. The results of the antioxidant activity test showed that Alastuwo honey had weak antioxidant activity (IC50 of 393.37 ± 10.28 ppm), Malang honey had moderate antioxidant activity (IC50 of 217.20 ± 6.61 ppm) and vitamin C had strong antioxidant activity. (IC50 is 2.22 ± 0.19 ppm). The total phenolic content of Alastuwo and Malang honey correlates with its antioxidant activity.
Antioxidant Activity of Sunflower (Helianthus Annuus l.) Ethanolic Extract with DPPH Method and Determination of Total Phenolic and Flavonoid Levels Salwa Salwa
Journal of Nutraceuticals and Herbal Medicine Vol 4, No 1 (2021): JNHM 2021
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v4i1.15642

Abstract

Sunflower (Helianthus annuus L.) is believed to have antioxidant properties. Currently, there are many studies examining compounds that have benefits as antioxidants and are safe for health. However, the sunflower only examined the antioxidants in sunflower seeds. This study aims to determine the antioxidant activity of ethanol extract of flowers, bark, and leaves of sunflowers. The antioxidant activity test using the DPPH method showed the highest antioxidant activity was found in the leaf extract (Helianthus annuus L.) with an IC50 value of 48.841 ppm. The highest phenolic content was found in leaf samples with a value of 35.149 mg gallic acid equivalent/gram extract and the highest determination of flavonoid levels was found in leaf samples with a value of 10.917 mg quercetin equivalent/gram extract.
The Influence of Zinc (Zn) Intake with Stunting Toddlers in Surakarta Artia Happy Aprilitasari; Muwakhidah Muwakhidah
Journal of Nutraceuticals and Herbal Medicine Vol 3, No 1 (2020): JNHM 2020
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v3i1.6431

Abstract

Stunted growth of toddlers is caused by the disturbance in the content, lack of micronutrients, less energy intake, and infectious diseases that are caused by stunting in children aged under five years old. Preliminary study results were conducted in the city of Surakarta the highest stunting prevalence in the work area Puskesmas Penumping. Based on data of weighing results in February 2016, the highest prevalence was in Kelurahan Panularan with very short children aged 12-36 months old as many as 22 (12.71%) toddlers and short toddlers as many as 29 (16.76%) toddlers. The purpose of this research is to know the intake of zinc and calcium in stunting toddlers in Surakarta City. The results of this quantitative study using a cross-sectional approach with the number of respondents 71 toddlers obtained by proportional random sampling technique. The data of food intake was obtained through 24-hour recall interviews for three consecutive days and nutritional status data was obtained from measurement of height and weighing children. Data analysis using Independent T-Test. From the result of research known that zinc (Zn) toddler stunting and non-stunting averaging 181,43 ± 197. According to the results of a bivariate analysis, there was no difference in zinc intake with stunting and non-stunting events in children aged 12-36 months (p = 0.223).
Antibacterial Activity of Combination of Ethanol Extract of Pepermine Leaves (Mentha piperita L.) and Amikacin Against Klebsiella pneumonia, Staphylococcus aureus, and Escherichia coli Peni Indrayudha
Journal of Nutraceuticals and Herbal Medicine Vol 4, No 1 (2021): JNHM 2021
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v4i1.15649

Abstract

Peppermint leaves have been known to have antibacterial and antifungal activity. Amikacin is a semisynthetic derivative of kanamycin which is active against both Gram-positive and Gram-negative enteric bacteria. The combination of plant extracts with antibiotics is one way or alternative to overcome bacterial resistance to antibiotics. The purpose of this study was to determine the combined effect of the ethanolic extract of peppermint (Mentha piperita L.) and amikacin against Klebsiella pneumonia, Staphylococcus aureus, and Escherichia coli as well as the compounds contained in the ethanolic extract of peppermint (Mentha piperita L.) leaves. Antibacterial activity was tested using the disk diffusion method (Kirby Bauer) and the phytochemical screening test using the tube test method. The concentration of peppermint leaf ethanol extract for the combination test was 200 mg/mL and 400 mg/mL, for the concentration of amikacin used was 5 mg/mL with three comparisons made, namely 25:75, 50:50, and 75:25. The results showed a synergistic effect with the largest inhibition zone diameter at a ratio of 25:75 at a concentration of 200 mg/mL, which was 36.25±2.5 mm on Klebsiella pneumonia bacteria. While at a concentration of 400 mg/mL the diameter of the largest inhibition zone was 40±1.63 mm in Klebsiella pneumoniae bacteria with a ratio of 75:25. The results of statistical tests using the t-test showed a significance value of 0.000 0.05 so that there was a significant difference in the administration of each concentration to the resulting inhibition zone. The results of the phytochemical screening test contained alkaloids, phenolic compounds, flavonoids, tannins.
Tests of Ash Content, Moisture Content and Dry Shrinkage of Ethanol Extracts of Capidada Leaves (Sonneratia alba) and Ketapang (Terminilia cattapa) Annisa Meyndra Komala; Haryoto Haryoto
Journal of Nutraceuticals and Herbal Medicine Vol 3, No 1 (2020): JNHM 2020
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v3i1.10549

Abstract

Indonesian original medicine requires new development, one of the important stages is by testing which can be used as a parameter to determine standards for certain extracts. Capidada leaves (Sonneratia alba J. Smith) and ketapang leaves (Terminalia cattapa L.) are a type of mangrove that have various activities such as anti-bacterial, anti-inflammatory, antioxidant, as well as the benefits of capidada leaves and ketapang leaves. Therefore, it is necessary to standardize extracts to ensure quality that matches the quality. This research tries to test the water content, ash content, and drying shrinkage levels, which later can be used as a reference for the determination of extract quality standards. The extract was obtained through maceration using 96% ethanol. Test results obtained on capidada leaves are water content (10,38 ±0,52%v/b), total ash content (17,97±1,75%), drying shrinkage levels (10,35±0,35%), and the test results obtained for the ketapang leaves are water content (7,08±0,38%), total ash content (10,51±0,43%) and drying shrinkage levels (13,67±1,58%). To find out all aspects that are not directly related to pharmacological activities but affect the aspects of quality, safety, the stability of extracts and preparations produced, this research studied the ash content, water content, and drying shrinkage levels on ethanol extracts of mangrove capidada leaves (Sonneratia alba) J. Smith.) And ketapang (Terminalia cattapa L.)
Formulation of Mouthwash Preparations Ethanol Extract of Coffee Beans Roasted Robusta (Coffea canephora) and Effectiveness Test on Bacteria Streptococcus mutans Syaifur Rahman; Reni Ariastuti; Ahwan Ahwan
Journal of Nutraceuticals and Herbal Medicine Vol 4, No 1 (2021): JNHM 2021
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v4i1.15670

Abstract

Dental caries can be caused by Streptococcus mutans bacteria. Robusta coffee bean extract has an inhibitory effect on the growth of Streptococcus mutans bacteria. Compounds that have antibacterial activity are chlorogenic acid (CGA), caffeine, caffeic acid and trigonelline. Robusta coffee bean extract has the potential to be formulated into mouthwash. This study aims to make a mouthwash formula with the active ingredient of roasted Robusta coffee extract and then evaluate the preparation and test its effectiveness against S. mutans bacteria. Mouthwash preparations were made in 3 formulas with different glycerin concentrations, namely 5%, 10%, and 15%. The stability test of the preparation used the treatment before and after the forced condition. Bacterial inhibition test using agar diffusion method with the positive control, namely commercial mouthwash Chlorhexidine and negative control mouthwash formula without extract content. Data analysis used the Kruskal-Wallis test to determine the differences in each treatment, and the Mann-Whitney test to see which treatment groups were significantly different. The results of the evaluation of the stability of the preparation showed that the three formulations of the mouthwash of roasted Robusta coffee bean extract had organoleptic stability, pH, and viscosity. The results of the inhibitory effectiveness test showed that the mouthwash formulation of formula 1 produced an inhibition zone of 1.6 mm, formula 2 of 2.1 mm, formula 3 of 2.4 mm, positive control of 6.8 mm, and negative control did not produce obstacles zone. It can be concluded that the three mouthwash formulas have antibacterial activity in the weak category (5 mm). The concentration of glycerin in the formula had no significant effect on the stability of the preparation and the antibacterial effectiveness of S. mutans. The results of the inhibitory effectiveness test showed that the mouthwash formulation of formula 1 produced an inhibition zone of 1.6 mm, formula 2 of 2.1 mm, formula 3 of 2.4 mm, positive control of 6.8 mm, and negative control did not produce obstacles zone. It can be concluded that the three mouthwash formulas have antibacterial activity in the weak category (5 mm). The concentration of glycerin in the formula had no significant effect on the stability of the preparation and the antibacterial effectiveness of S. mutans. The results of the inhibitory effectiveness test showed that the mouthwash formulation of formula 1 produced an inhibition zone of 1.6 mm, formula 2 of 2.1 mm, formula 3 of 2.4 mm, positive control of 6.8 mm, and negative control did not produce obstacles zone. It can be concluded that the three mouthwash formulas have antibacterial activity in the weak category (5 mm). The concentration of glycerin in the formula had no significant effect on the stability of the preparation and the antibacterial effectiveness of S. mutans.

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